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M. thermoresistible (build 8) TH_1278 ()

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY)
coordinates: 2435086 - 2435529
length: 148

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1278-100% (148)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY)
M. thermoresistible (build 8)TH_3831-3e-2241.73% (139) PUTATIVE putative transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0149-4e-4052.78% (144) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0744-1e-4966.21% (145) TetR family transcriptional regulator
M. tuberculosis H37RvRv0144-4e-4052.78% (144) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0355-1e-3347.26% (146) TetR family transcriptional regulator
M. avium 104MAV_5151-3e-3245.45% (143) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_0092-8e-5872.60% (146) transcriptional regulatory protein
M. ulcerans Agy99MUL_4765-7e-3447.26% (146) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0103-5e-4862.76% (145) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_1278|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0103|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0149|M.bovis_AF2122/97            MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv         MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MMAR_0355|M.marinum_M               --------------------------------------------------
MUL_4765|M.ulcerans_Agy99           --------------------------------------------------
MAV_5151|M.avium_104                --------------------------------------------------
                                                                                      

TH_1278|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155      -------------------MAHIASRGPGRPPAAKAAETRERILSAAREV
Mflv_0744|M.gilvum_PYR-GCK          -------------MWHNFNVPYTASRGPGRPPAAKAAETRERILRAAREV
Mvan_0103|M.vanbaalenii_PYR-1       -------------------------------------------MRAAREI
Mb0149|M.bovis_AF2122/97            ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv         ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MMAR_0355|M.marinum_M               -------------------MQLTASRGPGRPPAAKADDTRRRIVGAAREV
MUL_4765|M.ulcerans_Agy99           ------------------MMQLTASRGPGRPPAAKADDTRRRIVGAAREV
MAV_5151|M.avium_104                -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
                                                                                      

TH_1278|M.thermoresistible__bu      ---------------------------------VLYQEVVQQTNSLVVAE
MSMEG_0092|M.smegmatis_MC2_155      FSELGYDAATFQAIAIRADLTRPAINHYFGSKRVLYREVVEQTNATVIAA
Mflv_0744|M.gilvum_PYR-GCK          FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE
Mvan_0103|M.vanbaalenii_PYR-1       FSELGYDAATFQAIAVRADLTRPAINHYFSSKRVLWAEVVEQTYASVVGV
Mb0149|M.bovis_AF2122/97            FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv         FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MMAR_0355|M.marinum_M               FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MUL_4765|M.ulcerans_Agy99           FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MAV_5151|M.avium_104                FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
                                                                     .*: **: :*   ::  

TH_1278|M.thermoresistible__bu      GMERAKRETTLLGRLSAFFTAAMQAESEDRSTAAFLVISVLESQRHPELT
MSMEG_0092|M.smegmatis_MC2_155      GVARAREATSLLGRLSAFFAAAMDAESADRSSAAFLVTSVLESQRHPDLV
Mflv_0744|M.gilvum_PYR-GCK          AIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELI
Mvan_0103|M.vanbaalenii_PYR-1       GIARAHEQTSLLNRLMAFLSVATQVDTDDRSAAAFLVTSVLESQRHPELA
Mb0149|M.bovis_AF2122/97            GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
Rv0144|M.tuberculosis_H37Rv         GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
MMAR_0355|M.marinum_M               GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MUL_4765|M.ulcerans_Agy99           GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MAV_5151|M.avium_104                GIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWN
                                    .: .*    :*: :* ...  * ..::   : :**:   ********:  

TH_1278|M.thermoresistible__bu      IDEFDALKNSRAFVTWAVNDAIERGELTTNTDVSKIVEMLVAVLWGMGFY
MSMEG_0092|M.smegmatis_MC2_155      SEEQDALLNSRKFVAWAVNDAIERGELTTDTDIPAIVEMLVAVMWGMGFY
Mflv_0744|M.gilvum_PYR-GCK          NDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMGFY
Mvan_0103|M.vanbaalenii_PYR-1       DDDHDSLTNSRAFVSWAVNDAVARGELSADTDVNHLVEMLVAVVWGMGFY
Mb0149|M.bovis_AF2122/97            RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
Rv0144|M.tuberculosis_H37Rv         RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
MMAR_0355|M.marinum_M               RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY
MUL_4765|M.ulcerans_Agy99           RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY
MAV_5151|M.avium_104                TAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVGLY
                                      : *::  :* *:  .* **: :**: :. *   :.* *: :: *:*:*

TH_1278|M.thermoresistible__bu      AGYVGRQEDLKTVVEQFELLLANKLWQLKS
MSMEG_0092|M.smegmatis_MC2_155      AGYVGRSEELAAIVDKFEMLMANKLWQLRD
Mflv_0744|M.gilvum_PYR-GCK          AGFVGDRSDLSAVVHKLELLLAGKLWNVAD
Mvan_0103|M.vanbaalenii_PYR-1       AGFVGDRSDFGAVMHKLELLLANKLWNLGE
Mb0149|M.bovis_AF2122/97            IGFVGSYQRMATITDSFQQLLAGTLWRPPT
Rv0144|M.tuberculosis_H37Rv         IGFVGSYQRMATITDSFQQLLAGTLWRPPT
MMAR_0355|M.marinum_M               AGFVGSYRDMENILDTLCKMMAGTLWKPRS
MUL_4765|M.ulcerans_Agy99           AGFVGSYRDMENILDTLCKMMAGTLWKPRS
MAV_5151|M.avium_104                AGYVETYQEMLAVTGMLRQLLEGALWRPGS
                                     *:*     :  :   :  :: . **.