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AYVRAHETKQKRNGKALKRYEVVWRESVRDEFGLPTGQTRARQESYPTREAAEARRDELNAARHTTGTSA LAEQRKAGELPFGYFARGWLDAQALKVAQGKLKQRTVDEYDRLLRTYIFDTLGGTAVAAITPAHCEALLT ALVRQASRQGDKKPLTPGTVKHVWDVLRRVLRYALHHGAIVTNPTDRVDFSASRATGDHARFEHHPLTSE QVGRLAAAIRGDIAGLPAYPAYALLVEFMAYTGLRAAEVSGLEVGDLVFAPEPRCSVNVRRTKDRKNGAW ITGTLKSKKSRRTVPLPPWLAERMADYLATDHPRANEPTAPLWPSRNNGGGHRAKGQRYAVPLDWSQPLA MGTFYDTIVKPALEAVALPASRPATKDAPATRGVRLHDLRHTFAVLQLSAGTHFMQVSKWLGHSTFTLTL DTYGDYIPEQDGGALNTLPEPPAPVRPTETVNNVVNLFGRQSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4442 | - | - | 100% (464) | prophage integrase |
| M. marinum M | MMAR_4848 | - | 3e-15 | 26.45% (431) | prophage integrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2335c | - | 2e-06 | 29.19% (161) | hypothetical protein Mb2335c |
| M. gilvum PYR-GCK | Mflv_1985 | - | 0.0 | 77.20% (465) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2659c | - | 8e-14 | 25.91% (386) | phiRv2 prophage integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_2217 | - | 3e-17 | 24.76% (420) | traSA:integrase fusion protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0529 | - | 3e-15 | 25.75% (431) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_2508 | - | 6e-12 | 24.37% (398) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4442|M.marinum_M MAYVRAHETKQKRNGKALKRYEVVWRESVRDEFGLPTGQTRARQESYPTR
Mflv_1985|M.gilvum_PYR-GCK MAYVRAHDTKQRRNGKVVKTYAVVWREAVRDEFGLPTGATRARRETYPTR
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MAV_2217|M.avium_104 --MDLWTKTVRDPDDTIRTVPSARHGRGMRWRATYVDDQSREHSRSFGRK
Rv2659c|M.tuberculosis_H37Rv ----MTQTGKRQRRK--FGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAK
Mvan_2508|M.vanbaalenii_PYR-1 ---MARGEGRKTRQAGTFGTVQQLPSGRYRAMYYGPDRRRYKAPTTFRAK
MUL_0529|M.ulcerans_Agy99 ----MAGNTPRGIRKRLNAAGEPRYQVRYLIRDPDAPSGWVETSATFPTL
MMAR_4442|M.marinum_M EAAEARRDELNAARHT-TGTSALAEQRKAGELPFGYFARGWLDAQALKVA
Mflv_1985|M.gilvum_PYR-GCK DAAEVRRDELNAAKHTHAGTSALAEQRAKGEQPFGFYARAWLDAQAVRVA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MAV_2217|M.avium_104 VDAQRWLDEVTAAVVT-----GQYVDPKAGQITFRDYAERWRKMQVQRPS
Rv2659c|M.tuberculosis_H37Rv IDAEAWLTDRRREIDRQLWSPASGQEDRPG-APFGEYAEGWLKQRGIKDR
Mvan_2508|M.vanbaalenii_PYR-1 ADARGWLALRQAEIISKAWTPPEAAPKITR-TTFADYARNWIKQRDLKQH
MUL_0529|M.ulcerans_Agy99 REAKAFKSERDNEAALGARRFDPRLGRTPLSRIWTQFSDSKKPAVSPKTW
MMAR_4442|M.marinum_M QGKLKQRTVDEYDRLLRTYIFDTLGGTAVAAITPAHCEALLTALVRQASR
Mflv_1985|M.gilvum_PYR-GCK SGKVKQRTVDEYERQLHTYVLGELGSLAVAAVTPAHLERLLTGLVRRQSR
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MAV_2217|M.avium_104 S-------RAHIETMLRRHAYPTLGDRQLTSILPSDVQAWVKGLQ-----
Rv2659c|M.tuberculosis_H37Rv T-------RAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVG---
Mvan_2508|M.vanbaalenii_PYR-1 T-------REHYEVLLERHLISPFGSLPLSSITVDDVRGWYATFATE---
MUL_0529|M.ulcerans_Agy99 SG---------YNQHWELRIKPRFGHVPVDEITRADVRAFVDGLTVG---
MMAR_4442|M.marinum_M QGDKKPLTPGTVKHVWDVLRRVLRYALHHGAIVTNPTDRVDFSASRATGD
Mflv_1985|M.gilvum_PYR-GCK QGDRKPITPGTVKHVWDVVRRVLKYAVKHGALDSNPADRVDFSASRATGD
Mb2335c|M.bovis_AF2122/97 ----------------------------------MTGAGIVETTTNRV--
MAV_2217|M.avium_104 ------LAPATVGVVHGLVSTVMKSAIRDRRLAANPCDGTKLPKVQRP--
Rv2659c|M.tuberculosis_H37Rv -------TPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVH-
Mvan_2508|M.vanbaalenii_PYR-1 -------TPTLRSHTYGLLRTILGTAASDGKISSNPCLIRGAGTTKRVK-
MUL_0529|M.ulcerans_Agy99 --------PWAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGRIPERE-
.
MMAR_4442|M.marinum_M HARFEHHPLTSEQVGRLAAAIRGDIAG------LPAYPAYALLVEFMAYT
Mflv_1985|M.gilvum_PYR-GCK HAEFEHHPLTAAQVGALSAAVAGHAREGYEGPELPAYPVYGLLVEFLAYT
Mb2335c|M.bovis_AF2122/97 ----RHVPVPEPVSERLRDELP---------------TEPNALVFPSYRG
MAV_2217|M.avium_104 ----QIVPLTTEQVEAVRAELP---------------AELQALVTLAAGT
Rv2659c|M.tuberculosis_H37Rv ----KIRPATLDELETITKAMP---------------DPYQAFVLMAAWL
Mvan_2508|M.vanbaalenii_PYR-1 ----KIRPATLPEIEKITTEMP---------------EQYQAMILLAAWC
MUL_0529|M.ulcerans_Agy99 ----RHRYLTAQEVRMLATACG----------------DQGDVVTILAYT
. . : .:
MMAR_4442|M.marinum_M GLRAAEVSGLEVGD--------LVFAPEPRCSVNVRRTKDRKNGAWITGT
Mflv_1985|M.gilvum_PYR-GCK GLRAAEAAGLEVAD--------LLFSPGPRCSVRVARTKDRKNGVWVVGT
Mb2335c|M.bovis_AF2122/97 GHLPIEEY------------------------------------------
MAV_2217|M.avium_104 GLRQGECFGLTVDR--------VRFL--ERVLTVDRQLVTVAGQAPTFGP
Rv2659c|M.tuberculosis_H37Rv AMRYGELTELRRKD------IDLHGE-----VARVRRAVVRVGEGFKVTT
Mvan_2508|M.vanbaalenii_PYR-1 ALRFGELTELRRKDIVLTTTVDLEGETVHMGVIRVERAVVRVDDGYLVTT
MUL_0529|M.ulcerans_Agy99 GLRWSEPVGLRVKD-----------IDLTARRLYVRRAAPEVEGHIVIGP
. *
MMAR_4442|M.marinum_M LKSKKSRRTVPLPPWLAERMADYLATDHPRANEPTAPLWPSRNNGGGHRA
Mflv_1985|M.gilvum_PYR-GCK PKSKRSRRTVPLPPWLAKRMADYLAEVHPRGDEPNAPLWPSRRNGGGHRA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
MAV_2217|M.avium_104 PKTRASNRAIPLPKVVADALAAHLAAFPAEPD------------------
Rv2659c|M.tuberculosis_H37Rv PKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRE-----------------
Mvan_2508|M.vanbaalenii_PYR-1 PKSDAGTRDVAIPPHLVPVIHDHLAVHVDGGPD-----------------
MUL_0529|M.ulcerans_Agy99 PKTRAGIRTVPLPQVVVDIFKGRITGQAPDQP------------------
MMAR_4442|M.marinum_M KGQRYAVPLDWSQPLAMGTFYDTIVKPALEAVALPASRPATKDAPATRGV
Mflv_1985|M.gilvum_PYR-GCK VGQRYAVPLDWSQPLALGTFYDTILKPALEAVGLPATRPATKDAPAIRGV
Mb2335c|M.bovis_AF2122/97 -----------------------------RRAFDKGCKAVGIADLVPHG-
MAV_2217|M.avium_104 -----------------GLVFTQQGKPITRSTFGYRWRAAVKEAKLPHGT
Rv2659c|M.tuberculosis_H37Rv ---------------SLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDL
Mvan_2508|M.vanbaalenii_PYR-1 ---------------ALLFPAAHG--RHLAPATLYRQFYKARVAADRPDL
MUL_0529|M.ulcerans_Agy99 -----------------AVTSTNGAMLRSNNWRRHTHWNKALKSTDLAPL
MMAR_4442|M.marinum_M RLHDLRHTFAVLQLSAGTHFMQVSKWLGHSTFTLTLDTYGDYIPEQDGGA
Mflv_1985|M.gilvum_PYR-GCK RLHDLRHTFAVLQLSAGTHFMQVSKWLGHSTYTLTLDVYGDYIPEEDGGA
Mb2335c|M.bovis_AF2122/97 ----LRHTTASLAISAGANVKVVQRLLGHATAAMTLDRHGHLLSDDLAGV
MAV_2217|M.avium_104 GFHALRHYYASLLIRHGESVKTVQARLGHASAVETLDTYSHLWPDSDDRT
Rv2659c|M.tuberculosis_H37Rv RVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALR-YQHAAKGRDREI
Mvan_2508|M.vanbaalenii_PYR-1 RFHDLRHSGAVLAAATGATLAELMARLGHSTPQAAMR-YQHAAQGRDQAI
MUL_0529|M.ulcerans_Agy99 TIHDLRHTYASLARKSGADLRYVQKTMGHSTPTVTANIYSDLYADELDQV
*** * * * . : :**:: : : .
MMAR_4442|M.marinum_M LNTLPEPPAPVRPTETVNNVVNLFGRQSS---
Mflv_1985|M.gilvum_PYR-GCK ANNLPEPPAPQRPLEAVDNVVPLR-RES----
Mb2335c|M.bovis_AF2122/97 AGLLVQAIKSAAASLRYSDPDSVAVENISAAS
MAV_2217|M.avium_104 RDAIDSVLGSTAYRLRTGQPATS---------
Rv2659c|M.tuberculosis_H37Rv AALLSKLAENQEM-------------------
Mvan_2508|M.vanbaalenii_PYR-1 AAALSKIALGQ---------------------
MUL_0529|M.ulcerans_Agy99 ATNLDQLHATEIQTPTTGQEPDEPNQPSSA--
: .