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VRAAREIFSELGYDAATFQAIAVRADLTRPAINHYFSSKRVLWAEVVEQTYASVVGVGIARAHEQTSLLN RLMAFLSVATQVDTDDRSAAAFLVTSVLESQRHPELADDDHDSLTNSRAFVSWAVNDAVARGELSADTDV NHLVEMLVAVVWGMGFYAGFVGDRSDFGAVMHKLELLLANKLWNLGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0103 | - | - | 100% (187) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2776 | - | 2e-18 | 33.33% (162) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1870 | - | 4e-06 | 29.53% (149) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 1e-51 | 53.01% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0744 | - | 2e-83 | 80.75% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 1e-51 | 53.01% (183) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3462c | - | 5e-07 | 29.41% (153) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0355 | - | 4e-49 | 53.01% (183) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5151 | - | 1e-47 | 50.54% (186) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0092 | - | 3e-70 | 68.31% (183) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1278 | - | 5e-48 | 62.76% (145) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4765 | - | 3e-49 | 53.01% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MMAR_0355|M.marinum_M --------------------------------------------------
MUL_4765|M.ulcerans_Agy99 --------------------------------------------------
MAV_5151|M.avium_104 --------------------------------------------------
Mvan_0103|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155 --------------------------------------------------
TH_1278|M.thermoresistible__bu --------------------------------------------------
MAB_3462c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MMAR_0355|M.marinum_M -------------------MQLTASRGPGRPPAAKADDTRRRIVGAAREV
MUL_4765|M.ulcerans_Agy99 ------------------MMQLTASRGPGRPPAAKADDTRRRIVGAAREV
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
Mvan_0103|M.vanbaalenii_PYR-1 -------------------------------------------MRAAREI
Mflv_0744|M.gilvum_PYR-GCK -------------MWHNFNVPYTASRGPGRPPAAKAAETRERILRAAREV
MSMEG_0092|M.smegmatis_MC2_155 -------------------MAHIASRGPGRPPAAKAAETRERILSAAREV
TH_1278|M.thermoresistible__bu --------------------------------------------------
MAB_3462c|M.abscessus_ATCC_199 ------------MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLHAADDL
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MMAR_0355|M.marinum_M FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MUL_4765|M.ulcerans_Agy99 FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
Mvan_0103|M.vanbaalenii_PYR-1 FSELGYDAATFQAIAVRADLTRPAINHYFSSKRVLWAEVVEQTYASVVGV
Mflv_0744|M.gilvum_PYR-GCK FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE
MSMEG_0092|M.smegmatis_MC2_155 FSELGYDAATFQAIAIRADLTRPAINHYFGSKRVLYREVVEQTNATVIAA
TH_1278|M.thermoresistible__bu ---------------------------------VLYQEVVQQTNSLVVAE
MAB_3462c|M.abscessus_ATCC_199 LVARGYAGVTMEGIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAACQLDP
: :*. : :
Mb0149|M.bovis_AF2122/97 GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
Rv0144|M.tuberculosis_H37Rv GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
MMAR_0355|M.marinum_M GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MUL_4765|M.ulcerans_Agy99 GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MAV_5151|M.avium_104 GIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWN
Mvan_0103|M.vanbaalenii_PYR-1 GIARAHEQTSLLNRLMAFLSVATQVDTDDRSAAAFLVTSVLESQRHPELA
Mflv_0744|M.gilvum_PYR-GCK AIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELI
MSMEG_0092|M.smegmatis_MC2_155 GVARAREATSLLGRLSAFFAAAMDAESADRSSAAFLVTSVLESQRHPDLV
TH_1278|M.thermoresistible__bu GMERAKRETTLLGRLSAFFTAAMQAESEDRSTAAFLVISVLESQRHPELT
MAB_3462c|M.abscessus_ATCC_199 -----PDLGGLEADLRHHLSATAQFLAADDAGAVFRALIGQSQHDGQLAD
* * . : . : : :.* ..:
Mb0149|M.bovis_AF2122/97 RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
Rv0144|M.tuberculosis_H37Rv RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
MMAR_0355|M.marinum_M RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY
MUL_4765|M.ulcerans_Agy99 RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY
MAV_5151|M.avium_104 TAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVGLY
Mvan_0103|M.vanbaalenii_PYR-1 DDDHDSLTNSRAFVSWAVNDAVARGELSADTDVNHLVEMLVAVVWGMGFY
Mflv_0744|M.gilvum_PYR-GCK NDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMGFY
MSMEG_0092|M.smegmatis_MC2_155 SEEQDALLNSRKFVAWAVNDAIERGELTTDTDIPAIVEMLVAVMWGMGFY
TH_1278|M.thermoresistible__bu IDEFDALKNSRAFVTWAVNDAIERGELTTNTDVSKIVEMLVAVLWGMGFY
MAB_3462c|M.abscessus_ATCC_199 DFRGRYLREQQARDQIPIARAVARGELPADVDVAHVAEQLVAPLY---YR
: : : *: :**: :. * :.* *: :
Mb0149|M.bovis_AF2122/97 IGFVGSYQRMATITDSFQQLLAGTLWRPPT
Rv0144|M.tuberculosis_H37Rv IGFVGSYQRMATITDSFQQLLAGTLWRPPT
MMAR_0355|M.marinum_M AGFVGSYRDMENILDTLCKMMAGTLWKPRS
MUL_4765|M.ulcerans_Agy99 AGFVGSYRDMENILDTLCKMMAGTLWKPRS
MAV_5151|M.avium_104 AGYVETYQEMLAVTGMLRQLLEGALWRPGS
Mvan_0103|M.vanbaalenii_PYR-1 AGFVGDRSDFGAVMHKLELLLANKLWNLGE
Mflv_0744|M.gilvum_PYR-GCK AGFVGDRSDLSAVVHKLELLLAGKLWNVAD
MSMEG_0092|M.smegmatis_MC2_155 AGYVGRSEELAAIVDKFEMLMANKLWQLRD
TH_1278|M.thermoresistible__bu AGYVGRQEDLKTVVEQFELLLANKLWQLKS
MAB_3462c|M.abscessus_ATCC_199 VIVTGETVDAAFVDRIVEDFLRRRE-----
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