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MTRIGGDEHLVSEVETLVRRWLDDAAGHRVAPAARRLADVLRDPGGLDFTVGFVDRVIRPDDPRVAAANL RELARTAPGFLPWHLRLLIRLGAAVSVVLPGVVIPIASRALREMVGHLLADATDARLGRSIERIRRRGVN LNVNLLGEAVLGRREARRRLTGTERLLARPDVDYVSIKVSASVPPHSVWAFDEAVDHIEQSLLPLFTQAA TAATPKFINLDMEEYRDLELTMAVFTRLLDRPELRALEAGIVLQAYLPDALGAMIRLQDWARDRRQRGGA GIKVRLVKGANLPMEHVEASLHGWPVATWPTKQDTDTNYKRVLNYALQPDRIANVRIGVAGHNLFDVAYA WILAGRRGVRDGVEFEMLLGMADAQAEAVRATVGSLLLYVPVVHPEDFDVAIAYLVRRLEEGSSHQNFMS AVFELHSDDMLFQRERERFVASLAAVDDDVPLPNRRQDRRADDPAAAVRAEFSNVADTDPALPGNRAWGR AVTGRIAGSTAGRSAVDEHTVTTVDGLEAVISRGVDAGARWAALSGAERAAVLRRAAATLEARRATLLEV MAAETGKTLDQGDPEVSEAIDFANYYASLAEKLDRVDGAIARPVGLTVVTPPWNFPVAIPAGSTLAALAA GSAVVIKPTTQARRCGSVMVEALWDAGIGRDTLQLVHLDEGELGARLISDARVDRVILTGAFDTAALFRS FRPDLVLLAETSGKNAIVVTPHADVDLAVKDLVYSAFGHAGQKCSAASLGILVGSVARSARFRDQLVDAV TSLNVGYPTDPTVQMGPVIEPADGKLLRALTTLGPGEKWLVAPRQLDDSGRLWSPGVRTGVRRGSEFHLT EYFGPVLGLMEARDLDEAIAMQNQVDYGLTAGLHSLDRHEVERWIDRVEAGNAYVNRSTVGAVVARQPFG GWKKSAVGAGAKAGGPNYLIGLTDWESAPAQQAGRLSPAMREFLSAAGRLDLSAEDREFLGRSARSDALA WEQEFGIARDVAGLTAEKNVLRYRPVPVTVRAEDGHTASLLRVVAAGLLAGAAITVSTPAPPASAVADLL HMRGVTLRVDDAEHWRKLLRGNAPARVRLIGGSREAFAGAGEGRADVALYAQPVVEAGRIELLTFLREQA VAVTAHRFGSPTTLADGLFA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_2172 | - | - | 100% (1140) | aldehyde dehydrogenase |
M. gilvum PYR-GCK | Mflv_4799 | - | 1e-39 | 30.36% (494) | aldehyde dehydrogenase |
M. gilvum PYR-GCK | Mflv_4063 | - | 5e-36 | 27.69% (437) | betaine-aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2883c | aldC | 2e-38 | 29.83% (419) | aldehyde dehydrogenase |
M. tuberculosis H37Rv | Rv2858c | aldC | 2e-38 | 29.83% (419) | aldehyde dehydrogenase |
M. leprae Br4923 | MLBr_02573 | gabD1 | 5e-33 | 25.87% (429) | succinic semialdehyde dehydrogenase |
M. abscessus ATCC 19977 | MAB_0823 | - | 3e-44 | 32.13% (445) | aldehyde dehydrogenase |
M. marinum M | MMAR_1240 | pcd | 6e-42 | 32.03% (434) | piperideine-6-carboxilic acid dehydrogenase Pcd |
M. avium 104 | MAV_2521 | mmsA | 1e-38 | 27.87% (427) | methylmalonate-semialdehyde dehydrogenase |
M. smegmatis MC2 155 | MSMEG_6687 | - | 2e-45 | 30.68% (453) | aldehyde dehydrogenase, thermostable |
M. thermoresistible (build 8) | TH_2909 | - | 5e-38 | 27.61% (431) | PUTATIVE methylmalonate-semialdehyde dehydrogenase [acylating) |
M. ulcerans Agy99 | MUL_2647 | pcd | 6e-42 | 32.03% (434) | piperideine-6-carboxilic acid dehydrogenase Pcd |
M. vanbaalenii PYR-1 | Mvan_1856 | - | 1e-43 | 30.68% (440) | aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK MTRIGGDEHLVSEVETLVRRWLDDAAGHRVAPAARRLADVLRDPGGLDFT MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK VGFVDRVIRPDDPRVAAANLRELARTAPGFLPWHLRLLIRLGAAVSVVLP MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK GVVIPIASRALREMVGHLLADATDARLGRSIERIRRRGVNLNVNLLGEAV MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK LGRREARRRLTGTERLLARPDVDYVSIKVSASVPPHSVWAFDEAVDHIEQ MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK SLLPLFTQAATAATPKFINLDMEEYRDLELTMAVFTRLLDRPELRALEAG MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK IVLQAYLPDALGAMIRLQDWARDRRQRGGAGIKVRLVKGANLPMEHVEAS MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK LHGWPVATWPTKQDTDTNYKRVLNYALQPDRIANVRIGVAGHNLFDVAYA MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK WILAGRRGVRDGVEFEMLLGMADAQAEAVRATVGSLLLYVPVVHPEDFDV MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK AIAYLVRRLEEGSSHQNFMSAVFELHSDDMLFQRERERFVASLAAVDDDV MSMEG_6687|M.smegmatis_MC2_155 ---------------------MT-PVTINHLVAGDWVAGAGDVVVSVNPA Mvan_1856|M.vanbaalenii_PYR-1 ---------------------MTGPASVRHLIDGEWLPGGGDALVSVNPA MAB_0823|M.abscessus_ATCC_1997 ----------------------MHINEIQSFVGGRWISGGGQAVISVCPA MAV_2521|M.avium_104 --------------------MTAHTTLIPHFIDGRRSAGQSGRSADVFDP TH_2909|M.thermoresistible__bu -----------------------MTRQIHHFINGQHTAGQSTRTADVMNP Mb2883c|M.bovis_AF2122/97 -----------------------------------------MSTTQLINP Rv2858c|M.tuberculosis_H37Rv -----------------------------------------MSTTQLINP MLBr_02573|M.leprae_Br4923 ------------------------------------------MSIATINP MMAR_1240|M.marinum_M -------------MTHSDELRNRVRKAFEAIGVTASLDEPGGHGMPSSTP MUL_2647|M.ulcerans_Agy99 -------------MTHSDELRNRVRKAFEAIGVTASLDEPGGHGMPSSTP Mflv_2172|M.gilvum_PYR-GCK PLPNRRQDRRADDPAAAVRAEFSNVADTDPALPGNRAWGRAVTGRIAGST . MSMEG_6687|M.smegmatis_MC2_155 RPGDIVAEGHNATTAQVDTAVAAAAEAFRAWAATPTHQRGAVLLAAAQIV Mvan_1856|M.vanbaalenii_PYR-1 RPTVVVAEGSCAVASDVDAAVGAAAAAAPSWAATGMHQRGARLLAAAEIV MAB_0823|M.abscessus_ATCC_1997 FPDRVIAEGLAAGPAEFDEAAAAARAAQPGWAAMSLHARGAMLSHAAAVV MAV_2521|M.avium_104 STGGVQATVPMAGQADIDAAVASAVEAQKGWAATNPQRRARVMMRFVELV TH_2909|M.thermoresistible__bu STGKVQAKVVMGTAADIDAAVAGAAEAQKEWAAWNPQRRARVLMKFIDLV Mb2883c|M.bovis_AF2122/97 ATEEVLASVDHTDANAVDDAVQRARAAQRRWARLAPAQRAAGLRAFAAAV Rv2858c|M.tuberculosis_H37Rv ATEEVLASVDHTDANAVDDAVQRARAAQRRWARLAPAQRAAGLRAFAAAV MLBr_02573|M.leprae_Br4923 ATGETVKTFTPTTQDEVEDAIARAYARFDNYRHTTFTQRAKWANATADLL MMAR_1240|M.marinum_M ITCKTLFTLTATTAEQTERSIADAQAAFTQWRSTPAPVRGALVARLGELI MUL_2647|M.ulcerans_Agy99 ITCETLFTLTATTAEQTERSIADAQAAFTQWRSTPAPVRGALVARLGELI Mflv_2172|M.gilvum_PYR-GCK AGRSAVDEHTVTTVDGLEAVISRGVDAGARWAALSGAERAAVLRRAAATL : . : *. : MSMEG_6687|M.smegmatis_MC2_155 DRNAEAWGLELATEEGKTKAEGIGEVRRAAQILRYYGNEGDRQAGE--IF Mvan_1856|M.vanbaalenii_PYR-1 ERNAERWGLELATEEGKTRAEGVGEVRRAAQILRYYGNEGDRQAGE--IY MAB_0823|M.abscessus_ATCC_1997 DRNADAWGLELAAEEGKTKAEGIAEVRRAAQILRYYGNEGDRQTGE--IF MAV_2521|M.avium_104 NEHNDELAELLSREHGKTLADAKGDIQRGIEVIEFCVGIPHLLKGE--YS TH_2909|M.thermoresistible__bu NQNVDELAELLSLEHGKTLADAKGDIQRGIEVIEFSIGIPHLQKGE--YT Mb2883c|M.bovis_AF2122/97 QAHLDELAALEVANSGHPIVSAEWEAGHVRDVLAFYAASPERLSG----R Rv2858c|M.tuberculosis_H37Rv QAHLDELAALEVANSGHPIVSAEWEAGHVRDVLAFYAASPERLSG----R MLBr_02573|M.leprae_Br4923 EAEANQSAALMTLEMGKTLQSAKDEAMKCAKGFRYYAEKAETLLAD--EP MMAR_1240|M.marinum_M SAHKHDLAELVTIEVGKTGSEALGEVQEMIDICEFAVGLSRQLYGL--TI MUL_2647|M.ulcerans_Agy99 SAHKHDLAELVTIEVGKTGSEALGEVQEMIDICEFAVGLSRQLYGL--TI Mflv_2172|M.gilvum_PYR-GCK EARRATLLEVMAAETGKTLDQGDPEVSEAIDFANYYASLAEKLDRVDG-- . . : *:. .. : . . : MSMEG_6687|M.smegmatis_MC2_155 SSPRAG--EQILVTRKPLGVVGVITPFNFPIAIPAWKIAPALVYGNTVVW Mvan_1856|M.vanbaalenii_PYR-1 SSPRPG--EQILVTRKPLGVVGVVTPFNFPIAIPAWKIAPALVYGNTVVW MAB_0823|M.abscessus_ATCC_1997 SSPRRG--EHILVTRKPLGVVGVITPFNFPIAIPAWKIAPALVYGNAVLW MAV_2521|M.avium_104 EGAGPG--IDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVL TH_2909|M.thermoresistible__bu EGAGPG--IDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFIL Mb2883c|M.bovis_AF2122/97 QIPVAG--GVDVTFNEPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLV Rv2858c|M.tuberculosis_H37Rv QIPVAG--GVDVTFNEPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLV MLBr_02573|M.leprae_Br4923 AEAAAVGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLL MMAR_1240|M.marinum_M ASERPG--HRLMETWHPLGVVGVITAFNFPVAVWAWNTAVALVCGDTVLW MUL_2647|M.ulcerans_Agy99 ASERPG--HRLMETWHPLGVVGVITAFNFPVAVWAWNTAVALVCGDTVLW Mflv_2172|M.gilvum_PYR-GCK ------------AIARPVGLTVVTPPWNFPVAIPAGSTLAALAAGSAVVI .*:*:. .:*** ** *.. : MSMEG_6687|M.smegmatis_MC2_155 KPASTVPVLAIR----FAQALTEAGLPAGALNLVIG-DSETGTAIVDHPR Mvan_1856|M.vanbaalenii_PYR-1 KPASTVPLLALR----FAEALTDAGLPPGVLNLVVG-GADIGDAIVNHPG MAB_0823|M.abscessus_ATCC_1997 KPASTVPLLAMR----LAQAFDAAGLPPGVLNLVVG-DTGVGDAMVNDSR MAV_2521|M.avium_104 KPSERDPSVPVR----LAELFVEAGLPPGVFQVVHG-DKEAVDAILNHPD TH_2909|M.thermoresistible__bu KPSERDPSVPVR----LAELFLQAGLPSGLFQVVHG-DKEAVDAILEHPT Mb2883c|M.bovis_AF2122/97 KPAELTPLTTMR----LGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPD Rv2858c|M.tuberculosis_H37Rv KPAELTPLTTMR----LGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPD MLBr_02573|M.leprae_Br4923 KHASNVPQCALY----LADVIARGGFPEDCFQTLLI-SANGVEAILRDPR MMAR_1240|M.marinum_M KPSELAPLTALACQALLTRAAADVGAPPSVGAVVLG-GAELGEQLVDDPR MUL_2647|M.ulcerans_Agy99 KPSELAPLTALACQALLTRAAADVGAPPSVGAVVLG-GAELGEQLVDDPR Mflv_2172|M.gilvum_PYR-GCK KPTTQARRCGSV----MVEALWDAGIGRDTLQLVHLDEGELGARLISDAR * : : * . : :: .. MSMEG_6687|M.smegmatis_MC2_155 IDGLTFTGSTAVGRRLASVAATCGIPMQAEMGGKNAAVVLDDADLDVAVE Mvan_1856|M.vanbaalenii_PYR-1 IDGITFTGSTGVGRRIAAAAAARGVPAQAEMGGKNAAVVLDDADLDLAVE MAB_0823|M.abscessus_ATCC_1997 VDALTFTGSTGVGRRIAAAGAARGIPVQAEMGGKNAAVVLDDADVDLAVE MAV_2521|M.avium_104 IQAVGFVGSSDIAQYIYAGAAATGKRAQCFGGAKNHMIVMPDADLDQAVD TH_2909|M.thermoresistible__bu IQAVGFVGSSDIAQYIYAGATAHGKRAQCFGGAKNHMIVMPDADLDQAVD Mb2883c|M.bovis_AF2122/97 IRKIVFTGSTEVGKRVMAGAAAQVKRVTLELGGKSANIVFHDCDLERAAT Rv2858c|M.tuberculosis_H37Rv IRKIVFTGSTEVGKRVMAGAAAQVKRVTLELGGKSANIVFHDCDLERAAT MLBr_02573|M.leprae_Br4923 VAAATLTGSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVA MMAR_1240|M.marinum_M IALLSATGSVRMGQQVGPRVARRFGRVLLELGGNNAVIVTPSADLDLAVR MUL_2647|M.ulcerans_Agy99 IALLSATGSVRMGQQVGPRVARRFGRVLLELGGNNAVIVTPSADLDLAVR Mflv_2172|M.gilvum_PYR-GCK VDRVILTG--AFDTAALFRSFRPDLVLLAETSGKNAIVVTPHADVDLAVK : .* .... :* .*:: *. MSMEG_6687|M.smegmatis_MC2_155 QVMLGAFRSTGQKCTATSRLIVT--DGIADKFTEALVERARALRVGDPTD Mvan_1856|M.vanbaalenii_PYR-1 QVMLGAFRSTGQKCTATSRLIVT--AGIADAFSEALLAQARALRVGDPVD MAB_0823|M.abscessus_ATCC_1997 QVLLGAFRSTGQKCTATSRLVLT--EGIADAFLSLLKDRADALVVGDPTA MAV_2521|M.avium_104 ALIGAGYGSAGERCMAISVAVPVG-DQTADRLRARLIERVNNLRVGHSLD TH_2909|M.thermoresistible__bu ALIGAGYGSAGERCMAISVAVPVG-DEIADRLRARLIERVANLRVGHSLD Mb2883c|M.bovis_AF2122/97 TAPAGVFDNAGQDCCARSRILVQ--RSVYDRFMELLEPAVHSIVVGDPGS Rv2858c|M.tuberculosis_H37Rv TAPAGVFDNAGQDCCARSRILVQ--RSVYDRFMELLEPAVHSIVVGDPGS MLBr_02573|M.leprae_Br4923 TAVTGRVQNNGQSCIAAKRFIAH--ADIYDEFVEKFVARMETLRVGDPTD MMAR_1240|M.marinum_M GIVFAAAGTAGQRCTSLRRLIVH--SSVADDVVARVVAACRTLPVGDPCD MUL_2647|M.ulcerans_Agy99 GIVFAAAGTAGQRCTSLRRLIVH--SSVADDVVARVVAACRTLPVGDPCD Mflv_2172|M.gilvum_PYR-GCK DLVYSAFGHAGQKCSAASLGILVGSVARSARFRDQLVDAVTSLNVGYPTD . *: * : : . . : ** . MSMEG_6687|M.smegmatis_MC2_155 DATEMGPVITDTSRASILAGIDTAVAQGATVLAGGR-------PYTEGPL Mvan_1856|M.vanbaalenii_PYR-1 DATQMGPVVSDSAQQSITAGIDTAVTQGATVLTGGR-------PYQDGAL MAB_0823|M.abscessus_ATCC_1997 DDTQMGPVVSESAFGTITAGIGGAVAQGAVTLAGGH-------GYGDGPL MAV_2521|M.avium_104 PKADYGPLVTEAALARVRDYIAQGVDAGAELVIDGRERASDDLAFGDANL TH_2909|M.thermoresistible__bu PKADYGPLVTEAALQRVRDYIGQGVEAGAELLVDGRERGSDDLQFGDDSL Mb2883c|M.bovis_AF2122/97 RATEMGPLVSRAHRDKVAGYVPDDAPVAFR---------------GTAPA Rv2858c|M.tuberculosis_H37Rv RATEMGPLVSRAHRDKVAGYVPDDAPVAFR---------------GTAPA MLBr_02573|M.leprae_Br4923 PDTDVGPLATESGRAQVEQQVDAAAAAGAVIRCGGK-----------RPD MMAR_1240|M.marinum_M PATLIGPLIHETAYRDMLGALDQARAEGGEVIDPNP---------RRDGP MUL_2647|M.ulcerans_Agy99 PATLIGPLIHETAYRDMLGALDQARAEGGEVIDPNP---------RRDGP Mflv_2172|M.gilvum_PYR-GCK PTVQMGPVIEPADGKLLRALTTLGPGEKWLVAPRQLD------------- . **: : : MSMEG_6687|M.smegmatis_MC2_155 AEGYFIAPTVLELDGSPAKVWSEELFGPVLAVRRAADADEAFELANDSEF Mvan_1856|M.vanbaalenii_PYR-1 AEGYFVAPTVVELGAAPVDVWTDELFGPVLAIRRATDAEEAFALANDSEF MAB_0823|M.abscessus_ATCC_1997 AAGYFIAPTIMELGMGAVDLWTEELFGPVLAVRRAADTEEAFRLANDSEY MAV_2521|M.avium_104 EGGFFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRAHDYEEALALPSQHEY TH_2909|M.thermoresistible__bu EGGYFIGPTLFDRVTTDMSIYRDEIFGPVLCMVRAKNYEEALALPSEHEY Mb2883c|M.bovis_AF2122/97 GRGFWFPPTVLTPKRGDR-TVTDEIFGPVVVVLTFDDEADAISLANDTAY Rv2858c|M.tuberculosis_H37Rv GRGFWFPPTVLTPKRGDR-TVTDEIFGPVVVVLTFDDEADAISLANDTAY MLBr_02573|M.leprae_Br4923 RPGWFYPPTVITDITKDMALYTDEVFGPVASVYCATNIDDAIEIANATPF MMAR_1240|M.marinum_M AGGYYVAPAVVR-MPAQTAIVATETFAPILYVLTYDDLDDAIALNNAVPQ MUL_2647|M.ulcerans_Agy99 AGGYYVAPAVVR-MPAQTAIVATETFAPILYVLTYDDLDDAIALNNAVPQ Mflv_2172|M.gilvum_PYR-GCK DSGRLWSPGVRTGVRRGSEFHLTEYFGPVLGLMEARDLDEAIAMQNQVDY * * : * *.*: : : :*: : . MSMEG_6687|M.smegmatis_MC2_155 GLSAAIFTQDVTRVLQAMEQIDVGVLHVNSESAGADPHVP-FGGDKKSGL Mvan_1856|M.vanbaalenii_PYR-1 GLSAAVFTQDMTRALQAVERIDVGVLHVNSESAGADPHVP-FGGAKKSGL MAB_0823|M.abscessus_ATCC_1997 GLSAAIFTKDLTRALSAVDHVDVGILHVNSESAGADPHVP-FGGAKKSGL MAV_2521|M.avium_104 GNGVAVFTGDGDAARDFVSRVQVGMVGVNVPIPVPVAYHT-FGGWKRSGF TH_2909|M.thermoresistible__bu GNGVAIFTRDGDTARDFVSRVQCGMVGVNVPIPVPVAYHT-FGGWKRSGF Mb2883c|M.bovis_AF2122/97 GLSGSIWTDDLSRALRVARAVESGNLSVNSHSS-VRFNTP-FGGFKQSGV Rv2858c|M.tuberculosis_H37Rv GLSGSIWTDDLSRALRVARAVESGNLSVNSHSS-VRFNTP-FGGFKQSGV MLBr_02573|M.leprae_Br4923 GLGSNAWTQNESEQRHFIDNIVAGQVFIN-GMTVSYPELP-FGGIKRSGY MMAR_1240|M.marinum_M GLSSAIFTNDLREAERFLAASDCGIANVNIGTSGAEIGGA-FGGEKQTGG MUL_2647|M.ulcerans_Agy99 GLSSAFFTNDLREAERFLAASDCGIANVNIGTSGAEIGGA-FGGEKQTGG Mflv_2172|M.gilvum_PYR-GCK GLTAGLHSLDRHEVERWIDRVEAGNAYVNRSTVGAVVARQPFGGWKKSAV * : : * :* *** *::. MSMEG_6687|M.smegmatis_MC2_155 GPK------------------------EQGAAARDFFTHTTTVYLRGGRP Mvan_1856|M.vanbaalenii_PYR-1 GPK------------------------EQGGAAREFFTHTTTVYLRGGRA MAB_0823|M.abscessus_ATCC_1997 GPK------------------------EQGRAAREFFTHTTTVYLRGEEA MAV_2521|M.avium_104 GDLN-----------------------QHGPASITFYTKTKTVTQRWPSG TH_2909|M.thermoresistible__bu GDLN-----------------------QHGPHSILFYTKTKTVTQRWPSG Mb2883c|M.bovis_AF2122/97 GRE-------------------------LGPDAPLQFTETKNVFIAVGEE Rv2858c|M.tuberculosis_H37Rv GRE-------------------------LGPDAPLQFTETKNVFIAVGEE MLBr_02573|M.leprae_Br4923 GRE-------------------------LSTHGIREFCNIKTVWIA---- MMAR_1240|M.marinum_M GRE-------------------------SGSDAWKAYMRRATNTINYSTE MUL_2647|M.ulcerans_Agy99 GRE-------------------------SGSDAWKAYMRRATNTINYSTE Mflv_2172|M.gilvum_PYR-GCK GAGAKAGGPNYLIGLTDWESAPAQQAGRLSPAMREFLSAAGRLDLSAEDR * . MSMEG_6687|M.smegmatis_MC2_155 GV------------------------------------------------ Mvan_1856|M.vanbaalenii_PYR-1 GS------------------------------------------------ MAB_0823|M.abscessus_ATCC_1997 M------------------------------------------------- MAV_2521|M.avium_104 IKDGAEFSIPTMI------------------------------------- TH_2909|M.thermoresistible__bu IKDGAEFSIPTMK------------------------------------- Mb2883c|M.bovis_AF2122/97 M------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv M------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M LPLAQGVQFG---------------------------------------- MUL_2647|M.ulcerans_Agy99 LPLAQSVQFG---------------------------------------- Mflv_2172|M.gilvum_PYR-GCK EFLGRSARSDALAWEQEFGIARDVAGLTAEKNVLRYRPVPVTVRAEDGHT MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK ASLLRVVAAGLLAGAAITVSTPAPPASAVADLLHMRGVTLRVDDAEHWRK MSMEG_6687|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1856|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0823|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_2521|M.avium_104 -------------------------------------------------- TH_2909|M.thermoresistible__bu -------------------------------------------------- Mb2883c|M.bovis_AF2122/97 -------------------------------------------------- Rv2858c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02573|M.leprae_Br4923 -------------------------------------------------- MMAR_1240|M.marinum_M -------------------------------------------------- MUL_2647|M.ulcerans_Agy99 -------------------------------------------------- Mflv_2172|M.gilvum_PYR-GCK LLRGNAPARVRLIGGSREAFAGAGEGRADVALYAQPVVEAGRIELLTFLR MSMEG_6687|M.smegmatis_MC2_155 ----------------------- Mvan_1856|M.vanbaalenii_PYR-1 ----------------------- MAB_0823|M.abscessus_ATCC_1997 ----------------------- MAV_2521|M.avium_104 ----------------------- TH_2909|M.thermoresistible__bu ----------------------- Mb2883c|M.bovis_AF2122/97 ----------------------- Rv2858c|M.tuberculosis_H37Rv ----------------------- MLBr_02573|M.leprae_Br4923 ----------------------- MMAR_1240|M.marinum_M ----------------------- MUL_2647|M.ulcerans_Agy99 ----------------------- Mflv_2172|M.gilvum_PYR-GCK EQAVAVTAHRFGSPTTLADGLFA