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MTAVAAPAIHDPTASRSLFASRVTVLLAIALSAFTMRSAVTSMAPLLARVADTMGFGGTVIGVFGMLPTA MFALAGFAAPLSRRFGPERLALLSVLATAAGTAGRSMASDTSELMAFTTLALVGMGIANIVIPPLVKKYF NDRVALMSAIYLACLQLGTIMPAVAAVPLAESYGWRASLAIWALIPAVAVLPWILVLVRRRTNGTDHAAR TGKKIGPIWRSPISWGLTFMFSMTSLITYAMFAWLPVIVTSAGGSEALGGAMVATFSGVGFLATLVTPRL CARAANPFPIVAASALCFLVGFAGLLWAPLTAPIVWAIFLGLGPSTFPAAITLINLRSRTESGSAALSGF TQGMGYLLASPGPLIFGILYNATGRWELSFGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSGSDAVED VVEGERLQECSTSCA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0750 | - | - | 100% (435) | MFS transporter |
| M. marinum M | MMAR_0093 | ermB | 6e-06 | 25.65% (386) | integral membrane efflux protein ErmB |
| M. marinum M | MMAR_2515 | - | 7e-05 | 25.81% (186) | integral membrane drug efflux protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1766c | narK2 | 2e-08 | 23.39% (372) | nitrate/nitrite transporter NarK2 |
| M. gilvum PYR-GCK | Mflv_0017 | - | 3e-57 | 33.33% (408) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1737c | narK2 | 2e-08 | 23.39% (372) | nitrate/nitrite transporter NarK2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2273 | - | 1e-128 | 56.03% (398) | MFS family transporter |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2795 | - | 3e-53 | 31.36% (389) | transmembrane transport protein |
| M. thermoresistible (build 8) | TH_0390 | - | 1e-09 | 25.60% (375) | major facilitator superfamily protein permease |
| M. ulcerans Agy99 | MUL_1382 | - | 0.0 | 99.77% (427) | MFS transporter |
| M. vanbaalenii PYR-1 | Mvan_0951 | - | 3e-57 | 31.39% (395) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1766c|M.bovis_AF2122/97 ---------------------------MRGQAANLVLATWISVVNFW-AW
Rv1737c|M.tuberculosis_H37Rv ---------------------------MRGQAANLVLATWISVVNFW-AW
MMAR_0750|M.marinum_M ----------MTAVAAPAIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
MUL_1382|M.ulcerans_Agy99 -----------------MIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
MAB_2273|M.abscessus_ATCC_1997 ----------MTATLRDETHMISAA-ALRRGRLMVLAAILLFALCLRSAV
Mflv_0017|M.gilvum_PYR-GCK -----MRSERQPMIVDPRATPDS-VPPVAGG-ALLAVAVVLAALNLRPAV
Mvan_0951|M.vanbaalenii_PYR-1 -----MRTERQEITTDPTLDPASRVPTVAGG-ALLAVAVVLTALNLRPAV
MSMEG_2795|M.smegmatis_MC2_155 MPRNSLDSYEHDLELEIDGAAEFRAPAMAAGGVLLAVAVVLTALNLRPAI
TH_0390|M.thermoresistible__bu ----------MNPGRRARTAAGDDDERLAVRPWIVWATGLLAYIVAVLDR
: : : : .
Mb1766c|M.bovis_AF2122/97 NLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRA
Rv1737c|M.tuberculosis_H37Rv NLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRA
MMAR_0750|M.marinum_M TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFG---
MUL_1382|M.ulcerans_Agy99 TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFG---
MAB_2273|M.abscessus_ATCC_1997 TSLSPLLTQISHEIGFGSAVIGVFGMLPTAMFAIAGLVTPALTERFG---
Mflv_0017|M.gilvum_PYR-GCK TSIATLLHDIRGDLAVSATWAGLVTTLPALCFAGAGLAAPWVASRIG---
Mvan_0951|M.vanbaalenii_PYR-1 TSIATVLGDIRAELSVSATWAGLLMTLPALCFAGAGFAAPWLAARVG---
MSMEG_2795|M.smegmatis_MC2_155 TSVGPLLGDMRSDLGASGVWAGVLTTMPGLCFAAAGLAAPWLARKLG---
TH_0390|M.thermoresistible__bu TTLGVSGLAAADRFNAAPAALSTFVVLQVIVYALAQVPAGLLLDRFG---
. :. : . . . . * . . : : :.*
Mb1766c|M.bovis_AF2122/97 MLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGVAGTIFAVGIPFAN
Rv1737c|M.tuberculosis_H37Rv MLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGVAGTIFAVGIPFAN
MMAR_0750|M.marinum_M PERLALLSVLATAAGTAGRSMASDTSELMAFTTLALVGMGIANIVIPPLV
MUL_1382|M.ulcerans_Agy99 PERLALLSVLATAAGTAGRSMASDTSELMAFTTLALVGMGIANIVVPPLV
MAB_2273|M.abscessus_ATCC_1997 LERTTLAAVVATVIGMAARTAMNSTGGLLVLSCLALLGMGIGNVVIPPLV
Mflv_0017|M.gilvum_PYR-GCK LSRAISVALLALTAGLALR-GVGGEYVVIGATLIACAGIALANVLIPVVI
Mvan_0951|M.vanbaalenii_PYR-1 LGRTISAAMVALTAGLALR-GAAGPHVIIGATLVACAGIALVNVLIPVVI
MSMEG_2795|M.smegmatis_MC2_155 LGWAISLAMGVLTVGLLVR-VLDGALVVLGGTLVATGGIALINVLIPVVI
TH_0390|M.thermoresistible__bu SKALIVAGAAVMATGQLILAFTESLTLAILARAIVGLGDAVTFISVLRLV
. . . . : . . : : :
Mb1766c|M.bovis_AF2122/97 NWYQPAR-RGFSTGVFGMGMVG-TALSAFFTPRFVRWFGLFTTHAIVAAA
Rv1737c|M.tuberculosis_H37Rv NWYQPAR-RGFSTGVFGMGMVG-TALSAFFTPRFVRWFGLFTTHAIVAAA
MMAR_0750|M.marinum_M KKYFNDR-VALMSAIYLACLQLGTIMPAVAAVPLAESYG-WRASLAIWAL
MUL_1382|M.ulcerans_Agy99 KKYFNDR-VALMSAIYLACLQLGTIMPAVAAVPLAESYG-WRASLAIWAL
MAB_2273|M.abscessus_ATCC_1997 KRYFSHR-VALMSAAYLTVLQIGTTVPALTAVPLADAYG-WRFSLVAWVL
Mflv_0017|M.gilvum_PYR-GCK KTSFPAR-IGMMTGIYTAALQGGGALGSAVTPGLADPLGGWRTALMVWAA
Mvan_0951|M.vanbaalenii_PYR-1 KGSFPAR-IGLMTGIYTAALQGGGALGSAVTPGLEEPLGGWRAAVAVWAV
MSMEG_2795|M.smegmatis_MC2_155 KGSFPAR-IGLMTGIYTAALQGGGALGSGVTSPLQDVLGGWREALGSWTV
TH_0390|M.thermoresistible__bu PHWFRPRQVPLVTQLTGICGQLGQVLSAVLFLALLTARGWTPAYLSVVAL
* : : : : : * .
Mb1766c|M.bovis_AF2122/97 LASTAVVAMVVLRDAPYFRPNADPVLP------RLKAAARLP-VTWEMSF
Rv1737c|M.tuberculosis_H37Rv LASTAVVAMVVLRDAPYFRPNADPVLP------RLKAAARLP-VTWEMSF
MMAR_0750|M.marinum_M IPAVAVLPWILVLVRRR-TNGTDHAAR---TGKKIGPIWRSP-ISWGLTF
MUL_1382|M.ulcerans_Agy99 IPAVAVLPWILVLVRRR-TNGTDHAAR---TGKKIGPIWRSP-ISWGLTF
MAB_2273|M.abscessus_ATCC_1997 VPVAALLPWIGVVIARRGHDVEDHSAEPHADSAAVGQVWRSP-LAWGMAG
Mflv_0017|M.gilvum_PYR-GCK VSLLALTLWIPATARHRSAWAVHTRPS-----AARRSLLRSP-LAWTVTV
Mvan_0951|M.vanbaalenii_PYR-1 VSLLALMVWIPATGRHRGAWAAHSLP------AGRRSLLRSP-LAWTITV
MSMEG_2795|M.smegmatis_MC2_155 LALAALVVWLLAARSIHGARTTPMTAS-----GKSRSLLRNP-LAWTVTL
TH_0390|M.thermoresistible__bu GVLTIALTLALVQNTPDGRAAPATMGTVREIAASLKTVWLRAGTRLGFFT
. .
Mb1766c|M.bovis_AF2122/97 LYAIVFGGFVAFSNYLPTYITTIYGFSTVDAGARTAGFALAAVLARPVGG
Rv1737c|M.tuberculosis_H37Rv LYAIVFGGFVAFSNYLPTYITTIYGFSTVDAGARTAGFALAAVLARPVGG
MMAR_0750|M.marinum_M MFSMTSLITYAMFAWLPVIVTSA-GGSEALGGAMVATFSGVGFLATLVTP
MUL_1382|M.ulcerans_Agy99 MFSMTSLITYAMFAWLPVIVTSA-GGSEALGGAMVATFSGVGFLATLVTP
MAB_2273|M.abscessus_ATCC_1997 MFGMTSLVTYSMFTWIPAILASA-GGSAKLGGVMVALFSAVGFVGTLAIP
Mflv_0017|M.gilvum_PYR-GCK FFGSQAFLAYIMMGWLPQVFIDN-GIDKVQAGLLVAVASLVGVPLSLVIT
Mvan_0951|M.vanbaalenii_PYR-1 FFGSQAFMAYIVMGWLPQVLVDN-GVDQVQAGLLVGLMSLIGVPISLLIA
MSMEG_2795|M.smegmatis_MC2_155 FFGCQAFLAYIVMGWLPEVFIDS-GVGKTQAGLLVGLVSLLAVPISLVVA
TH_0390|M.thermoresistible__bu HMGTQFSVTVFALMWGVPYLTVGQGLSTQMAGAMLTLSVAVAIVAGVLIG
. : . * . .* ..
Mb1766c|M.bovis_AF2122/97 WLSDRIAPRHV-VLASLAGTALLAFAAALQPPPEVWSAATFITLAVCLGV
Rv1737c|M.tuberculosis_H37Rv WLSDRIAPRHV-VLASLAGTALLAFAAALQPPPEVWSAATFITLAVCLGV
MMAR_0750|M.marinum_M RLCARAANPFP-IVAASALCFLVGFAGLLWAP-LTAPIVWAIFLGLGPST
MUL_1382|M.ulcerans_Agy99 RLCARAANPFP-IVAASALCFLVGFAGLLWAP-LTAPIVWAIFLGLGPST
MAB_2273|M.abscessus_ATCC_1997 PLAARMRNPFP-LVVACLVCFLIGFAGLLWLP-MHGTAVWVVALGFGPST
Mflv_0017|M.gilvum_PYR-GCK PLAARSASQSG-WIVGVGSFGFLGTVGLMVAP-TAQPLLWSVLLGTGLSG
Mvan_0951|M.vanbaalenii_PYR-1 PMAARRPSQSG-WIVAVGMFGFAGAIGLMVAP-AAQPLLWSVLIGIGMSA
MSMEG_2795|M.smegmatis_MC2_155 PLAARQSGQTG-WIVGLGVVGFAGMVGLLVDP-GAAPLLWSVLVGLGMSV
TH_0390|M.thermoresistible__bu IFTGRHPHRRSRLVLAIIASNAAAWTAVLALP-DRAPLWLLITLIVVISV
: * : . . . : * . : : .
Mb1766c|M.bovis_AF2122/97 GTGGVFA---WVARRAPAASVGSVTGIVAAAGGLGGYFPPLVMGATYDP-
Rv1737c|M.tuberculosis_H37Rv GTGGVFA---WVARRAPAASVGSVTGIVAAAGGLGGYFPPLVMGATYDP-
MMAR_0750|M.marinum_M FPAAITL---INLRSRTESGSAALSGFTQGMGYLLASPGPLIFGILYN--
MUL_1382|M.ulcerans_Agy99 FPAAITL---INLRSRTESGSAALSGFTQGMGYLLASPGPLIFGILYN--
MAB_2273|M.abscessus_ATCC_1997 FPLGLTL---VNLRTRTPAGSAALSGFTQGVGYAVACLGPLLFGVLHD--
Mflv_0017|M.gilvum_PYR-GCK FSLALAL---LGLRARTPEDTAALSGMAQGFGYLLAGTGPFLFGLLHD--
Mvan_0951|M.vanbaalenii_PYR-1 FSMALAV---LGLRARTAADTAQLSGMVQGFGYLIAGAGPFLFGLLHD--
MSMEG_2795|M.smegmatis_MC2_155 FSLALTV---IALRARTADDTAQLSGMAQGFGYLLAGFGPFLFGLLHD--
TH_0390|M.thermoresistible__bu GGPGSMVGFDFARTFNPSATLGTAQGMVNMGGFLASLLVMQAMGQILDAA
. . . *:. * . :* :
Mb1766c|M.bovis_AF2122/97 -------VDNDYTVGLLLLVATALVACTYTALHAREPVSEEASR------
Rv1737c|M.tuberculosis_H37Rv -------VDNDYTVGLLLLVATALVACTYTALHAREPVSEEASR------
MMAR_0750|M.marinum_M -------ATGRWELSFGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSG
MUL_1382|M.ulcerans_Agy99 -------ATGRWELSFGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSG
MAB_2273|M.abscessus_ATCC_1997 -------VSGGWYAPFGLLLVAITVLGVGAFQACKPRTLEDTWN----RG
Mflv_0017|M.gilvum_PYR-GCK -------VTHGWTAPWVLFLAVFCVQTVTGALAGRNRYV-----------
Mvan_0951|M.vanbaalenii_PYR-1 -------VSHGWTVPWMMFLAVYAVQIVAGALAGRARYV-----------
MSMEG_2795|M.smegmatis_MC2_155 -------VTGGWTAPWALVLAVYLVQMGAGALAGRNRYV-----------
TH_0390|M.thermoresistible__bu GGYSFDSFRLAWTVQYVVWVVAAVGILITRKKARRQMALEQERMLLESFE
: . :. :
Mb1766c|M.bovis_AF2122/97 ---------------------
Rv1737c|M.tuberculosis_H37Rv ---------------------
MMAR_0750|M.marinum_M SDAVEDVVEGERLQECSTSCA
MUL_1382|M.ulcerans_Agy99 SDAVEDVVEGERLQECSTSCA
MAB_2273|M.abscessus_ATCC_1997 SGAVVSS--------------
Mflv_0017|M.gilvum_PYR-GCK ---------------------
Mvan_0951|M.vanbaalenii_PYR-1 ---------------------
MSMEG_2795|M.smegmatis_MC2_155 ---------------------
TH_0390|M.thermoresistible__bu PGPRRHTGPDRTNRPHG----