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MLDRPIAGELHGSLVAALGTGIVSGRYQPGHVLNLEGISAEHGVSRSVAREAVRVLESMGMVESRRRVGI TVQDPEKWNVFDPVLIRWRLQAGDRTAQLVSLSELRLGFEPAAAALAARRASPHQCRVLATAVSDMVMHG RNGDLAAYLAADKLFHQTMLEASGNEMFRALNGAVAEVLAGRTHHGLMPEKPNIDAIALHDEVARAIRMG EADQAERAMRAIIDESVSAIVEVGPPGAGTAAQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0454 | - | - | 100% (244) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0124 | - | 5e-14 | 30.22% (225) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_5201 | - | 1e-12 | 30.45% (220) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0505 | - | 5e-10 | 28.49% (172) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0501 | - | 1e-108 | 83.76% (234) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0494 | - | 5e-10 | 28.49% (172) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1705c | - | 3e-10 | 28.44% (211) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0820 | - | 3e-10 | 24.03% (233) | GntR family transcriptional regulator |
| M. avium 104 | MAV_2542 | - | 3e-09 | 33.12% (160) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_1959 | - | 3e-09 | 27.19% (217) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (GNTR-FAMILY) |
| M. ulcerans Agy99 | MUL_4564 | - | 3e-10 | 24.03% (233) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5910 | - | 1e-112 | 85.59% (236) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0505|M.bovis_AF2122/97 -----MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPE
Rv0494|M.tuberculosis_H37Rv -----MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPE
MMAR_0820|M.marinum_M ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
MUL_4564|M.ulcerans_Agy99 ---------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPE
Mflv_0501|M.gilvum_PYR-GCK --------------MLERPVVGALHSSLVTALGTGIVSGKYPAGCVLTLE
Mvan_5910|M.vanbaalenii_PYR-1 --------------MLDRPNPGALHGSLLTALGTGIVSGQYPPGHVLTLE
MSMEG_0454|M.smegmatis_MC2_155 --------------MLDRPIAGELHGSLVAALGTGIVSGRYQPGHVLNLE
TH_1959|M.thermoresistible__bu -------------MALQPVNRRSVPEDVFDQIVGEVLSGQMQPGDALPSE
MAB_1705c|M.abscessus_ATCC_199 ---------MPVPPSEGIAARSLLRDNAYKALRTAIVDGTLAPGERLRDD
MAV_2542|M.avium_104 MPKREPLAPMATSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFLPYE
: ::.* * * :
Mb0505|M.bovis_AF2122/97 RDLAERLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPE--GLTHPAV
Rv0494|M.tuberculosis_H37Rv RDLAERLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPE--GLTHPAV
MMAR_0820|M.marinum_M RELAEQLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQ--SLTHPAV
MUL_4564|M.ulcerans_Agy99 RELAEQLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQ--SLTHPAV
Mflv_0501|M.gilvum_PYR-GCK A-VSAEHGVSRSVAREAVRVLESMGMVESRRRVGITVLPADRWNLFDPVV
Mvan_5910|M.vanbaalenii_PYR-1 A-VSTEHGVSRSVAREAVRVLESMGMLESRRRVGITVQPAESWNVFDPVV
MSMEG_0454|M.smegmatis_MC2_155 G-ISAEHGVSRSVAREAVRVLESMGMVESRRRVGITVQDPEKWNVFDPVL
TH_1959|M.thermoresistible__bu RRLAEVLGVSRPAVREALKRLSAAGLVEVRQGEITTVRDYRRHAGLDLLP
MAB_1705c|M.abscessus_ATCC_199 E-LSRWLGVSRTPIREALARLEQAGLVQTQPGRHTIVSPID---------
MAV_2542|M.avium_104 AELMDHFQVSRPSLREAVRVLESDRLVEVRRGSRTGARVRVPGPEIVARP
: *.*. *:.: *. ::: : .
Mb0505|M.bovis_AF2122/97 VEALVRKLG-PDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAALEV
Rv0494|M.tuberculosis_H37Rv VEALVRKLG-PDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAALEV
MMAR_0820|M.marinum_M VEALVRKLG-PDFLVEVLEIRAALGPLIGRLAAERNSSEDAEALRAALAE
MUL_4564|M.ulcerans_Agy99 VEALVRKLG-PDFLVEVLEIRAALGPLIGRLAAERNSSEDAEALRAALAE
Mflv_0501|M.gilvum_PYR-GCK IRWRLEVGDRTAQLVSLSELRMGFEPAAAALAARRASPHQCRVMATAVSD
Mvan_5910|M.vanbaalenii_PYR-1 IRWRLEVGDRTAQLVSLSELRLGFEPAAAALAARRASPHQCRIMATAVSD
MSMEG_0454|M.smegmatis_MC2_155 IRWRLQAGDRTAQLVSLSELRLGFEPAAAALAARRASPHQCRVLATAVSD
TH_1959|M.thermoresistible__bu RLLFRAGELDVTVVRSILETRLHNGPKVAELAARRRPPGLGALLDEAVQT
MAB_1705c|M.abscessus_ATCC_199 ----------VREARAAQSVAAAMHELAVREAITNISPGDLAAMRHANTR
MAV_2542|M.avium_104 AGFLLEMAG--TTLADVMTARMGIEPYAARLLAEDGTAAAHRELRELIEE
.. :
Mb0505|M.bovis_AF2122/97 VQQADTAA---ARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGREHA
Rv0494|M.tuberculosis_H37Rv VQQADTAA---ARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGREHA
MMAR_0820|M.marinum_M VADADTAP---ARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGGREHE
MUL_4564|M.ulcerans_Agy99 VADADTAP---ARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGGREHD
Mflv_0501|M.gilvum_PYR-GCK MVMHGRTGDLDAYLLADKLFHQTMLEASGNEMFRALNGVVAEVLAGRTHH
Mvan_5910|M.vanbaalenii_PYR-1 MVVHGRTGDLDAYLLADKLFHQTLLEASGNEMFRALNGVVAEVLTGRTHH
MSMEG_0454|M.smegmatis_MC2_155 MVMHGRNGDLAAYLAADKLFHQTMLEASGNEMFRALNGAVAEVLAGRTHH
TH_1959|M.thermoresistible__bu LAAETDPVE---RQRHALRFWDHVVDGADSIAFRLMYNTLRATYEPALPA
MAB_1705c|M.abscessus_ATCC_199 FAAALDAHDPDAALAADDEFHAVAVEASANPYIAAVLEQVTPVLR-RLER
MAV_2542|M.avium_104 IPAAWETG---KLGAASTALHRRLVELSGNATLTVIVGMLHEIFERHMTA
. :. : . : : :
Mb0505|M.bovis_AF2122/97 LTGAYDDAD------PVLTDLRAINGAVLAGDPAAAAATVEAYLNASALR
Rv0494|M.tuberculosis_H37Rv LTGAYDDAD------PVLTDLRAINGAVLAGDPAAAAATVEAYLNASALR
MMAR_0820|M.marinum_M LTGAYEDAD------PVIADLTAINDAVLAGDPETAAAAVEGYLNASALR
MUL_4564|M.ulcerans_Agy99 LTGAYEDAD------PVIADLTAINDAVLAGDPETAAAAVEGYLNASALR
Mflv_0501|M.gilvum_PYR-GCK GMMPEKPNM------AAIALHDEVARAIRMGEQEQAQRAMWAIIDESAMA
Mvan_5910|M.vanbaalenii_PYR-1 GLMPEKPNI------AAIALHDEVARAIRMGEEQQAERAMRAIIDESASA
MSMEG_0454|M.smegmatis_MC2_155 GLMPEKPNI------DAIALHDEVARAIRMGEADQAERAMRAIIDESVSA
TH_1959|M.thermoresistible__bu LATMMAAEV------GRPQAYRALAAAIEAGDPTAAEQSARDLLEPATAA
MAB_1705c|M.abscessus_ATCC_199 IRFASRDGR------HSVALHEQIIARCEAGDSEGAGRAARDNWHTLIAA
MAV_2542|M.avium_104 AFLSVQNVVPKAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHMENASAE
: : * .
Mb0505|M.bovis_AF2122/97 MVKSYRDRA-------
Rv0494|M.tuberculosis_H37Rv MVKSYRDRA-------
MMAR_0820|M.marinum_M MIMCYRAAYAGEDPER
MUL_4564|M.ulcerans_Agy99 MIMCYRAAYAGEDPER
Mflv_0501|M.gilvum_PYR-GCK IVEDGGAK--------
Mvan_5910|M.vanbaalenii_PYR-1 IVEDSPPSD-------
MSMEG_0454|M.smegmatis_MC2_155 IVEVGPPGAGTAAQA-
TH_1959|M.thermoresistible__bu LLSALDELEAQK----
MAB_1705c|M.abscessus_ATCC_199 PEGAAHEERGAG----
MAV_2542|M.avium_104 LLKGHEKTKVRDIMH-