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VPRNSLDSYEHDLELEIDGAAEFRAPAMAAGGVLLAVAVVLTALNLRPAITSVGPLLGDMRSDLGASGVW AGVLTTMPGLCFAAAGLAAPWLARKLGLGWAISLAMGVLTVGLLVRVLDGALVVLGGTLVATGGIALINV LIPVVIKGSFPARIGLMTGIYTAALQGGGALGSGVTSPLQDVLGGWREALGSWTVLALAALVVWLLAARS IHGARTTPMTASGKSRSLLRNPLAWTVTLFFGCQAFLAYIVMGWLPEVFIDSGVGKTQAGLLVGLVSLLA VPISLVVAPLAARQSGQTGWIVGLGVVGFAGMVGLLVDPGAAPLLWSVLVGLGMSVFSLALTVIALRART ADDTAQLSGMAQGFGYLLAGFGPFLFGLLHDVTGGWTAPWALVLAVYLVQMGAGALAGRNRYV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2795 | - | - | 100% (413) | transmembrane transport protein |
| M. smegmatis MC2 155 | MSMEG_6513 | - | 9e-07 | 24.29% (354) | membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_3283 | - | 2e-06 | 26.65% (379) | membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0017 | - | 1e-144 | 66.93% (384) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv3021c | PPE47 | 8e-05 | 28.24% (131) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2273 | - | 3e-57 | 35.22% (389) | MFS family transporter |
| M. marinum M | MMAR_0750 | - | 3e-53 | 31.36% (389) | MFS transporter |
| M. avium 104 | MAV_1539 | - | 7e-07 | 26.28% (411) | major facilitator family protein transporter |
| M. thermoresistible (build 8) | TH_2968 | - | 1e-05 | 25.85% (236) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_1382 | - | 3e-53 | 31.11% (389) | MFS transporter |
| M. vanbaalenii PYR-1 | Mvan_0951 | - | 1e-148 | 66.67% (390) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0017|M.gilvum_PYR-GCK -----MRSERQPMIVDPRATPDS-VPPVAGG-ALLAVAVVLAALNLRPAV
Mvan_0951|M.vanbaalenii_PYR-1 -----MRTERQEITTDPTLDPASRVPTVAGG-ALLAVAVVLTALNLRPAV
MSMEG_2795|M.smegmatis_MC2_155 MPRNSLDSYEHDLELEIDGAAEFRAPAMAAGGVLLAVAVVLTALNLRPAI
MMAR_0750|M.marinum_M ----------MTAVAAPAIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
MUL_1382|M.ulcerans_Agy99 -----------------MIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
MAB_2273|M.abscessus_ATCC_1997 ----------MTATLRDETHMISAA-ALRRGRLMVLAAILLFALCLRSAV
TH_2968|M.thermoresistible__bu ------------------VRRDAPSGTPVRRPFLLVTALAVVVLTVAVLQ
MAV_1539|M.avium_104 ---------------MVMPNGPVAHQAGTRGYRRMTAALCGAGLASFAAM
Rv3021c|M.tuberculosis_H37Rv -----------------MVGAASADSAAAAGEHEAAAAGYVCALAEMPTL
. * :
Mflv_0017|M.gilvum_PYR-GCK TSIATLLHDIRGDLAVSATWAGLVTTLPALCFAGAGLAAPWVASRIGLSR
Mvan_0951|M.vanbaalenii_PYR-1 TSIATVLGDIRAELSVSATWAGLLMTLPALCFAGAGFAAPWLAARVGLGR
MSMEG_2795|M.smegmatis_MC2_155 TSVGPLLGDMRSDLGASGVWAGVLTTMPGLCFAAAGLAAPWLARKLGLGW
MMAR_0750|M.marinum_M TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFGPER
MUL_1382|M.ulcerans_Agy99 TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFGPER
MAB_2273|M.abscessus_ATCC_1997 TSLSPLLTQISHEIGFGSAVIGVFGMLPTAMFAIAGLVTPALTERFGLER
TH_2968|M.thermoresistible__bu TAVVPVLGIMAEQLHTSATAVSWAVTANLLAAAAATPLLGRLADLYSKRR
MAV_1539|M.avium_104 YCTQALLPALSAHHRIGPATAALTVSLTTGALALSIIPASVLSERYGRTR
Rv3021c|M.tuberculosis_H37Rv P-------------ELAANHLTHAVLVATNFFGINTIPIALNEADYVRMW
. .
Mflv_0017|M.gilvum_PYR-GCK AISVA-LLALTAGLALR-GVGGEYVVIGATLIACAGIALANVLIPVVIKT
Mvan_0951|M.vanbaalenii_PYR-1 TISAA-MVALTAGLALR-GAAGPHVIIGATLVACAGIALVNVLIPVVIKG
MSMEG_2795|M.smegmatis_MC2_155 AISLA-MGVLTVGLLVR-VLDGALVVLGGTLVATGGIALINVLIPVVIKG
MMAR_0750|M.marinum_M LALLS-VLATAAGTAGRSMASDTSELMAFTTLALVGMGIANIVIPPLVKK
MUL_1382|M.ulcerans_Agy99 LALLS-VLATAAGTAGRSMASDTSELMAFTTLALVGMGIANIVVPPLVKK
MAB_2273|M.abscessus_ATCC_1997 TTLAA-VVATVIGMAARTAMNSTGGLLVLSCLALLGMGIGNVVIPPLVKR
TH_2968|M.thermoresistible__bu VLLAV-LVVVLAGSVLAATTASLPLLITARVLQGASFALYPISIAILRDE
MAV_1539|M.avium_104 VMLISGVASSVIGLLLPFSPSLGVLVFGRAVQGVALAGIPAVAMALLAEE
Rv3021c|M.tuberculosis_H37Rv VQAAT--VMSAYEAVVGAALVATPHTGPAPVIVKPGANEASNAVAAATIT
:.
Mflv_0017|M.gilvum_PYR-GCK SFPARIGMMTGIYTAALQGGGALGSAVTPGLADPLGGWRTALMVWAAVSL
Mvan_0951|M.vanbaalenii_PYR-1 SFPARIGLMTGIYTAALQGGGALGSAVTPGLEEPLGGWRAAVAVWAVVSL
MSMEG_2795|M.smegmatis_MC2_155 SFPARIGLMTGIYTAALQGGGALGSGVTSPLQDVLGGWREALGSWTVLAL
MMAR_0750|M.marinum_M YFNDRVALMSAIYLACLQLGTIMPAVAAVPLAESYG-WRASLAIWALIPA
MUL_1382|M.ulcerans_Agy99 YFNDRVALMSAIYLACLQLGTIMPAVAAVPLAESYG-WRASLAIWALIPA
MAB_2273|M.abscessus_ATCC_1997 YFSHRVALMSAAYLTVLQIGTTVPALTAVPLADAYG-WRFSLVAWVLVPV
TH_2968|M.thermoresistible__bu LPPDRLGRAMAVMSGTLGFGGGAGLVVTGLLMTDGAVYQRVFWLCTAFTL
MAV_1539|M.avium_104 VDASSLGSAMGRYIAGTTIGGLAGRIVPS-VVVQVGTWRVALLACSLITL
Rv3021c|M.tuberculosis_H37Rv PFP------FGELAKFLEMAAQAFTEVGELIMKSAEAWAVGFVELITG-L
. . . : : .
Mflv_0017|M.gilvum_PYR-GCK LALTLWIPATARHRSAWAVHTRPS--------------------------
Mvan_0951|M.vanbaalenii_PYR-1 LALMVWIPATGRHRGAWAAHSLP---------------------------
MSMEG_2795|M.smegmatis_MC2_155 AALVVWLLAARSIHGARTTPMTAS--------------------------
MMAR_0750|M.marinum_M VAVLPWILVLVRRR-TNGTDHAAR--------------------------
MUL_1382|M.ulcerans_Agy99 VAVLPWILVLVRRR-TNGTDHAAR--------------------------
MAB_2273|M.abscessus_ATCC_1997 AALLPWIGVVIARRGHDVEDHSAEPHA-----------------------
TH_2968|M.thermoresistible__bu AVIVIAVLIVPVRHRRATGTLDWFGAAGLALGLSLGLLAITQGSHWGWTS
MAV_1539|M.avium_104 AGTAVFAVLVPRSRFFTPKPASVR--------------------------
Rv3021c|M.tuberculosis_H37Rv VNFEPWLVLT----------------------------------------
Mflv_0017|M.gilvum_PYR-GCK ----------------------------AARRSLLRSPLAWT--VTVFFG
Mvan_0951|M.vanbaalenii_PYR-1 ----------------------------AGRRSLLRSPLAWT--ITVFFG
MSMEG_2795|M.smegmatis_MC2_155 ----------------------------GKSRSLLRNPLAWT--VTLFFG
MMAR_0750|M.marinum_M --------------------------TGKKIGPIWRSPISWG--LTFMFS
MUL_1382|M.ulcerans_Agy99 --------------------------TGKKIGPIWRSPISWG--LTFMFS
MAB_2273|M.abscessus_ATCC_1997 --------------------------DSAAVGQVWRSPLAWG--MAGMFG
TH_2968|M.thermoresistible__bu PSTLGAAAASVVILVGWWCWEQRAAHPLVSTRMLSRRPMLLTNLATIFVG
MAV_1539|M.avium_104 -------------------------AALRNLAGHLRNPVLAKLFAVGFVL
Rv3021c|M.tuberculosis_H37Rv -------------------------------------GMIDMFFATVGFA
: . .
Mflv_0017|M.gilvum_PYR-GCK SQAFLAYIMMGWLPQVFIDNGIDKVQAGLLVA--VASLVGVPLSLVITPL
Mvan_0951|M.vanbaalenii_PYR-1 SQAFMAYIVMGWLPQVLVDNGVDQVQAGLLVG--LMSLIGVPISLLIAPM
MSMEG_2795|M.smegmatis_MC2_155 CQAFLAYIVMGWLPEVFIDSGVGKTQAGLLVG--LVSLLAVPISLVVAPL
MMAR_0750|M.marinum_M MTSLITYAMFAWLPVIVTSAGGSEALGGAMVA--TFSGVGFLATLVTPRL
MUL_1382|M.ulcerans_Agy99 MTSLITYAMFAWLPVIVTSAGGSEALGGAMVA--TFSGVGFLATLVTPRL
MAB_2273|M.abscessus_ATCC_1997 MTSLVTYSMFTWIPAILASAGGSAKLGGVMVA--LFSAVGFVGTLAIPPL
TH_2968|M.thermoresistible__bu MGLYFAFLGITLFVQVPRDQAGFGFSATVLQASVVYLLPGACTGFVVALV
MAV_1539|M.avium_104 MGGFVTVYNYLGYRLAARPFG----LAPSVVG---LLFLLYLVGTGTSVV
Rv3021c|M.tuberculosis_H37Rv LGVFVLVPLLEFAVVLELAILSIGWIISNIFG-------------AIPVL
. : . . :
Mflv_0017|M.gilvum_PYR-GCK AARSASQSGWIVGVGSFGFLGTVGLMVAPTAQPLLWSVLLGTGLSGFSLA
Mvan_0951|M.vanbaalenii_PYR-1 AARRPSQSGWIVAVGMFGFAGAIGLMVAPAAQPLLWSVLIGIGMSAFSMA
MSMEG_2795|M.smegmatis_MC2_155 AARQSGQTGWIVGLGVVGFAGMVGLLVDPGAAPLLWSVLVGLGMSVFSLA
MMAR_0750|M.marinum_M CARAANPFPIVAASALCFLVGFAGLLWAPLTAPIVWAIFLGLGPSTFPAA
MUL_1382|M.ulcerans_Agy99 CARAANPFPIVAASALCFLVGFAGLLWAPLTAPIVWAIFLGLGPSTFPAA
MAB_2273|M.abscessus_ATCC_1997 AARMRNPFPLVVACLVCFLIGFAGLLWLPMHGTAVWVVALGFGPSTFPLG
TH_2968|M.thermoresistible__bu SGRFIDRYGARPVLMVGALAGIGGFVFIAVAHTHTWQVIAAAVLTNAYIS
MAV_1539|M.avium_104 AGRLADRRGRPLVLGAALPIAVAGLLLTVPPSLAAIVAGVGVFTGGFFAA
Rv3021c|M.tuberculosis_H37Rv GGPLLGALAAAVVPGVAGLAGVAGLAALPAVGAAAGAPAALVGSVAPVSG
. . . *: .
Mflv_0017|M.gilvum_PYR-GCK LALLGLRARTP-EDTAALSGMAQGFGYLLAGTGPFLFGLLHDVTHGWTAP
Mvan_0951|M.vanbaalenii_PYR-1 LAVLGLRARTA-ADTAQLSGMVQGFGYLIAGAGPFLFGLLHDVSHGWTVP
MSMEG_2795|M.smegmatis_MC2_155 LTVIALRARTA-DDTAQLSGMAQGFGYLLAGFGPFLFGLLHDVTGGWTAP
MMAR_0750|M.marinum_M ITLINLRSRTE-SGSAALSGFTQGMGYLLASPGPLIFGILYNATGRWELS
MUL_1382|M.ulcerans_Agy99 ITLINLRSRTE-SGSAALSGFTQGMGYLLASPGPLIFGILYNATGRWELS
MAB_2273|M.abscessus_ATCC_1997 LTLVNLRTRTP-AGSAALSGFTQGVGYAVACLGPLLFGVLHDVSGGWYAP
TH_2968|M.thermoresistible__bu LGYGALPALVVGEAPPGATGIATGMNAIARTIGSSVAAALVAVAVAGSTT
MAV_1539|M.avium_104 HTVASGWVGAVAQRDRAEASALYLFSYYLGGSVAGAFGGVLYGVGGWSAT
Rv3021c|M.tuberculosis_H37Rv GVVSPQARLVSAVEPAPASTSVSVLASDRGAGALGFVGTAGKESVGQPAG
. : . .
Mflv_0017|M.gilvum_PYR-GCK WVLFLAVFCVQTVTGALAGRNRYV--------------------------
Mvan_0951|M.vanbaalenii_PYR-1 WMMFLAVYAVQIVAGALAGRARYV--------------------------
MSMEG_2795|M.smegmatis_MC2_155 WALVLAVYLVQMGAGALAGRNRYV--------------------------
MMAR_0750|M.marinum_M FGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSGSDAVEDVVEGERLQE
MUL_1382|M.ulcerans_Agy99 FGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSGSDAVEDVVEGERLQE
MAB_2273|M.abscessus_ATCC_1997 FGLLLVAITVLGVGAFQACKPRTLEDTWN----RGSGAVVSS--------
TH_2968|M.thermoresistible__bu AAPSEAGFTAIFAGGAVTALFAMLLIGLSRTGRPAFETVEARQESRAMNH
MAV_1539|M.avium_104 VCFVVVLLMAGAALVALLVRDNGFRIGRRVVAGVASVK------------
Rv3021c|M.tuberculosis_H37Rv LTVLADEFGDGAPVPMLPGSWGPDLVGVAGDGGLVSV-------------
Mflv_0017|M.gilvum_PYR-GCK ------
Mvan_0951|M.vanbaalenii_PYR-1 ------
MSMEG_2795|M.smegmatis_MC2_155 ------
MMAR_0750|M.marinum_M CSTSCA
MUL_1382|M.ulcerans_Agy99 CSTSCA
MAB_2273|M.abscessus_ATCC_1997 ------
TH_2968|M.thermoresistible__bu EWG---
MAV_1539|M.avium_104 ------
Rv3021c|M.tuberculosis_H37Rv ------