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MPSEPPRRRNAAFTRAAILQSAIQHFARAGYDGAGVRDIATDAGVTAMLVNRYFGSKEKLFAEAVETSFA TPVFIASESEDLARDIAAALAVHSAPGAESVSAFLIMLRSVSNPAAVRIVRAALARHAGRRLSDQLPEPG RLLRSDVALAVMSGVLLMRQVIGTRALSRSSADELETLLESVFSAVFDTPLDSRGDAPRTGED
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0297 | - | - | 100% (203) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0253 | - | 3e-12 | 29.74% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0744 | - | 4e-10 | 30.61% (196) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 7e-12 | 29.38% (177) | hypothetical protein Mb1711c |
| M. tuberculosis H37Rv | Rv1685c | - | 7e-12 | 29.38% (177) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 5e-05 | 24.60% (187) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2885 | - | 3e-13 | 26.34% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3397 | - | 6e-15 | 31.43% (175) | putative regulatory protein |
| M. avium 104 | MAV_3088 | - | 3e-11 | 29.38% (160) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1700 | - | 2e-15 | 34.52% (168) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 3e-08 | 27.03% (185) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4899 | - | 8e-11 | 32.22% (180) | hypothetical protein MUL_4899 |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 2e-11 | 31.74% (167) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2885|M.abscessus_ATCC_1997 ---------MPPEPRRSDATRAAILEAAQEHFASVGYEKATIRAIAGTAG
MSMEG_1700|M.smegmatis_MC2_155 ---------MR---RSAAETKSVILAAARERFAADGYERATIRSIAADAS
MUL_4899|M.ulcerans_Agy99 ---------MPVKTRDATATRSAILDAAQSQFGENGFERTTIRSVAKAAG
MMAR_3397|M.marinum_M ----------MGRRRGNPDTRNAIVTTARRLFAESGYEQTSVRDIASAAG
Mb1711c|M.bovis_AF2122/97 MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
Rv1685c|M.tuberculosis_H37Rv MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
MAV_3088|M.avium_104 MTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAAAAG
Mvan_3298|M.vanbaalenii_PYR-1 MTTN-ADRKRPGRPPGTSDTRDRILECARELFARNGITNTSIRSIAAGAG
TH_3542|M.thermoresistible__bu -----------------------VLAAAKRRFAQDGYEKTTLRAIARDAH
Mflv_0297|M.gilvum_PYR-GCK ------MPSEPPRRRNAAFTRAAILQSAIQHFARAGYDGAGVRDIATDAG
MLBr_02568|M.leprae_Br4923 -------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQ
:: * *. * : : :* *
MAB_2885|M.abscessus_ATCC_1997 IDPSLVMRYYGNKGKLFAAAANFDLCLPELSAVSH----EELGTVIVQHF
MSMEG_1700|M.smegmatis_MC2_155 IDPSMVMRYFGNKERLFAAAAEFDLELPDLALVPR----EEIGATLAGHF
MUL_4899|M.ulcerans_Agy99 VDPALVMHYFGSKAGLFTAATRFDIKFPDLSGIPM----DRIADALLPNF
MMAR_3397|M.marinum_M VDPALIRHYFGSKAELFRSIVGWPFEADAMSALILSGDRDELGARLTRVF
Mb1711c|M.bovis_AF2122/97 VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLL
Rv1685c|M.tuberculosis_H37Rv VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLL
MAV_3088|M.avium_104 VDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVPVDDLGYALPSML
Mvan_3298|M.vanbaalenii_PYR-1 VDPALVHHYFGTKTQLFAAAIEIPIDPMSIIGPLKEVPVDQLGRALPSLL
TH_3542|M.thermoresistible__bu VDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGDD-GDVGTRMVRVY
Mflv_0297|M.gilvum_PYR-GCK VTAMLVNRYFGSKEKLFAEAVETSFATPVFIASESEDLARDIAAALAVHS
MLBr_02568|M.leprae_Br4923 ISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTI
: :: :*.* ** : :
MAB_2885|M.abscessus_ATCC_1997 LERWEV---DDTMVALLRAAVSNEEARLRMVEIFTDQSLPAFEELL--TD
MSMEG_1700|M.smegmatis_MC2_155 LERWER---DEALLILLRAGVTNEAVAERMRTIFAAQLAPVIAKLTGGAP
MUL_4899|M.ulcerans_Agy99 LRVWGP---RGAFLPLLRAAATNRDAADALVEVFVDRVGPALSAIV--PD
MMAR_3397|M.marinum_M LEAWERPESRAPLLAILRGAATHEESTTLVRQFFQDQMYPQLAQPLP-GP
Mb1711c|M.bovis_AF2122/97 LPIWDS-ELGAGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPG
Rv1685c|M.tuberculosis_H37Rv LPIWDS-ELGAGLIATLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPG
MAV_3088|M.avium_104 LPLWDS-EVGAAFIATLRSILAGEEISLFRTFIQDVIGVEVGPRVDNPAG
Mvan_3298|M.vanbaalenii_PYR-1 LPLWDS-ELGKGFIATLRSILAGSDVSMVRSFLQDLIATEVGGRVDDPPG
TH_3542|M.thermoresistible__bu LQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLGGGE
Mflv_0297|M.gilvum_PYR-GCK APGAES---VSAFLIMLRSVSNPAAVRIVRAALARHAGRRLSDQLP--EP
MLBr_02568|M.leprae_Br4923 VSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGT
:
MAB_2885|M.abscessus_ATCC_1997 HAAERAALIGGQMIGFAVCRYILRLSPVIE--MTHQDIVNWMAPIVQQYI
MSMEG_1700|M.smegmatis_MC2_155 DAPVRASLAASQVLGMALCRYVLAFPPLVD--MSRDGVVAWIGPTLQRYL
MUL_4899|M.ulcerans_Agy99 RGPERAALVAAQMVGVATARYVIGLPPLLH--MDDEELIRWLRPVIVHYL
MMAR_3397|M.marinum_M DTELRIDLAMAQLLGIAYLRHVLRLEPIAS--TPLEEVVARVTPTIIAHL
Mb1711c|M.bovis_AF2122/97 TGKIRTQFVASQLMGVVMARYIVRIEPFAS--LPAEQIVQTIAPNLQRYL
Rv1685c|M.tuberculosis_H37Rv TGKIRTQFVASQLMGVVMARYIVRIEPFAS--LPAEQIVQTIAPNLQRYL
MAV_3088|M.avium_104 SGVIRIQFVASQLVGVVMARYILELEPFAS--LPPEQIAATIAPNLQRYL
Mvan_3298|M.vanbaalenii_PYR-1 SGRVRVQFVASQLVGIVMARYILELEPFKS--LPVEQIVDTVAPNLQRYL
TH_3542|M.thermoresistible__bu QARLRAELAATGLVGTAMLRYIMRVPPLAE--LSTEEVVRMLAPTVNRYL
Mflv_0297|M.gilvum_PYR-GCK GRLLRSDVALAVMSGVLLMRQVIGTRALSR--SSADELETLLESVFSAVF
MLBr_02568|M.leprae_Br4923 RSS-RPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGL
* : * . : : . :
MAB_2885|M.abscessus_ATCC_1997 DTPAP------------
MSMEG_1700|M.smegmatis_MC2_155 VG---------------
MUL_4899|M.ulcerans_Agy99 TDPAP------------
MMAR_3397|M.marinum_M EPSRLDKAADR------
Mb1711c|M.bovis_AF2122/97 TGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv TGELPDDLAP-------
MAV_3088|M.avium_104 TGDLPDGLAP-------
Mvan_3298|M.vanbaalenii_PYR-1 TGELPQFSGD-------
TH_3542|M.thermoresistible__bu TADADELGLPSSLTAGS
Mflv_0297|M.gilvum_PYR-GCK DTPLDSRGDAPRTGED-
MLBr_02568|M.leprae_Br4923 KGAPADRDFGPSIVAG-