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MQRRNRRSGVEDRWRKTVTRPDGTTERVPSARDGKGLRWLARYVDERGREHSKSFARKPDAQQWLDGQTA AVVTGSHVAPRTAQMTVEQWCDTWIGGYAVNRESTVRQARTHIKHIVAEFGDQPLSALRPSQVKAWVAGL KKADVAPSYVYALHSRLSQICGDAVHDGVLARNPCSRRTAPPMGTQKPYVATTEQVWALHDAMPDHLRVA VLLGAFVGLRVAEVAALRVSDVDFIRGVVHPVQQWPDKPLKTDGSAQPVPIPNDLALLLSASVKRYPSPM MVTRGVAGETAPPWVIEREVRAARSSIDGLPEEFSFHDLRHYLASLLIASGADIKTVQARMRHGSARTTL DTYGHLWPDADESTRTAIASVIAERMDSNGAADQLRTSGTD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2927 | - | - | 100% (391) | phage integrase family protein |
| M. gilvum PYR-GCK | Mflv_3899 | - | 2e-25 | 26.99% (389) | phage integrase family protein |
| M. gilvum PYR-GCK | Mflv_1985 | - | 4e-09 | 22.67% (375) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2918c | xerC | 1e-08 | 25.50% (251) | site-specific tyrosine recombinase XerC |
| M. tuberculosis H37Rv | Rv2659c | - | 7e-18 | 25.00% (364) | phiRv2 prophage integrase |
| M. leprae Br4923 | MLBr_01365 | xerD | 3e-06 | 28.74% (261) | site-specific tyrosine recombinase XerD |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 4e-10 | 25.67% (261) | site-specific tyrosine recombinase XerC |
| M. marinum M | MMAR_4848 | - | 5e-13 | 26.40% (356) | prophage integrase |
| M. avium 104 | MAV_2266 | - | 1e-165 | 72.09% (387) | phage-related integrase |
| M. smegmatis MC2 155 | MSMEG_5754 | - | 2e-11 | 26.47% (340) | gp41 protein |
| M. thermoresistible (build 8) | TH_0846 | xerC | 1e-07 | 24.80% (254) | PROBABLE INTEGRASE/RECOMBINASE XERC |
| M. ulcerans Agy99 | MUL_0529 | - | 4e-14 | 26.74% (273) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_2508 | - | 2e-21 | 25.07% (379) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2927|M.gilvum_PYR-GCK -MQRRNRRSGVEDRWRKTVTRPDGTTERVPSARDGKGLRWLARYVDERGR
MAV_2266|M.avium_104 MTQKRNLRAGVEDRWNKTVRDEHGNPQTVPSATYGKGKRWRARYVDEQGR
Rv2659c|M.tuberculosis_H37Rv --MTQTGKRQRRK--FGRIRQFNSG--RWQASYTGPDGRVYIAPKTFNAK
Mvan_2508|M.vanbaalenii_PYR-1 -MARGEGRKTRQAGTFGTVQQLPSG--RYRAMYYGPDRRRYKAPTTFRAK
MMAR_4848|M.marinum_M --MAGSVPRGIRKRTNSAGQARYQV--RYLVRDPNSPSGWVETSSTFATM
MUL_0529|M.ulcerans_Agy99 --MAGNTPRGIRKRLNAAGEPRYQV--RYLIRDPDAPSGWVETSATFPTL
Mb2918c|M.bovis_AF2122/97 ------------------------------------------------MQ
TH_0846|M.thermoresistible__bu ----------------------------------------------MSVD
MAB_3204c|M.abscessus_ATCC_199 --------------------------------------------MTPQLA
MLBr_01365|M.leprae_Br4923 -------------------------------------------MTTAALQ
MSMEG_5754|M.smegmatis_MC2_155 ----MLQRMARIPDYVKVIDLDSGRRYEVRPEVTGADGKRRQKRERFKTL
Mflv_2927|M.gilvum_PYR-GCK EHSKSFARKPDAQQWLDGQTAAVVTGSH--------VAPRTAQMTVEQWC
MAV_2266|M.avium_104 EHVQSFTRKVDAQQWLTNQTATIVAGTH--------VAPRDAKLTVQQWC
Rv2659c|M.tuberculosis_H37Rv IDAEAWLTDR--RREIDRQLWSPASG-----------QEDRPGAPFGEYA
Mvan_2508|M.vanbaalenii_PYR-1 ADARGWLALR--QAEIISKAWTPPEA-----------APKITRTTFADYA
MMAR_4848|M.marinum_M REARAFKADRDGEAAIGARRFDPRLG-----------RASLS-AIWTQYS
MUL_0529|M.ulcerans_Agy99 REAKAFKSERDNEAALGARRFDPRLG-----------RTPLS-RIWTQFS
Mb2918c|M.bovis_AF2122/97 AILDEFDEYLALQCGRSVHTRRAYLG------------------------
TH_0846|M.thermoresistible__bu TVLDEFADYLALQRGRSPHTCRAYLG------------------------
MAB_3204c|M.abscessus_ATCC_199 AILDEFAEHLALERGRSVHTQRAYRG------------------------
MLBr_01365|M.leprae_Br4923 TQLQGYLDYLIIERSIAANTLSSYRR------------------------
MSMEG_5754|M.smegmatis_MC2_155 KEAVDHYTAIAGDRGRGVHVAPSELTVEDAVDSWLLGQRIRPKTMSAYIT
.
Mflv_2927|M.gilvum_PYR-GCK DTWIGGYAVNRESTVRQARTHIKHIVAEFGD--QPLSALRPSQVKAWVAG
MAV_2266|M.avium_104 DTWIEGYKVHREGTVREARTHIRQIVTEFGD--TPLTQVRPSQVKAWTAR
Rv2659c|M.tuberculosis_H37Rv EGWLKQRGIKDRTRAHYRKLLDNHILATFAD--TDLRDITPAAVRRWYAT
Mvan_2508|M.vanbaalenii_PYR-1 RNWIKQRDLKQHTREHYEVLLERHLISPFGS--LPLSSITVDDVRGWYAT
MMAR_4848|M.marinum_M A--SKQPAVSPKTWSGYAQHWELRISPRFGH--VPVDEISRKDVQQFIGG
MUL_0529|M.ulcerans_Agy99 D--SKKPAVSPKTWSGYNQHWELRIKPRFGH--VPVDEITRADVRAFVDG
Mb2918c|M.bovis_AF2122/97 DLRSLFAFLADR--GSSLDALTLSVLRSWLA--ATAG-------AGAART
TH_0846|M.thermoresistible__bu DLRSLFDFVEQRSPGSGLGGLSLPVLRAWLA--AQAA-------DGSART
MAB_3204c|M.abscessus_ATCC_199 DLTLLFDHLSASNPEATLADLSLPVLRSWLG--AQAR-------QGAARS
MLBr_01365|M.leprae_Br4923 DLIRYSKHLSDRG-IEDLAKVGEHDVSEFLV--ALRRGDPDSGVAALSAV
MSMEG_5754|M.smegmatis_MC2_155 SLRPIVDHLGKRTVQSITKDDLEQVVQALRAGTSKMGTWNAPTKLTKAAK
:
Mflv_2927|M.gilvum_PYR-GCK LKKADVAPSYVYALHSRLSQICGDAVHDGVLARNPCSRRTAPPMG-TQKP
MAV_2266|M.avium_104 LRADGMKASYIYALHSRLSQIMADAVHDGVLGRNPCSRRTAPPMG-KAKV
Rv2659c|M.tuberculosis_H37Rv TAVGT--PTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKI
Mvan_2508|M.vanbaalenii_PYR-1 FATET--PTLRSHTYGLLRTILGTAASDGKISSNPCLIRGAGTTKRVKKI
MMAR_4848|M.marinum_M LTVG---PWAKLATLRLLRSILDMAREDGRIHINPAQGVSSGRIPARERH
MUL_0529|M.ulcerans_Agy99 LTVG---PWAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGRIPERERH
Mb2918c|M.bovis_AF2122/97 TLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALR
TH_0846|M.thermoresistible__bu TLARRTSAVKTFTAWAVRQGLLSTDPALRLQVPKARRTLPAVLRRDQALA
MAB_3204c|M.abscessus_ATCC_199 TVARRTSAVKIFTAWATRRGLLPTDPAIRLQQPKSRRTLPAVLRQDQAAA
MLBr_01365|M.leprae_Br4923 SAARALIAVRGLHRFAVAEGLVDLDVARAVRPPTPGRRLPKSLTVDEVLA
MSMEG_5754|M.smegmatis_MC2_155 KVRSPWAASSINPMLARTRSIFEDLVNQGVVVRNVAALVKPLATDTEKTM
. : .
Mflv_2927|M.gilvum_PYR-GCK YVATTEQVWALHDAMPDHLRVAVLLGAFVGLRVAEVAALRVSD-------
MAV_2266|M.avium_104 YVATTEQVWALHDAVPDHLKVAVLLGAFAGLRVAEVSGLRVSD-------
Rv2659c|M.tuberculosis_H37Rv RPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKD------I
Mvan_2508|M.vanbaalenii_PYR-1 RPATLPEIEKITTEMPEQYQAMILLAAWCALRFGELTELRRKDIVLTTTV
MMAR_4848|M.marinum_M RYLSATEVAALAHACGDQ-GDIVTILAFTGLRWSELVGLRVGD------I
MUL_0529|M.ulcerans_Agy99 RYLTAQEVRMLATACGDQ-GDVVTILAYTGLRWSEPVGLRVKD------I
Mb2918c|M.bovis_AF2122/97 AMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDD-------
TH_0846|M.thermoresistible__bu AMAAADSGAQQKDPIALRDRLIVEMLYATGIRVSELCGLDIDD-------
MAB_3204c|M.abscessus_ATCC_199 AMEAAHSGAEQDDPMALRDRLIVEMLYATGIRVSELCGLDIDD-------
MLBr_01365|M.leprae_Br4923 LLESVGGESRADGPLVLRNRALLELLYSTGSRISEAVGLDVDD-------
MSMEG_5754|M.smegmatis_MC2_155 NTLNAEQVTQLLAVTDSHCYGIAWRLAVLGLRRGEILALRWDAVDFDAG-
. * .* *
Mflv_2927|M.gilvum_PYR-GCK -----------VDFIRGVVHPVQQWPDKPLKTDGSAQPVPIPNDLALLLS
MAV_2266|M.avium_104 -----------VDFIRGVVHPKQQWSDKPLKTEGSSAPIPIPQDLALLLS
Rv2659c|M.tuberculosis_H37Rv DLHGE-----VARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIE
Mvan_2508|M.vanbaalenii_PYR-1 DLEGETVHMGVIRVERAVVRVDDGYLVTTPKSDAGTRDVAIPPHLVPVIH
MMAR_4848|M.marinum_M DLKAR-----RLYVRQAAPDVEGRIIVGPPKTRAAVRTVPLPRIVIDALK
MUL_0529|M.ulcerans_Agy99 DLTAR-----RLYVRRAAPEVEGHIVIGPPKTRAGIRTVPLPQVVVDIFK
Mb2918c|M.bovis_AF2122/97 -----------IDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRR
TH_0846|M.thermoresistible__bu -----------VDTDRHLARVLGKGGRQRTVPFGEPARGALTDWLTDGRP
MAB_3204c|M.abscessus_ATCC_199 -----------IDRPRKVLRVLGKGDKERTVPFGDPAADALSAWLDRGRP
MLBr_01365|M.leprae_Br4923 -----------VDTQARTVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRS
MSMEG_5754|M.smegmatis_MC2_155 ----------TLAISAARLATAGGATTGAPKTKTSVRTLPMPEDLTAALR
. .: :
Mflv_2927|M.gilvum_PYR-GCK ASVKRYP-----------SPMMVTRGVAGETAPPWVIEREVRAARSSIDG
MAV_2266|M.avium_104 ASVQKYP-----------AEMMVTNGLGTDRCGPWIIERAIRDVRRGIDG
Rv2659c|M.tuberculosis_H37Rv DHLHKHVNP------GRESLLFPSVNDPNRHLAPSALYRMFYKARKAAG-
Mvan_2508|M.vanbaalenii_PYR-1 DHLAVHVDG------GPDALLFPAAHG--RHLAPATLYRQFYKARVAAD-
MMAR_4848|M.marinum_M PRIENRS---------TKEQAITSPNGGFLRSNNWRRHTHWNKALKKTG-
MUL_0529|M.ulcerans_Agy99 GRITGQA---------PDQPAVTSTNGAMLRSNNWRRHTHWNKALKSTD-
Mb2918c|M.bovis_AF2122/97 ALVTAESG----------HALLLGARG--RRLDVRQARTAVHQTVAAVDG
TH_0846|M.thermoresistible__bu ALATAESG----------PALLLGVRG--RRLDPRQARTVVHQTVAAVAG
MAB_3204c|M.abscessus_ATCC_199 HLAVPASG----------AALLLGARG--RRVDPRQVRTVVHQTMSAVPG
MLBr_01365|M.leprae_Br4923 DLARRGPGM------LATPAIFLNARG--GRLSRQSAWQVLQDAAEHAGI
MSMEG_5754|M.smegmatis_MC2_155 RVRKRQKEYRLKLGSKWTDSGYVVVDEFGVAPYPDTLTAAWRKTLANAG-
.
Mflv_2927|M.gilvum_PYR-GCK LPEEFSFHDLRHYLASLLIASGADIKTVQARMRHGSARTTLDTYGHLWPD
MAV_2266|M.avium_104 LPEGFSFHDLRHYLASLLIARGCDVKTVQARLRHSSAKTTLDTYSHLWPD
Rv2659c|M.tuberculosis_H37Rv -RPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAAL---------
Mvan_2508|M.vanbaalenii_PYR-1 -RPDLRFHDLRHSGAVLAAATGATLAELMARLGHSTPQAAM---------
MMAR_4848|M.marinum_M -LAPLTIHDLRHTYASLARKSGADLRYVQKTMGHSTPTVTANIYSDLYSD
MUL_0529|M.ulcerans_Agy99 -LAPLTIHDLRHTYASLARKSGADLRYVQKTMGHSTPTVTANIYSDLYAD
Mb2918c|M.bovis_AF2122/97 -APDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQ---------
TH_0846|M.thermoresistible__bu -APDIGPHGLRHSAATHLLEGGADLRIVQELLGHTSLATTQ---------
MAB_3204c|M.abscessus_ATCC_199 -APDIGPHGLRHSAATHLLEGGADLRVVQELLGHSTLATTQ---------
MLBr_01365|M.leprae_Br4923 -TSGVSPHMLRHSFATHLLEGGADIRVVQELMGHASVTTTQ---------
MSMEG_5754|M.smegmatis_MC2_155 -LPHVRLHDARHSCATLMHLSGVPTVVIAAWLGHQDPGFTLR--------
. * ** * * : : * :
Mflv_2927|M.gilvum_PYR-GCK ADESTRTAIASVIAERMDS-NGAADQLRTSGTD---------
MAV_2266|M.avium_104 ADESTRSAIGAVLAERVDSGETTADELRTMRPGRGRRRRSGV
Rv2659c|M.tuberculosis_H37Rv RYQHAAKGRDREIAALLSKLAENQEM----------------
Mvan_2508|M.vanbaalenii_PYR-1 RYQHAAQGRDQAIAAALSKIALGQ------------------
MMAR_4848|M.marinum_M ELDHVATNLDRLNDVAKDQAN-GQEPDTPKHP----------
MUL_0529|M.ulcerans_Agy99 ELDQVATNLDQLHATEIQTPTTGQEPDEPNQPSSA-------
Mb2918c|M.bovis_AF2122/97 LYTHVAVARLRAVHERAHPRA---------------------
TH_0846|M.thermoresistible__bu LYTHVTVERLRAVHDQAHPRA---------------------
MAB_3204c|M.abscessus_ATCC_199 LYTHVTVARLRAVHDQAHPRA---------------------
MLBr_01365|M.leprae_Br4923 IYTLVTVQALREVWAGAHPRAK--------------------
MSMEG_5754|M.smegmatis_MC2_155 TYAHSNHDALADAAAMLGSITTGKKKEAK-------------