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VTDDVKGDEANKSVDDKNDENKVEAAPEAEAVESTEAVESTEAVEPTGTDPEATDADVTAAAPTRRVEWS RVVAFLVLPALALVLAAGAGYLKWLDDSYRDGSMSVDGNGRPSLAETSVQAARDSTIALLSYAPDTVEQQ LGAARELLTGEFRDSYTSLTNDVVIPGAKEKQIAAIATVPAAASVSVTADEAVVLLFVNQTVTVGPDAPT DTASSVRVTLEKDGDRWLISKFDPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2108 | - | - | 100% (235) | hypothetical protein Mflv_2108 |
| M. gilvum PYR-GCK | Mflv_0645 | - | 8e-44 | 43.42% (228) | hypothetical protein Mflv_0645 |
| M. gilvum PYR-GCK | Mflv_2527 | - | 5e-29 | 38.89% (216) | hypothetical protein Mflv_2527 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1397c | - | 1e-26 | 35.15% (239) | hypothetical protein Mb1397c |
| M. tuberculosis H37Rv | Rv1973 | - | 1e-50 | 60.36% (169) | MCE associated membrane protein |
| M. leprae Br4923 | MLBr_02615 | - | 8e-07 | 25.49% (153) | hypothetical protein MLBr_02615 |
| M. abscessus ATCC 19977 | MAB_4146c | - | 2e-13 | 27.78% (162) | MCE-family protein |
| M. marinum M | MMAR_2889 | - | 2e-50 | 56.06% (198) | Mce associated membrane protein |
| M. avium 104 | MAV_1970 | - | 2e-60 | 58.04% (224) | hypothetical protein MAV_1970 |
| M. smegmatis MC2 155 | MSMEG_0353 | - | 5e-45 | 51.03% (194) | hypothetical protein MSMEG_0353 |
| M. thermoresistible (build 8) | TH_4601 | - | 5e-55 | 55.88% (204) | PUTATIVE putative hypothetical protein Mflv_2108 |
| M. ulcerans Agy99 | MUL_2863 | - | 4e-50 | 56.45% (186) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4597 | - | 3e-77 | 66.38% (232) | hypothetical protein Mvan_4597 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2108|M.gilvum_PYR-GCK MTDDVKG---------DEANKSVDDKNDENK----VEAAPEAEAVESTEA
Mvan_4597|M.vanbaalenii_PYR-1 MSNEKTGTADITEDTTAAADEPATDTEQPAKGTDDAESAADKTGAEETDT
MMAR_2889|M.marinum_M -----------------------------------------MTAVGPPGA
MUL_2863|M.ulcerans_Agy99 -----------------------------------------MTAVSRPGA
Rv1973|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1970|M.avium_104 ---------------MSRLTWPKRSKSAPEDVALDANEVTEVSTTEAPGT
TH_4601|M.thermoresistible__bu -----------------------------------VTATTGIEGSETTGP
MSMEG_0353|M.smegmatis_MC2_155 -----------------------------------------MLAAQEVSE
Mb1397c|M.bovis_AF2122/97 ------------------MTDDVRDVNTETTDATEVAEIDSAAGEAGDSA
MAB_4146c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02615|M.leprae_Br4923 --------------MRNRWRLLAFDVVAPLVAIAALVMIGVVLDWPRWWV
Mflv_2108|M.gilvum_PYR-GCK VES-TEAVEPTGTDPEAT-----DADVTAAA-------------PTRRVE
Mvan_4597|M.vanbaalenii_PYR-1 VDEDAEVTEDADEDAEVTEDDDEDAEVTEDAGEDAEATDDAAVTPKRDGK
MMAR_2889|M.marinum_M GECGDTDTAANGEPPAVVR---------------------------RRLR
MUL_2863|M.ulcerans_Agy99 GECGDTDTAGSGEPPAVVR---------------------------RRLR
Rv1973|M.tuberculosis_H37Rv ------------------------------------------------MS
MAV_1970|M.avium_104 DEAETETDTAADSTGDTTDETSAEPTEGTVGEDEP--------AAEWRVD
TH_4601|M.thermoresistible__bu AEADT---VAGDTSGRS---------------------------------
MSMEG_0353|M.smegmatis_MC2_155 PEAAQPQSDSGPR------------------------------------R
Mb1397c|M.bovis_AF2122/97 TEAFDTDSATESTAQKGQR---------------------------HRDL
MAB_4146c|M.abscessus_ATCC_199 ------------------------------------------------MR
MLBr_02615|M.leprae_Br4923 SACSVLVLLIVEGVGVNFWLLRRDSVTIG----------------TDDDA
Mflv_2108|M.gilvum_PYR-GCK WSRVVAFLVLPALALVLAAGAG-------YLKWLDDSYRDGSMSVDGNGR
Mvan_4597|M.vanbaalenii_PYR-1 WARLTAFVLLPALALVLALGAG-------YLKWQDTTFRSGAIEASPSGR
MMAR_2889|M.marinum_M WWPAIGYGLLPALALLLAGGTG-------FAKWQDCAVRDAAQAR-----
MUL_2863|M.ulcerans_Agy99 WWPVIAYGLLPALALLLAGGTG-------FAKWQDCAVRDAAQAR-----
Rv1973|M.tuberculosis_H37Rv WSRVIAYGLLPGLALALTCGAG-------LLKWQDGAVRDAAVAR-----
MAV_1970|M.avium_104 WSRVVAFGVLPAIALLLAAAAG-------FFKWQDNSVRNTDIAR-----
TH_4601|M.thermoresistible__bu WLRIVTHAVLPALIVVSALGAG-------YLKWMDGTADAVDRAR-----
MSMEG_0353|M.smegmatis_MC2_155 SVRVLAYVVIPLLIVGLAACAG-------YLQWRSSSMRAAQAAN-----
Mb1397c|M.bovis_AF2122/97 WRMQVTLKPVPVILILLMLISGGATGWLYLEQYRPDQQTDSGAAR-----
MAB_4146c|M.abscessus_ATCC_199 WLARIFVAVTVLVVVGLSAAAG-------GMYWHRVDTVASRAAG-----
MLBr_02615|M.leprae_Br4923 PGLRLAVVSVCTAALCAAVLIG-------YMHWTSPDRDFSLDSR-----
: * :
Mflv_2108|M.gilvum_PYR-GCK PSLAETSVQAARDSTIALLSYAPDTVEQQLGAARELLTGEFRDSYTSLTN
Mvan_4597|M.vanbaalenii_PYR-1 LSLAEKTVQIARDSTIALLSYKPDTVEQQLGAARDLLTGEFRDSYTSLTN
MMAR_2889|M.marinum_M ----AESVQAATAGTIALLSYRPDTVRSDLDAARAKLTGAFLSDYTSLTR
MUL_2863|M.ulcerans_Agy99 ----AESVQAATAGTIALLSYRPDTVRSDLEAARAKLTGAFLSDYTSLTR
Rv1973|M.tuberculosis_H37Rv ----AESVRAATDGTTALLSYRPDTVQHDLESARSRLTGTFLDAYTQLTH
MAV_1970|M.avium_104 ----IESVQTAKDSTIAMLSYKPDTVEQQLRSARDLLTGEFRDSYTSLIT
TH_4601|M.thermoresistible__bu ----VESVQAATDITIAMLSYQPDTVEEDLGAARDRMTGEFRDSYTSLTN
MSMEG_0353|M.smegmatis_MC2_155 ----VSAVPAATDSTIKMLSYKPDTVQKDLELAAEGLTGPFRDDYNSLIH
Mb1397c|M.bovis_AF2122/97 -----AAGAAASDGTIALLSYSPDTLDQDFATARSHLAGDFLSYYDQFTQ
MAB_4146c|M.abscessus_ATCC_199 ----ETLIKQAGKQIGSIFGYDYQTVERSLDEQYAGLTPEYRREFEDKAN
MLBr_02615|M.leprae_Br4923 -----EVVQIATGMAEAMASFTPSAPTSSIDRAAAMIMPDQAGVFKEQYR
* : .: .: .: : : .
Mflv_2108|M.gilvum_PYR-GCK DVVIPGAKEKQIAAIATVPAAASVSVTADEAVVLLFVNQTVTVGPDA-PT
Mvan_4597|M.vanbaalenii_PYR-1 DVVIPGAKEKQISAVASVPAAASVSATPTEAVVLLFVNQTVSVGADV-PT
MMAR_2889|M.marinum_M DVVIPGAKQKDISAVATVPAAASVSATGEHAIVLLFVNQTIIVSQDA-PT
MUL_2863|M.ulcerans_Agy99 DVVIPGAKQKDISAVATVPAAASVSATGEHAIVLLFVNQTIIVSQDP-PT
Rv1973|M.tuberculosis_H37Rv DVVIPGAQQKQISAVATVAAAASVSTSADRAVVLLFVNQTITVGKDA-PT
MAV_1970|M.avium_104 DVVIPGAKQQQISAEASIPAAASVSADPREAVVLVFVNQTTIIGKSA-PT
TH_4601|M.thermoresistible__bu DVVIPGAREKRISTVATVPAAASVQASTDHAVVVVFVNQATTVGDDV-PT
MSMEG_0353|M.smegmatis_MC2_155 DVVIPGAQEKQISAVATVPAAAVVSATGNRAVVMVFVNQTTIVGADP-PT
Mb1397c|M.bovis_AF2122/97 QIVAPAAKQKSLKTTAKVVRAAVSELHPDSAVVLVFVDQSTTSKDSPNPS
MAB_4146c|M.abscessus_ATCC_199 REIIPQAKQRKIVSQTSIVGTGIIAAHRDSAQVVVYMNRTITDQSRT-PV
MLBr_02615|M.leprae_Br4923 KSSADLAR-RNVTAQASVLAAGVEAIGSSAASVAVILRVTQNTPGQP-PS
*: : : : :.: :. * * : : : *
Mflv_2108|M.gilvum_PYR-GCK DTASSVRVTLEKDGDRWLISKFDPV---
Mvan_4597|M.vanbaalenii_PYR-1 DTASSVRVTLEKVGDRWLISKFDPV---
MMAR_2889|M.marinum_M STASSVRVTLDKVDGRWLISRFDPV---
MUL_2863|M.ulcerans_Agy99 STASSVRVTLDKVDGRWLISRFDPV---
Rv1973|M.tuberculosis_H37Rv TAASSVRVTLDNINGRWLISQFEPI---
MAV_1970|M.avium_104 DTASTVRVTLNKAGDRWLISKFEPV---
TH_4601|M.thermoresistible__bu DTASTVRVTLEKVDDQWLMSGFEPI---
MSMEG_0353|M.smegmatis_MC2_155 STASTVRVTMDKVGERWLVSDFTPI---
Mb1397c|M.bovis_AF2122/97 MAASSVMVTLAKVDGNWLITKFTPV---
MAB_4146c|M.abscessus_ATCC_199 YDSSSIQVDYTRAGDKWLISYITPL---
MLBr_02615|M.leprae_Br4923 QAAPAVRVTLIKRGSDWLVTDVLSINAR
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