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VTATLRDETHMISAAALRRGRLMVLAAILLFALCLRSAVTSLSPLLTQISHEIGFGSAVIGVFGMLPTAM FAIAGLVTPALTERFGLERTTLAAVVATVIGMAARTAMNSTGGLLVLSCLALLGMGIGNVVIPPLVKRYF SHRVALMSAAYLTVLQIGTTVPALTAVPLADAYGWRFSLVAWVLVPVAALLPWIGVVIARRGHDVEDHSA EPHADSAAVGQVWRSPLAWGMAGMFGMTSLVTYSMFTWIPAILASAGGSAKLGGVMVALFSAVGFVGTLA IPPLAARMRNPFPLVVACLVCFLIGFAGLLWLPMHGTAVWVVALGFGPSTFPLGLTLVNLRTRTPAGSAA LSGFTQGVGYAVACLGPLLFGVLHDVSGGWYAPFGLLLVAITVLGVGAFQACKPRTLEDTWNRGSGAVVS S
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2273 | - | - | 100% (421) | MFS family transporter |
| M. abscessus ATCC 19977 | MAB_2706c | - | 4e-07 | 22.91% (419) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1766c | narK2 | 1e-06 | 20.73% (381) | nitrate/nitrite transporter NarK2 |
| M. gilvum PYR-GCK | Mflv_0017 | - | 1e-56 | 36.77% (378) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1877 | - | 6e-07 | 23.16% (393) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0750 | - | 1e-128 | 56.03% (398) | MFS transporter |
| M. avium 104 | MAV_2832 | - | 2e-05 | 24.41% (340) | drug transporter |
| M. smegmatis MC2 155 | MSMEG_2795 | - | 5e-57 | 35.22% (389) | transmembrane transport protein |
| M. thermoresistible (build 8) | TH_3988 | - | 7e-09 | 24.48% (286) | PUTATIVE putative MFS permease |
| M. ulcerans Agy99 | MUL_1382 | - | 1e-128 | 55.78% (398) | MFS transporter |
| M. vanbaalenii PYR-1 | Mvan_0951 | - | 2e-55 | 34.63% (387) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0750|M.marinum_M ----------MTAVAAPAIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
MUL_1382|M.ulcerans_Agy99 -----------------MIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
MAB_2273|M.abscessus_ATCC_1997 ----------MTATLRDETHMISAA-ALRRGRLMVLAAILLFALCLRSAV
Mflv_0017|M.gilvum_PYR-GCK -----MRSERQPMIVDPRATPDS-VPPVAGG-ALLAVAVVLAALNLRPAV
Mvan_0951|M.vanbaalenii_PYR-1 -----MRTERQEITTDPTLDPASRVPTVAGG-ALLAVAVVLTALNLRPAV
MSMEG_2795|M.smegmatis_MC2_155 MPRNSLDSYEHDLELEIDGAAEFRAPAMAAGGVLLAVAVVLTALNLRPAI
Rv1877|M.tuberculosis_H37Rv ------MAGPTAPTTAPTAIRAGGPLLSPVRRNIIFTALVFGVLVAATGQ
MAV_2832|M.avium_104 ------MNAPARADTG-----SGGERISPQRRNLIFVAIVLGMLLAALDQ
Mb1766c|M.bovis_AF2122/97 ----------------------------MRGQAANLVLATWISVVNFWAW
TH_3988|M.thermoresistible__bu ------MSESKASQDASAPAADPVDATARRTPWIAILAAALGIFVMITIE
.
MMAR_0750|M.marinum_M TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFGPER
MUL_1382|M.ulcerans_Agy99 TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFGPER
MAB_2273|M.abscessus_ATCC_1997 TSLSPLLTQISHEIGFGSAVIGVFGMLPTAMFAIAGLVTPALTERFGLER
Mflv_0017|M.gilvum_PYR-GCK TSIATLLHDIRGDLAVSATWAGLVTTLPALCFAGAGLAAPWVASRIGLSR
Mvan_0951|M.vanbaalenii_PYR-1 TSIATVLGDIRAELSVSATWAGLLMTLPALCFAGAGFAAPWLAARVGLGR
MSMEG_2795|M.smegmatis_MC2_155 TSVGPLLGDMRSDLGASGVWAGVLTTMPGLCFAAAGLAAPWLARKLGLGW
Rv1877|M.tuberculosis_H37Rv TIVVPALPTIVAELGSTVDQSWAVTSYLLGGTVVVVVAGK-LGDLLGRNR
MAV_2832|M.avium_104 TIVATALPTIVANLGDAGHQSWVVTSYLLASTIVTALVGK-LGDLYGRKR
Mb1766c|M.bovis_AF2122/97 NLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRA
TH_3988|M.thermoresistible__bu ELPIGVLTLIGDDLGLSSGVVGLTVTIPGVLAGAVAVLTPTLIGRLDRRL
:. . : .
MMAR_0750|M.marinum_M LALLSVLATAAGTAGRSMASDT---SELMAFTTLALVGMGIANIVIPPLV
MUL_1382|M.ulcerans_Agy99 LALLSVLATAAGTAGRSMASDT---SELMAFTTLALVGMGIANIVVPPLV
MAB_2273|M.abscessus_ATCC_1997 TTLAAVVATVIGMAARTAMNST---GGLLVLSCLALLGMGIGNVVIPPLV
Mflv_0017|M.gilvum_PYR-GCK AISVALLALTAGLALR-GVGGE---YVVIGATLIACAGIALANVLIPVVI
Mvan_0951|M.vanbaalenii_PYR-1 TISAAMVALTAGLALR-GAAGP---HVIIGATLVACAGIALVNVLIPVVI
MSMEG_2795|M.smegmatis_MC2_155 AISLAMGVLTVGLLVR-VLDGA---LVVLGGTLVATGGIALINVLIPVVI
Rv1877|M.tuberculosis_H37Rv VLLGSVVVFVVGSVLCGLSQTM---TMLAISRALQGVGAGAISVTAYALA
MAV_2832|M.avium_104 VFQAAVLFFVAGSVLCGLAQSM---AMLVGARALQGIGGGGITVTASALI
Mb1766c|M.bovis_AF2122/97 MLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGVAGTIFAVGIPFAN
TH_3988|M.thermoresistible__bu ALVSALLLVFVSAATSAIAPNLP---VLLASRLFAGMAIGVFWALLAVVV
: . .
MMAR_0750|M.marinum_M KKYFNDR-VALMSAIYLACLQLGTIMPAVAAVPLAESYG-WRASLAIWAL
MUL_1382|M.ulcerans_Agy99 KKYFNDR-VALMSAIYLACLQLGTIMPAVAAVPLAESYG-WRASLAIWAL
MAB_2273|M.abscessus_ATCC_1997 KRYFSHR-VALMSAAYLTVLQIGTTVPALTAVPLADAYG-WRFSLVAWVL
Mflv_0017|M.gilvum_PYR-GCK KTSFPAR-IGMMTGIYTAALQGGGALGSAVTPGLADPLGGWRTALMVWAA
Mvan_0951|M.vanbaalenii_PYR-1 KGSFPAR-IGLMTGIYTAALQGGGALGSAVTPGLEEPLGGWRAAVAVWAV
MSMEG_2795|M.smegmatis_MC2_155 KGSFPAR-IGLMTGIYTAALQGGGALGSGVTSPLQDVLGGWREALGSWTV
Rv1877|M.tuberculosis_H37Rv AEVVPLRDRGRYQGVLGAVFGVNTVTGPLLGGWLTDYLS-WRWAFWINVP
MAV_2832|M.avium_104 GEVVPLRERGRYQGILGAVFGVTTVIGPLLGGYFTDYLS-WRWAFWVNVP
Mb1766c|M.bovis_AF2122/97 NWYQPAR-----RGFSTGVFGMG-MVGTALSAFFTPRFVRWFGLFTTHAI
TH_3988|M.thermoresistible__bu ARVAHPDDLPKALTLAFGGVSVAVVLGVPFAAWIGAMVG-WRWAFVLVGA
. : * .
MMAR_0750|M.marinum_M IPAVAVLPWILVLVRRR-TNGTDHAAR---TGKKIGPIWRSPISWG----
MUL_1382|M.ulcerans_Agy99 IPAVAVLPWILVLVRRR-TNGTDHAAR---TGKKIGPIWRSPISWG----
MAB_2273|M.abscessus_ATCC_1997 VPVAALLPWIGVVIARRGHDVEDHSAEPHADSAAVGQVWRSPLAWG----
Mflv_0017|M.gilvum_PYR-GCK VSLLALTLWIPATARHRSAWAVHTRPS-----AARRSLLRSPLAWT----
Mvan_0951|M.vanbaalenii_PYR-1 VSLLALMVWIPATGRHRGAWAAHSLP------AGRRSLLRSPLAWT----
MSMEG_2795|M.smegmatis_MC2_155 LALAALVVWLLAARSIHGARTTPMTAS-----GKSRSLLRNPLAWT----
Rv1877|M.tuberculosis_H37Rv VSIAVLTVAATAVPALARPPKPVIDYLGILVIAVATTALIMATSWGGTTY
MAV_2832|M.avium_104 VSVIVIFVAAAAIPALAASAKPVIDYAGIVFVGLGAAGLTLATSWGGSRY
Mb1766c|M.bovis_AF2122/97 VAAALASTAVVAMVVLRDAPYFRPNADP--VLPRLKAAARLPVTWEMS--
TH_3988|M.thermoresistible__bu LGLMVAVALTVLLPPVPVAERTTLGQLG--------AAWSIPAARTG---
: . :
MMAR_0750|M.marinum_M --------------------------------------LTFMFSMTSLIT
MUL_1382|M.ulcerans_Agy99 --------------------------------------LTFMFSMTSLIT
MAB_2273|M.abscessus_ATCC_1997 --------------------------------------MAGMFGMTSLVT
Mflv_0017|M.gilvum_PYR-GCK --------------------------------------VTVFFGSQAFLA
Mvan_0951|M.vanbaalenii_PYR-1 --------------------------------------ITVFFGSQAFMA
MSMEG_2795|M.smegmatis_MC2_155 --------------------------------------VTLFFGCQAFLA
Rv1877|M.tuberculosis_H37Rv AWGSATIVGLLIGAAVALGFFVWLEGRAAAAILPPRLFGSPVFAVCCVLS
MAV_2832|M.avium_104 PWGSPTIIGLFAAAAVALGVFVVVERRAAEPILPVRLFASPVFTVCCVLS
Mb1766c|M.bovis_AF2122/97 --------------------------------------FLYAIVFGGFVA
TH_3988|M.thermoresistible__bu ------------------------------------VLVTLVMVTAHFTA
: . :
MMAR_0750|M.marinum_M YAM-------FAWLPVIVTSAGGSEALGGAMVATFSGVGFLATLVTPRLC
MUL_1382|M.ulcerans_Agy99 YAM-------FAWLPVIVTSAGGSEALGGAMVATFSGVGFLATLVTPRLC
MAB_2273|M.abscessus_ATCC_1997 YSM-------FTWIPAILASAGGSAKLGGVMVALFSAVGFVGTLAIPPLA
Mflv_0017|M.gilvum_PYR-GCK YIM-------MGWLPQVFIDNGIDKVQAGLLVAVASLVGVPLSLVITPLA
Mvan_0951|M.vanbaalenii_PYR-1 YIV-------MGWLPQVLVDNGVDQVQAGLLVGLMSLIGVPISLLIAPMA
MSMEG_2795|M.smegmatis_MC2_155 YIV-------MGWLPEVFIDSGVGKTQAGLLVGLVSLLAVPISLVVAPLA
Rv1877|M.tuberculosis_H37Rv FVVGFAMLGALTFVPIYLGYVDGASATASGLRTLPMVIGLLIASTGTGVL
MAV_2832|M.avium_104 FVVGFAMLGAMTFLPTYMQYVDGVSATTSGLRTLPMVVGMLFTSTGSGTI
Mb1766c|M.bovis_AF2122/97 FSN---------YLPTYITTIYGFSTVDAGARTAGFALAAVLARPVGGWL
TH_3988|M.thermoresistible__bu YTY---------ASPVLQDRIHITESGVGPMLFVFGIAGFLGNFAAGPLL
: * . .
MMAR_0750|M.marinum_M ARAANPFPIVAASALCFLVGFAGLL--WAPLTAPIVWAIFLGLGPSTFPA
MUL_1382|M.ulcerans_Agy99 ARAANPFPIVAASALCFLVGFAGLL--WAPLTAPIVWAIFLGLGPSTFPA
MAB_2273|M.abscessus_ATCC_1997 ARMRNPFPLVVACLVCFLIGFAGLL--WLPMHGTAVWVVALGFGPSTFPL
Mflv_0017|M.gilvum_PYR-GCK ARSASQSGWIVGVGSFGFLGTVGLM--VAPTAQPLLWSVLLGTGLSGFSL
Mvan_0951|M.vanbaalenii_PYR-1 ARRPSQSGWIVAVGMFGFAGAIGLM--VAPAAQPLLWSVLIGIGMSAFSM
MSMEG_2795|M.smegmatis_MC2_155 ARQSGQTGWIVGLGVVGFAGMVGLL--VDPGAAPLLWSVLVGLGMSVFSL
Rv1877|M.tuberculosis_H37Rv VGRTGRYKIFPVAGMALMAVAFLLMSQMDEWTPPLLQSLYLVVLGAGIGL
MAV_2832|M.avium_104 VGRTGRYKIFPVAGTALMALAFLLMSRMQPSTSAVIQSLYLFILGAGIGL
Mb1766c|M.bovis_AF2122/97 SDRIAPRHVVLASLAGTALLAFAAALQPPPEVWSAATFITLAVCLGVGTG
TH_3988|M.thermoresistible__bu RRSMRATYVVLPIGVMVGVXXXGPNSRWRPDGTRM---------------
.
MMAR_0750|M.marinum_M AITLINLRSRTESGSAALSGFTQGMGYLLAS---PGPLIFG---------
MUL_1382|M.ulcerans_Agy99 AITLINLRSRTESGSAALSGFTQGMGYLLAS---PGPLIFG---------
MAB_2273|M.abscessus_ATCC_1997 GLTLVNLRTRTPAGSAALSGFTQGVGYAVAC---LGPLLFG---------
Mflv_0017|M.gilvum_PYR-GCK ALALLGLRARTPEDTAALSGMAQGFGYLLAG---TGPFLFG---------
Mvan_0951|M.vanbaalenii_PYR-1 ALAVLGLRARTAADTAQLSGMVQGFGYLIAG---AGPFLFG---------
MSMEG_2795|M.smegmatis_MC2_155 ALTVIALRARTADDTAQLSGMAQGFGYLLAG---FGPFLFG---------
Rv1877|M.tuberculosis_H37Rv SMQVLVLIVQNTSSFEDLGVATSGVTFFRVVGASFGTATFGALFVNFLDR
MAV_2832|M.avium_104 SMQVLILIVQNTSDFEDLGVATSGVTFFRTIGSSFGAAIFGSLFVNFLNR
Mb1766c|M.bovis_AF2122/97 GVFAWVARRAPAASVGSVTGIVAAAGGLGGY---FPPLVMG---------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MMAR_0750|M.marinum_M --------------------ILYNATGRWELSFG---------FLLVPLI
MUL_1382|M.ulcerans_Agy99 --------------------ILYNATGRWELSFG---------FLLVPLI
MAB_2273|M.abscessus_ATCC_1997 --------------------VLHDVSGGWYAPFG---------LLLVAIT
Mflv_0017|M.gilvum_PYR-GCK --------------------LLHDVTHGWTAPWV---------LFLAVFC
Mvan_0951|M.vanbaalenii_PYR-1 --------------------LLHDVSHGWTVPWM---------MFLAVYA
MSMEG_2795|M.smegmatis_MC2_155 --------------------LLHDVTGGWTAPWA---------LVLAVYL
Rv1877|M.tuberculosis_H37Rv RLGSALTSGAVPVPAVPSPAVLHQLPQSMAAPIVRAYAESLTQVFLCAVS
MAV_2832|M.avium_104 RIGPALAASGAPPGAVSSPGALHRQPHEVAAPIVAAYAESLTEVFFWAAP
Mb1766c|M.bovis_AF2122/97 ---------------------ATYDPVDNDYTVG---------LLLLVAT
TH_3988|M.thermoresistible__bu --------------------------------------------------
MMAR_0750|M.marinum_M ALLAGGYHACKPRYLEDTLTPSRKSGSDAVEDVVEGERLQECSTSCA---
MUL_1382|M.ulcerans_Agy99 ALLAGGYHACKPRYLEDTLTPSRKSGSDAVEDVVEGERLQECSTSCA---
MAB_2273|M.abscessus_ATCC_1997 VLGVGAFQACKPRTLEDTWN----RGSGAVVSS-----------------
Mflv_0017|M.gilvum_PYR-GCK VQTVTGALAGRNRYV-----------------------------------
Mvan_0951|M.vanbaalenii_PYR-1 VQIVAGALAGRARYV-----------------------------------
MSMEG_2795|M.smegmatis_MC2_155 VQMGAGALAGRNRYV-----------------------------------
Rv1877|M.tuberculosis_H37Rv VTVVGFILALLLREVPLTDIHDDADDLGDGFGVPRAESPEDVLEIAVRRM
MAV_2832|M.avium_104 VALVGFVLALFLREIPLRDIHDSTVDLGDAFGMPTTETPDQMLENAIARM
Mb1766c|M.bovis_AF2122/97 ALVACTYTALHAREPVSEEASR----------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MMAR_0750|M.marinum_M --------------------------------------------------
MUL_1382|M.ulcerans_Agy99 --------------------------------------------------
MAB_2273|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0017|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0951|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2795|M.smegmatis_MC2_155 --------------------------------------------------
Rv1877|M.tuberculosis_H37Rv LP--NGVRLRDIATQPGCGLGVAELWALLRIYQYQRLFEAVRLTDIGRHL
MAV_2832|M.avium_104 LRGETGMRLRSIAMRPDCRLDVAGLWGVLRINRYTQMYGTARLTDMAEYL
Mb1766c|M.bovis_AF2122/97 --------------------------------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MMAR_0750|M.marinum_M --------------------------------------------------
MUL_1382|M.ulcerans_Agy99 --------------------------------------------------
MAB_2273|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0017|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0951|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2795|M.smegmatis_MC2_155 --------------------------------------------------
Rv1877|M.tuberculosis_H37Rv HVPYQVFEPVFDRLVQTGYAARDGDILTLTPSGHRQVDSLAVLIRQWLLD
MAV_2832|M.avium_104 RIPFEVLEPTFSRLVTAGYAGSDGDRLWLTPAGAQQVGYVHSLLLAWLVD
Mb1766c|M.bovis_AF2122/97 --------------------------------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MMAR_0750|M.marinum_M --------------------------------------------------
MUL_1382|M.ulcerans_Agy99 --------------------------------------------------
MAB_2273|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0017|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0951|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2795|M.smegmatis_MC2_155 --------------------------------------------------
Rv1877|M.tuberculosis_H37Rv HLAVAPGLKRQPD-HQFEAALQHVTDAVLVQRDWYEDLGDLSESRQLAAT
MAV_2832|M.avium_104 KLGRSPGFEGRPDRQAVQAALERVAYRVLAQRDWHDAQPTAAIT---AAA
Mb1766c|M.bovis_AF2122/97 --------------------------------------------------
TH_3988|M.thermoresistible__bu --------------------------------------------------
MMAR_0750|M.marinum_M -
MUL_1382|M.ulcerans_Agy99 -
MAB_2273|M.abscessus_ATCC_1997 -
Mflv_0017|M.gilvum_PYR-GCK -
Mvan_0951|M.vanbaalenii_PYR-1 -
MSMEG_2795|M.smegmatis_MC2_155 -
Rv1877|M.tuberculosis_H37Rv T
MAV_2832|M.avium_104 R
Mb1766c|M.bovis_AF2122/97 -
TH_3988|M.thermoresistible__bu -