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KRWAVNPWRRSGVPARVGWLLAGGYGTAALLVLLSSVRGWRGPYGTRPVDDLVMFVCLAVAAMCAARAAR AASGRRRYGWLALTTALLGWAVGEVIWAVYDVRPEFEHAAHPAAAEMVLLLFPVGAMTSLVLLSQLSRHS PRRLLLDGLIVATSLFVISWVFVVEAQLREHTGTQVATLAEVFNDIVLMTTAILTLSRARPGDRPSRSLL ACGIATISVTDIAMVFYTGIGSYHTDDIGDLARVAGVGTLALAGLASVYEQPAPGSPDEIEFRTRLWLPY LPLILAAAVGWGHAAGKAIHEPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREAFRDNLTGLANRALF VHRLEQAVARRHPDGTPIAVLCLDLDNFKAVNDALGHPAGDELLVRVAERLTAALGDSGTIARLGGDEFA AVIEASVDESQAAAHRILEAFTGAILIDGIPITVRPSIGFTVCTGASTCTVDQLLRHADLAMYAAKREGG QCIRSFMPDLPLPYAFPPPPGSAAPTAVAAVAAGGNGAAPASPPQVATAATSSPSPHDAARRPPRGIRAA LGMLAIGVVAFSVSSVAHPDAGHGIFSATALYSALNAVAAGLIALRACRIPADRWAWALIAAGMACSAVG DVVYAVWVPDGRSPSVADPEYLAYYPFVYAGLLLLMRARLKRLPIAVQLDSVVCALTLAAVAAALTAGPL HQAAVHAPKTVWVGLAYPWCDLMLLALAAGMLPILGWRNEIRWALLVAGLVLFAVADGAYLFQTAAGSYR VGSLLDVCWPASSVLIAMASWAPPPATATQARRRFSPYVTPVASTIVALGVIVLAHHSRSAATLAALSLV VGAGRFSLTFRDVSLLHSHDRHAMTDELTALPNRRQLVTALQGLPASASPGAGSMPSRANPRRALLLLSL SDFHEITESIGRQFGDELLCHIANRLAGSVRRDDLLARVGDDQFAVLLADGANLTAASAQAGRLLEALSE PIALDPITVQVDGRIAIALCPDHCDHPRELLSRAETALAHAKSARSKIAVYDSAFEAHRDNDTNLIEELR TALFDTDELKLHYQPKIDGRDGSIHSVEAVLRWQHPTRGTLLPEEFLPVAERAGLMRKISNRTLSMALQQ VRSWREEGLRLTVAVNLSTTNLLDIELVGTVERLLANYDLPADALILEITESALVDSVRSRNTVTALQRL GIRISIDDYGTGWSSLARLQEVSVDELKLDRIFVARLAHDARSVAIVRSTVALADNLGADLVAEGVENED TLDALRRYGCNITQGFVHTPPLPPDELRAWIASHAPDPSQSRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1410 | - | - | 100% (1304) | cyclic diguanylate phosphodiesterase domain-containing protein |
| M. avium 104 | MAV_3132 | - | 8e-56 | 34.25% (435) | GGDEF domain-containing protein |
| M. avium 104 | MAV_1132 | - | 1e-52 | 31.11% (434) | cyclic diguanylate phosphodiesterase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1389c | - | 6e-55 | 32.27% (440) | hypothetical protein Mb1389c |
| M. gilvum PYR-GCK | Mflv_3478 | - | 6e-81 | 29.54% (738) | diguanylate cyclase/phosphodiesterase |
| M. tuberculosis H37Rv | Rv1354c | - | 6e-55 | 32.27% (440) | hypothetical protein Rv1354c |
| M. leprae Br4923 | MLBr_01750 | - | 2e-58 | 32.96% (449) | hypothetical protein MLBr_01750 |
| M. abscessus ATCC 19977 | MAB_3940c | - | 4e-15 | 33.00% (200) | hypothetical protein MAB_3940c |
| M. marinum M | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2196 | - | 4e-60 | 34.11% (431) | sensory box/response regulator |
| M. thermoresistible (build 8) | TH_0811 | - | 2e-62 | 34.87% (433) | sensory box/response regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4640 | - | 1e-76 | 30.10% (721) | diguanylate cyclase/phosphodiesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3478|M.gilvum_PYR-GCK ----------MGSGRWRLVTRLPIALPAAACIGLAVLLAVDRGGSAVPLI
Mvan_4640|M.vanbaalenii_PYR-1 ----------MSGGRPRLLG-SCIAVPVGLTVALAVVLAVGGDGAWVPVL
MAV_1410|M.avium_104 MKRWAVNPWRRSGVPARVGWLLAGGYGTAALLVLLSSVRGWRGPYGTRPV
MSMEG_2196|M.smegmatis_MC2_155 ------------------------------------------------MS
TH_0811|M.thermoresistible__bu ------------------------------------------------VS
MLBr_01750|M.leprae_Br4923 ------------------------------------------------MT
Mb1389c|M.bovis_AF2122/97 -------------------------------------------MCNDTAT
Rv1354c|M.tuberculosis_H37Rv -------------------------------------------MCNDTAT
MAB_3940c|M.abscessus_ATCC_199 ----------------MIVSYIRSTAWMGFLRQWWTEPVPTGWLRGFLHA
Mflv_3478|M.gilvum_PYR-GCK DDITILGLSTYATVCAVLAALSAAGRMRTAWAIMAAALGSWAVADLIWLL
Mvan_4640|M.vanbaalenii_PYR-1 DDVIIVALSSCATVCAVLAAKSAEGRQRRAWATMAAAMGAWAVADLIWLV
MAV_1410|M.avium_104 DDLVMFVCLAVAAMCAARAARAASGRRRYGWLALTTALLGWAVGEVIWAV
MSMEG_2196|M.smegmatis_MC2_155 ESLDVLVTSVATQLMAVEAATSVSVSQQ----------------------
TH_0811|M.thermoresistible__bu TELDLLVTGVATKLMAADAATARDVSRR----------------------
MLBr_01750|M.leprae_Br4923 RSLDELVTRVASKLMAATAATAVTISEG----------------------
Mb1389c|M.bovis_AF2122/97 PQLEELVTTVANQLMTVDAATSAEVSQR----------------------
Rv1354c|M.tuberculosis_H37Rv PQLEELVTTVANQLMTVDAATSAEVSQR----------------------
MAB_3940c|M.abscessus_ATCC_199 RKLDRTVRNLIGGYALIFAAICIAVQFS----------------------
.: ** .
Mflv_3478|M.gilvum_PYR-GCK CDY--VLHIEPFPSPADLFYLAFSVLAVPGLLAMAPFDALARRQAKIRIT
Mvan_4640|M.vanbaalenii_PYR-1 CEY--VLRVEPFPSPADFFYLAFSVLVVPAVLGMAQFDAWSRRQATLRIA
MAV_1410|M.avium_104 YDVRPEFEHAAHPAAAEMVLLLFPVGAMTSLVLLSQLSRHSPR----RLL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK LDGITVALCVFLLAWLLALNTVYETYRDDTLTLALALLYPAADIVILAVS
Mvan_4640|M.vanbaalenii_PYR-1 LDGVTVALCSFLLAWIFALDRVYEAYRDDKLALGLAFFYPVADMVILAVA
MAV_1410|M.avium_104 LDGLIVATSLFVISWVFVVEAQLREHTGTQVATLAEVFN---DIVLMTTA
MSMEG_2196|M.smegmatis_MC2_155 -------VLAELVSFFDVDVSFLRHNDHRAHATRLVAEWPPRPVDAATDP
TH_0811|M.thermoresistible__bu -------VLADLVRAFELDFSFLRHNDHEIRASKLIAEWPVRENVPDPDP
MLBr_01750|M.leprae_Br4923 -------VLAILVEHFGVDVSFLRHNNHDIHETKLIVEWPPRDYVPDPDP
Mb1389c|M.bovis_AF2122/97 -------VLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDP
Rv1354c|M.tuberculosis_H37Rv -------VLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDP
MAB_3940c|M.abscessus_ATCC_199 ------------DTGPRSMIGRVIVGLCAVGSLGWALRWAVGPWPSLREA
.
Mflv_3478|M.gilvum_PYR-GCK VAVLARVDTRQRATLGLLVVAFAVMAVTDSTFAYGVAEDSYTTGSIIDVG
Mvan_4640|M.vanbaalenii_PYR-1 VAVLARVDAAHRAVPALLVFGFAVMTLTDSAFAYGVAVDSYRTGSFIDLG
MAV_1410|M.avium_104 ILTLSRARPGDRPSRSLLACGIATISVTDIAMVFYTGIGSYHTDDIGDLA
MSMEG_2196|M.smegmatis_MC2_155 IAVVHFADADP---------VFAMAEHLKEPAVFRPEPLYDDYQRTIEAG
TH_0811|M.thermoresistible__bu IGVVHFEGADP---------VFALAEHAKEIHIFRPEPATDEFQRLIEES
MLBr_01750|M.leprae_Br4923 IGVVYFADADP---------VFAMAEYLKEPAVLRPEPANADYQRRIEEG
Mb1389c|M.bovis_AF2122/97 LRLIYFADADP---------VFALCEHAKEPLVFRPEPATEDYQRLIEEA
Rv1354c|M.tuberculosis_H37Rv LRLIYFADADP---------VFALCEHAKEPLVFRPEPATEDYQRLIEEA
MAB_3940c|M.abscessus_ATCC_199 VAFVAFADIGI---------AVACWQDSDPLAGLVGTVLFTPVGAYVSFF
: : .* . .
Mflv_3478|M.gilvum_PYR-GCK WAVSSAMIGMAALVSRRTPPPRPATLSVPSGTALWAPYLPLLVAGIVVP-
Mvan_4640|M.vanbaalenii_PYR-1 WAVALVAICAAAQLSRENPQFRMPIVLVPSNTALWAPYVPLLLAGTIGP-
MAV_1410|M.avium_104 RVAGVGTLALAGLASVYEQPAPGSPDEIEFRTRLWLPYLPLILAAAVGWG
MSMEG_2196|M.smegmatis_MC2_155 RHIPATSMACVPLLSG--DVTTGVLGFVKFGDREWL--------------
TH_0811|M.thermoresistible__bu SGVPASTVAAVPLVSG--EITTGVLGFVKYGDRQWH--------------
MLBr_01750|M.leprae_Br4923 ASVPAVSLACVPLLSG--EITTGVLGFVKYGDREWH--------------
Mb1389c|M.bovis_AF2122/97 RGVPVTSAAAVPLVSG--EITTGLLGFIKFGDRKWH--------------
Rv1354c|M.tuberculosis_H37Rv RGVPVTSAAAVPLVSG--EITTGLLGFIKFGDRKWH--------------
MAB_3940c|M.abscessus_ATCC_199 LANRLLVAHVAWCAPMIIALSSRLFAEGTVGAAMTA--------------
. .
Mflv_3478|M.gilvum_PYR-GCK ---PLVTTGLERYVAPAIVITVCLRQFFAAWENRQWLKAAAERSLRDPLT
Mvan_4640|M.vanbaalenii_PYR-1 ---PLVMSGLEQLVVPVIVVAVCLRQVVAAWENRQLLRAAAEQALRDPLT
MAV_1410|M.avium_104 HAAGKAIHEPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREAFRDNLT
MSMEG_2196|M.smegmatis_MC2_155 ----------PAELNALKAIASLFAQVQARIEAEERLRYLADH---DHLT
TH_0811|M.thermoresistible__bu ----------PDELNALKAIASLFAQVQARVEAEERLRYLAEH---DDLT
MLBr_01750|M.leprae_Br4923 ----------DDELRALQAIATLFAQLQARIVAEEQLRYLAEH---DDLT
Mb1389c|M.bovis_AF2122/97 ----------EAELNALMTIATLFAQVQARVAAEARLRYLADH---DDLT
Rv1354c|M.tuberculosis_H37Rv ----------EAELNALMTIATLFAQVQARVAAEARLRYLADH---DDLT
MAB_3940c|M.abscessus_ATCC_199 ----------LVKVTSMLLVVVLIPAVIQFGIAVVRWDALAAQ--RDPLT
. . * . * **
Mflv_3478|M.gilvum_PYR-GCK GLANGTLFHDRLRHAMMLHARGD-----RSVMVVSLDLDDFAFVNDNLGH
Mvan_4640|M.vanbaalenii_PYR-1 ELANQRLFYDRLAHALTLSSREG-----HSVAVVSLDLDDFKLVNDSVGH
MAV_1410|M.avium_104 GLANRALFVHRLEQAVARRHPDG-----TPIAVLCLDLDNFKAVNDALGH
MSMEG_2196|M.smegmatis_MC2_155 GLYNRRALMAHLEARLAPGQPG-------PVAVMFFDLDRLKAINDYLGH
TH_0811|M.thermoresistible__bu GLHNRRALLAHLDARLAAGQPG-------PVSALYFDLDRLKAVNDYLGH
MLBr_01750|M.leprae_Br4923 GLLNRRALIAHLDERLADGQRG-------PVTLLFLGLDRLKAVNDYLGH
Mb1389c|M.bovis_AF2122/97 GLHNRRALLQHLDQRLAPGQPG-------PVAALFLDLDRLKAINDYLGH
Rv1354c|M.tuberculosis_H37Rv GLHNRRALLQHLDQRLAPGQPG-------PVAALFLDLDRLKAINDYLGH
MAB_3940c|M.abscessus_ATCC_199 GLLNRRGIYAEWQRLYGELRREQPLDGDQVTAAAIVDIDRFKSINDRYGH
* * : . ..:* : :** **
Mflv_3478|M.gilvum_PYR-GCK PAADRLLVHAGRRIAACVRPGDTVGRVAGDEFALLLEG--DVHDSQRVLQ
Mvan_4640|M.vanbaalenii_PYR-1 PEADSLLVRVGQRIADCVRAGDTVARIQGDEFALLLEG--EHDDSKLIAE
MAV_1410|M.avium_104 PAGDELLVRVAERLTAALGDSGTIARLGGDEFAAVIEA--SVDESQAAAH
MSMEG_2196|M.smegmatis_MC2_155 TAGDAFISILAQRLQRGDDAPKLIARLGGDEFVVVPDDPMSLDEATALAY
TH_0811|M.thermoresistible__bu TVGDWFIRVLAERLREGAGPDDLIARLGGDEFVVVPSGPVDADAALELAN
MLBr_01750|M.leprae_Br4923 NAGDRLIEVFADRLREAAESLTVIARFGGDEFVVVPAESVSVDVAESFAH
Mb1389c|M.bovis_AF2122/97 AAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAE
Rv1354c|M.tuberculosis_H37Rv AAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAE
MAB_3940c|M.abscessus_ATCC_199 GTGDRVLIDVAHALTCGTTGTSVVGRSGGEEFLVVTVCPASAVAEFATRL
.* .: . : :.* *:** : .
Mflv_3478|M.gilvum_PYR-GCK RVVATFDEPFDVDGEPVTIRCSVGVAVAFADEPEVTPETMLRRADIAVRV
Mvan_4640|M.vanbaalenii_PYR-1 RVVDAFDEPFVLHGEHILLRPSVGVAAASPGEAEVAPETMVMRAETAMNV
MAV_1410|M.avium_104 RILEAFTGAILIDGIPITVRPSIGFTVCTG-ASTCTVDQLLRHADLAMYA
MSMEG_2196|M.smegmatis_MC2_155 RLQSVLRERVTVDGEMLTRTVSIGIAQGIP--GKDSTSDVLNRADHAVLT
TH_0811|M.thermoresistible__bu RLRSRLQQQVCVDGEMLTRTASIGVAQGTP--GRDTTSDLLRRADQAVLT
MLBr_01750|M.leprae_Br4923 RLQTRLQKQVVIDGEILTRTVSIGVATGLP--GRDTTSDLLRWADHAALS
Mb1389c|M.bovis_AF2122/97 RLRDQLKDHVAIGGEVLTRTVSIGVASGTP--GQHTPSDLLRRADQAALA
Rv1354c|M.tuberculosis_H37Rv RLRDQLKDHVAIGGEVLTRTVSIGVASGTP--GQHTPSDLLRRADQAALA
MAB_3940c|M.abscessus_ATCC_199 RQAVTASMPAGIAVTASVGVAAQAVSRVVSATSQEAIEVLTACADRAMYE
* : : ..: : . : *: *
Mflv_3478|M.gilvum_PYR-GCK AKR----------SHFPRVRFFEDDIEDDFDDDMATTDSDAAQGGDRSTD
Mvan_4640|M.vanbaalenii_PYR-1 AKR----------SRSSRVHVFDATLESAAPDVVAP---------ERGSP
MAV_1410|M.avium_104 AKREGGQCIRSFMPDLPLPYAFPPPPGSAAPTAVAAVAAGGNGAAPASPP
MSMEG_2196|M.smegmatis_MC2_155 AKG----------SGGNRVAVFSDAMA-----------------------
TH_0811|M.thermoresistible__bu AKS----------AGGNQITVFTDDMS-----------------------
MLBr_01750|M.leprae_Br4923 AK-----------SDGSKVVVLDHGIS-----------------------
Mb1389c|M.bovis_AF2122/97 AKH----------AGGDSVAIFTADMS-----------------------
Rv1354c|M.tuberculosis_H37Rv AKH----------AGGDSVAIFTADMS-----------------------
MAB_3940c|M.abscessus_ATCC_199 AKH----------DGGDQSRILHADDD-----------------------
** :
Mflv_3478|M.gilvum_PYR-GCK RVALTGAAKVRLLSELRR--------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 QNWPDGAAKVRLLGELRR--------------------------------
MAV_1410|M.avium_104 QVATAATSSPSPHDAARRPPRGIRAALGMLAIGVVAFSVSSVAHPDAGHG
MSMEG_2196|M.smegmatis_MC2_155 ---MEIDFRNDIELHLQS--------------------------------
TH_0811|M.thermoresistible__bu ---LEAEFRNDIELHLQS--------------------------------
MLBr_01750|M.leprae_Br4923 ---AQHTLRTEVELHLAG--------------------------------
Mb1389c|M.bovis_AF2122/97 ---VSGELRNDIELHLRR--------------------------------
Rv1354c|M.tuberculosis_H37Rv ---VSGELRNDIELHLRR--------------------------------
MAB_3940c|M.abscessus_ATCC_199 ---SEGRYLWRSGA------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 IFSATALYSALNAVAAGLIALRACRIPADRWAWALIAAGMACSAVGDVVY
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 AVWVPDGRSPSVADPEYLAYYPFVYAGLLLLMRARLKRLPIAVQLDSVVC
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 ALTLAAVAAALTAGPLHQAAVHAPKTVWVGLAYPWCDLMLLALAAGMLPI
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 LGWRNEIRWALLVAGLVLFAVADGAYLFQTAAGSYRVGSLLDVCWPASSV
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 LIAMASWAPPPATATQARRRFSPYVTPVASTIVALGVIVLAHHSRSAATL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 AALSLVVGAGRFSLTFRDVSLLHSHDRHAMTDELTALPNRRQLVTALQGL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 PASASPGAGSMPSRANPRRALLLLSLSDFHEITESIGRQFGDELLCHIAN
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 RLAGSVRRDDLLARVGDDQFAVLLADGANLTAASAQAGRLLEALSEPIAL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 DPITVQVDGRIAIALCPDHCDHPRELLSRAETALAHAKSARSKIAVYDSA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK ------------------AVDQGDLELAYQPKVDLVSGQVVGVEALLRWP
Mvan_4640|M.vanbaalenii_PYR-1 ------------------AIDNGEFHMVYQPIVDLRSGFIVGVEALLRWP
MAV_1410|M.avium_104 FEAHRDNDTNLIEELRTALFDTDELKLHYQPKIDGRDGSIHSVEAVLRWQ
MSMEG_2196|M.smegmatis_MC2_155 ------------------VIEGGALVLHYLPEIDMRTGEVLAAEALVRWE
TH_0811|M.thermoresistible__bu ------------------VIQDEALLLHFLPEVDMRTGEILATEALVRWH
MLBr_01750|M.leprae_Br4923 ------------------MID-TDLVLHYLPEVDMSTGKVLGTEALVRWQ
Mb1389c|M.bovis_AF2122/97 ------------------GIESDALRLVYLPEVDLRTGDIVGTEALVRWQ
Rv1354c|M.tuberculosis_H37Rv ------------------GIESDALRLVYLPEVDLRTGDIVGTEALVRWQ
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK HPELGLLYPGTFMPLVREHKLIRPVTDLVIDKVLDDAARWVGT--GAPIP
Mvan_4640|M.vanbaalenii_PYR-1 HPRLGMLSPDAFLPLVRQHGLMRPVTEVVLDNVLDDAARWMAD--GVPMP
MAV_1410|M.avium_104 HPTRGTLLPEEFLPVAERAGLMRKISNRTLSMALQQVRSWREE--GLRLT
MSMEG_2196|M.smegmatis_MC2_155 HPTRGLLSPDSFIGVAESINLAGELGRWVLRTACAEFSRWRANGVGRNIV
TH_0811|M.thermoresistible__bu HPTRGLLAPDTFIGVAESVNLAGELGRWVMRTACGEFAKWRAEGIGLDAV
MLBr_01750|M.leprae_Br4923 HPTRGLLFPDSFIPVAESINLAGKLGRMVMHSACAEFSRWRSAGVGLDAL
Mb1389c|M.bovis_AF2122/97 HPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDAL
Rv1354c|M.tuberculosis_H37Rv HPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDAL
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK VAVNLFAPSLIDARLPATLRAALERRGLPAELLTVEITEDLVINDLERVT
Mvan_4640|M.vanbaalenii_PYR-1 VAVNLFAPFLRDAQLPSALCQALERRGLPTDLLTVEITEDLVLHDFDVVT
MAV_1410|M.avium_104 VAVNLSTTNLLDIELVGTVERLLANYDLPADALILEITESALVDSVRSRN
MSMEG_2196|M.smegmatis_MC2_155 LRINVSPVQLVTDGFVESVAGIMKEFGLPRGSVCLEITESVVVQDIETTR
TH_0811|M.thermoresistible__bu LRINVSPVQLVTDGFVASVADIIDEFGLDGSSVCLEITESVVVQDIKTTR
MLBr_01750|M.leprae_Br4923 LRINVSPVQLVAEGFVDNVAGTLDEFGLDGSMVCLEITENVVVQNIDATR
Mb1389c|M.bovis_AF2122/97 LRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTAR
Rv1354c|M.tuberculosis_H37Rv LRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTAR
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK AVLGQLRDHGIRVSIDDFGSGYSALSYLRDLLIDEIKLDRSFIAAVTTDP
Mvan_4640|M.vanbaalenii_PYR-1 GVLGQLREQGIRVAIDDFGSGFSALSYLRELRIDEIKLDRHFIATVASDP
MAV_1410|M.avium_104 TVT-ALQRLGIRISIDDYGTGWSSLARLQEVSVDELKLDRIFVARLAHDA
MSMEG_2196|M.smegmatis_MC2_155 TTLTGLHNVGVQVAIDDFGTGYSVLSLLKSLPVDTLKIDRSFVAELGSNP
TH_0811|M.thermoresistible__bu ITLEGLNEVGVQVAIDDFGTGYSVLSHLKTLPVDTLKIDKGFVQDLGNSP
MLBr_01750|M.leprae_Br4923 KTLAGLKEVGVHLAIDDFGTGYSVLTHLKSLPVDTIKIDKSFVAELGSNA
Mb1389c|M.bovis_AF2122/97 ATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNT
Rv1354c|M.tuberculosis_H37Rv ATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNT
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK RAAVVVRAIIELTHGLGMTVVAEGIEEAATANWLRDSGCDIGQGFYFGKP
Mvan_4640|M.vanbaalenii_PYR-1 RAAAVVRAVIDLTHDLGSVVVAEGVEEPATAAWLRDRGCDMAQGYYFGKP
MAV_1410|M.avium_104 RSVAIVRSTVALADNLGADLVAEGVENEDTLDALRRYGCNITQGFVHTPP
MSMEG_2196|M.smegmatis_MC2_155 GDLPIVRAVIALAGAFGLQLVAEGVETERAALTLLRHGCYRAQGFLLSKP
TH_0811|M.thermoresistible__bu GDLAIVRAIIALAEAFGLQLVAEGVETEAAALTLLRHGCHRAQGFLLSRP
MLBr_01750|M.leprae_Br4923 SDLAIVRAIMALAKEFELEVVAEGVETAVAAQVLLELGCNRAQGFLLSRP
Mb1389c|M.bovis_AF2122/97 SDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRP
Rv1354c|M.tuberculosis_H37Rv SDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRP
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK VDPADVPSLGR-LAVGPS-----------------
Mvan_4640|M.vanbaalenii_PYR-1 IEAADVPGLVR-MAKDPA-----------------
MAV_1410|M.avium_104 LPPDELRAWIASHAPDPSQSRG-------------
MSMEG_2196|M.smegmatis_MC2_155 ILGSEMQTLLAKGRVPVHFSAAPRM----------
TH_0811|M.thermoresistible__bu IPSNEMRELLARGRIPMRFSATP------------
MLBr_01750|M.leprae_Br4923 VDGAAMESLLAKGVIPMALGTCQSPEPSEHQIHRS
Mb1389c|M.bovis_AF2122/97 VPGEAMRHMLSARRLPPTCIPATDPALS-------
Rv1354c|M.tuberculosis_H37Rv VPGEAMRHMLSARRLPPTCIPATDPALS-------
MAB_3940c|M.abscessus_ATCC_199 -----------------------------------