For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRSERQPMIVDPRATPDSVPPVAGGALLAVAVVLAALNLRPAVTSIATLLHDIRGDLAVSATWAGLVTTL PALCFAGAGLAAPWVASRIGLSRAISVALLALTAGLALRGVGGEYVVIGATLIACAGIALANVLIPVVIK TSFPARIGMMTGIYTAALQGGGALGSAVTPGLADPLGGWRTALMVWAAVSLLALTLWIPATARHRSAWAV HTRPSAARRSLLRSPLAWTVTVFFGSQAFLAYIMMGWLPQVFIDNGIDKVQAGLLVAVASLVGVPLSLVI TPLAARSASQSGWIVGVGSFGFLGTVGLMVAPTAQPLLWSVLLGTGLSGFSLALALLGLRARTPEDTAAL SGMAQGFGYLLAGTGPFLFGLLHDVTHGWTAPWVLFLAVFCVQTVTGALAGRNRYV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0017 | - | - | 100% (406) | major facilitator transporter |
| M. gilvum PYR-GCK | Mflv_3439 | - | 4e-11 | 23.83% (407) | major facilitator transporter |
| M. gilvum PYR-GCK | Mflv_4231 | - | 5e-08 | 25.66% (265) | major facilitator transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0298 | - | 7e-06 | 28.37% (349) | transmembrane protein |
| M. tuberculosis H37Rv | Rv0290 | - | 7e-06 | 28.37% (349) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2273 | - | 9e-57 | 36.77% (378) | MFS family transporter |
| M. marinum M | MMAR_0750 | - | 3e-57 | 33.33% (408) | MFS transporter |
| M. avium 104 | MAV_3846 | - | 1e-07 | 23.96% (384) | sugar transporter family protein |
| M. smegmatis MC2 155 | MSMEG_2795 | - | 1e-144 | 66.93% (384) | transmembrane transport protein |
| M. thermoresistible (build 8) | TH_2039 | - | 1e-06 | 25.27% (182) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1382 | - | 1e-56 | 33.42% (386) | MFS transporter |
| M. vanbaalenii PYR-1 | Mvan_0951 | - | 1e-180 | 76.17% (407) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0017|M.gilvum_PYR-GCK ------------------MRSERQPMIVDPRATPDS-VPPVAGG-ALLAV
Mvan_0951|M.vanbaalenii_PYR-1 ------------------MRTERQEITTDPTLDPASRVPTVAGG-ALLAV
MSMEG_2795|M.smegmatis_MC2_155 -------------MPRNSLDSYEHDLELEIDGAAEFRAPAMAAGGVLLAV
MMAR_0750|M.marinum_M -----------------------MTAVAAPAIHDPTASRSLFASRVTVLL
MUL_1382|M.ulcerans_Agy99 ------------------------------MIHDPTASRSLFASRVTVLL
MAB_2273|M.abscessus_ATCC_1997 -----------------------MTATLRDETHMISAA-ALRRGRLMVLA
MAV_3846|M.avium_104 MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMV
TH_2039|M.thermoresistible__bu --------------------------------MPVSS--ISPARRWSMLV
Mb0298|M.bovis_AF2122/97 -------------MSGTVMQIVRVAILADSRLTEMALPAELPLREILPAV
Rv0290|M.tuberculosis_H37Rv -------------MSGTVMQIVRVAILADSRLTEMALPAELPLREILPAV
Mflv_0017|M.gilvum_PYR-GCK AVVLAALNLR---------PAVTSIATLLHDIRGDLAVSATWAGLVT-TL
Mvan_0951|M.vanbaalenii_PYR-1 AVVLTALNLR---------PAVTSIATVLGDIRAELSVSATWAGLLM-TL
MSMEG_2795|M.smegmatis_MC2_155 AVVLTALNLR---------PAITSVGPLLGDMRSDLGASGVWAGVLT-TM
MMAR_0750|M.marinum_M AIALSAFTMR---------SAVTSMAPLLARVADTMGFGGTVIGVFG-ML
MUL_1382|M.ulcerans_Agy99 AIALSAFTMR---------SAVTSMAPLLARVADTMGFGGTVIGVFG-ML
MAB_2273|M.abscessus_ATCC_1997 AILLFALCLR---------SAVTSLSPLLTQISHEIGFGSAVIGVFG-ML
MAV_3846|M.avium_104 VSLLATASSF---------LFINGVAFLIPSLQGARGIRLDEAGLLA-SM
TH_2039|M.thermoresistible__bu IALAATLFSV---------VFINGVAFVIPTLHREHGLSLAQAGLLS-AL
Mb0298|M.bovis_AF2122/97 QRLVVPSAQNGDGGQADSGAAVQLSLAPVGGQPFSLDASLDTVGVVDGDL
Rv0290|M.tuberculosis_H37Rv QRLVVPSAQNGDGGQADSGAAVQLSLAPVGGQPFSLDASLDTVGVVDGDL
. : : *:. :
Mflv_0017|M.gilvum_PYR-GCK PALCFAGAGLAAPWVASRIGLSRAISVALLALTAGLALR-GVGGEYVVIG
Mvan_0951|M.vanbaalenii_PYR-1 PALCFAGAGFAAPWLAARVGLGRTISAAMVALTAGLALR-GAAGPHVIIG
MSMEG_2795|M.smegmatis_MC2_155 PGLCFAAAGLAAPWLARKLGLGWAISLAMGVLTVGLLVR-VLDGALVVLG
MMAR_0750|M.marinum_M PTAMFALAGFAAP-LSRRFGPERLALLSVLATAAGTAGRSMASDTSELMA
MUL_1382|M.ulcerans_Agy99 PTAMFALAGFAAP-LSRRFGPERLALLSVLATAAGTAGRSMASDTSELMA
MAB_2273|M.abscessus_ATCC_1997 PTAMFAIAGLVTPALTERFGLERTTLAAVVATVIGMAARTAMNSTGGLLV
MAV_3846|M.avium_104 PSWGMVVTLVAWGYVLDRVGERVVMTTGSALTALAAYAASSAHSMVLIAV
TH_2039|M.thermoresistible__bu PSFGMVATLIAWGYLVDRIGERIVLTVGSALTAASAFAAAAVDSLLLVGV
Mb0298|M.bovis_AF2122/97 LVLQPVPAGPAAPGIVEDIADAAMIFSTSRLKPWG--IAHIQRGALAAVI
Rv0290|M.tuberculosis_H37Rv LVLQPVPAGPAAPGIVEDIADAAMIFSTSRLKPWG--IAHIQRGALAAVI
. : . : .. . .
Mflv_0017|M.gilvum_PYR-GCK ATLIACAGIALANVLIPVVIKTSFP-ARIGMMTGIYTAALQGGG------
Mvan_0951|M.vanbaalenii_PYR-1 ATLVACAGIALVNVLIPVVIKGSFP-ARIGLMTGIYTAALQGGG------
MSMEG_2795|M.smegmatis_MC2_155 GTLVATGGIALINVLIPVVIKGSFP-ARIGLMTGIYTAALQGGG------
MMAR_0750|M.marinum_M FTTLALVGMGIANIVIPPLVKKYFN-DRVALMSAIYLACLQLGT------
MUL_1382|M.ulcerans_Agy99 FTTLALVGMGIANIVVPPLVKKYFN-DRVALMSAIYLACLQLGT------
MAB_2273|M.abscessus_ATCC_1997 LSCLALLGMGIGNVVIPPLVKRYFS-HRVALMSAAYLTVLQIGT------
MAV_3846|M.avium_104 YLFLGGMAAASCNTAGGRLVSAWFPPHQRGLAMGIRQTAQPLGI------
TH_2039|M.thermoresistible__bu FLLLGGMAAASSNTASARVVVGWFPPHQRGLVMGIRQTAQPLGV------
Mb0298|M.bovis_AF2122/97 AVALLATGLTVTYRVATGVLAGLLAVAGIAVASALAGLLITIRSPRSGIA
Rv0290|M.tuberculosis_H37Rv AVALLATGLTVTYRVATGVLAGLLAVAGIAVASALAGLLITIRSPRSGIA
: . :: : .: .
Mflv_0017|M.gilvum_PYR-GCK -------ALGSAVTPGLADPLGGWRTALMVWAAVSLLALTLWIPATARHR
Mvan_0951|M.vanbaalenii_PYR-1 -------ALGSAVTPGLEEPLGGWRAAVAVWAVVSLLALMVWIPATGRHR
MSMEG_2795|M.smegmatis_MC2_155 -------ALGSGVTSPLQDVLGGWREALGSWTVLALAALVVWLLAARSIH
MMAR_0750|M.marinum_M -------IMPAVAAVPLAESYG-WRASLAIWALIPAVAVLPWILVLVRRR
MUL_1382|M.ulcerans_Agy99 -------IMPAVAAVPLAESYG-WRASLAIWALIPAVAVLPWILVLVRRR
MAB_2273|M.abscessus_ATCC_1997 -------TVPALTAVPLADAYG-WRFSLVAWVLVPVAALLPWIGVVIARR
MAV_3846|M.avium_104 -------ALGAMVIPELAE-HGPQAGLRFTALACVFGAVASVIGIVDPPR
TH_2039|M.thermoresistible__bu -------ALGALVIPRLAQSHGISAALLFPAAVCAVAAVICLIGVLDPPR
Mb0298|M.bovis_AF2122/97 LSIAALVPIGAALALAVPGKFGPAQVLLGAAGVAAWSLIALMIPSAERER
Rv0290|M.tuberculosis_H37Rv LSIAALVPIGAALALAVPGKFGPAQVLLGAAGVAAWSLIALMIPSAERER
: : : * : : :
Mflv_0017|M.gilvum_PYR-GCK SAWAVHTRPS-----AARRSLLRSPLAWTVTVFFGSQAFLAYIMMGWLPQ
Mvan_0951|M.vanbaalenii_PYR-1 GAWAAHSLP------AGRRSLLRSPLAWTITVFFGSQAFMAYIVMGWLPQ
MSMEG_2795|M.smegmatis_MC2_155 GARTTPMTAS-----GKSRSLLRNPLAWTVTLFFGCQAFLAYIVMGWLPE
MMAR_0750|M.marinum_M -TNGTDHAAR---TGKKIGPIWRSPISWGLTFMFSMTSLITYAMFAWLPV
MUL_1382|M.ulcerans_Agy99 -TNGTDHAAR---TGKKIGPIWRSPISWGLTFMFSMTSLITYAMFAWLPV
MAB_2273|M.abscessus_ATCC_1997 GHDVEDHSAEPHADSAAVGQVWRSPLAWGMAGMFGMTSLVTYSMFTWIPA
MAV_3846|M.avium_104 KPRASASDQE------LASPYRGSLTLWRIHAVAGLMMMPQTVTVTFMLV
TH_2039|M.thermoresistible__bu PPRASADGRH------PQNPYRGSGLLWRIHAVSVLLVVPQGVIWTFTLV
Mb0298|M.bovis_AF2122/97 VVAFFTAAAVVG---ASVALAAGAQLLWQLPLLS----IGCGLIVAALLV
Rv0290|M.tuberculosis_H37Rv VVAFFTAAAVVG---ASVALAAGAQLLWQLPLLS----IGCGLIVAALLV
* : . .
Mflv_0017|M.gilvum_PYR-GCK VFIDNG-IDKVQAGLLVAVASLVGVPLSLVITPLAARSASQSGWIVGVGS
Mvan_0951|M.vanbaalenii_PYR-1 VLVDNG-VDQVQAGLLVGLMSLIGVPISLLIAPMAARRPSQSGWIVAVGM
MSMEG_2795|M.smegmatis_MC2_155 VFIDSG-VGKTQAGLLVGLVSLLAVPISLVVAPLAARQSGQTGWIVGLGV
MMAR_0750|M.marinum_M IVTSAG-GSEALGGAMVATFSGVGFLATLVTPRLCARAANPFPIVAASAL
MUL_1382|M.ulcerans_Agy99 IVTSAG-GSEALGGAMVATFSGVGFLATLVTPRLCARAANPFPIVAASAL
MAB_2273|M.abscessus_ATCC_1997 ILASAG-GSAKLGGVMVALFSAVGFVGTLAIPPLAARMRNPFPLVVACLV
MAV_3846|M.avium_104 WLIRNLHWSVAAAGALVTLSQLLGALGRVAVGRWSDRLGSRMRPVRYIAA
TH_2039|M.thermoresistible__bu WLMTERSWSAGSAGTMVMIAQVLGAGGRVAAGRWSDLVGSRLRPIRTIAL
Mb0298|M.bovis_AF2122/97 TIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPRRVRVSDAHQS
Rv0290|M.tuberculosis_H37Rv TIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPRRVRVSDAHQS
. :
Mflv_0017|M.gilvum_PYR-GCK FGFLGTVGLMVAPTAQPLLWSVLLGTGLSGFSLALALLGLRARTPEDTAA
Mvan_0951|M.vanbaalenii_PYR-1 FGFAGAIGLMVAPAAQPLLWSVLIGIGMSAFSMALAVLGLRARTAADTAQ
MSMEG_2795|M.smegmatis_MC2_155 VGFAGMVGLLVDPGAAPLLWSVLVGLGMSVFSLALTVIALRARTADDTAQ
MMAR_0750|M.marinum_M CFLVGFAGLLWAPLTAPIVWAIFLGLGPSTFPAAITLINLRSRTESGSAA
MUL_1382|M.ulcerans_Agy99 CFLVGFAGLLWAPLTAPIVWAIFLGLGPSTFPAAITLINLRSRTESGSAA
MAB_2273|M.abscessus_ATCC_1997 CFLIGFAGLLWLPMHGTAVWVVALGFGPSTFPLGLTLVNLRTRTPAGSAA
MAV_3846|M.avium_104 AAVLVLLLLAWADYLN-SRWQAGLMVAISVIAVLDNGLEATAITEFAGPY
TH_2039|M.thermoresistible__bu AAAAAMALLALTDALD-SPVSVAFMVIAAVVTVSDNSLAFTAIAEIAGPY
Mb0298|M.bovis_AF2122/97 GFIAAAVLLSVLGSVAIAVRPEALSVVGWYLVAATAAAATLRARVWDSAA
Rv0290|M.tuberculosis_H37Rv GFIAAAVLLSVLGSVAIAVRPEALSVVGWYLVAATAAAATLRARVWDSAA
* . . .
Mflv_0017|M.gilvum_PYR-GCK LSGMAQGFG----YLLAGTGPFLFGLLHDVTHGWTAPWVLFLAVFCVQTV
Mvan_0951|M.vanbaalenii_PYR-1 LSGMVQGFG----YLIAGAGPFLFGLLHDVSHGWTVPWMMFLAVYAVQIV
MSMEG_2795|M.smegmatis_MC2_155 LSGMAQGFG----YLLAGFGPFLFGLLHDVTGGWTAPWALVLAVYLVQMG
MMAR_0750|M.marinum_M LSGFTQGMG----YLLASPGPLIFGILYNATGRWELSFGFLLVPLIALLA
MUL_1382|M.ulcerans_Agy99 LSGFTQGMG----YLLASPGPLIFGILYNATGRWELSFGFLLVPLIALLA
MAB_2273|M.abscessus_ATCC_1997 LSGFTQGVG----YAVACLGPLLFGVLHDVSGGWYAPFGLLLVAITVLGV
MAV_3846|M.avium_104 WSGRALGIQNTTQRMMAAAGPPLFGALISAAK-YPPAWLLCALFPLAAMP
TH_2039|M.thermoresistible__bu WTGRALGTQNTSQLLTTAITPPLFGGLIGVAG-YPVAFALCAVLPLAAVP
Mb0298|M.bovis_AF2122/97 CKAWLLAQP----YLVAG----VLLVFYTTTGRYVAAFGAVLVLAVLMLA
Rv0290|M.tuberculosis_H37Rv CKAWLLAQP----YLVAG----VLLVFYTATGRYVAAFGAVLVLAVLMLA
.. . : :: : .: : .:
Mflv_0017|M.gilvum_PYR-GCK TGALAGRNRYV---------------------------------------
Mvan_0951|M.vanbaalenii_PYR-1 AGALAGRARYV---------------------------------------
MSMEG_2795|M.smegmatis_MC2_155 AGALAGRNRYV---------------------------------------
MMAR_0750|M.marinum_M GGYHACKPRYLEDTLTPSRKSGSDAVEDVVEGERLQECSTSCA-------
MUL_1382|M.ulcerans_Agy99 GGYHACKPRYLEDTLTPSRKSGSDAVEDVVEGERLQECSTSCA-------
MAB_2273|M.abscessus_ATCC_1997 GAFQACKPRTLEDTWN----RGSGAVVSS---------------------
MAV_3846|M.avium_104 LVPTRLLPPGLETRARRQSVRRLRWWRAVRSHALPDIVRRPGQPG-----
TH_2039|M.thermoresistible__bu LVPADPATPQIRPSSP-ESPRRVR--------------------------
Mb0298|M.bovis_AF2122/97 WVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVGLFAWVL
Rv0290|M.tuberculosis_H37Rv WVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVGLFAWVL
Mflv_0017|M.gilvum_PYR-GCK --
Mvan_0951|M.vanbaalenii_PYR-1 --
MSMEG_2795|M.smegmatis_MC2_155 --
MMAR_0750|M.marinum_M --
MUL_1382|M.ulcerans_Agy99 --
MAB_2273|M.abscessus_ATCC_1997 --
MAV_3846|M.avium_104 --
TH_2039|M.thermoresistible__bu --
Mb0298|M.bovis_AF2122/97 NR
Rv0290|M.tuberculosis_H37Rv NR