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MQLTASRGPGRPPAAKADDTRRRIVGAAREVFSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREV VVQTNELVVAAGVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELRRSDHDAVAA TREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFYAGFVGSYRDMENILDTLCKMMAGTLWKPR S*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4765 | - | - | 100% (212) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4876 | - | 1e-14 | 26.77% (198) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4875 | - | 2e-10 | 25.43% (173) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 1e-80 | 70.33% (209) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0744 | - | 2e-60 | 55.88% (204) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 1e-80 | 70.33% (209) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 3e-05 | 32.81% (64) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 3e-08 | 35.38% (65) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0355 | - | 1e-116 | 100.00% (211) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5151 | - | 6e-64 | 56.31% (206) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0092 | - | 1e-61 | 56.80% (206) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1278 | - | 1e-33 | 47.26% (146) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. vanbaalenii PYR-1 | Mvan_0103 | - | 5e-49 | 53.01% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0744|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0103|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155 --------------------------------------------------
TH_1278|M.thermoresistible__bu --------------------------------------------------
MUL_4765|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0355|M.marinum_M --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MAV_5151|M.avium_104 --------------------------------------------------
MLBr_00717|M.leprae_Br4923 --------------------------------------------------
MAB_1149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK -------------MWHNFNVPYTASRGPGRPPAAKAAETRERILRAAREV
Mvan_0103|M.vanbaalenii_PYR-1 -------------------------------------------MRAAREI
MSMEG_0092|M.smegmatis_MC2_155 -------------------MAHIASRGPGRPPAAKAAETRERILSAAREV
TH_1278|M.thermoresistible__bu --------------------------------------------------
MUL_4765|M.ulcerans_Agy99 ------------------MMQLTASRGPGRPPAAKADDTRRRIVGAAREV
MMAR_0355|M.marinum_M -------------------MQLTASRGPGRPPAAKADDTRRRIVGAAREV
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
MLBr_00717|M.leprae_Br4923 ---------------------MTTARRRLSP-----EDRRAELLALGAEV
MAB_1149|M.abscessus_ATCC_1997 ----------------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARSL
Mflv_0744|M.gilvum_PYR-GCK FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE
Mvan_0103|M.vanbaalenii_PYR-1 FSELGYDAATFQAIAVRADLTRPAINHYFSSKRVLWAEVVEQTYASVVGV
MSMEG_0092|M.smegmatis_MC2_155 FSELGYDAATFQAIAIRADLTRPAINHYFGSKRVLYREVVEQTNATVIAA
TH_1278|M.thermoresistible__bu ---------------------------------VLYQEVVQQTNSLVVAE
MUL_4765|M.ulcerans_Agy99 FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MMAR_0355|M.marinum_M FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
MLBr_00717|M.leprae_Br4923 FGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAA
MAB_1149|M.abscessus_ATCC_1997 FAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLLDG
:: *: :
Mflv_0744|M.gilvum_PYR-GCK AIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELI
Mvan_0103|M.vanbaalenii_PYR-1 GIARAHEQTSLLNRLMAFLSVATQVDTDDRSAAAFLVTSVLESQRHPELA
MSMEG_0092|M.smegmatis_MC2_155 GVARAREATSLLGRLSAFFAAAMDAESADRSSAAFLVTSVLESQRHPDLV
TH_1278|M.thermoresistible__bu GMERAKRETTLLGRLSAFFTAAMQAESEDRSTAAFLVISVLESQRHPELT
MUL_4765|M.ulcerans_Agy99 GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MMAR_0355|M.marinum_M GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
Mb0149|M.bovis_AF2122/97 GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
Rv0144|M.tuberculosis_H37Rv GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
MAV_5151|M.avium_104 GIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWN
MLBr_00717|M.leprae_Br4923 TNIPPPAGLTMFEEVRVGVLAYMAYHKQNPE--AAWAAYVGLGRSDPVLL
MAB_1149|M.abscessus_ATCC_1997 -ITSSLTSYRSRVRLEQVALALLSYIEERTDGFRILIRDSPPGVSSGTYS
. .: .
Mflv_0744|M.gilvum_PYR-GCK NDEHDSLKNSRRFVSAAVSDAIERG-ELSADTDVTHLVEMLVAVVWGMGF
Mvan_0103|M.vanbaalenii_PYR-1 DDDHDSLTNSRAFVSWAVNDAVARG-ELSADTDVNHLVEMLVAVVWGMGF
MSMEG_0092|M.smegmatis_MC2_155 SEEQDALLNSRKFVAWAVNDAIERG-ELTTDTDIPAIVEMLVAVMWGMGF
TH_1278|M.thermoresistible__bu IDEFDALKNSRAFVTWAVNDAIERG-ELTTNTDVSKIVEMLVAVLWGMGF
MUL_4765|M.ulcerans_Agy99 RSDHDAVAATREFLDTAVRDAIQRG-ELEAGVDASQLAEALLLLLCGVGF
MMAR_0355|M.marinum_M RSDHDAVAATREFLDTAVRDAIQRG-ELEAGVDASQLAEALLLLLCGVGF
Mb0149|M.bovis_AF2122/97 RTENDAVRATREFLVWAVNDAIERG-ELAADVDVSSLAETLLVVLCGVGF
Rv0144|M.tuberculosis_H37Rv RTENDAVRATREFLVWAVNDAIERG-ELAADVDVSSLAETLLVVLCGVGF
MAV_5151|M.avium_104 TAENDSVRIAREFLIRVVNDAIEHG-EVAADIDASALVETLLVVMCGVGL
MLBr_00717|M.leprae_Br4923 GIDDEAKNRQMEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTF
MAB_1149|M.abscessus_ATCC_1997 SLLNDAVSQVSSILAG---DFQRRGLDAEMAPLYAQALVGQVSMTAQWWL
:: : * : : :
Mflv_0744|M.gilvum_PYR-GCK YAG---FVGDRSDLSAVVHKLELLLAGKLWNVAD----------------
Mvan_0103|M.vanbaalenii_PYR-1 YAG---FVGDRSDFGAVMHKLELLLANKLWNLGE----------------
MSMEG_0092|M.smegmatis_MC2_155 YAG---YVGRSEELAAIVDKFEMLMANKLWQLRD----------------
TH_1278|M.thermoresistible__bu YAG---YVGRQEDLKTVVEQFELLLANKLWQLKS----------------
MUL_4765|M.ulcerans_Agy99 YAG---FVGSYRDMENILDTLCKMMAGTLWKPRS----------------
MMAR_0355|M.marinum_M YAG---FVGSYRDMENILDTLCKMMAGTLWKPRS----------------
Mb0149|M.bovis_AF2122/97 YIG---FVGSYQRMATITDSFQQLLAGTLWRPPT----------------
Rv0144|M.tuberculosis_H37Rv YIG---FVGSYQRMATITDSFQQLLAGTLWRPPT----------------
MAV_5151|M.avium_104 YAG---YVETYQEMLAVTGMLRQLLEGALWRPGS----------------
MLBr_00717|M.leprae_Br4923 EVCRQRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIARQPP
MAB_1149|M.abscessus_ATCC_1997 DAR---EPKKEVVAAHIVNLCWHGLKHLEADPQLHEE-------------
: :
Mflv_0744|M.gilvum_PYR-GCK -
Mvan_0103|M.vanbaalenii_PYR-1 -
MSMEG_0092|M.smegmatis_MC2_155 -
TH_1278|M.thermoresistible__bu -
MUL_4765|M.ulcerans_Agy99 -
MMAR_0355|M.marinum_M -
Mb0149|M.bovis_AF2122/97 -
Rv0144|M.tuberculosis_H37Rv -
MAV_5151|M.avium_104 -
MLBr_00717|M.leprae_Br4923 Q
MAB_1149|M.abscessus_ATCC_1997 -