For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVR ALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAAR NPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2694c | - | - | 100% (250) | hypothetical protein Mb2694c |
| M. bovis AF2122 / 97 | Mb1412c | - | 5e-30 | 39.09% (197) | putative transferase |
| M. bovis AF2122 / 97 | Mb0575c | - | 9e-26 | 40.41% (146) | benzoquinone methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4471 | - | 8e-27 | 36.02% (186) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv2675c | - | 1e-148 | 100.00% (250) | hypothetical protein Rv2675c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0240 | - | 3e-45 | 45.91% (220) | hypothetical protein MAB_0240 |
| M. marinum M | MMAR_2041 | - | 1e-115 | 77.60% (250) | methyltransferase |
| M. avium 104 | MAV_3570 | - | 1e-119 | 78.80% (250) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. smegmatis MC2 155 | MSMEG_3041 | - | 7e-30 | 40.43% (188) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. thermoresistible (build 8) | TH_1722 | - | 2e-24 | 33.17% (199) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3309 | - | 1e-114 | 77.20% (250) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1888 | - | 1e-27 | 36.82% (201) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2694c|M.bovis_AF2122/97 ----MTAQFDPADPTRFEEMYRDDRVAHGLP--AATPWDIGGPQPVVQQL
Rv2675c|M.tuberculosis_H37Rv ----MTAQFDPADPTRFEEMYRDDRVAHGLP--AATPWDIGGPQPVVQQL
MAV_3570|M.avium_104 ----MTASFDPADPARFEEMYRDQRTSHGLP--AATPWDIGGPQPVVRQL
MMAR_2041|M.marinum_M ----MTAP-DPTDPTRFEEMYRDQRVAHGLP--AATPWDIGGPQPVVEQL
MUL_3309|M.ulcerans_Agy99 ----MTAP-DPTDPTRFEEMYRDQRVAHGLP--AATPWDIGGPQPVVEQL
MAB_0240|M.abscessus_ATCC_1997 --------MRPDGPGFFAELMYAVN---------AAPWDIGGPQPVIRQL
Mflv_4471|M.gilvum_PYR-GCK -----MDMDQTPTLSRFDDFYKDED--------KTPPWVIGEPQPAVVDI
Mvan_1888|M.vanbaalenii_PYR-1 -------MDLTPRLSRFDEFYKN----------QTPPWVIGEPQQAIVEL
MSMEG_3041|M.smegmatis_MC2_155 ------MTGPTGSEFDFDALYRGESPAEGVPPITSVPWDTKAPKENVVAW
TH_1722|M.thermoresistible__bu MATEDPGTGDPTDTIDWDSVYRQEAPGFDGP----PPWNIGEPQPELAAL
. : . ** *: :
Mb2694c|M.bovis_AF2122/97 VALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARDNARK
Rv2675c|M.tuberculosis_H37Rv VALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARDNARK
MAV_3570|M.avium_104 VALGAVKGEVLDPGTGPGHHAIYYASQGFSATGIDGSAAAIERARANART
MMAR_2041|M.marinum_M VALGAVKGEVLDPGTGPGHHAIYYASKGYSATGIDGSATAIERARDNAAK
MUL_3309|M.ulcerans_Agy99 VALGAVKGEVLDPGTGPGHHAIYYASKGYSATGIDGSATAIERARDNAAK
MAB_0240|M.abscessus_ATCC_1997 VALGAVRGEVLDPGCGTGWHAIEYARAGCSVTGVDLAPTAIARARNNTRT
Mflv_4471|M.gilvum_PYR-GCK ERAGLITGRVLDVGCGTGERTILLTAAGYDVLGVDGAPSAVEQARHNAKT
Mvan_1888|M.vanbaalenii_PYR-1 EQAGLIGGRVLDVGCGTGEHTILLARAGYDVLGIDGAPTAVEQARRNAEA
MSMEG_3041|M.smegmatis_MC2_155 EQAGLVHGHVLDIGCGLGDNAIYLAQQGYRVTALDISPTALITAERRAAD
TH_1722|M.thermoresistible__bu HRAGAFRSDVLDAGCGHAEISMALAADGYTVVGIDLSPTAIAAANRTAQE
* . . *** * * . :: : * . .:* : :*: *. :
Mb2694c|M.bovis_AF2122/97 AGVSVN-FQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALR
Rv2675c|M.tuberculosis_H37Rv AGVSVN-FQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALR
MAV_3570|M.avium_104 AGVSVN-FELADATKLDGFDGRFDTVVDCAFYHVFATEPELRSSYARALH
MMAR_2041|M.marinum_M AGVSVN-FQVADATRLEGLDNRFDTVVDCAFYHTFGTAPELQRSYVRALW
MUL_3309|M.ulcerans_Agy99 AGVSVN-FQVADATRLEGLDNRFDTVVDCAFYHTFGTAPELQRSYVQALW
MAB_0240|M.abscessus_ATCC_1997 AGVEAQ-FVLGDATTLD-YEARFDTVVDSKLLDNLDSA-EARGRYLRSLY
Mflv_4471|M.gilvum_PYR-GCK RVVDAR-FDVADALDLG-DEPAYDTIIDSALFHIFDDA--DREKYVRSLG
Mvan_1888|M.vanbaalenii_PYR-1 QGVDAR-FELADALHLG-PDPTYDTIVDSALFHIFDDA--DRATYVRSLH
MSMEG_3041|M.smegmatis_MC2_155 AGVDVT-FAVADATRLDGYDDVFDTVVDSGMFHCLSDD--AKGSYAAAVH
TH_1722|M.thermoresistible__bu RGLATASFVQGDITDFGGYDGRFNTIIDSTLFHSIPVQ--ARDGYLRSIH
: . * .* : : ::*::*. : . : : * ::
Mb2694c|M.bovis_AF2122/97 RASKPGARLYMFEFG----EHNVNGFSMPRSLSEDDFRQVLPVGGWEITY
Rv2675c|M.tuberculosis_H37Rv RASKPGARLYMFEFG----EHNVNGFSMPRSLSEDDFRQVLPVGGWEITY
MAV_3570|M.avium_104 RATKPGARLYMFEFG----EHDVNGFKMMRSLSENDFRDVLPAAGWEISY
MMAR_2041|M.marinum_M RATKPGARLYMYEFG----AHQVNGLTAIRSLPEENFREMLPLGGWEITY
MUL_3309|M.ulcerans_Agy99 RATKPGARLYMYEFG----AHQVNGLTAIRSLPEENFREMLPLGGWEITY
MAB_0240|M.abscessus_ATCC_1997 RAMKPQGRLFLYGFS----DGHVNGFHN-HELDGIDYEMALTAAGFTITY
Mflv_4471|M.gilvum_PYR-GCK RATAPGSVVHLLALSD---TGRGFG----PEVSEETIRAAFADPGWDIEA
Mvan_1888|M.vanbaalenii_PYR-1 AATRPGSVVHLLALSD---SGRGFG----PEVSEHTIRAAFG-AGWEVEA
MSMEG_3041|M.smegmatis_MC2_155 RATRAGATLLLGAFSD---ANLQHDNWQAAWVSEDTLRSSLDDGGWDITS
TH_1722|M.thermoresistible__bu RAAAPGARYFALVFAKGAFPEEMEQGPGPNPVDEDELREAVS-KYWEIDE
* . . :. : . . : :
Mb2694c|M.bovis_AF2122/97 LGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHA
Rv2675c|M.tuberculosis_H37Rv LGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHA
MAV_3570|M.avium_104 LGPTTYQVNLSAETIQMMAARNPDMADEAAKLLERFRAMEPWLQAGRVHA
MMAR_2041|M.marinum_M LGPTTYRTTVSMETLETMAARNPEVADQVGPLVERFKTIQPWLTDGIAHV
MUL_3309|M.ulcerans_Agy99 LGPTTYRTTVSMETLETMAARNPEVADQVGPLVERFKTIQPWLTDGIAHV
MAB_0240|M.abscessus_ATCC_1997 LGETTYR--LSIPSYRRICTDCP---DQVP-------------PDGQIHI
Mflv_4471|M.gilvum_PYR-GCK LTTTYYRGVITAPHADAMGLDVG----------------------TVVDE
Mvan_1888|M.vanbaalenii_PYR-1 LTETTYRGVVIDAHTEALNLPAG----------------------TVVDE
MSMEG_3041|M.smegmatis_MC2_155 LTTETIR-VPGAALAGSGDEGGA----------------------DEFDA
TH_1722|M.thermoresistible__bu IRPAFIHANMPPDVPGVESFDTD--------------------EKGRTKL
: : .
Mb2694c|M.bovis_AF2122/97 PFWEVHATRVD----
Rv2675c|M.tuberculosis_H37Rv PFWEVHATRVD----
MAV_3570|M.avium_104 PFWEVHATRVD----
MMAR_2041|M.marinum_M PFWEVHATRLD----
MUL_3309|M.ulcerans_Agy99 PFWEVHATRPD----
MAB_0240|M.abscessus_ATCC_1997 PMIEIHAVRNGLWQA
Mflv_4471|M.gilvum_PYR-GCK PAWLARIRRL-----
Mvan_1888|M.vanbaalenii_PYR-1 PAWSARIRRL-----
MSMEG_3041|M.smegmatis_MC2_155 AFFLVQAQRR-----
TH_1722|M.thermoresistible__bu PAFLLSAHKA-----
. :