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M. thermoresistible (build 8) TH_1722 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 3309263 - 3309964
length: 234

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1722-100% (234)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_3824-9e-5750.00% (232) PUTATIVE thiopurine S-methyltransferase (tpmt) superfamily
M. thermoresistible (build 8)TH_3761-3e-1132.81% (128) PUTATIVE methyltransferase type 12

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3725-3e-8667.67% (232) hypothetical protein Mb3725
M. gilvum PYR-GCKMflv_1324-3e-7965.02% (223) methyltransferase type 11
M. tuberculosis H37RvRv3699-3e-8667.67% (232) hypothetical protein Rv3699
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0961c-3e-7664.25% (221) hypothetical protein MAB_0961c
M. marinum MMMAR_5210-1e-8266.52% (230) hypothetical protein MMAR_5210
M. avium 104MAV_0404-6e-8671.17% (222) thiopurine S-methyltransferase (tpmt) superfamily protein
M. smegmatis MC2 155MSMEG_6235-1e-9072.73% (220) thiopurine S-methyltransferase (tpmt) superfamily protein
M. ulcerans Agy99MUL_0662-1e-5757.00% (207) methyltransferase
M. vanbaalenii PYR-1Mvan_5471-1e-8066.52% (224) methyltransferase type 11

CLUSTAL 2.0.9 multiple sequence alignment


TH_1722|M.thermoresistible__bu      MATEDPGTGDPTDTIDWDSVYRQEAPGFDG--PPPWNIGEPQPELAALHR
MSMEG_6235|M.smegmatis_MC2_155      MGVMT------SHVLDWDGAYRGDT-GFQG--PPPWNIGEPQPELAALHR
Mb3725|M.bovis_AF2122/97            ---MT------DEVMDWDSAYREQG-AFEG--PPPWNIGEPQPELATLIA
Rv3699|M.tuberculosis_H37Rv         ---MT------DEVMDWDSAYREQG-AFEG--PPPWNIGEPQPELATLIA
MMAR_5210|M.marinum_M               ---MT------SPVMDWDDAYQQQG-AFEG--PPPWNIGEPQPELAALIA
MAV_0404|M.avium_104                --MSS------DQVMDWDSAYREQA-HFEG--PPPWNIGEPQPELAALIE
Mflv_1324|M.gilvum_PYR-GCK          ---MA-------EVMDWDSAYRGEG-EFEG--EPPWNIGEPQPELAALWR
Mvan_5471|M.vanbaalenii_PYR-1       MAHMT-------DVMDWDSAYRGEG-DFEG--EPPWNIGEPQPELAALWR
MAB_0961c|M.abscessus_ATCC_199      ---MTS-----NELPDWDATYQGKGELFQG--EPPWNIGEPQPELAALID
MUL_0662|M.ulcerans_Agy99           ---MT-----ESLDLQFATAYRGESAEFGAGIRPPWSLGEPQPELATLIE
                                                   ::  .*: .   * .   ***.:********:*  

TH_1722|M.thermoresistible__bu      AGAFRSDVLDAGCGHAEISMALAADGYTVVGIDLSPTAIAAANRTAQERG
MSMEG_6235|M.smegmatis_MC2_155      AGRFRSDVLDAGCGHAELSLALAADGYTVVGMDLSPSAIAAANRAAQERN
Mb3725|M.bovis_AF2122/97            AGKVRSDVLDAGCGYAELSLALAADGYTVVGIDLTPTAVAAATKAAEERG
Rv3699|M.tuberculosis_H37Rv         AGKVRSDVLDAGCGYAELSLALAADGYTVVGIDLTPTAVAAATKAAEERG
MMAR_5210|M.marinum_M               AGKIHSDVLDAGCGYAELSLALAAEGYTVVGIDITPTAIAAATKAAAERG
MAV_0404|M.avium_104                QGKFRSDVLDAGCGCAELSLALAARGYTVVGIDLTPTAVAAATRAAAERG
Mflv_1324|M.gilvum_PYR-GCK          DGRFRSEVLDAGCGHAELSLALAADGYTVTGVDISPTAMAAASAAAAERG
Mvan_5471|M.vanbaalenii_PYR-1       DGKFRSEVLDAGCGHAELSLALAADGYTVTGVDLSPTAVAAATAASAERG
MAB_0961c|M.abscessus_ATCC_199      AGKFHGTVLDVGCGHAETSLRLAALGHTTVGLDLSPTAIEAARAAAAERG
MUL_0662|M.ulcerans_Agy99           QGKVHGEVLDAGCGEAALAMALAGRGHPVVGLDISPTAVELAGREAARPG
                                     * .:. ***.*** *  :: **. *:...*:*::*:*:  *   : . .

TH_1722|M.thermoresistible__bu      LAT-ASFVQGDITDFGGY----DGRFNTIIDSTLFHSIPVQARDGYLRSI
MSMEG_6235|M.smegmatis_MC2_155      LAT-ASFVQGDITSFTGY----DGRFSTVIDSTLFHSLPVEGREGYLQSI
Mb3725|M.bovis_AF2122/97            LTT-ASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRYLSSV
Rv3699|M.tuberculosis_H37Rv         LTT-ASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRYLSSV
MMAR_5210|M.marinum_M               LGN-TSFMQADITDFNAYPAGSAGRFATVIDSTLFHSLPVSGRDDYLKSV
MAV_0404|M.avium_104                LTT-ASFVQADITSFTGY----DGRFATVVDSTLFHSLPVEGRDGYLRSI
Mflv_1324|M.gilvum_PYR-GCK          LSEKASFVAADITALSGF----DGRFSTVVDSTLFHSLPVESRAGYLESV
Mvan_5471|M.vanbaalenii_PYR-1       LSERTSFVAADITTLTGF----DGRFATVVDSTLFHSLPVESRDGYLQSV
MAB_0961c|M.abscessus_ATCC_199      LTN-ATFEVADITDFSGY----DGRFNTIVDSTLFHSIPVEAREAYLQSI
MUL_0662|M.ulcerans_Agy99           LTN-ASFAVADITDFASYPPESAGRFNTIMDSTLFHSMPVELREGCQRSI
                                    *   ::*  .*** : .:     *** *::*******:**. *     *:

TH_1722|M.thermoresistible__bu      HRAAAPGARYFALVFAKGAFPEEMEQGPGPNPVDEDELREAVSKYWEIDE
MSMEG_6235|M.smegmatis_MC2_155      HRASAPGARYFVLVFAKGAFPADLEVK--PNEVTEEELRTTVGKYWVVDD
Mb3725|M.bovis_AF2122/97            HRAAAPGASYYVLVFAKGAFPAELEVK--PNEVDEDELRAAVSKYWKIDE
Rv3699|M.tuberculosis_H37Rv         HRAAAPGASYYVLVFAKGAFPAELEVK--PNEVDEDELRAAVSKYWKIDE
MMAR_5210|M.marinum_M               HRAAAPGASYFVLVFAKGAFPAALETK--PNEVDEDELRAAVGKYWEIDE
MAV_0404|M.avium_104                HRAAAAGASLFILVFAKGAFPAEMQPK--PNEVDEDELRAAVGKYWVIDE
Mflv_1324|M.gilvum_PYR-GCK          HRAARPGAGFFVLVFAKGAFPADTEQG--PNEVSEIELREAVSPYWTIDD
Mvan_5471|M.vanbaalenii_PYR-1       HRAAAPGAGYFVLVFAKGAFPAEMEGG--PNEVTELELREAVSRYWIIDD
MAB_0961c|M.abscessus_ATCC_199      SRAAAPDASYFVLVFAVGAFPPGIG----PNAVTEDELRAAVEPYWAIDE
MUL_0662|M.ulcerans_Agy99           VRAAAPGASYFVLVFDKAALSGDGPIN----GVTEEELRDAVSKHWVIDE
                                     **: ..*  : ***  .*:.           * * *** :*  :* :*:

TH_1722|M.thermoresistible__bu      IRPAFIHAN------MPPDVP-GVESFDT-----DEKGRTK------LPA
MSMEG_6235|M.smegmatis_MC2_155      IRPAFIHANAV----VFPDAP-ELPPHGY-----DDKGRIM------FPA
Mb3725|M.bovis_AF2122/97            IRPAFIHVNPVTIPPQLAGAPVEFPPYDH-----DEKGRVK------FPA
Rv3699|M.tuberculosis_H37Rv         IRPAFIHVNPVTIPPQLAGAPVEFPPYDH-----DEKGRVK------FPA
MMAR_5210|M.marinum_M               IRPAFIHANVPVIPPLPAGSPIEFPPHQR-----DEKGRMK------FPA
MAV_0404|M.avium_104                IRPSFIVSN----VPQIADAPFEFPAHER-----DERGRMK------MPA
Mflv_1324|M.gilvum_PYR-GCK          IRPALIHTN----VPKLPGMP-PPPLDML-----DDRGHLR------MQA
Mvan_5471|M.vanbaalenii_PYR-1       IRPALIDTN----VPKLPGMP-PPPLDML-----DDRGRLR------MQA
MAB_0961c|M.abscessus_ATCC_199      LSSAYIHSN---IPEVIPGANFEMPVFHK-----DEKGRNK------QPA
MUL_0662|M.ulcerans_Agy99           IRPARIHAN---LPPEVPGCPPSTLATNPRAASPSVRGCSQPIWADGTPH
                                    : .: *  *        ..               . :*            

TH_1722|M.thermoresistible__bu      FLLSAHKA-
MSMEG_6235|M.smegmatis_MC2_155      FLLEAHRD-
Mb3725|M.bovis_AF2122/97            YLLTAHKAG
Rv3699|M.tuberculosis_H37Rv         YLLTAHKAG
MMAR_5210|M.marinum_M               YLLTAHKA-
MAV_0404|M.avium_104                YLLTAHKAQ
Mflv_1324|M.gilvum_PYR-GCK          FLLSAHKEP
Mvan_5471|M.vanbaalenii_PYR-1       FLLQAHKES
MAB_0961c|M.abscessus_ATCC_199      FLLQAHKR-
MUL_0662|M.ulcerans_Agy99           AVYSPANEG
                                     :  . .