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MGSGRWRLVTRLPIALPAAACIGLAVLLAVDRGGSAVPLIDDITILGLSTYATVCAVLAALSAAGRMRTA WAIMAAALGSWAVADLIWLLCDYVLHIEPFPSPADLFYLAFSVLAVPGLLAMAPFDALARRQAKIRITLD GITVALCVFLLAWLLALNTVYETYRDDTLTLALALLYPAADIVILAVSVAVLARVDTRQRATLGLLVVAF AVMAVTDSTFAYGVAEDSYTTGSIIDVGWAVSSAMIGMAALVSRRTPPPRPATLSVPSGTALWAPYLPLL VAGIVVPPLVTTGLERYVAPAIVITVCLRQFFAAWENRQWLKAAAERSLRDPLTGLANGTLFHDRLRHAM MLHARGDRSVMVVSLDLDDFAFVNDNLGHPAADRLLVHAGRRIAACVRPGDTVGRVAGDEFALLLEGDVH DSQRVLQRVVATFDEPFDVDGEPVTIRCSVGVAVAFADEPEVTPETMLRRADIAVRVAKRSHFPRVRFFE DDIEDDFDDDMATTDSDAAQGGDRSTDRVALTGAAKVRLLSELRRAVDQGDLELAYQPKVDLVSGQVVGV EALLRWPHPELGLLYPGTFMPLVREHKLIRPVTDLVIDKVLDDAARWVGTGAPIPVAVNLFAPSLIDARL PATLRAALERRGLPAELLTVEITEDLVINDLERVTAVLGQLRDHGIRVSIDDFGSGYSALSYLRDLLIDE IKLDRSFIAAVTTDPRAAVVVRAIIELTHGLGMTVVAEGIEEAATANWLRDSGCDIGQGFYFGKPVDPAD VPSLGRLAVGPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3478 | - | - | 100% (782) | diguanylate cyclase/phosphodiesterase |
| M. gilvum PYR-GCK | Mflv_2073 | - | 0.0 | 54.86% (782) | diguanylate cyclase/phosphodiesterase |
| M. gilvum PYR-GCK | Mflv_2740 | - | 4e-66 | 29.18% (771) | diguanylate cyclase/phosphodiesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1389c | - | 5e-57 | 32.53% (455) | hypothetical protein Mb1389c |
| M. tuberculosis H37Rv | Rv1354c | - | 5e-57 | 32.53% (455) | hypothetical protein Rv1354c |
| M. leprae Br4923 | MLBr_01750 | - | 5e-52 | 31.37% (475) | hypothetical protein MLBr_01750 |
| M. abscessus ATCC 19977 | MAB_1839 | - | 5e-10 | 27.91% (215) | diguanylate cyclase/phosphodiesterase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1410 | - | 3e-81 | 29.54% (738) | cyclic diguanylate phosphodiesterase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2196 | - | 7e-52 | 30.95% (475) | sensory box/response regulator |
| M. thermoresistible (build 8) | TH_0811 | - | 5e-51 | 30.36% (471) | sensory box/response regulator |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4640 | - | 0.0 | 63.30% (782) | diguanylate cyclase/phosphodiesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3478|M.gilvum_PYR-GCK ----------MGSGRWRLVTRLPIALPAAACIGLAVLLAVDRGGSAVPLI
Mvan_4640|M.vanbaalenii_PYR-1 ----------MSGGRPRLLG-SCIAVPVGLTVALAVVLAVGGDGAWVPVL
MAV_1410|M.avium_104 MKRWAVNPWRRSGVPARVGWLLAGGYGTAALLVLLSSVRGWRGPYGTRPV
MSMEG_2196|M.smegmatis_MC2_155 ------------------------------------------------MS
TH_0811|M.thermoresistible__bu ------------------------------------------------VS
MLBr_01750|M.leprae_Br4923 ------------------------------------------------MT
Mb1389c|M.bovis_AF2122/97 -------------------------------------------MCNDTAT
Rv1354c|M.tuberculosis_H37Rv -------------------------------------------MCNDTAT
MAB_1839|M.abscessus_ATCC_1997 ---------------------------------MVTTYPGRNGFGSESNR
Mflv_3478|M.gilvum_PYR-GCK DDITILGLSTYATVCAVLAALSAAGRMRTAWAIMAAALGSWAVADLIWLL
Mvan_4640|M.vanbaalenii_PYR-1 DDVIIVALSSCATVCAVLAAKSAEGRQRRAWATMAAAMGAWAVADLIWLV
MAV_1410|M.avium_104 DDLVMFVCLAVAAMCAARAARAASGRRRYGWLALTTALLGWAVGEVIWAV
MSMEG_2196|M.smegmatis_MC2_155 ESLDVLVTSVATQLMAVEAATSVSVSQQ----------------------
TH_0811|M.thermoresistible__bu TELDLLVTGVATKLMAADAATARDVSRR----------------------
MLBr_01750|M.leprae_Br4923 RSLDELVTRVASKLMAATAATAVTISEG----------------------
Mb1389c|M.bovis_AF2122/97 PQLEELVTTVANQLMTVDAATSAEVSQR----------------------
Rv1354c|M.tuberculosis_H37Rv PQLEELVTTVANQLMTVDAATSAEVSQR----------------------
MAB_1839|M.abscessus_ATCC_1997 CSTGAQVYGANNDILERVGLRRPVSRANAVFITAVG--------------
. : .
Mflv_3478|M.gilvum_PYR-GCK CDY--VLHIEPFPSPADLFYLAFSVLAVPGLLAMAPFDALARRQAKIRIT
Mvan_4640|M.vanbaalenii_PYR-1 CEY--VLRVEPFPSPADFFYLAFSVLVVPAVLGMAQFDAWSRRQATLRIA
MAV_1410|M.avium_104 YDVRPEFEHAAHPAAAEMVLLLFPVGAMTSLVLLSQLSRHSPR----RLL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK LDGITVALCVFLLAWLLALNTVYETYRDDTLTLALALLYPAADIVILAVS
Mvan_4640|M.vanbaalenii_PYR-1 LDGVTVALCSFLLAWIFALDRVYEAYRDDKLALGLAFFYPVADMVILAVA
MAV_1410|M.avium_104 LDGLIVATSLFVISWVFVVEAQLREHTGTQVATLAEVFN---DIVLMTTA
MSMEG_2196|M.smegmatis_MC2_155 -------VLAELVSFFDVDVSFLRHNDHRAHATRLVAEWPPRPVDAATDP
TH_0811|M.thermoresistible__bu -------VLADLVRAFELDFSFLRHNDHEIRASKLIAEWPVRENVPDPDP
MLBr_01750|M.leprae_Br4923 -------VLAILVEHFGVDVSFLRHNNHDIHETKLIVEWPPRDYVPDPDP
Mb1389c|M.bovis_AF2122/97 -------VLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDP
Rv1354c|M.tuberculosis_H37Rv -------VLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDP
MAB_1839|M.abscessus_ATCC_1997 -------AAAILLAATGMSTIPLLCISLSIPAFLWGIRYARARAVTYGES
:: .
Mflv_3478|M.gilvum_PYR-GCK VAVLARVDTRQRATLGLLVVAFAVMAVTDSTFAYGVAEDSYTTGSIIDVG
Mvan_4640|M.vanbaalenii_PYR-1 VAVLARVDAAHRAVPALLVFGFAVMTLTDSAFAYGVAVDSYRTGSFIDLG
MAV_1410|M.avium_104 ILTLSRARPGDRPSRSLLACGIATISVTDIAMVFYTGIGSYHTDDIGDLA
MSMEG_2196|M.smegmatis_MC2_155 IAVVHFADADP---------VFAMAEHLKEPAVFRPEPLYDDYQRTIEAG
TH_0811|M.thermoresistible__bu IGVVHFEGADP---------VFALAEHAKEIHIFRPEPATDEFQRLIEES
MLBr_01750|M.leprae_Br4923 IGVVYFADADP---------VFAMAEYLKEPAVLRPEPANADYQRRIEEG
Mb1389c|M.bovis_AF2122/97 LRLIYFADADP---------VFALCEHAKEPLVFRPEPATEDYQRLIEEA
Rv1354c|M.tuberculosis_H37Rv LRLIYFADADP---------VFALCEHAKEPLVFRPEPATEDYQRLIEEA
MAB_1839|M.abscessus_ATCC_1997 VAYVLYCDVAI---------LIGICVVTTTGVAFVKLAWLLAVSAYVSLV
: : :. .
Mflv_3478|M.gilvum_PYR-GCK WAVSSAMIGMAALVSRRTPPPRPATLSVPSGTALWAPYLPLLVAGIVVP-
Mvan_4640|M.vanbaalenii_PYR-1 WAVALVAICAAAQLSRENPQFRMPIVLVPSNTALWAPYVPLLLAGTIGP-
MAV_1410|M.avium_104 RVAGVGTLALAGLASVYEQPAPGSPDEIEFRTRLWLPYLPLILAAAVGWG
MSMEG_2196|M.smegmatis_MC2_155 RHIPATSMACVPLLSG--DVTTGVLGFVKFGDREWL--------------
TH_0811|M.thermoresistible__bu SGVPASTVAAVPLVSG--EITTGVLGFVKYGDRQWH--------------
MLBr_01750|M.leprae_Br4923 ASVPAVSLACVPLLSG--EITTGVLGFVKYGDREWH--------------
Mb1389c|M.bovis_AF2122/97 RGVPVTSAAAVPLVSG--EITTGLLGFIKFGDRKWH--------------
Rv1354c|M.tuberculosis_H37Rv RGVPVTSAAAVPLVSG--EITTGLLGFIKFGDRKWH--------------
MAB_1839|M.abscessus_ATCC_1997 HGRVAVAMQSLVTTAGTVLAVVGAVSRDEYSAAALA--------------
:
Mflv_3478|M.gilvum_PYR-GCK ---PLVTTGLERYVAPAIVITVCLRQFFAAWENRQWLKAAAERS---LRD
Mvan_4640|M.vanbaalenii_PYR-1 ---PLVMSGLEQLVVPVIVVAVCLRQVVAAWENRQLLRAAAEQA---LRD
MAV_1410|M.avium_104 HAAGKAIHEPMLAALGILVAAVLARQFVVLVDNQNLLSEVAREA---FRD
MSMEG_2196|M.smegmatis_MC2_155 ----------PAELNALKAIASLFAQVQARIEAEERLRYLADH------D
TH_0811|M.thermoresistible__bu ----------PDELNALKAIASLFAQVQARVEAEERLRYLAEH------D
MLBr_01750|M.leprae_Br4923 ----------DDELRALQAIATLFAQLQARIVAEEQLRYLAEH------D
Mb1389c|M.bovis_AF2122/97 ----------EAELNALMTIATLFAQVQARVAAEARLRYLADH------D
Rv1354c|M.tuberculosis_H37Rv ----------EAELNALMTIATLFAQVQARVAAEARLRYLADH------D
MAB_1839|M.abscessus_ATCC_1997 ------------AAVVTMLLANLFAGLVIYVGKAQFSEHADGRDRLARHD
: . . *
Mflv_3478|M.gilvum_PYR-GCK PLTGLANGTLFHDRLRHAMMLHARGDRSVMVVSLDLDDFAFVNDNLGHPA
Mvan_4640|M.vanbaalenii_PYR-1 PLTELANQRLFYDRLAHALTLSSREGHSVAVVSLDLDDFKLVNDSVGHPE
MAV_1410|M.avium_104 NLTGLANRALFVHRLEQAVARRHPDGTPIAVLCLDLDNFKAVNDALGHPA
MSMEG_2196|M.smegmatis_MC2_155 HLTGLYNRRALMAHLEARLAPGQPG--PVAVMFFDLDRLKAINDYLGHTA
TH_0811|M.thermoresistible__bu DLTGLHNRRALLAHLDARLAAGQPG--PVSALYFDLDRLKAVNDYLGHTV
MLBr_01750|M.leprae_Br4923 DLTGLLNRRALIAHLDERLADGQRG--PVTLLFLGLDRLKAVNDYLGHNA
Mb1389c|M.bovis_AF2122/97 DLTGLHNRRALLQHLDQRLAPGQPG--PVAALFLDLDRLKAINDYLGHAA
Rv1354c|M.tuberculosis_H37Rv DLTGLHNRRALLQHLDQRLAPGQPG--PVAALFLDLDRLKAINDYLGHAA
MAB_1839|M.abscessus_ATCC_1997 VLTGLLNRRGLQEAYEATVG--VPG-MHVTVVVVDLNLFKQINDTFGHHV
** * * : : : : ..*: : :** .**
Mflv_3478|M.gilvum_PYR-GCK ADRLLVHAGRRIAACVRPGDTVGRVAGDEFALLLEG--DVHDSQRVLQRV
Mvan_4640|M.vanbaalenii_PYR-1 ADSLLVRVGQRIADCVRAGDTVARIQGDEFALLLEG--EHDDSKLIAERV
MAV_1410|M.avium_104 GDELLVRVAERLTAALGDSGTIARLGGDEFAAVIEA--SVDESQAAAHRI
MSMEG_2196|M.smegmatis_MC2_155 GDAFISILAQRLQRGDDAPKLIARLGGDEFVVVPDDPMSLDEATALAYRL
TH_0811|M.thermoresistible__bu GDWFIRVLAERLREGAGPDDLIARLGGDEFVVVPSGPVDADAALELANRL
MLBr_01750|M.leprae_Br4923 GDRLIEVFADRLREAAESLTVIARFGGDEFVVVPAESVSVDVAESFAHRL
Mb1389c|M.bovis_AF2122/97 GDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERL
Rv1354c|M.tuberculosis_H37Rv GDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERL
MAB_1839|M.abscessus_ATCC_1997 GDQVLQRTAHRLRSVVGPDALLARLGGDEFGIVVVG------DAPPHIDY
.* .: . *: :.*. **** :
Mflv_3478|M.gilvum_PYR-GCK VATFDEPFDVDGEPVTIRCSVGVAVAFADEPEVTPETMLRRADIAVRVAK
Mvan_4640|M.vanbaalenii_PYR-1 VDAFDEPFVLHGEHILLRPSVGVAAASPGEAEVAPETMVMRAETAMNVAK
MAV_1410|M.avium_104 LEAFTGAILIDGIPITVRPSIGFTVCTG-ASTCTVDQLLRHADLAMYAAK
MSMEG_2196|M.smegmatis_MC2_155 QSVLRERVTVDGEMLTRTVSIGIAQGIP--GKDSTSDVLNRADHAVLTAK
TH_0811|M.thermoresistible__bu RSRLQQQVCVDGEMLTRTASIGVAQGTP--GRDTTSDLLRRADQAVLTAK
MLBr_01750|M.leprae_Br4923 QTRLQKQVVIDGEILTRTVSIGVATGLP--GRDTTSDLLRWADHAALSAK
Mb1389c|M.bovis_AF2122/97 RDQLKDHVAIGGEVLTRTVSIGVASGTP--GQHTPSDLLRRADQAALAAK
Rv1354c|M.tuberculosis_H37Rv RDQLKDHVAIGGEVLTRTVSIGVASGTP--GQHTPSDLLRRADQAALAAK
MAB_1839|M.abscessus_ATCC_1997 QRAVEEALNSASEDVPVSASVGVAAAILPESDRTTIHTLGPIVTHLLVEA
. . . : *:*.: : :
Mflv_3478|M.gilvum_PYR-GCK R----------SHFPRVRFFEDDIEDDFDDDMATTDSDAAQGGDRSTDRV
Mvan_4640|M.vanbaalenii_PYR-1 R----------SRSSRVHVFDATLESAAPDVVAP---------ERGSPQN
MAV_1410|M.avium_104 REGGQCIRSFMPDLPLPYAFPPPPGSAAPTAVAAVAAGGNGAAPASPPQV
MSMEG_2196|M.smegmatis_MC2_155 G----------SGGNRVAVFSDAMA-------------------------
TH_0811|M.thermoresistible__bu S----------AGGNQITVFTDDMS-------------------------
MLBr_01750|M.leprae_Br4923 -----------SDGSKVVVLDHGIS-------------------------
Mb1389c|M.bovis_AF2122/97 H----------AGGDSVAIFTADMS-------------------------
Rv1354c|M.tuberculosis_H37Rv H----------AGGDSVAIFTADMS-------------------------
MAB_1839|M.abscessus_ATCC_1997 DG---------------AMYGAKKAG------------------------
Mflv_3478|M.gilvum_PYR-GCK ALTGAAKVRLLSELRR----------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 WPDGAAKVRLLGELRR----------------------------------
MAV_1410|M.avium_104 ATAATSSPSPHDAARRPPRGIRAALGMLAIGVVAFSVSSVAHPDAGHGIF
MSMEG_2196|M.smegmatis_MC2_155 -MEIDFRNDIELHLQS----------------------------------
TH_0811|M.thermoresistible__bu -LEAEFRNDIELHLQS----------------------------------
MLBr_01750|M.leprae_Br4923 -AQHTLRTEVELHLAG----------------------------------
Mb1389c|M.bovis_AF2122/97 -VSGELRNDIELHLRR----------------------------------
Rv1354c|M.tuberculosis_H37Rv -VSGELRNDIELHLRR----------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 SATALYSALNAVAAGLIALRACRIPADRWAWALIAAGMACSAVGDVVYAV
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 WVPDGRSPSVADPEYLAYYPFVYAGLLLLMRARLKRLPIAVQLDSVVCAL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 TLAAVAAALTAGPLHQAAVHAPKTVWVGLAYPWCDLMLLALAAGMLPILG
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 WRNEIRWALLVAGLVLFAVADGAYLFQTAAGSYRVGSLLDVCWPASSVLI
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 AMASWAPPPATATQARRRFSPYVTPVASTIVALGVIVLAHHSRSAATLAA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 LSLVVGAGRFSLTFRDVSLLHSHDRHAMTDELTALPNRRQLVTALQGLPA
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 SASPGAGSMPSRANPRRALLLLSLSDFHEITESIGRQFGDELLCHIANRL
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 AGSVRRDDLLARVGDDQFAVLLADGANLTAASAQAGRLLEALSEPIALDP
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4640|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1410|M.avium_104 ITVQVDGRIAIALCPDHCDHPRELLSRAETALAHAKSARSKIAVYDSAFE
MSMEG_2196|M.smegmatis_MC2_155 --------------------------------------------------
TH_0811|M.thermoresistible__bu --------------------------------------------------
MLBr_01750|M.leprae_Br4923 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 --------------------------------------------------
Rv1354c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK ----------------AVDQGDLELAYQPKVDLVSGQVVGVEALLRWPHP
Mvan_4640|M.vanbaalenii_PYR-1 ----------------AIDNGEFHMVYQPIVDLRSGFIVGVEALLRWPHP
MAV_1410|M.avium_104 AHRDNDTNLIEELRTALFDTDELKLHYQPKIDGRDGSIHSVEAVLRWQHP
MSMEG_2196|M.smegmatis_MC2_155 ----------------VIEGGALVLHYLPEIDMRTGEVLAAEALVRWEHP
TH_0811|M.thermoresistible__bu ----------------VIQDEALLLHFLPEVDMRTGEILATEALVRWHHP
MLBr_01750|M.leprae_Br4923 ----------------MID-TDLVLHYLPEVDMSTGKVLGTEALVRWQHP
Mb1389c|M.bovis_AF2122/97 ----------------GIESDALRLVYLPEVDLRTGDIVGTEALVRWQHP
Rv1354c|M.tuberculosis_H37Rv ----------------GIESDALRLVYLPEVDLRTGDIVGTEALVRWQHP
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK ELGLLYPGTFMPLVREHKLIRPVTDLVIDKVLDDAARWVGT--GAPIPVA
Mvan_4640|M.vanbaalenii_PYR-1 RLGMLSPDAFLPLVRQHGLMRPVTEVVLDNVLDDAARWMAD--GVPMPVA
MAV_1410|M.avium_104 TRGTLLPEEFLPVAERAGLMRKISNRTLSMALQQVRSWREE--GLRLTVA
MSMEG_2196|M.smegmatis_MC2_155 TRGLLSPDSFIGVAESINLAGELGRWVLRTACAEFSRWRANGVGRNIVLR
TH_0811|M.thermoresistible__bu TRGLLAPDTFIGVAESVNLAGELGRWVMRTACGEFAKWRAEGIGLDAVLR
MLBr_01750|M.leprae_Br4923 TRGLLFPDSFIPVAESINLAGKLGRMVMHSACAEFSRWRSAGVGLDALLR
Mb1389c|M.bovis_AF2122/97 TRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLR
Rv1354c|M.tuberculosis_H37Rv TRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLR
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK VNLFAPSLIDARLPATLRAALERRGLPAELLTVEITEDLVINDLERVTAV
Mvan_4640|M.vanbaalenii_PYR-1 VNLFAPFLRDAQLPSALCQALERRGLPTDLLTVEITEDLVLHDFDVVTGV
MAV_1410|M.avium_104 VNLSTTNLLDIELVGTVERLLANYDLPADALILEITESALVDSVRSRNTV
MSMEG_2196|M.smegmatis_MC2_155 INVSPVQLVTDGFVESVAGIMKEFGLPRGSVCLEITESVVVQDIETTRTT
TH_0811|M.thermoresistible__bu INVSPVQLVTDGFVASVADIIDEFGLDGSSVCLEITESVVVQDIKTTRIT
MLBr_01750|M.leprae_Br4923 INVSPVQLVAEGFVDNVAGTLDEFGLDGSMVCLEITENVVVQNIDATRKT
Mb1389c|M.bovis_AF2122/97 INVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARAT
Rv1354c|M.tuberculosis_H37Rv INVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARAT
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK LGQLRDHGIRVSIDDFGSGYSALSYLRDLLIDEIKLDRSFIAAVTTDPRA
Mvan_4640|M.vanbaalenii_PYR-1 LGQLREQGIRVAIDDFGSGFSALSYLRELRIDEIKLDRHFIATVASDPRA
MAV_1410|M.avium_104 T-ALQRLGIRISIDDYGTGWSSLARLQEVSVDELKLDRIFVARLAHDARS
MSMEG_2196|M.smegmatis_MC2_155 LTGLHNVGVQVAIDDFGTGYSVLSLLKSLPVDTLKIDRSFVAELGSNPGD
TH_0811|M.thermoresistible__bu LEGLNEVGVQVAIDDFGTGYSVLSHLKTLPVDTLKIDKGFVQDLGNSPGD
MLBr_01750|M.leprae_Br4923 LAGLKEVGVHLAIDDFGTGYSVLTHLKSLPVDTIKIDKSFVAELGSNASD
Mb1389c|M.bovis_AF2122/97 LARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSD
Rv1354c|M.tuberculosis_H37Rv LARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSD
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK AVVVRAIIELTHGLGMTVVAEGIEEAATANWLRDSGCDIGQGFYFGKPVD
Mvan_4640|M.vanbaalenii_PYR-1 AAVVRAVIDLTHDLGSVVVAEGVEEPATAAWLRDRGCDMAQGYYFGKPIE
MAV_1410|M.avium_104 VAIVRSTVALADNLGADLVAEGVENEDTLDALRRYGCNITQGFVHTPPLP
MSMEG_2196|M.smegmatis_MC2_155 LPIVRAVIALAGAFGLQLVAEGVETERAALTLLRHGCYRAQGFLLSKPIL
TH_0811|M.thermoresistible__bu LAIVRAIIALAEAFGLQLVAEGVETEAAALTLLRHGCHRAQGFLLSRPIP
MLBr_01750|M.leprae_Br4923 LAIVRAIMALAKEFELEVVAEGVETAVAAQVLLELGCNRAQGFLLSRPVD
Mb1389c|M.bovis_AF2122/97 LVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVP
Rv1354c|M.tuberculosis_H37Rv LVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVP
MAB_1839|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3478|M.gilvum_PYR-GCK PADVPSLGR-LAVGPS-----------------
Mvan_4640|M.vanbaalenii_PYR-1 AADVPGLVR-MAKDPA-----------------
MAV_1410|M.avium_104 PDELRAWIASHAPDPSQSRG-------------
MSMEG_2196|M.smegmatis_MC2_155 GSEMQTLLAKGRVPVHFSAAPRM----------
TH_0811|M.thermoresistible__bu SNEMRELLARGRIPMRFSATP------------
MLBr_01750|M.leprae_Br4923 GAAMESLLAKGVIPMALGTCQSPEPSEHQIHRS
Mb1389c|M.bovis_AF2122/97 GEAMRHMLSARRLPPTCIPATDPALS-------
Rv1354c|M.tuberculosis_H37Rv GEAMRHMLSARRLPPTCIPATDPALS-------
MAB_1839|M.abscessus_ATCC_1997 ---------------------------------