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M. bovis AF2122 / 97 Mb2537 (-)

annotation: putative short-chain type dehydrogenase/reductase
coordinates: 2791475 - 2792281
length: 268

MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVTVDVRPADLAD
PQERSKLADELAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGIL
ISGSAAGNSPIPYNATYAATKAFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEASLVEKLVPDF
LWISTEHTARVSLNALERNKMRVVPGLTSKAMSVASQYAPRAIVAPIVGAFYKRLGGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2537--100% (268)putative short-chain type dehydrogenase/reductase
M. bovis AF2122 / 97Mb1571-3e-5243.07% (267) ketoacyl reductase
M. bovis AF2122 / 97Mb0788c-2e-2333.94% (221) short chain dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2545-1e-11376.40% (267) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv2509-1e-147100.00% (268) short-chain type dehydrogenase/reductase
M. leprae Br4923MLBr_00429-1e-13188.76% (267) putative oxidoreductase
M. abscessus ATCC 19977MAB_1537c-1e-11478.20% (266) putative short chain dehydrogenase/reductase
M. marinum MMMAR_3856-1e-13691.76% (267) short-chain type dehydrogenase/reductase
M. avium 104MAV_1666-1e-13187.27% (267) short-chain dehydrogenase
M. smegmatis MC2 155MSMEG_4722-1e-11779.03% (267) short-chain dehydrogenase
M. thermoresistible (build 8)TH_1383-1e-11879.40% (267) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. ulcerans Agy99MUL_3788-1e-13591.01% (267) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_4098-1e-11476.78% (267) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb2537|M.bovis_AF2122/97            MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELA
Rv2509|M.tuberculosis_H37Rv         MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELA
MLBr_00429|M.leprae_Br4923          MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLA
MMAR_3856|M.marinum_M               MPIPAPSPDARAVVTGASQNIGEALATELAARGHNLIVTARRESLLNELA
MUL_3788|M.ulcerans_Agy99           MPIPAPSPDARAVVTGASQNIGEALATELAARGHNLIVTARRESLLNELA
MAV_1666|M.avium_104                MPIPAPSPEARAVVTGASQNIGEALATELAARGHHLIVTARREDLLKDLA
MAB_1537c|M.abscessus_ATCC_199      MPIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIITARRGEILNDLA
Mflv_2545|M.gilvum_PYR-GCK          MPVPAPSADARAVVTGASQNIGEALAVELARRGHHLIITARREEVLNALA
Mvan_4098|M.vanbaalenii_PYR-1       MPVPAPSEDARAVVTGASQNIGEALAVELAERGHHLIITARREEVLNALA
MSMEG_4722|M.smegmatis_MC2_155      MPVPAPSPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTSLA
TH_1383|M.thermoresistible__bu      MPVPEPTPDARAVITGASQNIGAALATELAARGHNLIVTARRAEVLTELA
                                    **:* *: :****:*****.** *** *** :** **: *** .:*  **

Mb2537|M.bovis_AF2122/97            ARLADKYRVTVDVRPADLADPQERSKLADELAARPISILCANAGTATFGP
Rv2509|M.tuberculosis_H37Rv         ARLADKYRVTVDVRPADLADPQERSKLADELAARPISILCANAGTATFGP
MLBr_00429|M.leprae_Br4923          ARLADKYRVAVEVRPADLTDPSERVKLADELTVRPISILCANAGTATFGP
MMAR_3856|M.marinum_M               ARLTDKYRVTVEVRPADLADPQERTKLTDELAARPISILCANAGTATFGP
MUL_3788|M.ulcerans_Agy99           ARLTDKYRVSVEVRPADLADPQERTKLTDELAARPISILCANAGTATFGP
MAV_1666|M.avium_104                ARLTEKYRVTVEVRPADLADAGERATLCDELAARPISVLCANAGTATFGP
MAB_1537c|M.abscessus_ATCC_199      NALSEKTGVIVEVRAVDLADPGARDALCTELSERNISILCNNAGTATFGP
Mflv_2545|M.gilvum_PYR-GCK          DRLRSEFGVTVEVRAVDLADPAARDVFCEELATRTISILCANAGTATFGA
Mvan_4098|M.vanbaalenii_PYR-1       ERLRQKYGVTVEVRAVDLADPVSRGAFCDELAGRNISILCANAGTATFGA
MSMEG_4722|M.smegmatis_MC2_155      QRLTERYGVTVEVRAVDLTDPAARATLCDELAEREISILCANAGTATFGA
TH_1383|M.thermoresistible__bu      DRLTDRHGVTVEVRPLDLADPEQRGTLCAELAEREISILCANAGVATFGP
                                      * ..  * *:**. **:*.  *  :  **: * **:** ***.****.

Mb2537|M.bovis_AF2122/97            IASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSP
Rv2509|M.tuberculosis_H37Rv         IASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSP
MLBr_00429|M.leprae_Br4923          VSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSP
MMAR_3856|M.marinum_M               VASLDPAGEKAQVQLNAVAVHDLTLAVLPGMIERRAGGILISGSAAGNSP
MUL_3788|M.ulcerans_Agy99           VASLDPAGEKAQVQLNAVAVHDLTLAVLPGMIERRAGGILISGSAAGNSP
MAV_1666|M.avium_104                VATLDPAGEKAQVQLNVLGVHDLTLAVLPGMVERRAGGILISGSAAGNSP
MAB_1537c|M.abscessus_ATCC_199      IRGLDPAGERKQVQLNAVAVHDLTLAVLPGMLARGAGGILISGSAAGNSP
Mflv_2545|M.gilvum_PYR-GCK          VASLDPADERKQVQLNVLGVHDLVLAVLPGMVARRAGGILISGSAAGNSP
Mvan_4098|M.vanbaalenii_PYR-1       VHALDPAEERKQVQLNVLGVHDLVLAVLPGMVQRRAGGILISGSAAGNSP
MSMEG_4722|M.smegmatis_MC2_155      VKDLDPAGEKAQVQLNVLGVHDLVLAVLPGMVARRAGGILISGSAAGNSP
TH_1383|M.thermoresistible__bu      VHKLDPAEEKAQVQLNVLGVHDLVLAVLPGMVQRRAGGILISGSAAGNSP
                                    :  ** * *: *****.:.****.*******: * ***************

Mb2537|M.bovis_AF2122/97            IPYNATYAATKAFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEA
Rv2509|M.tuberculosis_H37Rv         IPYNATYAATKAFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEA
MLBr_00429|M.leprae_Br4923          IPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDHDEA
MMAR_3856|M.marinum_M               IPYNATYAATKAFANTFSESLRGELRGSGVHVTLLAPGPVRTDLPDASEA
MUL_3788|M.ulcerans_Agy99           IPYNATYAATKAFANTFSESLRGELRGSGVHVTLLAPGPVRTDLPDASEA
MAV_1666|M.avium_104                IPYNATYAATKAFVNTFSESLRGELRGSGVHVTLLAPGPVRTDLPDDAEA
MAB_1537c|M.abscessus_ATCC_199      IPNNATYAATKAFANTFSESLRGELKGTGVHVTLLAPGPVRTVEPDPAEA
Mflv_2545|M.gilvum_PYR-GCK          IPNNATYAATKAFANTFGESLRGEVKSTGVHVTVLAPGPVRTELPDPDEQ
Mvan_4098|M.vanbaalenii_PYR-1       IPNNATYAATKAFANTFGESLRGEVKSAGVHVTVLAPGPVRTELPDPDEQ
MSMEG_4722|M.smegmatis_MC2_155      IPNNATYAASKAFANTFSESLRGELTGVGVHVTLLAPGPVRTELPDPSEQ
TH_1383|M.thermoresistible__bu      IPNNATYAATKAFANTFSESLRGELKDLGVHVTLLAPGPVRSDLPDPSEA
                                    ** ******:***.***.******: . *****:*******:  **  * 

Mb2537|M.bovis_AF2122/97            SLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSKAMSVASQYAP
Rv2509|M.tuberculosis_H37Rv         SLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSKAMSVASQYAP
MLBr_00429|M.leprae_Br4923          SLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKAMSVASRYAP
MMAR_3856|M.marinum_M               SLVERLVPDFLWISTEHTAQVSLDALARNKMRVVPGLTSKAMSVASQYAP
MUL_3788|M.ulcerans_Agy99           SLVERLVPDFLWISTEHTAQVSLDALARNKMRVVAGLTSKAMSVASQYAP
MAV_1666|M.avium_104                SIVERLVPDFLWISTEHTARVSLDALGRNKMRVVPGLTSKAMSVASGYAP
MAB_1537c|M.abscessus_ATCC_199      SIVDKVVPDFLWINGEYTARVSLNALERNKMRVVPGITSKAMSVAAGYAP
Mflv_2545|M.gilvum_PYR-GCK          SLVERLIPDFLWIDTEYTAKVSLDGLDRNKMRVVPGVTSKAMSAASGYAP
Mvan_4098|M.vanbaalenii_PYR-1       SLVERLIPDFLWIDTEYTAKVSLDGLDRNKMRVVPGITSKAMSAASGYAP
MSMEG_4722|M.smegmatis_MC2_155      SLVERLIPDFLWIDTEYTAKLSLDGLEHNKMRVVPGVTSKAMSVASGYAP
TH_1383|M.thermoresistible__bu      SLVDRLVPDFLWISTEHTAKLSLDGLAANKMRVVPGLTSKAMSVASGYAP
                                    *:*::::******. *:**::**:.*  ******.*:******.*: ***

Mb2537|M.bovis_AF2122/97            RAIVAPIVGAFYKRLGGS
Rv2509|M.tuberculosis_H37Rv         RAIVAPIVGAFYKRLGGS
MLBr_00429|M.leprae_Br4923          RAIVASIVGNFYKKLGGG
MMAR_3856|M.marinum_M               RAIVAPIVGGFYKKLGGG
MUL_3788|M.ulcerans_Agy99           RAIVAPIVGGFYKKLGGG
MAV_1666|M.avium_104                RAIVAPIVGSFYKKLGGG
MAB_1537c|M.abscessus_ATCC_199      RAVVAPIVGSFYKKLGD-
Mflv_2545|M.gilvum_PYR-GCK          RAIVAPIVGAVYKKLGGD
Mvan_4098|M.vanbaalenii_PYR-1       RAIVAPIVGAVYKKLGGD
MSMEG_4722|M.smegmatis_MC2_155      RAIVTPIVGAVYKKLGGG
TH_1383|M.thermoresistible__bu      RAIVAPIVGAFYKKLGGG
                                    **:*:.*** .**:**.