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VDFGRPRDPRIDAAVLRATVELLAETGYPGLLVSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFPVGADTA IPDTGSTADDLREMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGAIGGGLADWLAAAAAR GEARPDVTAAELAETIAGVTLVALLTRPTELDDAWVDRTTRLLLKGISA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5165 | - | - | 100% (189) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4057 | - | 3e-46 | 49.19% (185) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4754 | - | 2e-14 | 35.15% (165) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 2e-44 | 48.65% (185) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4384 | - | 4e-67 | 65.96% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 2e-44 | 48.65% (185) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0260 | - | 4e-21 | 37.84% (185) | transcriptional regulator TetR |
| M. marinum M | MMAR_0340 | - | 2e-79 | 78.42% (190) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2043 | - | 7e-41 | 44.97% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0688 | - | 2e-39 | 44.09% (186) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4780 | - | 6e-79 | 77.89% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1961 | - | 6e-62 | 62.90% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3192c|M.bovis_AF2122/97 --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
Rv3167c|M.tuberculosis_H37Rv --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
MSMEG_2043|M.smegmatis_MC2_155 --------MKAEASPLGKGVGAGRPRDPRIDAAILRATAELLVEIGYANL
TH_0688|M.thermoresistible__bu --------MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNL
MMAR_0340|M.marinum_M -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
MUL_4780|M.ulcerans_Agy99 -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
MAV_5165|M.avium_104 -------------------MDFGRPRDPRIDAAVLRATVELLAETGYPGL
Mflv_4384|M.gilvum_PYR-GCK MPSVVSVTESYVTLSIVMTTDIGRPRNRAIADAVLRATVELLAESSYAEL
Mvan_1961|M.vanbaalenii_PYR-1 ---------------------MGRPRNRAIDDAVLRATVELISESSYAEL
MAB_0260|M.abscessus_ATCC_1997 ------------MSTEESSLGRGRRRSSDIDVKALAAARELLVEQGWEAT
** *. * * *: :*: : .:
Mb3192c|M.bovis_AF2122/97 SLAAVAERAGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAAAGDIAAD
Rv3167c|M.tuberculosis_H37Rv SLAAVAERAGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAAAGDIAAD
MSMEG_2043|M.smegmatis_MC2_155 TMAAVAERAQTTKTALYRRWSSKAELVHEAVFP-AVPTGLVAPAGDIAAD
TH_0688|M.thermoresistible__bu TMSAVAERAGTTKTALYRRWSSKPELVYAATAP-TDPVDTVESSDDVAGI
MMAR_0340|M.marinum_M LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPDTGSPVDD
MUL_4780|M.ulcerans_Agy99 LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-IDAATAVPDTGSPVDD
MAV_5165|M.avium_104 LVSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFP-VGADTAIPDTGSTADD
Mflv_4384|M.gilvum_PYR-GCK SLDAVAARAGTSKPAIYRRWRGKAHLVHEAVFP-LGADTAIPGSGSLEAD
Mvan_1961|M.vanbaalenii_PYR-1 SLDAIAARAGTSKPAIYRRWRGKAHLVHEAVFP-VDATIEIPRTGSLHGD
MAB_0260|M.abscessus_ATCC_1997 TMVAIADRASVGKPALYRRWPSRAHLVFEAVFGWTAPTPEMSAAAGVTDW
: *:* ** . *.*:**** .:..**. *. . : .
Mb3192c|M.bovis_AF2122/97 IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-V
Rv3167c|M.tuberculosis_H37Rv IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAA-V
MSMEG_2043|M.smegmatis_MC2_155 VHAMIAAARDVFTSPVVRAALPGLIADVSADANLNARVMERFTGVFAA-V
TH_0688|M.thermoresistible__bu VRALIERNRQITATPAARAAMPGLLVDMAADPRLHRGLLGRVGSLVEA-L
MMAR_0340|M.marinum_M LREMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEIFGHGL
MUL_4780|M.ulcerans_Agy99 LREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHGL
MAV_5165|M.avium_104 LREMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGAIGGGL
Mflv_4384|M.gilvum_PYR-GCK VREMTRRTLAVLSTPAALAALPGLVGEMASDPTLHTALLERFGDILVRGL
Mvan_1961|M.vanbaalenii_PYR-1 VREMLRRTLAVLSTPAARAALPGLVGEMASDPTLHAALLERFADVLVRDL
MAB_0260|M.abscessus_ATCC_1997 VRQSCSYTAELFERPDVIAAAPALLGQMRTDPELGQALWGSFGATGAGLL
:: . * . ** *.*: :: :*. * : . :
Mb3192c|M.bovis_AF2122/97 RMRLREAVD-RGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD---DAW
Rv3167c|M.tuberculosis_H37Rv RMRLREAVD-RGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD---DAW
MSMEG_2043|M.smegmatis_MC2_155 RERIVDGIA-RGEVHAAVSPDRLVEIIGGATMLRLLLVSDENLD---DEW
TH_0688|M.thermoresistible__bu RRRLAEAAG-RGEVQSGVDADRLTELIGGSVMFRMVLHPDEPIT---ERW
MMAR_0340|M.marinum_M TTWLDNAAA-RGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAW
MUL_4780|M.ulcerans_Agy99 TTWLDNAAA-RGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVGDAW
MAV_5165|M.avium_104 ADWLAAAAA-RGEARPDVTAAELAETIAGVTLVALLTRPTELD----DAW
Mflv_4384|M.gilvum_PYR-GCK TEFLESAVR-RGDVRPDVTASDLAEAVAGMTLLALLTRGTAVD----EVW
Mvan_1961|M.vanbaalenii_PYR-1 NNYLDSAVR-RGEVRRGVTAVELAEAVTGMTLLALITRGANVD----DAW
MAB_0260|M.abscessus_ATCC_1997 SRVMRAQQPEIGQEEAQERANAIMFMIIGANMLARQLLPGEHA----EAV
: *: . . : : * :. :
Mb3192c|M.bovis_AF2122/97 VDQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv VDQTTAIVVRGVHRAAPGGSVV
MSMEG_2043|M.smegmatis_MC2_155 VHQTAAIVIHGVTVGR------
TH_0688|M.thermoresistible__bu ADEVAAILIRGVTKEG------
MMAR_0340|M.marinum_M IDRTTTLLLKGIRKGTPQ----
MUL_4780|M.ulcerans_Agy99 IDRTTTLLLKGIRKGTPQ----
MAV_5165|M.avium_104 VDRTTRLLLKGISA--------
Mflv_4384|M.gilvum_PYR-GCK LDRTARLITKGISA--------
Mvan_1961|M.vanbaalenii_PYR-1 IERTAHLITKGISS--------
MAB_0260|M.abscessus_ATCC_1997 IKHLPELLTEPGESPGSVRPSG
.. . :: .