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LERPVVGALHSSLVTALGTGIVSGKYPAGCVLTLEAVSAEHGVSRSVAREAVRVLESMGMVESRRRVGIT VLPADRWNLFDPVVIRWRLEVGDRTAQLVSLSELRMGFEPAAAALAARRASPHQCRVMATAVSDMVMHGR TGDLDAYLLADKLFHQTMLEASGNEMFRALNGVVAEVLAGRTHHGMMPEKPNMAAIALHDEVARAIRMGE QEQAQRAMWAIIDESAMAIVEDGGAK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0501 | - | - | 100% (237) | GntR domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0958 | - | 8e-07 | 24.77% (214) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 8e-07 | 24.42% (217) | GntR domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0505 | - | 2e-08 | 27.75% (173) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0494 | - | 2e-08 | 27.75% (173) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 4e-09 | 27.11% (225) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0820 | - | 4e-10 | 24.03% (233) | GntR family transcriptional regulator |
| M. avium 104 | MAV_2542 | - | 3e-09 | 33.75% (160) | regulatory protein GntR, HTH |
| M. smegmatis MC2 155 | MSMEG_0454 | - | 1e-108 | 83.76% (234) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4024 | - | 2e-08 | 27.85% (219) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_4564 | - | 4e-10 | 24.03% (233) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5910 | - | 1e-114 | 88.41% (233) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0505|M.bovis_AF2122/97 -----MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPE
Rv0494|M.tuberculosis_H37Rv -----MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPE
MMAR_0820|M.marinum_M ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
MUL_4564|M.ulcerans_Agy99 ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
Mflv_0501|M.gilvum_PYR-GCK --------------MLERPVVGALHSSLVTALGTGIVSGKYPAGCVLTLE
Mvan_5910|M.vanbaalenii_PYR-1 --------------MLDRPNPGALHGSLLTALGTGIVSGQYPPGHVLTLE
MSMEG_0454|M.smegmatis_MC2_155 --------------MLDRPIAGELHGSLVAALGTGIVSGRYQPGHVLNLE
MAB_4644c|M.abscessus_ATCC_199 --------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKLPGE
TH_4024|M.thermoresistible__bu --------------MVRRVRAPRVAEVVASAIRDDILSGRLTEGDVLPTQ
MAV_2542|M.avium_104 MPKREPLAPMATSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFLPYE
: : * .* * * :
Mb0505|M.bovis_AF2122/97 RDLAERLGVNRTSLRQGLARLQQMGLIEVRHG--SGSVVRDPE--GLTHP
Rv0494|M.tuberculosis_H37Rv RDLAERLGVNRTSLRQGLARLQQMGLIEVRHG--SGSVVRDPE--GLTHP
MMAR_0820|M.marinum_M RELAEQLGVNRTSLRQGLARLQQMGLIETRQG--SGNVVRDPQ--SLTHP
MUL_4564|M.ulcerans_Agy99 RELAEQLGVNRTSLRQGLARLQQMGLIETRQG--SGNVVRDPQ--SLTHP
Mflv_0501|M.gilvum_PYR-GCK A-VSAEHGVSRSVAREAVRVLESMGMVESRRR--VGITVLPADRWNLFDP
Mvan_5910|M.vanbaalenii_PYR-1 A-VSTEHGVSRSVAREAVRVLESMGMLESRRR--VGITVQPAESWNVFDP
MSMEG_0454|M.smegmatis_MC2_155 G-ISAEHGVSRSVAREAVRVLESMGMVESRRR--VGITVQDPEKWNVFDP
MAB_4644c|M.abscessus_ATCC_199 VALCEEFGVSRATVREAIRDLKTKGLVSTRQG--AGVFVTSDRPLGQWDR
TH_4024|M.thermoresistible__bu EHLFTEFGVSPPALREAIRILETEGLVSVRRGNVGGAVVHLPSARRTAQM
MAV_2542|M.avium_104 AELMDHFQVSRPSLREAVRVLESDRLVEVRRGSRTGARVRVPGPEIVARP
: . *. . *:.: *: ::. *: * *
Mb0505|M.bovis_AF2122/97 AVVEALVRKLG-PDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAAL
Rv0494|M.tuberculosis_H37Rv AVVEALVRKLG-PDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAAL
MMAR_0820|M.marinum_M AVVEALVRKLG-PDFLVEVLEIRAALGPLIGRLAAERNSSEDAEALRAAL
MUL_4564|M.ulcerans_Agy99 AVVEALVRKLG-PDFLVEVLEIRAALGPLIGRLAAERNSSEDAEALRAAL
Mflv_0501|M.gilvum_PYR-GCK VVIRWRLEVGDRTAQLVSLSELRMGFEPAAAALAARRASPHQCRVMATAV
Mvan_5910|M.vanbaalenii_PYR-1 VVIRWRLEVGDRTAQLVSLSELRLGFEPAAAALAARRASPHQCRIMATAV
MSMEG_0454|M.smegmatis_MC2_155 VLIRWRLQAGDRTAQLVSLSELRLGFEPAAAALAARRASPHQCRVLATAV
MAB_4644c|M.abscessus_ATCC_199 VLA---------AAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIRRAL
TH_4024|M.thermoresistible__bu IAMVLQSR----SATPADVSEALLHLEPICAGMCAARPDRMSEVVPYLQD
MAV_2542|M.avium_104 AGFLLEMAG----TTLADVMTARMGIEPYAARLLAEDGTAAAHRELRELI
: : . : *
Mb0505|M.bovis_AF2122/97 EVVQQADTAA---ARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGRE
Rv0494|M.tuberculosis_H37Rv EVVQQADTAA---ARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGRE
MMAR_0820|M.marinum_M AEVADADTAP---ARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGGRE
MUL_4564|M.ulcerans_Agy99 AEVADADTAP---ARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGGRE
Mflv_0501|M.gilvum_PYR-GCK SDMVMHGRTGDLDAYLLADKLFHQTMLEASGNEMFRALNGVVAEVLAGRT
Mvan_5910|M.vanbaalenii_PYR-1 SDMVVHGRTGDLDAYLLADKLFHQTLLEASGNEMFRALNGVVAEVLTGRT
MSMEG_0454|M.smegmatis_MC2_155 SDMVMHGRNGDLAAYLAADKLFHQTMLEASGNEMFRALNGAVAEVLAGRT
MAB_4644c|M.abscessus_ATCC_199 VARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAM
TH_4024|M.thermoresistible__bu EIDLQSTSFADTARFVSNARRFHEMLVARCGNEPMILLIGALELIWSAHE
MAV_2542|M.avium_104 EEIPAAWETG---KLGAASTALHRRLVELSGNATLTVIVGMLHEIFERHM
.. :: * : : .
Mb0505|M.bovis_AF2122/97 HALTGAYDDA---------DPVLTDLRAINGAVLAGDPAAAAATVEAYLN
Rv0494|M.tuberculosis_H37Rv HALTGAYDDA---------DPVLTDLRAINGAVLAGDPAAAAATVEAYLN
MMAR_0820|M.marinum_M HELTGAYEDA---------DPVIADLTAINDAVLAGDPETAAAAVEGYLN
MUL_4564|M.ulcerans_Agy99 HDLTGAYEDA---------DPVIADLTAINDAVLAGDPETAAAAVEGYLN
Mflv_0501|M.gilvum_PYR-GCK HHGMMPEKPN---------MAAIALHDEVARAIRMGEQEQAQRAMWAIID
Mvan_5910|M.vanbaalenii_PYR-1 HHGLMPEKPN---------IAAIALHDEVARAIRMGEEQQAERAMRAIID
MSMEG_0454|M.smegmatis_MC2_155 HHGLMPEKPN---------IDAIALHDEVARAIRMGEADQAERAMRAIID
MAB_4644c|M.abscessus_ATCC_199 LALLAGSAER---------PHDQEHHQWLFDAIVDGSTRRAVELATDQLQ
TH_4024|M.thermoresistible__bu AGVWSDDSPGGGRPEAATMRAALRDHRRILDAVIDGDSARAVRLAQKHLA
MAV_2542|M.avium_104 TAAFLSVQNVVP---KAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHME
: : . * :
Mb0505|M.bovis_AF2122/97 ASALRMVKSYRDRA-----------
Rv0494|M.tuberculosis_H37Rv ASALRMVKSYRDRA-----------
MMAR_0820|M.marinum_M ASALRMIMCYRAAYAGEDPER----
MUL_4564|M.ulcerans_Agy99 ASALRMIMCYRAAYAGEDPER----
Mflv_0501|M.gilvum_PYR-GCK ESAMAIVEDGGAK------------
Mvan_5910|M.vanbaalenii_PYR-1 ESASAIVEDSPPSD-----------
MSMEG_0454|M.smegmatis_MC2_155 ESVSAIVEVGPPGAGTAAQA-----
MAB_4644c|M.abscessus_ATCC_199 HVRMR--------------------
TH_4024|M.thermoresistible__bu AARRHTLACGADTTIEAKLVSRPDH
MAV_2542|M.avium_104 NASAELLKGHEKTKVRDIMH-----