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AGKKGHRGWGWIRQLPSKRYQASYIGPDLIRHKASTTFGARIDAEGWLSQERRSIELDTWTPPAQRAAEV KAKAVTLGEYSTKWIEDRNVKPRTRSSYRDILRLHIEPRLGSMAMKNLTGEVVRSWYAGLGTDYPRRNSH AYGLLHAVCATAVSDGLLQSNPCNIRRAMNPPRRRDPVILAVADIAALAEAIQPRRLRCLVLLAAWCGVR WGEVSELRRKDLSDGCEVLSVSRAVTRRDGVYRVDTPKSGKGRAVVIPPHIREDVINHLAENVESGPESL LFPAARGGHMNDRVFSREYFSDALKAIGRQGVRVHDLRHFAGTQTAQVANLAESMARLGHSTVKASLIYQ GLVTGRDAAIADALSQLAVGES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4364 | - | - | 100% (373) | phage integrase family protein |
| M. vanbaalenii PYR-1 | Mvan_2508 | - | 2e-75 | 42.29% (376) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2335c | - | 5e-06 | 31.48% (108) | hypothetical protein Mb2335c |
| M. gilvum PYR-GCK | Mflv_3899 | - | 3e-69 | 42.42% (356) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2659c | - | 4e-68 | 41.24% (371) | phiRv2 prophage integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4848 | - | 7e-17 | 27.76% (281) | prophage integrase |
| M. avium 104 | MAV_1484 | - | 5e-67 | 40.98% (366) | integrase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2517 | - | 2e-07 | 26.46% (257) | PUTATIVE putative site-specific recombinase, phage integrase |
| M. ulcerans Agy99 | MUL_0529 | - | 8e-17 | 25.69% (362) | prophage integrase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4848|M.marinum_M ---MAGSVPRG--IRKRTNSAGQARYQVRYLVRDPNSPSGWVETSSTFAT
MUL_0529|M.ulcerans_Agy99 ---MAGNTPRG--IRKRLNAAGEPRYQVRYLIRDPDAPSGWVETSATFPT
Mvan_4364|M.vanbaalenii_PYR-1 ---MAGKKGHR--GWGWIRQLPSKRYQASYIGPDLIR----HKASTTFGA
MAV_1484|M.avium_104 -----------------MRQLPSGRWQASYLHNGVV-----FKALATFPT
Mflv_3899|M.gilvum_PYR-GCK MARGTGRKDRAPGTFGSVDKLATG-YRARYFGPDGRR----HKAPVLFLT
Rv2659c|M.tuberculosis_H37Rv MTQ-TGKRQRR--KFGRIRQFNSGRWQASYTGPDGRV----YIAPKTFNA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
TH_2517|M.thermoresistible__bu ------------------------------------------LESVQYPL
MMAR_4848|M.marinum_M MREARAFKADRDGEAAIGA--------------RRFDPRLGRASLSAIWT
MUL_0529|M.ulcerans_Agy99 LREAKAFKSERDNEAALGA--------------RRFDPRLGRTPLSRIWT
Mvan_4364|M.vanbaalenii_PYR-1 RIDAEGWLSQERRSIELDT-----WTPPAQRAAEVKAKAVTLGEYSTKWI
MAV_1484|M.avium_104 KSSAGHWLQAEEDLIDLDRRRPGEWTPPAERAARRQAEKLTLRTYAKTWL
Mflv_3899|M.gilvum_PYR-GCK KTDARAWLAQRHSEIVAQQ-----WTPPN----AVEVPKTTFTEYADQWL
Rv2659c|M.tuberculosis_H37Rv KIDAEAWLTDRRREIDRQL-----WSPASG---QEDRPGAPFGEYAEGWL
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
TH_2517|M.thermoresistible__bu VNTWRTWQFAQS--------------------------------------
MMAR_4848|M.marinum_M QYSASKQPAVSPKTWSGYAQHWELRISPRFGHVPVDEISRKDVQQFIGGL
MUL_0529|M.ulcerans_Agy99 QFSDSKKPAVSPKTWSGYNQHWELRIKPRFGHVPVDEITRADVRAFVDGL
Mvan_4364|M.vanbaalenii_PYR-1 EDR-----NVKPRTRSSYRDILRLHIEPRLGSMAMKNLTGEVVRSWYAGL
MAV_1484|M.avium_104 DNKT----KLARRTRDNYQGHLDNHVLPALGDLGLADITPEHVRTWFAGL
Mflv_3899|M.gilvum_PYR-GCK LTRQVAGRPLKDRTREHYQALLDDHITATFGALPLASITADDVRQWYART
Rv2659c|M.tuberculosis_H37Rv KQ-----RGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATT
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
TH_2517|M.thermoresistible__bu -----------LSKRTVDERVATVTRMANWCQTSPESATSEQIAEWLA-A
MMAR_4848|M.marinum_M TVG-PWAKLATLRLLRSILDMAREDGRIHINPAQGVSSGRIPARER-HRY
MUL_0529|M.ulcerans_Agy99 TVG-PWAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGRIPERER-HRY
Mvan_4364|M.vanbaalenii_PYR-1 GTDYPRRNSHAYGLLHAVCATAVSDGLLQSNPCNIR-RAMNPPRRRDPVI
MAV_1484|M.avium_104 GNEHETRNAQAYAVLNGVFNTAVADDLIDRNPCRIRGAAQVKHARRSVVL
Mflv_3899|M.gilvum_PYR-GCK LTDKPTMRSHAYGLLRTILATAVSDGKISVNPCSIR-GAGTAKRVHKVRP
Rv2659c|M.tuberculosis_H37Rv AVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRIS-GASTARRVHKIRP
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
TH_2517|M.thermoresistible__bu GDWMPRTRWTYHRALSAWFTWLQLQGHRLDNPMLRLGDPKRP--KSVPRP
MMAR_4848|M.marinum_M LSATEVAALAHAC--GDQGDIVTILAFTGLRWSELVGLRVGDIDLKARRL
MUL_0529|M.ulcerans_Agy99 LTAQEVRMLATAC--GDQGDVVTILAYTGLRWSEPVGLRVKDIDLTARRL
Mvan_4364|M.vanbaalenii_PYR-1 LAVADIAALAEAIQPRRLRCLVLLAAWCGVRWGEVSELRRKDLSDGCEVL
MAV_1484|M.avium_104 LDATQLTALAEKM-PDDARLGVLLAGWCGLRKGEVFALRRGDVAADGSSV
Mflv_3899|M.gilvum_PYR-GCK ATVGEIGTIADAM-PAQWSLMVLLAAWLAMRFGELTELRRKDIDLADEVV
Rv2659c|M.tuberculosis_H37Rv ATLDELETITKAM-PDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVA
Mb2335c|M.bovis_AF2122/97 --------------------------------------------------
TH_2517|M.thermoresistible__bu LSNADVARLLTTRMHTRTRAMVLLATFEGLRTFEIAKVRG----------
MMAR_4848|M.marinum_M YVRQAAPDVEGRIIVGPPKTRAAVRTVPLPRIVIDALKPRIENRS---TK
MUL_0529|M.ulcerans_Agy99 YVRRAAPEVEGHIVIGPPKTRAGIRTVPLPQVVVDIFKGRITGQA---PD
Mvan_4364|M.vanbaalenii_PYR-1 SVSRAVTRRDGVYRVDTPKSGKGR-AVVIPPHIREDVINHLAENVESGPE
MAV_1484|M.avium_104 RIERSVTYREGRFEVGPTKTRESRRVVSVPPHVRPAVLEHLQRHVADGDD
Mflv_3899|M.gilvum_PYR-GCK RVRRAVVRTDDGFKVTTPKSDAGIRDIAIPPHLIPPIEAHLSQHVGAKAD
Rv2659c|M.tuberculosis_H37Rv RVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRE
Mb2335c|M.bovis_AF2122/97 --------MTGAGIVETTTN--RVRHVPVPEPVSERLRDELPTEP----N
TH_2517|M.thermoresistible__bu ---------EHFDLVSRTMTVTGKGGITATLPLHHRVVEHAYRMP---RK
: . . : . : . . .
MMAR_4848|M.marinum_M EQAITSPN--GGFLRSNNWRRHTHWNKALKKTGLAPLTIHDLRHTYASLA
MUL_0529|M.ulcerans_Agy99 QPAVTSTN--GAMLRSNNWRRHTHWNKALKSTDLAPLTIHDLRHTYASLA
Mvan_4364|M.vanbaalenii_PYR-1 SLLFPAAR--GGHMNDRVFSR-EYFSDALKAIGRQGVRVHDLRHFAGTQT
MAV_1484|M.avium_104 ALVFVEPS--TGSFAGEKRFR-TAWESARAAIGQPDMHFHDLRHAAGVMA
Mflv_3899|M.gilvum_PYR-GCK ALLFPAVG--GGHLAPATLYR-RFYT-ARERANRKDLRWHDLRHSGAVLA
Rv2659c|M.tuberculosis_H37Rv SLLFPSVNDPNRHLAPSALYR-MFYK-ARKAAGRPDLRVHDLRHSGAVLA
Mb2335c|M.bovis_AF2122/97 ALVFPSYR--GGHLPIEEYRR--AFDKGCKAVGIADLVPHGLRHTTASLA
TH_2517|M.thermoresistible__bu GYWFPGRN--GGHQRRESVGQ--TIKEAITRAG-AVGSAHQLRHWFGTAL
. : . . * *** .
MMAR_4848|M.marinum_M RKSGADLRYVQKTMGHSTPTVTANIYSDLYSDELDHVATNLDRLNDVAKD
MUL_0529|M.ulcerans_Agy99 RKSGADLRYVQKTMGHSTPTVTANIYSDLYADELDQVATNLDQLHATEIQ
Mvan_4364|M.vanbaalenii_PYR-1 AQV-ANLAESMARLGHSTVKASL-IYQGLVTGRDAAIADALSQLAVGES-
MAV_1484|M.avium_104 AQTGATVRELMDRLGHTSPNMSM-RYQHTAEGRAAALADKLSALASTNP-
Mflv_3899|M.gilvum_PYR-GCK AATGATLAELMARLGHSTPQAAL-RYQHAAQGRDRQIAALLSKIAENGGA
Rv2659c|M.tuberculosis_H37Rv ASTGATLAELMQRLGHSTAGAAL-RYQHAAKGRDREIAALLSKLAENQEM
Mb2335c|M.bovis_AF2122/97 ISAGANVKVVQRLLGHATAAMTLDRHGHLLSDDLAGVAGLLVQAIKSAAA
TH_2517|M.thermoresistible__bu VEAGVDLRTVQTLLRHQNLSSTE-IYTQVKEPRRADAIQLLDPFQLDMVA
. : : * . : : *
MMAR_4848|M.marinum_M QAN-GQEPDTPKHP-----
MUL_0529|M.ulcerans_Agy99 TPTTGQEPDEPNQPSSA--
Mvan_4364|M.vanbaalenii_PYR-1 -------------------
MAV_1484|M.avium_104 -------------------
Mflv_3899|M.gilvum_PYR-GCK -------------------
Rv2659c|M.tuberculosis_H37Rv -------------------
Mb2335c|M.bovis_AF2122/97 SLRYSDPDSVAVENISAAS
TH_2517|M.thermoresistible__bu LSASPWKEAA---------