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M. thermoresistible (build 8) TH_4024 (-)

annotation: transcriptional regulator, GntR family
coordinates: 2179034 - 2179807
length: 258

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4024--100% (258)transcriptional regulator, GntR family
M. thermoresistible (build 8)TH_2873-1e-2430.83% (240) PUTATIVE regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_4408-4e-2430.24% (248) PUTATIVE regulatory protein GntR, HTH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3086c-6e-1427.98% (243) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_4358-1e-9470.83% (240) regulatory protein GntR, HTH
M. tuberculosis H37RvRv3060c-6e-1427.98% (243) GntR family transcriptional regulator
M. leprae Br4923MLBr_01188-3e-1647.06% (85) hypothetical protein MLBr_01188
M. abscessus ATCC 19977MAB_4644c-2e-1228.02% (232) GntR family transcriptional regulator
M. marinum MMMAR_3975-1e-5544.36% (257) FadR family transcriptional regulator
M. avium 104MAV_1634-2e-5545.16% (248) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_5201-1e-2531.91% (235) regulatory protein GntR, HTH
M. ulcerans Agy99MUL_3832-3e-5644.75% (257) FadR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1986-1e-10472.83% (254) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4358|M.gilvum_PYR-GCK          ------------------------------MASRLRDDILTGRLKEGDVL
Mvan_1986|M.vanbaalenii_PYR-1       ----------------MPAQRIRQPRVAELVASRLRDDILTGRLKEGDVL
TH_4024|M.thermoresistible__bu      -----------------MVRRVRAPRVAEVVASAIRDDILSGRLTEGDVL
MMAR_3975|M.marinum_M               --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99           --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MAV_1634|M.avium_104                --------MTALGIGPDARRRLSAPRIAEIVADELRRQIISGELADGDLL
MLBr_01188|M.leprae_Br4923          -------------------------------------------------M
Mb3086c|M.bovis_AF2122/97           --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Rv3060c|M.tuberculosis_H37Rv        --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
MSMEG_5201|M.smegmatis_MC2_155      MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MAB_4644c|M.abscessus_ATCC_199      -----------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKL
                                                                                     :

Mflv_4358|M.gilvum_PYR-GCK          PSQESLFAEFGVSPPAVREAIHILEADGLISVRRGNVGGAVVHLPSAERT
Mvan_1986|M.vanbaalenii_PYR-1       PSQEALFAEFGVSPPAVREAVHILESDGLISVRRGNIGGAVVHLPSAERT
TH_4024|M.thermoresistible__bu      PTQEHLFTEFGVSPPALREAIRILETEGLVSVRRGNVGGAVVHLPSARRT
MMAR_3975|M.marinum_M               PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99           PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MAV_1634|M.avium_104                PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MLBr_01188|M.leprae_Br4923          PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSA
Mb3086c|M.bovis_AF2122/97           GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv        GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
MSMEG_5201|M.smegmatis_MC2_155      PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MAB_4644c|M.abscessus_ATCC_199      PGEVALCEEFGVSRATVREAIRDLKTKGLVSTRQG----AGVFVTSDRPL
                                      :  *   : **   .***:: :. . :   *:*      :  .     

Mflv_4358|M.gilvum_PYR-GCK          AQMISMVLQTRAATPGDVSEALLHLEPICAGMCASREDR-----------
Mvan_1986|M.vanbaalenii_PYR-1       AQMISMVLQTRSATPADVSEALLHLEPICAGMCASRGDR-----------
TH_4024|M.thermoresistible__bu      AQMIAMVLQSRSATPADVSEALLHLEPICAGMCAARPDR-----------
MMAR_3975|M.marinum_M               AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDR-----------
MUL_3832|M.ulcerans_Agy99           AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDR-----------
MAV_1634|M.avium_104                AYMLGLLLQSESVAVADLGMALQELEPACAALAARRPDR-----------
MLBr_01188|M.leprae_Br4923          AYMLGLLLQSKSIALADLGAALQELEPACAALAAQ---------------
Mb3086c|M.bovis_AF2122/97           TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR
Rv3060c|M.tuberculosis_H37Rv        TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR
MSMEG_5201|M.smegmatis_MC2_155      ARPVGLLLELSGADIADLLVARSAIEPMAARLLAENGTE-----------
MAB_4644c|M.abscessus_ATCC_199      GQWDRVLA---AAEIDAVVEIRRLLEVQAAGLAAERRNR-----------
                                         :     .     :      :*  .* : *                

Mflv_4358|M.gilvum_PYR-GCK          -ATEVVPHLQAAIDAQVEQFDSPSQ------YVPNARRFHEAIVSHCGNE
Mvan_1986|M.vanbaalenii_PYR-1       -MTEVVPHLQAAIDVQVEQFDRTSR------YVSNARRFHEAIVSRCGNE
TH_4024|M.thermoresistible__bu      -MSEVVPYLQDEIDLQSTSFADTAR------FVSNARRFHEMLVARCGNE
MMAR_3975|M.marinum_M               -ADTLVPELKRVNEAMSEHLDDGAM------FTEIGRQFHDLIVRGCGNH
MUL_3832|M.ulcerans_Agy99           -ADTLVPELKRVNEAMSEHLDDGAM------FTEIGRQFHDLIVRGCGNH
MAV_1634|M.avium_104                -ADTLVPELTKINESMATHLDDGRL------FTEIGRQFHDLVVRGCGNH
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ
Rv3060c|M.tuberculosis_H37Rv        AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ
MSMEG_5201|M.smegmatis_MC2_155      ---EQFAELDRMLEEHIPSDWQSDR------LAETTGDFHRRVVELSGNA
MAB_4644c|M.abscessus_ATCC_199      ---SDVAAIRRALVARAKAESAGDD----IEYVDADLEFHRAVVAAVHNP
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          PMILLIGSLQVIWSAHESSVWSDEYHPSDPMEPKTMR-AALRD------H
Mvan_1986|M.vanbaalenii_PYR-1       PMILLIGSLELIWSAHESSVWSDECHPEDPMRPKTMR-AALRD------H
TH_4024|M.thermoresistible__bu      PMILLIGALELIWSAHEAGVWSDDSPGGGRPEAATMR-AALRD------H
MMAR_3975|M.marinum_M               TIIAVVGSLETLWTSHEQ-QWADESAARGTYPSLTKRRAVLNT------H
MUL_3832|M.ulcerans_Agy99           TIIAVVGSLETLWTSHEQ-QWADESAARGTYPSLAKRRAVLNA------H
MAV_1634|M.avium_104                TIIAVVGSLETLWTSHER-QWADESSSRGTYPSLAQRRAVLNT------H
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ
Rv3060c|M.tuberculosis_H37Rv        SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ
MSMEG_5201|M.smegmatis_MC2_155      TLGIIAGMLHEITVRHHQFLFREHRPVSKSDYDKLMR-----------SY
MAB_4644c|M.abscessus_ATCC_199      LLDELFDSFSVRMREAMLALLAGSAERPHDQEH----------------H
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          QRLLDAIAEGNSARAVKLAGDHLAAARRNTLAAASQKTIEAKLISN----
Mvan_1986|M.vanbaalenii_PYR-1       HRIVEAIIDGNSSRAVRLAEDHLAAARHNTLAAGSDRTIEAKLIANHDR-
TH_4024|M.thermoresistible__bu      RRILDAVIDGDSARAVRLAQKHLAAARRHTLACGADTTIEAKLVSRPDH-
MMAR_3975|M.marinum_M               IKLTETIAEGDVDRARRIAGRHLADTQTYVLSGRAEQRIYALSPQALSRP
MUL_3832|M.ulcerans_Agy99           IKLTETIAEGDVDRARRIAGRHLADTQTYVLSGRAEQRIYALSPQALSRP
MAV_1634|M.avium_104                VKLTETIAEGNVDRARRIAGRHLADTQTYVLSGQPDQRIHAFSPQALARP
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV
Rv3060c|M.tuberculosis_H37Rv        RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV
MSMEG_5201|M.smegmatis_MC2_155      RKLMQIMRSGDGDAAEAHWRTHLDTARALMLQGLESVKVRDVMG------
MAB_4644c|M.abscessus_ATCC_199      QWLFDAIVDGSTRRAVELATDQLQHVRMR---------------------
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MMAR_3975|M.marinum_M               RDMRRP--------------------------------------------
MUL_3832|M.ulcerans_Agy99           RDMRRP--------------------------------------------
MAV_1634|M.avium_104                RDLRRS--------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ
Rv3060c|M.tuberculosis_H37Rv        GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL
Rv3060c|M.tuberculosis_H37Rv        PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR
Rv3060c|M.tuberculosis_H37Rv        DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA
Rv3060c|M.tuberculosis_H37Rv        RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_4358|M.gilvum_PYR-GCK          ----
Mvan_1986|M.vanbaalenii_PYR-1       ----
TH_4024|M.thermoresistible__bu      ----
MMAR_3975|M.marinum_M               ----
MUL_3832|M.ulcerans_Agy99           ----
MAV_1634|M.avium_104                ----
MLBr_01188|M.leprae_Br4923          ----
Mb3086c|M.bovis_AF2122/97           SWWL
Rv3060c|M.tuberculosis_H37Rv        SWWL
MSMEG_5201|M.smegmatis_MC2_155      ----
MAB_4644c|M.abscessus_ATCC_199      ----