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MLQRMARIPDYVKVIDLDSGRRYEVRPEVTGADGKRRQKRERFKTLKEAVDHYTAIAGDRGRGVHVAPSE LTVEDAVDSWLLGQRIRPKTMSAYITSLRPIVDHLGKRTVQSITKDDLEQVVQALRAGTSKMGTWNAPTK LTKAAKKVRSPWAASSINPMLARTRSIFEDLVNQGVVVRNVAALVKPLATDTEKTMNTLNAEQVTQLLAV TDSHCYGIAWRLAVLGLRRGEILALRWDAVDFDAGTLAISAARLATAGGATTGAPKTKTSVRTLPMPEDL TAALRRVRKRQKEYRLKLGSKWTDSGYVVVDEFGVAPYPDTLTAAWRKTLANAGLPHVRLHDARHSCATL MHLSGVPTVVIAAWLGHQDPGFTLRTYAHSNHDALADAAAMLGSITTGKKKEAK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5754 | - | - | 100% (404) | gp41 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2786 | - | 5e-49 | 31.98% (419) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2659c | - | 4e-08 | 26.26% (179) | phiRv2 prophage integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1723 | - | 1e-15 | 23.33% (390) | putative phage integrase |
| M. marinum M | MMAR_4848 | - | 3e-15 | 25.85% (325) | prophage integrase |
| M. avium 104 | MAV_0253 | - | 1e-139 | 60.50% (400) | site-specific recombinase, phage integrase family protein |
| M. thermoresistible (build 8) | TH_3114 | - | 5e-06 | 28.42% (190) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | MUL_0529 | - | 2e-13 | 25.60% (332) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_3747 | - | 7e-49 | 31.98% (419) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5754|M.smegmatis_MC2_155 -----------------------------MLQRMARIPDYVKVIDLDSGR
MAV_0253|M.avium_104 ---------------------------------MAKIPDYVKALDLDSGR
Mflv_2786|M.gilvum_PYR-GCK ---------MQATTVQTPAGAWMTTTDKPPPKRTRRTEPITRRNAKNGAV
Mvan_3747|M.vanbaalenii_PYR-1 ---------MQATTVQTPAGAWMTTTDKPPPKRTRRTEPIMRRNAKNGAV
MMAR_4848|M.marinum_M -------------------------------MAGSVPRGIRKRTNSAGQA
MUL_0529|M.ulcerans_Agy99 -------------------------------MAGNTPRGIRKRLNAAGEP
Rv2659c|M.tuberculosis_H37Rv ---------------------------------MTQTGKRQRRKFGRIRQ
MAB_1723|M.abscessus_ATCC_1997 MEQTERVKKRPACKCKHVYFAHPNEGPCNQCGDCPKYRERERRERGEGGL
TH_3114|M.thermoresistible__bu ----------------------------MARTQRIALTDRPDTYTVLGAD
MSMEG_5754|M.smegmatis_MC2_155 RYEVR----PEV--TGADGKRRQKRERFKTLKEAVDHYTAIAGDRG----
MAV_0253|M.avium_104 RYEVR----PEV--TGPDGKRKQQRKRFKTLKEATDFYTRIAGDRS----
Mflv_2786|M.gilvum_PYR-GCK SYTFQ----VDVG-THADGTRDRQRFTFSTFAEARREYRKISTEVA----
Mvan_3747|M.vanbaalenii_PYR-1 SYTFQ----VDVG-THADGTRDRQRFTFSTFAEARREYRKISTEVA----
MMAR_4848|M.marinum_M RYQVR----YLVRDPNSPSGWVETSSTFATMREARAFKADRDGEAA----
MUL_0529|M.ulcerans_Agy99 RYQVR----YLIRDPDAPSGWVETSATFPTLREAKAFKSERDNEAA----
Rv2659c|M.tuberculosis_H37Rv FNSGR----WQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLW
MAB_1723|M.abscessus_ATCC_1997 FQRADGMWVGSVEVPSEDGLRRRQTVSAKDKGVALDKLRDLRSAIR----
TH_3114|M.thermoresistible__bu HLPVD----PAEEYLQFLRDDAASPNTVKAYAAGLAAWWTLLEYTG----
.
MSMEG_5754|M.smegmatis_MC2_155 --RGVHVAPSELTVEDAVDSWLL----GQR-IRPKTMSAYITSLRP-IVD
MAV_0253|M.avium_104 --RGVHVAPSELTVEAAVDAWLA----AQR-VRTKAMTGYVTALRP-LVD
Mflv_2786|M.gilvum_PYR-GCK --AGTFVKRDLTTVAEYLARWLD----GRRDVRVNTLAGYRHSLKP-VID
Mvan_3747|M.vanbaalenii_PYR-1 --AGTFVKRDLTTVAEYLGRWLD----GRRDVRVNTLAGYRHSLKP-VID
MMAR_4848|M.marinum_M --IGARRFDPRLGRASLSAIWTQYSASKQPAVSPKTWSGYAQHWELRISP
MUL_0529|M.ulcerans_Agy99 --LGARRFDPRLGRTPLSRIWTQFSDSKKPAVSPKTWSGYNQHWELRIKP
Rv2659c|M.tuberculosis_H37Rv SPASGQEDRPGAPFGEYAEGWLK-----QRGIKDRTRAHYRKLLDNHILA
MAB_1723|M.abscessus_ATCC_1997 --SGKSPTSSKVHLEQWLNHWLET--IQKPRVRPTTYKYYETTVRLYILP
TH_3114|M.thermoresistible__bu ---TDWREVSTAMFGQFLAYLRSGDLPGTARIGAPPTWLGPASTQLRAAA
: .
MSMEG_5754|M.smegmatis_MC2_155 HLG-KRTVQSITKDDLEQVVQALRAGT-----------------------
MAV_0253|M.avium_104 HLG-GKAVQAVTKADIEKVVAALRGGT-----------------------
Mflv_2786|M.gilvum_PYR-GCK NLG-GLGLQQLRTSDIDALVTLRLNGTPISQRERRGRRAAEVLAYLRSRS
Mvan_3747|M.vanbaalenii_PYR-1 NLG-GLGLQQLRTSDIDALVTLRLNGTPISQRERRGRRAAEVLAYLRSRS
MMAR_4848|M.marinum_M RFG-HVPVDEISRKDVQQFIGGLTVGP-----------------------
MUL_0529|M.ulcerans_Agy99 RFG-HVPVDEITRADVRAFVDGLTVGP-----------------------
Rv2659c|M.tuberculosis_H37Rv TFA-DTDLRDITPAAVRRWYATTAVGT-----------------------
MAB_1723|M.abscessus_ATCC_1997 FIDGRTQLGKLTPAQVRKMIAKNGTRN-----------------------
TH_3114|M.thermoresistible__bu VLACYRYHADAHGLPVPYRRLFTSRGK-----------------------
: :
MSMEG_5754|M.smegmatis_MC2_155 -------------------------------SKMGTWNAPTKLTKAAKKV
MAV_0253|M.avium_104 -------------------------------SKMGTWNAPEKIK--GKQV
Mflv_2786|M.gilvum_PYR-GCK GGAQYADVRDELGNPGVKALDRLVASGEVIRPSRGRYVAVRDSDPVQSKI
Mvan_3747|M.vanbaalenii_PYR-1 GGAQYADVRDELGNPGVKALDRLVASGEVIRPSRGRYVAVRDSDPVQSKI
MMAR_4848|M.marinum_M --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 --------------------------------------------------
Rv2659c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1723|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3114|M.thermoresistible__bu --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 RSPWAASSINPMLARTRSIFEDLVNQGVVVRNVAALVKPLATDTEKTMNT
MAV_0253|M.avium_104 RAKWGPSGTNHFIRRSRAVFEDLVQQGVLGRNPAALVQPVP-MARAELNT
Mflv_2786|M.gilvum_PYR-GCK PGNVSSRTVVTMLVVLSSALDDAMREGLVARNVARLVKRPA-VEHHEMAT
Mvan_3747|M.vanbaalenii_PYR-1 PGNVSSRTVVTMLVVLSSALDDAMREGLVARNVARLVKRPA-VEHHEMAT
MMAR_4848|M.marinum_M ------WAKLATLRLLRSILDMAREDGRIHINPAQGVSSGR-IPARERHR
MUL_0529|M.ulcerans_Agy99 ------WAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGR-IPERERHR
Rv2659c|M.tuberculosis_H37Rv -----PTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRP
MAB_1723|M.abscessus_ATCC_1997 --------AQKAHQTLVKALGDAMDEGMLDKNVAAVVDKPK-HVAIERQP
TH_3114|M.thermoresistible__bu ------RGRSRYIPMLAGVGPPRTKDRPVYTVRRGNLAATPVLLPSQVAA
: :
MSMEG_5754|M.smegmatis_MC2_155 LNAEQVTQLLAVTD---SHCYG--IAWRLAVLGLRRGEILALRWDAVDFD
MAV_0253|M.avium_104 LTAAQAERLLAATR---NDVFA--AAWRLALMGLRRGEILGLSWDSVDLD
Mflv_2786|M.gilvum_PYR-GCK WTAEQAVRFREHVR---GDRLA--ACWLLTLAGLRRSEVLGLRWSDVDLD
Mvan_3747|M.vanbaalenii_PYR-1 WTAEQAVRFREHVR---GDRLA--ACWLLTLAGLRRSEVLGLRWSDVDLD
MMAR_4848|M.marinum_M YLSATEVAALAHAC---GDQGD--IVTILAFTGLRWSELVGLRVGDIDLK
MUL_0529|M.ulcerans_Agy99 YLTAQEVRMLATAC---GDQGD--VVTILAYTGLRWSEPVGLRVKDIDLT
Rv2659c|M.tuberculosis_H37Rv ATLDELETITKAMP---DPYQA--FVLMAAWLAMRYGELTELRRKDIDLH
MAB_1723|M.abscessus_ATCC_1997 FTFDEARQIIATAIKRNDPWAT--MWAAMFFTGARQGEIIGMEWDRCDLE
TH_3114|M.thermoresistible__bu ILDGCATQNGHVWSGPASGLRDRLLFATLAETGMRLGEALSLRHHDFHLG
. . * .* : .:
MSMEG_5754|M.smegmatis_MC2_155 AGTLAISAARLATAG-------------GATTGAPKTKTSVRTLPMPEDL
MAV_0253|M.avium_104 AGLLTVRANRAPVPG-------------GVEVGSPKTAAGLRTLPMPAEL
Mflv_2786|M.gilvum_PYR-GCK GGTVTIAQGRVVAEGQ------------GTITGDPKSKRSRRALPMPAEV
Mvan_3747|M.vanbaalenii_PYR-1 GGTVTIAQGRVVAEGQ------------GTITGDPKSKRSRRALPMPAEV
MMAR_4848|M.marinum_M ARRLYVRQAAPDVEG-------------RIIVGPPKTRAAVRTVPLPRIV
MUL_0529|M.ulcerans_Agy99 ARRLYVRRAAPEVEG-------------HIVIGPPKTRAGIRTVPLPQVV
Rv2659c|M.tuberculosis_H37Rv GEVARVRR-AVVRVGE------------GFKVTTPKSDAGVRDISIPPHL
MAB_1723|M.abscessus_ATCC_1997 KGLFDFSWQLQQLPPELPRGFKHRPCHLSLAWTKPKTKAGARVAPMTKPL
TH_3114|M.thermoresistible__bu TGATPYIEVGTRQDHP---------------RGARGKTLHGRRIYIGDDL
. * : :
MSMEG_5754|M.smegmatis_MC2_155 TAALRRVRKRQKEYRLKLGSKWTDSGYVVVDEFG----VAPYPDTLTAAW
MAV_0253|M.avium_104 TVAMKQARKQQRERRLALGSKWVESGLVVVGEDG----APPHPDTLSHVW
Mflv_2786|M.gilvum_PYR-GCK LAALRAFRLRQSEERLAIGSEYPDTGLVAVNVIG----LPIRPETYSGEF
Mvan_3747|M.vanbaalenii_PYR-1 LAALRVFRLRQSEERLAIGSEYPDTGLVAVNVIG----LPIRPETYSGEF
MMAR_4848|M.marinum_M IDALKPRIENRSTKEQAITS--PNGGFLRSNNWR----RHTH-------W
MUL_0529|M.ulcerans_Agy99 VDIFKGRITGQAPDQPAVTS--TNGAMLRSNNWR----RHTH-------W
Rv2659c|M.tuberculosis_H37Rv IPAIEDHLHKHVNPG------RESLLFPSVNDPN----RHLAPSALYRMF
MAB_1723|M.abscessus_ATCC_1997 QAIMEAYAKTDTGPN--------PHGLVWRHPDG----HPISPTDASDAW
TH_3114|M.thermoresistible__bu EALYSSYVWHLVDHGADLAMPNLDTHFVFVNLVAGERFAPMRAETVYAKV
MSMEG_5754|M.smegmatis_MC2_155 RKTLANAG---LPHVRLHDARHSCATLMHLSGVPTVVIAAWLGHQDPGFT
MAV_0253|M.avium_104 AETIAAHK---LPAVRLHDARHTCATLMHQDGVPLAVISAWLGHTNAAFT
Mflv_2786|M.gilvum_PYR-GCK MRHAKDAG---VPLIRLHDVRHTAATMLLDRGTTPSATAKWLGH-DPAIT
Mvan_3747|M.vanbaalenii_PYR-1 MRHAKDAG---VPLIRLHDVRHTAATMLLDRGTTPSATAKWLGH-DPAIT
MMAR_4848|M.marinum_M NKALKKTG---LAPLTIHDLRHTYASLARKSGADLRYVQKTMGHSTPTVT
MUL_0529|M.ulcerans_Agy99 NKALKSTD---LAPLTIHDLRHTYASLARKSGADLRYVQKTMGHSTPTVT
Rv2659c|M.tuberculosis_H37Rv YKARKAAG---RPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAA
MAB_1723|M.abscessus_ATCC_1997 RALVKAAD---VPYRSMHSARHTTATLLNNAGVSQETRMKVVGH-SSAVA
TH_3114|M.thermoresistible__bu DSLTRRSNGVLPEDWTPHWLRHTHATALLLSGAPPHVVMRRLGHADIQTT
* **: * *. :** :
MSMEG_5754|M.smegmatis_MC2_155 LRTYAHSNHDALADAAAMLGSITTGKKK--EAK------------
MAV_0253|M.avium_104 LATYGHSSDDSLAAAAQRLDALTGGKATPAEAK------------
Mflv_2786|M.gilvum_PYR-GCK LRVYGHVYDGALAAAGDTLLRGH----------------------
Mvan_3747|M.vanbaalenii_PYR-1 LRVYGHVYDGALAAAGDTLLRGH----------------------
MMAR_4848|M.marinum_M ANIYSDLYSDELDHVATNLDRLNDVAKDQAN-GQEPDTPKHP---
MUL_0529|M.ulcerans_Agy99 ANIYSDLYADELDQVATNLDQLHATEIQTPTTGQEPDEPNQPSSA
Rv2659c|M.tuberculosis_H37Rv LR-YQHAAKGRDREIAALLSKLAENQEM-----------------
MAB_1723|M.abscessus_ATCC_1997 QQIYVHVDHEPARAALSNLNELLS---------------------
TH_3114|M.thermoresistible__bu LSTYGWVTEDAEMRTVAQWRNYVAGWKGLHHDDTP----------
*