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MAYVRAHDTKQRRNGKVVKTYAVVWREAVRDEFGLPTGATRARRETYPTRDAAEVRRDELNAAKHTHAGT SALAEQRAKGEQPFGFYARAWLDAQAVRVASGKVKQRTVDEYERQLHTYVLGELGSLAVAAVTPAHLERL LTGLVRRQSRQGDRKPITPGTVKHVWDVVRRVLKYAVKHGALDSNPADRVDFSASRATGDHAEFEHHPLT AAQVGALSAAVAGHAREGYEGPELPAYPVYGLLVEFLAYTGLRAAEAAGLEVADLLFSPGPRCSVRVART KDRKNGVWVVGTPKSKRSRRTVPLPPWLAKRMADYLAEVHPRGDEPNAPLWPSRRNGGGHRAVGQRYAVP LDWSQPLALGTFYDTILKPALEAVGLPATRPATKDAPAIRGVRLHDLRHTFAVLQLSAGTHFMQVSKWLG HSTYTLTLDVYGDYIPEEDGGAANNLPEPPAPQRPLEAVDNVVPLRRES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1985 | - | - | 100% (469) | phage integrase family protein |
| M. gilvum PYR-GCK | Mflv_2786 | - | 1e-12 | 29.76% (336) | phage integrase family protein |
| M. gilvum PYR-GCK | Mflv_2927 | - | 4e-09 | 22.67% (375) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2335c | - | 5e-08 | 29.93% (147) | hypothetical protein Mb2335c |
| M. tuberculosis H37Rv | Rv2659c | - | 1e-12 | 25.21% (353) | phiRv2 prophage integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4442 | - | 0.0 | 77.20% (465) | prophage integrase |
| M. avium 104 | MAV_1484 | - | 3e-16 | 23.33% (390) | integrase |
| M. smegmatis MC2 155 | MSMEG_5754 | - | 4e-09 | 23.53% (425) | gp41 protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0529 | - | 1e-15 | 24.93% (345) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_4364 | - | 8e-15 | 27.13% (376) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1985|M.gilvum_PYR-GCK MAYVRAHDTKQRRNGKVVKTYAVVWREAVRDEFGLPTGATRARRETYPTR
MMAR_4442|M.marinum_M MAYVRAHETKQKRNGKALKRYEVVWRESVRDEFGLPTGQTRARQESYPTR
MAV_1484|M.avium_104 ----------------MRQLPSGRWQASYLHNGVV-FKALATFPTKSSAG
Mvan_4364|M.vanbaalenii_PYR-1 ----MAGKKGHRGWGWIRQLPSKRYQASYIGPDLIRHKASTTFGARIDAE
Rv2659c|M.tuberculosis_H37Rv --MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAE
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 ----MAGNTPRGIRKRLNAAGEPRYQVRYLIRDPDAPSGWVETSATFPTL
MSMEG_5754|M.smegmatis_MC2_155 ----MLQRMARIPDYVKVIDLDSGRRYEVRPEVTGADGKRRQKRERFKTL
Mflv_1985|M.gilvum_PYR-GCK DAAEVRRDELNAAKHTH---AGTSALAEQRAKGEQPFGFYARAWLDAQAV
MMAR_4442|M.marinum_M EAAEARRDELNAARHT----TGTSALAEQRKAGELPFGYFARGWLDAQAL
MAV_1484|M.avium_104 HWLQAEEDLIDLDRRRPGEWTPPAERAARRQAEKLTLRTYAKTWLDNKT-
Mvan_4364|M.vanbaalenii_PYR-1 GWLSQERRSIELDT-----WTPPAQRAAEVKAKAVTLGEYSTKWIEDR--
Rv2659c|M.tuberculosis_H37Rv AWLTDRRREIDRQL-----WSPASGQEDRPGAP---FGEYAEGWLKQR--
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 REAKAFKSERDNEAALG-------ARRFDPRLGRTPLSRIWTQFSDSKK-
MSMEG_5754|M.smegmatis_MC2_155 KEAVDHYTAIAGDR----------GRGVHVAPSELTVEDAVDSWLLGQR-
Mflv_1985|M.gilvum_PYR-GCK RVASGKVKQRTVDEYERQLHTYVLGELGSLAVAAVTPAHLERLLTGLVRR
MMAR_4442|M.marinum_M KVAQGKLKQRTVDEYDRLLRTYIFDTLGGTAVAAITPAHCEALLTALVRQ
MAV_1484|M.avium_104 -----KLARRTRDNYQGHLDNHVLPALGDLGLADITPEHVRTWFAGLGNE
Mvan_4364|M.vanbaalenii_PYR-1 -----NVKPRTRSSYRDILRLHIEPRLGSMAMKNLTGEVVRSWYAGLGTD
Rv2659c|M.tuberculosis_H37Rv -----GIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVG
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 ----PAVSPKTWSGYNQHWELRIKPRFGHVPVDEITRADVRAFVDGLTVG
MSMEG_5754|M.smegmatis_MC2_155 ------IRPKTMSAYITSLR-PIVDHLGKRTVQSITKDDLEQVVQALRAG
Mflv_1985|M.gilvum_PYR-GCK QSRQGDRKPITPGTVKHVWDVVRRVLKYAVKHGALDSNPADRVDFSASRA
MMAR_4442|M.marinum_M ASRQGDKKPLTPGTVKHVWDVLRRVLRYALHHGAIVTNPTDRVDFSASRA
MAV_1484|M.avium_104 HETRNA----------QAYAVLNGVFNTAVADDLIDRNPCRIRG----AA
Mvan_4364|M.vanbaalenii_PYR-1 YPRRNS----------HAYGLLHAVCATAVSDGLLQSNPCNIR-----RA
Rv2659c|M.tuberculosis_H37Rv TPTMRA----------HSYSLLRAIMQTALADDLIDSNPCRIS-----GA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 PWAKVS-----------TLRLLRSILDVAHQDGRIHRNPALGVS-----A
MSMEG_5754|M.smegmatis_MC2_155 TSKMGTWN------APTKLTKAAKKVRSPWAASSINPMLARTRSIFEDLV
Mflv_1985|M.gilvum_PYR-GCK TGDHAEFEHHPLTAAQVGALSAAVAGHAREGYEGPELPAYPVYGLLVEFL
MMAR_4442|M.marinum_M TGDHARFEHHPLTSEQVGRLAAAIRGDIAG------LPAYPAYALLVEFM
MAV_1484|M.avium_104 QVKHARRSVVLLDATQLTALAEKM---------------PDDARLGVLLA
Mvan_4364|M.vanbaalenii_PYR-1 MNPPRRRDPVILAVADIAALAEAIQ--------------PRRLRCLVLLA
Rv2659c|M.tuberculosis_H37Rv STARRVHKIRPATLDELETITKAM---------------PDPYQAFVLMA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 GRIPERERHRYLTAQEVRMLATACG----------------DQGDVVTIL
MSMEG_5754|M.smegmatis_MC2_155 NQGVVVRNVAALVKPLATDTEKTMNTLNAEQVTQLLAVTDSHCYGIAWRL
Mflv_1985|M.gilvum_PYR-GCK AYTGLRAAEAAGLEVADLLFSPGPRCSVRVARTKDRKNGVWVVGTPKSKR
MMAR_4442|M.marinum_M AYTGLRAAEVSGLEVGDLVFAPEPRCSVNVRRTKDRKNGAWITGTLKSKK
MAV_1484|M.avium_104 GWCGLRKGEVFALRRGDVAADGS---SVRIERSVTYREGRFEVGPTKTRE
Mvan_4364|M.vanbaalenii_PYR-1 AWCGVRWGEVSELRRKDLSDGCE---VLSVSRAVTRRDGVYRVDTPKSGK
Rv2659c|M.tuberculosis_H37Rv AWLAMRYGELTELRRKDIDLHGE---VARVRRAVVRVGEGFKVTTPKSDA
Mb2335c|M.bovis_AF2122/97 ------------------------------------MTGAGIVETTTN--
MUL_0529|M.ulcerans_Agy99 AYTGLRWSEPVGLRVKDIDLTAR---RLYVRRAAPEVEGHIVIGPPKTRA
MSMEG_5754|M.smegmatis_MC2_155 AVLGLRRGEILALRWDAVDFDAG---TLAISAARLATAGGATTGAPKTKT
. ..
Mflv_1985|M.gilvum_PYR-GCK SRRTVPLPPWLAKRMADYLAEVHPRGDEPNAPLWPSRRNGGGHRAVGQRY
MMAR_4442|M.marinum_M SRRTVPLPPWLAERMADYLATDHPRANEPTAPLWPSRNNGGGHRAKGQRY
MAV_1484|M.avium_104 SRRVVSVPPHVRPAVLEHLQRHVADGDD--ALVFVEPS--TGSFAGE---
Mvan_4364|M.vanbaalenii_PYR-1 GR-AVVIPPHIREDVINHLAENVESGPE--SLLFPAAR--GGHMNDR---
Rv2659c|M.tuberculosis_H37Rv GVRDISIPPHLIPAIEDHLHKHVNPGRE--SLLFPSVNDPNRHLAPS---
Mb2335c|M.bovis_AF2122/97 RVRHVPVPEPVSERLRDELPTEPN------ALVFPSYR--GGHLPIE---
MUL_0529|M.ulcerans_Agy99 GIRTVPLPQVVVDIFKGRITGQAPD--------QPAVTSTNGAMLRSN--
MSMEG_5754|M.smegmatis_MC2_155 SVRTLPMPEDLTAALRRVRKRQKEYRLKLGSKWTDSGYVVVDEFGVAP--
: :* : .
Mflv_1985|M.gilvum_PYR-GCK AVPLDWSQPLALGTFYDTILKPALEAVGLPATRPATKDAPAIRGVRLHDL
MMAR_4442|M.marinum_M AVPLDWSQPLAMGTFYDTIVKPALEAVALPASRPATKDAPATRGVRLHDL
MAV_1484|M.avium_104 -------------KRFRTAWESARAAIGQPD-------------MHFHDL
Mvan_4364|M.vanbaalenii_PYR-1 -------------VFSREYFSDALKAIGRQG-------------VRVHDL
Rv2659c|M.tuberculosis_H37Rv -------------ALYRMFYK-ARKAAGRPD-------------LRVHDL
Mb2335c|M.bovis_AF2122/97 --------------EYRRAFDKGCKAVGIAD-------------LVPHGL
MUL_0529|M.ulcerans_Agy99 ------------NWRRHTHWNKALKSTDLAP-------------LTIHDL
MSMEG_5754|M.smegmatis_MC2_155 -----------YPDTLTAAWRKTLANAGLPH-------------VRLHDA
: *.
Mflv_1985|M.gilvum_PYR-GCK RHTFAVLQLSAGTHFMQVSKWLGHSTYTLTLDVYGDYIPEEDGGAANNLP
MMAR_4442|M.marinum_M RHTFAVLQLSAGTHFMQVSKWLGHSTFTLTLDTYGDYIPEQDGGALNTLP
MAV_1484|M.avium_104 RHAAGVMAAQTGATVRELMDRLGHTSPNMSMR-YQHTAEGRAAALADKLS
Mvan_4364|M.vanbaalenii_PYR-1 RHFAGTQTAQV-ANLAESMARLGHSTVKASLI-YQGLVTGRDAAIADALS
Rv2659c|M.tuberculosis_H37Rv RHSGAVLAASTGATLAELMQRLGHSTAGAALR-YQHAAKGRDREIAALLS
Mb2335c|M.bovis_AF2122/97 RHTTASLAISAGANVKVVQRLLGHATAAMTLDRHGHLLSDDLAGVAGLLV
MUL_0529|M.ulcerans_Agy99 RHTYASLARKSGADLRYVQKTMGHSTPTVTANIYSDLYADELDQVATNLD
MSMEG_5754|M.smegmatis_MC2_155 RHSCATLMHLSGVPTVVIAAWLGHQDPGFTLRTYAHSNHDALADAAAMLG
** . . :** : : *
Mflv_1985|M.gilvum_PYR-GCK EPPAPQRPLEAVDNVVPLR-RES----
MMAR_4442|M.marinum_M EPPAPVRPTETVNNVVNLFGRQSS---
MAV_1484|M.avium_104 ALASTNP--------------------
Mvan_4364|M.vanbaalenii_PYR-1 QLAVGES--------------------
Rv2659c|M.tuberculosis_H37Rv KLAENQEM-------------------
Mb2335c|M.bovis_AF2122/97 QAIKSAAASLRYSDPDSVAVENISAAS
MUL_0529|M.ulcerans_Agy99 QLHATEIQTPTTGQEPDEPNQPSSA--
MSMEG_5754|M.smegmatis_MC2_155 SITTGKKKEAK----------------