For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3064 (-)

annotation: putative PE family protein
coordinates: 2777389 - 2778558
length: 390

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3064--100% (390)putative PE family protein
M. thermoresistible (build 8)TH_3545-5e-0822.90% (310) PUTATIVE -
M. thermoresistible (build 8)TH_3554-1e-0532.65% (147) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1205cPE124e-3245.26% (137) PE family protein
M. gilvum PYR-GCKMflv_2738-2e-1227.27% (308) hypothetical protein Mflv_2738
M. tuberculosis H37RvRv1172cPE122e-3234.50% (229) PE family protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2679-9e-2027.86% (384) hypothetical protein MAB_2679
M. marinum MMMAR_4280-1e-3236.45% (214) PE family protein
M. avium 104MAV_4848-4e-0728.41% (176) hypothetical protein MAV_4848
M. smegmatis MC2 155MSMEG_5127-3e-1622.75% (378) hypothetical protein MSMEG_5127
M. ulcerans Agy99MUL_1019-2e-3035.29% (221) PE family protein
M. vanbaalenii PYR-1Mvan_3794-4e-1226.04% (361) hypothetical protein Mvan_3794

CLUSTAL 2.0.9 multiple sequence alignment


Mb1205c|M.bovis_AF2122/97           --MSFVFAAPEALAAAAADMAGIGSTLNAANVVA-------------AVP
Rv1172c|M.tuberculosis_H37Rv        --MSFVFAAPEALAAAAADMAGIGSTLNAANVVA-------------AVP
MMAR_4280|M.marinum_M               --MSYVAAVPEALTAAASDVAGIGTTISSANAAA-------------SAP
MUL_1019|M.ulcerans_Agy99           --MSYVATVPEALTAAASDAAGIGTTISSANAAA-------------SAP
Mflv_2738|M.gilvum_PYR-GCK          MGNEMHASIRAALAAGVTTLTASALAFAPPPQPP-------------AAQ
Mvan_3794|M.vanbaalenii_PYR-1       ----MNVSARAALAAGVTALTGGALMFTPSVLPATMSTVEVVRPVAFAAD
MAB_2679|M.abscessus_ATCC_1997      ----MDRTANPLFKAGMAAITATALIVAPAVTPPTRQSIPLP-----DIR
TH_3064|M.thermoresistible__bu      ----------------VAAVGAAAVAFAPVQALPP------------DIA
MSMEG_5127|M.smegmatis_MC2_155      ----MTVSVRAYLMAGAAAATATTIALTSVQVTPP------------DVV
MAV_4848|M.avium_104                ----MDIVLGVSMAPGTVRLVAIEGQNADGVTVEQE-----------EFA
                                                         .                            

Mb1205c|M.bovis_AF2122/97           TTGVLAAAADEVSTQVAALLSA-HAQGYQQLSRQMMTAFHDQFVQALRAS
Rv1172c|M.tuberculosis_H37Rv        TTGVLAAAADEVSTQVAALLSA-HAQGYQQLSRQMMTAFHDQFVQALRAS
MMAR_4280|M.marinum_M               TTGVLAAAGDQVSAQVAALFSS-HGEIYQRLSSQLST-FHDQFAAALNTS
MUL_1019|M.ulcerans_Agy99           TTGVLAAAGDQVSAQVAALFSS-HGEIYQRLSSQLST-FHDQFAAALNTS
Mflv_2738|M.gilvum_PYR-GCK          ALSVQPLS-----IASEMVSAASFTAG----STRILPVTDPRALAALTAF
Mvan_3794|M.vanbaalenii_PYR-1       GTPITPVSDDDVRAALELIGNLGSVAGPRKVTVRLGGHDHPEAARAILPT
MAB_2679|M.abscessus_ATCC_1997      SASVRLSSLAFTPRAAEVPASPLAALKLSLSPASAAPASPLKRAPLGQLA
TH_3064|M.thermoresistible__bu      VTAEQPVLDASASREAVALLAAVQGLAVRPASPPVAP-----TAPTPDEV
MSMEG_5127|M.smegmatis_MC2_155      VPAQPTAPQPELTQAMVDLLAA----------------------ARRTTI
MAV_4848|M.avium_104                VGAAGNSANSAADQVIDAIIGTREGVFEGGHRLTSTGVTWTDPTGAAALR
                                                                                      

Mb1205c|M.bovis_AF2122/97           ADAYATAEASAAQTMVNAVNAPARALLGHPLIS-ADASTGGGSNALSRVH
Rv1172c|M.tuberculosis_H37Rv        ADAYATAEASAAQTMVNAVNAPARALLGHPLIS-ADASTGGGSNALSRVQ
MMAR_4280|M.marinum_M               ANSYASAEANAAKTLLSAVNSPAEKLLGQPLMG-QGGIV---ANAVSQVQ
MUL_1019|M.ulcerans_Agy99           ANSYASAEANAAKTLLSAVNSPAEKLLGQPLMG-QGGIV---ANAVSQVQ
Mflv_2738|M.gilvum_PYR-GCK          TQPWPGTPSDAADPTDLATVTTADEPLEDPVALNAASDVIDTVYAFTRYW
Mvan_3794|M.vanbaalenii_PYR-1       ARVVDAGGTDPAS-VDAPAAAADGQALDEPVAQNAASDLIDTVYSISRYW
MAB_2679|M.abscessus_ATCC_1997      TAVQPRAAAAPLPTPVSAPTQPDAATASSPVVASSLTNGIDQAYQFIQYW
TH_3064|M.thermoresistible__bu      QAAVTAIQELAAPGAPATTAAADSAIEVGTAAFPGAANAIKDVYNLIEPY
MSMEG_5127|M.smegmatis_MC2_155      TIPVPPDAPRVAPPHGNAAPDAQATASGDVTVQNAASDFVVDAWEAAVPW
MAV_4848|M.avium_104                DAIASHELGNVMLVSPLLAAAALAQTVGYALGYGHIGMLFVEPRSATLAV
                                                         .                            

Mb1205c|M.bovis_AF2122/97           SMFLGTGG-SSALGGSAAAN-AAASGALQLQPTGGASGLSAVGALLPRAG
Rv1172c|M.tuberculosis_H37Rv        SMFLGTGG-SSALGGSAAAN-AAASGALQLQPTGGASGLSAVGALLPRAG
MMAR_4280|M.marinum_M               SVFAGAG--SNALG--------ANASMLALAPTGGAATAAASGSLLG-PI
MUL_1019|M.ulcerans_Agy99           SVFAGAG--SNALG--------ANASMLALAPTGGAATAAASGSLLG-PI
Mflv_2738|M.gilvum_PYR-GCK          ANYVSLELGPWLINWVPFGY-LISDQILIWYPNFVLPVVDSFVYDFLDPV
Mvan_3794|M.vanbaalenii_PYR-1       ANYVSLELGPWLINWIPFGY-LISDQIYIWYPDFVLPVVDSFVYDFLDPV
MAB_2679|M.abscessus_ATCC_1997      VDY-GVDLAQWGAGFVPVIGGLVSAQIGIVYDNLVRPIANSFVYNLVDPI
TH_3064|M.thermoresistible__bu      VAW-GVEVAQWAVGWVPWVG-LLSGQIGIFY-TFGEAIVYSVVFNVADWI
MSMEG_5127|M.smegmatis_MC2_155      IDY-GVGLVDGALGWVPGLA-IVGNQVSLLWTYLGYPVANSVVLDLVAPV
MAV_4848|M.avium_104                VDVSDGSIVDLHRHQIPHGP-GAPVAAELAAMVAGLDARDTRADGVFVVG
                                        .                                   :    .    

Mb1205c|M.bovis_AF2122/97           AAAA-------------------------AALPALAAES---IGNAIKNL
Rv1172c|M.tuberculosis_H37Rv        AAAA-------------------------AALPALAAES---IGNAIKNL
MMAR_4280|M.marinum_M               ASAA-------------------------AAPAAILPVS---VATAIQNF
MUL_1019|M.ulcerans_Agy99           ASAA-------------------------AAPAAILPVS---VATAIQNF
Mflv_2738|M.gilvum_PYR-GCK          VNDP-------------------------LNLEVWAQGIGSIIDTAVAGV
Mvan_3794|M.vanbaalenii_PYR-1       VNDP-------------------------LNLNVWLDGIGDIINTALTGV
MAB_2679|M.abscessus_ATCC_1997      LNDPSFSNIVNSFGRFGSDIVNSVINFAWAEARYFLPPLPPLPGLALQTT
TH_3064|M.thermoresistible__bu      GGTVGFG----------------------EGLANIAAATSQAVTDLIRDE
MSMEG_5127|M.smegmatis_MC2_155      VNAP-------------------------LNLDVWANGFGAVASTTANSL
MAV_4848|M.avium_104                CGTD------------------------IVAVKPALEAASPVPVTGPEEP
                                                                                      

Mb1205c|M.bovis_AF2122/97           YNA--------VEPWVQYGFNLTAWAVGWLPYIGILAPQINF------FY
Rv1172c|M.tuberculosis_H37Rv        YNA--------VEPWVQYGFNLTAWAVGWLPYIGILAPQINF------FY
MMAR_4280|M.marinum_M               YLA--------VEPWVQYGFNLASWAVGWVPWIGILAPQINF------FY
MUL_1019|M.ulcerans_Agy99           CLA--------VEPWVQYGFNLASWAVGWVPWIGILAPQINF------FY
Mflv_2738|M.gilvum_PYR-GCK          RNG--------VTAEIQYILDFGWFPFPLPPLPSFPVPGAAG------AS
Mvan_3794|M.vanbaalenii_PYR-1       YNG--------VVGEIQYALSFDWFPIPLPPLPPFP-PLPIF------DA
MAB_2679|M.abscessus_ATCC_1997      TDANGAAPTSVHEALVPFTKAFKDAEAHFAEALGLTKPDPKS------AA
TH_3064|M.thermoresistible__bu      INWVRSFFPPLPPLPPVLPAALPMSLPTSLPTSEAHPAQQVG------IA
MSMEG_5127|M.smegmatis_MC2_155      VNTG------VAEFNYFFGWLIPPVALTTPTETLAFDATVGA------DL
MAV_4848|M.avium_104                DMALARGAALASANAPLFASSTAALAYALDPGTGEMDPPAFNPTYLDVWG
                                                                         .            

Mb1205c|M.bovis_AF2122/97           YLGEPIVQAVLFNAIDFVDG-------------TVTFSQALT--------
Rv1172c|M.tuberculosis_H37Rv        YLGEPIVQAVLFNAIDFVDG-------------TVTFSQALT--------
MMAR_4280|M.marinum_M               YLFEPIVQSGLFNTLDWLDG-------------TITFSQGLS--------
MUL_1019|M.ulcerans_Agy99           YLFEPIVQSGLFNTLDWLDG-------------TVTFSQGLSNF------
Mflv_2738|M.gilvum_PYR-GCK          AESADADVQLAS--VDEADA-------------AGAVEDAVEGAEGGAAE
Mvan_3794|M.vanbaalenii_PYR-1       ADSAPTEVTLASSETDGDET-------------GATAIEATDSDDTDAVT
MAB_2679|M.abscessus_ATCC_1997      LEKTGTAAQTGESLKETTGESVQEEGKTAETGAATGTKEALDRKESAEGK
TH_3064|M.thermoresistible__bu      KAGAAAEVAGSPTATTVVEG-------------DLPADEAPEPPAQAQRQ
MSMEG_5127|M.smegmatis_MC2_155      LKQARAAVTSLVEPAEGAEAAEAS--------EAPKAPESLESPEKPETK
MAV_4848|M.avium_104                DTGAGTGVRAYSAVPDEEEPAPRRPWSMLLAGGALAGIAAVIGGVVLVTL
                                                                           .          

Mb1205c|M.bovis_AF2122/97           ------------NIETATAASIN---------------------------
Rv1172c|M.tuberculosis_H37Rv        ------------NIETATAASIN---------------------------
MMAR_4280|M.marinum_M               ------------NFWSATTASVN---------------------------
MUL_1019|M.ulcerans_Agy99           -------SQGLSNFWSATTASVN---------------------------
Mflv_2738|M.gilvum_PYR-GCK          A--VEVDG---DDIVAQKPADVSGEAVDEALVEEESVEEESVDVVDEESV
Mvan_3794|M.vanbaalenii_PYR-1       D--VPVDDPITETVVTPAPEDAAGEEAPAGTAAEDEPE-TPVEDVEESVE
MAB_2679|M.abscessus_ATCC_1997      A--SANDKATAVAEKTKAGDKATTESREPVTTATEAAKESTKDSVKDAAV
TH_3064|M.thermoresistible__bu      P--VQRGALLAETDPVEDDSSAPDAGESPAPGVDVRPGPRPGTALRDSLQ
MSMEG_5127|M.smegmatis_MC2_155      TPDAPAAEFSAPAGTTENTASGVTENAENTEVVEDTTTPTKADTSTKAPV
MAV_4848|M.avium_104                TSDGHSTNTRHNQGVSVATPGIQLPAPPPSNPPAAQPPAPSTPAPAPTPT
                                                                                      

Mb1205c|M.bovis_AF2122/97           QFINTEINWIRGFLPPLPPISPPGFPSLP---------------------
Rv1172c|M.tuberculosis_H37Rv        QFINTEINWIRGFLPPLPPISPPGFPSLP---------------------
MMAR_4280|M.marinum_M               QFIQTEINWIRHFFPPFPPLP---F-------------------------
MUL_1019|M.ulcerans_Agy99           QFIQTEINWIRNFFPPFPPLP---F-------------------------
Mflv_2738|M.gilvum_PYR-GCK          EAVDDETDQVEETVDEESAEDGATTDDEPTDED-------APA---GSDS
Mvan_3794|M.vanbaalenii_PYR-1       DAVEEDADEASGETGAETPAPAEDTGADGPGTD-------EPASEPASDE
MAB_2679|M.abscessus_ATCC_1997      PGVAADSDAASGNLTKGTLAAKETGNQQQSATDGKPSPSSAPADKPDKPV
TH_3064|M.thermoresistible__bu      EVARAATASVEXXXX-GPPWPAGPAMPAPTGPPCSSPAGSAPPAPCAAFI
MSMEG_5127|M.smegmatis_MC2_155      KPVRTITKNIKRDLKKATAGLRGVVKDIRDGLVKPKKPATKPSKKAEPAK
MAV_4848|M.avium_104                EVAAPAPEPVQQAAPQTPVTTAPPAPVYRAPARPTPQYQPRPVEQPAPPP
                                                     .                                

Mb1205c|M.bovis_AF2122/97           --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4280|M.marinum_M               --------------------------------------------------
MUL_1019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK          GDDTSGSETE----------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1       KDSVAASASGD---------------------------------------
MAB_2679|M.abscessus_ATCC_1997      KPKVPAASTTEHGSISAQGIVRGPVSQSTSGQSGPSASTPKTADSKVSSS
TH_3064|M.thermoresistible__bu      TCSISELNIPVCPPSPPAP-------------------------------
MSMEG_5127|M.smegmatis_MC2_155      KAEPSKQSASESSSSDSDD-------------------------------
MAV_4848|M.avium_104                AAAPAPAAPPPAPAPPPAAPPVPHQPPVTMYLHFPFVTVPIPITPPAPPP
                                                                                      

Mb1205c|M.bovis_AF2122/97           --------------------------------------------------
Rv1172c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4280|M.marinum_M               --------------------------------------------------
MUL_1019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_2679|M.abscessus_ATCC_1997      GASGFQTSDTGTPESKMSDTKTATGTTAGTKATETKPKAAETKPSDAKSS
TH_3064|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155      --------------------------------------------------
MAV_4848|M.avium_104                GP------------------------------------------------
                                                                                      

Mb1205c|M.bovis_AF2122/97           --------------------------------------------
Rv1172c|M.tuberculosis_H37Rv        --------------------------------------------
MMAR_4280|M.marinum_M               --------------------------------------------
MUL_1019|M.ulcerans_Agy99           --------------------------------------------
Mflv_2738|M.gilvum_PYR-GCK          --------------------------------------------
Mvan_3794|M.vanbaalenii_PYR-1       --------------------------------------------
MAB_2679|M.abscessus_ATCC_1997      GSTTSGTKSPGTTAHDSANKPSASASSAAKSGGEGSKSSSGSHR
TH_3064|M.thermoresistible__bu      --------------------------------------------
MSMEG_5127|M.smegmatis_MC2_155      --------------------------------------------
MAV_4848|M.avium_104                --------------------------------------------