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VAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMVVSLLATASSFLFINGVAFLI PSLQGARGIRLDEAGLLASMPSWGMVVTLVAWGYVLDRVGERVVMTTGSALTALAAYAASSAHSMVLIAV YLFLGGMAAASCNTAGGRLVSAWFPPHQRGLAMGIRQTAQPLGIALGAMVIPELAEHGPQAGLRFTALAC VFGAVASVIGIVDPPRKPRASASDQELASPYRGSLTLWRIHAVAGLMMMPQTVTVTFMLVWLIRNLHWSV AAAGALVTLSQLLGALGRVAVGRWSDRLGSRMRPVRYIAAAAVLVLLLLAWADYLNSRWQAGLMVAISVI AVLDNGLEATAITEFAGPYWSGRALGIQNTTQRMMAAAGPPLFGALISAAKYPPAWLLCALFPLAAMPLV PTRLLPPGLETRARRQSVRRLRWWRAVRSHALPDIVRRPGQPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3846 | - | - | 100% (463) | sugar transporter family protein |
| M. avium 104 | MAV_4059 | - | 2e-06 | 23.28% (421) | monoxygenase |
| M. avium 104 | MAV_1539 | - | 8e-05 | 24.12% (311) | major facilitator family protein transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3018 | - | 0.0 | 74.88% (434) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4231 | - | 1e-116 | 52.63% (399) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2994 | - | 0.0 | 74.88% (434) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3302 | - | 1e-122 | 53.81% (394) | major facilitator transporter |
| M. marinum M | MMAR_1717 | - | 1e-177 | 72.43% (428) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_2380 | - | 1e-125 | 57.73% (388) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_2039 | - | 1e-126 | 55.94% (404) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1468 | - | 2e-07 | 24.21% (190) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_2131 | - | 1e-121 | 56.52% (391) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3018|M.bovis_AF2122/97 -----------------------------MSRDPTG-----VGARWAIMI
Rv2994|M.tuberculosis_H37Rv -----------------------------MSRDPTG-----VGARWAIMI
MMAR_1717|M.marinum_M -----------------------------MPDESSATQELSLSARWWIVI
MAV_3846|M.avium_104 MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMV
Mflv_4231|M.gilvum_PYR-GCK ----------------------------------MAPSSIGPTRRWLMLA
Mvan_2131|M.vanbaalenii_PYR-1 --------------MSHIMRIWFSIVRRLCNHGAMPATAISSMRRWSMLA
MSMEG_2380|M.smegmatis_MC2_155 ------------------MELRFDILRSRDSMERMAAPVIGTLRRWSMLV
TH_2039|M.thermoresistible__bu ----------------------------------MPVSSISPARRWSMLV
MAB_3302|M.abscessus_ATCC_1997 ------------------------------MVTMVHVDEVGTARRWAMLA
MUL_1468|M.ulcerans_Agy99 ------------------------------------------MNRTQLLT
* ::
Mb3018|M.bovis_AF2122/97 VSLGVTASSFLFING--VAFLIPRLENARGTPLSHAGLLASMPSWGLVVT
Rv2994|M.tuberculosis_H37Rv VSLGVTASSFLFING--VAFLIPRLENARGTPLSHAGLLASMPSWGLVVT
MMAR_1717|M.marinum_M VSLIVTASSFLFING--VAFLIPRLENARDTPLAEAGLLASMPSWGMVVT
MAV_3846|M.avium_104 VSLLATASSFLFING--VAFLIPSLQGARGIRLDEAGLLASMPSWGMVVT
Mflv_4231|M.gilvum_PYR-GCK IGLLTTLCANVFING--VAFLIPTLHDERGLDLAGAALMSSLPSLGMVVT
Mvan_2131|M.vanbaalenii_PYR-1 IGLLATLCANVFING--VAFLIPTLHDERGLDLAAAGLMSSLPSLGMVVT
MSMEG_2380|M.smegmatis_MC2_155 IALTSTMCANVFING--AAFLIPTLHAERGLDLARSGLLSSMPSFGMVTT
TH_2039|M.thermoresistible__bu IALAATLFSVVFING--VAFVIPTLHREHGLSLAQAGLLSALPSFGMVAT
MAB_3302|M.abscessus_ATCC_1997 IALGSTAGANVFING--VAFLIPALHAERGLDLANAGLLSAMPSFGMVLT
MUL_1468|M.ulcerans_Agy99 IFATGLGLFMIFLDAFIVNVALPDIQNTFGVGEDGLQWVVAAYSLGMAVF
: :*::. . . :* :. . : : * *:.
Mb3018|M.bovis_AF2122/97 MFAWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMA
Rv2994|M.tuberculosis_H37Rv MFAWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMA
MMAR_1717|M.marinum_M LVAWGYVLDHVGEQIVMTVGSALTAIAAYAAASVDSLLLMGIYLFLGGMA
MAV_3846|M.avium_104 LVAWGYVLDRVGERVVMTTGSALTALAAYAASSAHSMVLIAVYLFLGGMA
Mflv_4231|M.gilvum_PYR-GCK LIAWGYVVDRIGERAVLTAGSALTAAASFAAASMDTLLTTGIFLFLGGMA
Mvan_2131|M.vanbaalenii_PYR-1 LIAWGYVVDRVGERVVLTLGSALTAAAAFAAAAADTLLTTGVFLFLGGMA
MSMEG_2380|M.smegmatis_MC2_155 LIAWGYVVDRFGERLVLGLGSALTAAAALAAASVQSLFAVGLFLLLGGMA
TH_2039|M.thermoresistible__bu LIAWGYLVDRIGERIVLTVGSALTAASAFAAAAVDSLLLVGVFLLLGGMA
MAB_3302|M.abscessus_ATCC_1997 LIAWGALIDKFGERIALVSGLALTAVAAFAAAESPSLTVTGAFLLLGGAA
MUL_1468|M.ulcerans_Agy99 IMSAATLADRYGRRRWYLMGIVLFTLGSIACGLAPSIAMLTAARGVQGFG
:.: . : *: *.: * .* : .: *.. :: : * .
Mb3018|M.bovis_AF2122/97 AGGCNSAGGRLVSGWFP-PQQRGLAMGIRQTAQPLGIASGALVIPELAE-
Rv2994|M.tuberculosis_H37Rv AGGCNSAGGRLVSGWFP-PQQRGLAMGIRQTAQPLGIASGALVIPELAE-
MMAR_1717|M.marinum_M AASCNSAGGRLVSGWFP-PHQRGLAMGIRQTAQPLGIALGALVIPELAE-
MAV_3846|M.avium_104 AASCNTAGGRLVSAWFP-PHQRGLAMGIRQTAQPLGIALGAMVIPELAE-
Mflv_4231|M.gilvum_PYR-GCK AASSNTASARLVVGWFD-AERRGLVMGIRQTAQPLGVGVGALVIPRLAES
Mvan_2131|M.vanbaalenii_PYR-1 AASSNTASGRLVVGWFD-AERRGLVMGIRQTAQPLGVGVGALVIPRLAQA
MSMEG_2380|M.smegmatis_MC2_155 AASSNSASGRLVVGWFP-PEQRGLVMGIRQTATPLGVGLGALVIPRLAES
TH_2039|M.thermoresistible__bu AASSNTASARVVVGWFP-PHQRGLVMGIRQTAQPLGVALGALVIPRLAQS
MAB_3302|M.abscessus_ATCC_1997 AAACNSASGRVVVGWFP-PHQRGTVMGIRQMAQPLGVAAGALVIPRIAEG
MUL_1468|M.ulcerans_Agy99 AATVSVTSLALVSAAFPNPKEKARAIGIWTAVASVGTATGPTLGGLLVDT
*. . :. :* . * ...:. .:** . .:* . *. : :.:
Mb3018|M.bovis_AF2122/97 RGVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSI
Rv2994|M.tuberculosis_H37Rv RGVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSI
MMAR_1717|M.marinum_M HSIHNALMFPAAFCTIAAVASLVGVVDPPRKSRKVASKEELASPYRGSAV
MAV_3846|M.avium_104 HGPQAGLRFTALACVFGAVASVIGIVDPPRKPRASASDQELASPYRGSLT
Mflv_4231|M.gilvum_PYR-GCK HGLSAALLFPAVVCAVSAVLCLAAVIDPPRPARADAARTDLANPYRNSAM
Mvan_2131|M.vanbaalenii_PYR-1 EGVSAALLFPAIVCAAAAVLCAIAVVDPPRPARAEADDTDLANPYRGSPM
MSMEG_2380|M.smegmatis_MC2_155 HGVSAALLFPAVVCGIAAVVSAVFVLDPPRPPRAEAPAEHLANPYRGSSV
TH_2039|M.thermoresistible__bu HGISAALLFPAAVCAVAAVICLIGVLDPPRPPRASADGRHPQNPYRGSGL
MAB_3302|M.abscessus_ATCC_1997 HGVATALLFPAIVCAVSSAVCLVGIIDPPRPPRSEAPEEHLANPYRGSRV
MUL_1468|M.ulcerans_Agy99 WGWRS-IFYVNVPMGVFVILLTVGFVAESRNARAGQLDLS----------
. : : .: .* .*
Mb3018|M.bovis_AF2122/97 LWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGAL
Rv2994|M.tuberculosis_H37Rv LWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGAL
MMAR_1717|M.marinum_M LWRIHASSALLMMPQTVTVTFMLVWLMNHHGWPVATAGILVTVSQLLGAL
MAV_3846|M.avium_104 LWRIHAVAGLMMMPQTVTVTFMLVWLIRNLHWSVAAAGALVTLSQLLGAL
Mflv_4231|M.gilvum_PYR-GCK LWRIHLTSVLLVIPQVVVWTFTLVWMISEHGWSPESAGVLVMVAQIMGAA
Mvan_2131|M.vanbaalenii_PYR-1 LWRIHLTSVLLVVPQVMVWTFTLVWLISEHRWSPESAGLLVMTAQILGAA
MSMEG_2380|M.smegmatis_MC2_155 LWRIHAVSVLLVVPQGVLWTFALVWLITDRGWSAASAGILVTVTQLLGAG
TH_2039|M.thermoresistible__bu LWRIHAVSVLLVVPQGVIWTFTLVWLMTERSWSAGSAGTMVMIAQVLGAG
MAB_3302|M.abscessus_ATCC_1997 LWLIHGVSVLLVVPQVVVWTFTLVWLVTDRGWSIGAASVMVTVAQLVGAL
MUL_1468|M.ulcerans_Agy99 ----------------------------------GQALFIVTVGAFVYAV
* :* .: *
Mb3018|M.bovis_AF2122/97 GRVAVGRWS--------DHVGSRMRPVRLIAAAAAATLFLLAAVDNEGSR
Rv2994|M.tuberculosis_H37Rv GRVAVGRWS--------DHVGSRMRPVRLIAAAAAATLFLLAAVDNEGSR
MMAR_1717|M.marinum_M GRIAVGRWS--------DRVGSRMRPVRVIAIASAAALFLLALVDDEGSR
MAV_3846|M.avium_104 GRVAVGRWS--------DRLGSRMRPVRYIAAAAVLVLLLLAWADYLNSR
Mflv_4231|M.gilvum_PYR-GCK GRIGAGRWSDHYVRRSGDLLASRLRPIRIIAAAAAASMALLALTDLVNSP
Mvan_2131|M.vanbaalenii_PYR-1 GRIGAGRWSDTFVRRSGDVIASRLRPIRMIAAAAAAAMALLAVTDWLDSP
MSMEG_2380|M.smegmatis_MC2_155 GRIAAGKWS--------DVIGYRLRPIRTIALAAAVTMAALALTDWLSSP
TH_2039|M.thermoresistible__bu GRVAAGRWS--------DLVGSRLRPIRTIALAAAAAMALLALTDALDSP
MAB_3302|M.abscessus_ATCC_1997 GRVAAGMWS--------DRWGSRMRPIRAIAAAASATMALLAVTNQLDWS
MUL_1468|M.ulcerans_Agy99 IEGPQIGWT------------SPLILTLLMTAIVGCALFLWLEGRSADP-
. *: : :: : .
Mb3018|M.bovis_AF2122/97 YDVLLMIAISVIAVLDNGLEATAITEYAGPYWSGRALGIQNTTQRLMAAA
Rv2994|M.tuberculosis_H37Rv YDVLLMIAISVIAVLDNGLEATAITEYAGPYWSGRALGIQNTTQRLMAAA
MMAR_1717|M.marinum_M YDVLLMITITVIAVLDNGLQATAITEYAGPYWSGRALGVQNTTQRLMAAA
MAV_3846|M.avium_104 WQAGLMVAISVIAVLDNGLEATAITEFAGPYWSGRALGIQNTTQRMMAAA
Mflv_4231|M.gilvum_PYR-GCK LSIALMMVASVITVSDNGLAFTLIAEYAGPFWSGRALGTQNTSQLFAQGV
Mvan_2131|M.vanbaalenii_PYR-1 VSIVVMIAASVITVSDNGLAFTLIAEYAGPFWSGRALGTQNTSQLFAQGV
MSMEG_2380|M.smegmatis_MC2_155 VSIALMVAASVITVSDNGLAFTGIAEIAGPFWSGRALGTQNTSQHLATAV
TH_2039|M.thermoresistible__bu VSVAFMVIAAVVTVSDNSLAFTAIAEIAGPYWTGRALGTQNTSQLLTTAI
MAB_3302|M.abscessus_ATCC_1997 VSVVVMLVASVITVSDNGLAYTSIAEIAGPFWSGRALGAQNTGQLLAAAV
MUL_1468|M.ulcerans_Agy99 -----MMDLTLFRDSSYALSIGTICTVFFAVYGMLLLTTQ----------
*: ::. . .* * . : * *
Mb3018|M.bovis_AF2122/97 GPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRARRQSV
Rv2994|M.tuberculosis_H37Rv GPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRARRQSV
MMAR_1717|M.marinum_M GPPIFGALITTAAYPLAWGLCGLFPLAAIPLVPTRLRPPGLEPRERPQSA
MAV_3846|M.avium_104 GPPLFGALISAAKYPPAWLLCALFPLAAMPLVPTRLLPPGLETRARRQSV
Mflv_4231|M.gilvum_PYR-GCK APPLFGGLIAVAGYPVAFAVCALLPVLAIPAVPLKVTVDR----------
Mvan_2131|M.vanbaalenii_PYR-1 APPLFGGLIAIAGYPVAFAVCALFPLLAIPSVPLTVKPDR----------
MSMEG_2380|M.smegmatis_MC2_155 SSPVFGGLIGVAGYPVAFAVCALLPALAIPLVPVEPARES----------
TH_2039|M.thermoresistible__bu TPPLFGGLIGVAGYPVAFALCAVLPLAAVPLVPADPATPQIRPSSPESPR
MAB_3302|M.abscessus_ATCC_1997 APPIFGAIAAAAGFSAAFAVCALFPLAAVGLVPVKLERPAP---------
MUL_1468|M.ulcerans_Agy99 ------FLHNVRGYTQGSGVVD----------------------------
: :. . :
Mb3018|M.bovis_AF2122/97 RRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAITPPT
Rv2994|M.tuberculosis_H37Rv RRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAITPPT
MMAR_1717|M.marinum_M RRLRRWQAVRSRELPSNPRPPDPPG----------------
MAV_3846|M.avium_104 RRLRWWRAVRSHALPDIVRRPGQPG----------------
Mflv_4231|M.gilvum_PYR-GCK -----------------------------------------
Mvan_2131|M.vanbaalenii_PYR-1 -----------------------------------------
MSMEG_2380|M.smegmatis_MC2_155 -----------------------------------------
TH_2039|M.thermoresistible__bu RVR--------------------------------------
MAB_3302|M.abscessus_ATCC_1997 -----------------------------------------
MUL_1468|M.ulcerans_Agy99 -----------------------------------------