For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0476 (-)

annotation: major facilitator superfamily protein MFS_1
coordinates: 1012753 - 1013925
length: 391

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0476--100% (391)major facilitator superfamily protein MFS_1
M. thermoresistible (build 8)TH_2729-1e-1122.30% (453) PUTATIVE putative drug resistance transporter, EmrB/QacA
M. thermoresistible (build 8)TH_3965-3e-1127.53% (178) PUTATIVE drug transporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3755-8e-1726.27% (415) hypothetical protein Mb3755
M. gilvum PYR-GCKMflv_1450-9e-4729.82% (379) major facilitator transporter
M. tuberculosis H37RvRv3728-1e-1626.27% (415) hypothetical protein Rv3728
M. leprae Br4923MLBr_00556-2e-0822.62% (420) putative integral membrane drug transport protein
M. abscessus ATCC 19977MAB_1299c-1e-13462.30% (382) multidrug ABC transporter
M. marinum MMMAR_0729-8e-1624.09% (440) transmembrane transport protein
M. avium 104MAV_0138-5e-2830.34% (356) transporter, major facilitator family protein
M. smegmatis MC2 155MSMEG_5167-1e-15772.16% (388) major facilitator superfamily protein MFS_1
M. ulcerans Agy99MUL_3590-2e-1624.32% (440) transmembrane transport protein
M. vanbaalenii PYR-1Mvan_5329-1e-4630.34% (379) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


TH_0476|M.thermoresistible__bu      ---------------------------------VRR-FAFPLLAYAFA--
MSMEG_5167|M.smegmatis_MC2_155      ------------------------------MPHTRR-FSFALLAYAFA--
MAB_1299c|M.abscessus_ATCC_199      -----------------------------MIARLRRSAAFVLLAFSFS--
Mflv_1450|M.gilvum_PYR-GCK          -----------------------MVAIDRSIGETQR-WAYPLLLVLSG--
Mvan_5329|M.vanbaalenii_PYR-1       -----------------------MVAFDRSIPDTQR-WAYPLLLVLSG--
Mb3755|M.bovis_AF2122/97            MHTVATNNAAPVIAAGPVGPSRRRRRVHAPLTRRRQPSSSAVLLVAAFGA
Rv3728|M.tuberculosis_H37Rv         MHTVATNNAAPVIAAGPVGPSRRRRRVHAPLTRRRQPSSSAVLLVAAFGA
MMAR_0729|M.marinum_M               MHLSAP-------------------AERSALTSRRQPSATAVLLVASFGA
MUL_3590|M.ulcerans_Agy99           MHLSAP-------------------AERSALTSRRQPSATAVLLVASFGA
MLBr_00556|M.leprae_Br4923          ----------------------------MSTRAGRRVAISAGSLAVLLGA
MAV_0138|M.avium_104                -----------------MMSSNVRAARNRPGRTDPQPPTGAPLFVGVLGL
                                                                       :              

TH_0476|M.thermoresistible__bu      --AVMVGTTVPTPMYAVYAERLGFGVLTTTVVFAGYTAGVLFALVVFGRW
MSMEG_5167|M.smegmatis_MC2_155      --AIMVGTTLPTPMYALYAEHMNFAVLTTTVIYATYAGGVLFALLLFGRW
MAB_1299c|M.abscessus_ATCC_199      --AVMIGTTMPTPMYALYSQQMHFSVLTTTVVYATYAAGVLFALLMFGGW
Mflv_1450|M.gilvum_PYR-GCK          --VALGVSGLPAPLYGIYETNWHLSPLATTIVFAVYAVAALAAVLVSGRI
Mvan_5329|M.vanbaalenii_PYR-1       --VALGVSGLPAPLYGIYETNWHLSPLATTVVFAVYAVAALAAVLVSGRI
Mb3755|M.bovis_AF2122/97            FLAFLDSTIVNVAFPDIQRHFHS-DISDLSWMLNAYNIVFAAFLVAAGRL
Rv3728|M.tuberculosis_H37Rv         FLAFLDSTIVNVAFPDIQRHFHS-DISDLSWMLNAYNIVFAAFLVAAGRL
MMAR_0729|M.marinum_M               FLAFLDSTIVNIAFPDIQRSFPSYDISSLSWILNGYNIVFAAFLVASGRL
MUL_3590|M.ulcerans_Agy99           FLAFLDSTIVNIAFPHIQRSFPSYDISSLSWILNGYNIVFAAFLVASGRL
MLBr_00556|M.leprae_Br4923          LDTYVVVTIMRDIMHDVG--IPVNQMQRITWIVTMYLLGYIAAMPLLSRA
MAV_0138|M.avium_104                LLATGWVANHFVGLMPAISDRDHLATTTLDGIFGIYALGLLPGLLVGGRT
                                      .    :     :                 :   *       :   .  

TH_0476|M.thermoresistible__bu      SDALGRRPMLLAGVGCAIVSALVFLIA---GSVPQLIAARFVSGMSAGIF
MSMEG_5167|M.smegmatis_MC2_155      SDAIGRRPMLLAGVAAALISAGVFLMA---DSVPVLLIGRIFSGLSAGIF
MAB_1299c|M.abscessus_ATCC_199      SDVLGRRPLLLTGAGFAILSSVIFLFV---DSVPLLLVARIVSGLSAGFF
Mflv_1450|M.gilvum_PYR-GCK          SDVVGRKPVLLGALVALLIGLGVFLIA---DSMAMLLLARAIHGVAVGSI
Mvan_5329|M.vanbaalenii_PYR-1       SDVVGRKPVLVGALVALLIGLGVFLIA---DSMAMLLLARTIHGAAVGSI
Mb3755|M.bovis_AF2122/97            ADLMGRKRVFILGVALFTVASGLCAIA---ESVGELVAFRVLQGIGAAVL
Rv3728|M.tuberculosis_H37Rv         ADLMGRKRVFILGVALFTVASGLCAIA---ESVGELVAFRVLQGIGAAVL
MMAR_0729|M.marinum_M               ADVLGRKRMFVFGVVLFTIASGLCAVA---GDVEQLVGFRVLQGIGAAVL
MUL_3590|M.ulcerans_Agy99           ADVLGRKRMFVFGVVLFTIASGLCAVA---GDVEQLVGFRVLQGIGAAVL
MLBr_00556|M.leprae_Br4923          SDRFGRKLLLQVSLAGFAIGSVMTALAGQFGDFHMLIAGRTIQGVASGAL
MAV_0138|M.avium_104                SDALGRRPVALTGSAAALVGTVAMLLS---QHSPALFAGRLIVGLGVGLA
                                    :* .**: :   .     :.     .         *.  * . * . .  

TH_0476|M.thermoresistible__bu      TGTATAAVIEAAPERRRSRAAAVATVANIGGLGAGPLLAGILVQYAP-WP
MSMEG_5167|M.smegmatis_MC2_155      TGTATAAVIEAAPPAWRTRAAAVATVANIGGLGTGPLLAGLLVEYAP-RP
MAB_1299c|M.abscessus_ATCC_199      TGAATVAVIESAPETWRGRAAAVATVANTGGLGLGPLLAGVLVQYAP-WP
Mflv_1450|M.gilvum_PYR-GCK          VVAGAAALLDLRPDHG-VRVGQLSGVAFNIGMTIAIFGSALLAQYAP-HP
Mvan_5329|M.vanbaalenii_PYR-1       VVAGAAALLDLRPDHG-VRAGQLSGVSFNIGMTVAILGSALLAQYAP-HP
Mb3755|M.bovis_AF2122/97            VPASLGLVVEAFPAERRAHGVNLWGAAGAIAAGLGPPIGGALIEADG-WR
Rv3728|M.tuberculosis_H37Rv         VPASLGLVVEAFPAERRAHGVNLWGAAGAIAAGLGPPIGGALIEADG-WR
MMAR_0729|M.marinum_M               VPASLALVVEGFDASHRAHAVGLWGAAAAVASGLGPPVGGMLVEASS-WR
MUL_3590|M.ulcerans_Agy99           VPASLALVVEGFDASHRAHAVGLWGAAAAVASGLGPPVGGMLVEASS-WR
MLBr_00556|M.leprae_Br4923          LPITLALGADLWAQRNRAGVLGGIGAAQELGSVLGPLYGIFIVWLFSDWR
MAV_0138|M.avium_104                ISAGTAWASDLRGPAG----AATAGAVLTAGFAVGPFAGGVLAWAGP-SG
                                             :               .    .   .   .  :        

TH_0476|M.thermoresistible__bu      LHLTFWVHIVLMVLAAAAIAVA--PETSPR--------------------
MSMEG_5167|M.smegmatis_MC2_155      LHLSFVVHIVMAVLAGAAVFAV--PETSSR--------------------
MAB_1299c|M.abscessus_ATCC_199      THLAFVVHIGLVSIAVAALLFV--PETAPK--------------------
Mflv_1450|M.gilvum_PYR-GCK          LRTPYAVVAVICLIVGVGVLALREPHTART--------------------
Mvan_5329|M.vanbaalenii_PYR-1       LRTPYAVVAVICLVVGVGVLALREPHTART--------------------
Mb3755|M.bovis_AF2122/97            WVFLVNLPLGVFAVLAARRALVENRAAGRRRVPDVRGAVLLAFALGLLTL
Rv3728|M.tuberculosis_H37Rv         WVFLVNLPLGVFAVLAARRALVENRAAGRRRVPDVRGAVLLAFALGLLTL
MMAR_0729|M.marinum_M               LVFLVNIPLGIVAVLVAGRVLTESRASGRRRVPDLRGAMLLGVALGLMTL
MUL_3590|M.ulcerans_Agy99           LVFLVNIPLGIVAVLVAGRVLTESRASGRRRVPDLRGAMLLGVALGLMTL
MLBr_00556|M.leprae_Br4923          YVFWINIPLTAIAMLMIQVSLSAHDRGDELEKVDVVGGVLLAIALGLVVI
MAV_0138|M.avium_104                VRASFALAAAILALAAFAVVAAPQPSPVTAP-------------------
                                          :      :                                    

TH_0476|M.thermoresistible__bu      ---------------TGRLGVQR--LSLPPQVR------KVFAIASLAAF
MSMEG_5167|M.smegmatis_MC2_155      ---------------SGSIGLQR--LSVPPEVR------TVFVIAAIAAF
MAB_1299c|M.abscessus_ATCC_199      ---------------HGKLGRQR--LSLPPQVR------ATFAAAATAGF
Mflv_1450|M.gilvum_PYR-GCK          ---------------RGPIRIAR--PAVPAEIR------ADFWFSALGAM
Mvan_5329|M.vanbaalenii_PYR-1       ---------------RGPIRIAR--PAVPAEIR------ADFWFSALGAM
Mb3755|M.bovis_AF2122/97            GLIKGPDWGWASLPTSGSLLAAA--VAMVGFVMSSRHHPAPMVEPTLLRI
Rv3728|M.tuberculosis_H37Rv         GLIKGPDWGWASLPTSGSLLAAA--VAMVGFVMSSRHHPAPMVEPTLLRI
MMAR_0729|M.marinum_M               GLVKGPEWGWISTETIGSFVASS--VALVAFVASSRSHPTPLIDPAFLRV
MUL_3590|M.ulcerans_Agy99           GLVKGPEWGWISTATIGSFVASS--VALVAFVASSRSHPTPLIDPAFLRV
MLBr_00556|M.leprae_Br4923          GLYNPQPDSKQVLPSYGVPVLVGGIVATVAFAVWERCARTRLIDPAGVHI
MAV_0138|M.avium_104                ---------------ADPDGEETADAAPQGISR-------ALSWAMPLAP
                                                    .         :              :  .     

TH_0476|M.thermoresistible__bu      AGFAVTGLFTAVAPS-----------FLAEVIGVRNHAVAGAVAASIFAA
MSMEG_5167|M.smegmatis_MC2_155      AGFAVTGMYTAVAPS-----------FLSNVIGVDNHAVAGAVACSIFAA
MAB_1299c|M.abscessus_ATCC_199      AGFAALGSFTAVAPG-----------FLSGVLGIDNHAVAGASVFLTFGS
Mflv_1450|M.gilvum_PYR-GCK          ASWSVLGVLLSLYPS-----------LAAHHTHIDNLVFGGAVVATTAFA
Mvan_5329|M.vanbaalenii_PYR-1       ASWSVLGVLLSLYPS-----------LAARQTHIDNLVFGGAVVGTTAFA
Mb3755|M.bovis_AF2122/97            QSFVAGTGLTAVASAGFYAYLLTHVLFLNYVWGYTLLEAGMAVAPAALVA
Rv3728|M.tuberculosis_H37Rv         QSFVAGTGLTAVASAGFYAYLLTHVLFLNYVWGYTLLEAGMAVAPAALVA
MMAR_0729|M.marinum_M               RSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYSLLKAGFAIAPAALIA
MUL_3590|M.ulcerans_Agy99           RSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYSLLKAGFAIAPAALIA
MLBr_00556|M.leprae_Br4923          RPFLSALGASVAAGAALMVTLVNVELFGQGVLGMDQTQAAGLLVWFLIAL
MAV_0138|M.avium_104                WVFASATLGFVTIPG-------------RLHTALAAPVAAGTATLIVNGV
                                      :           .                        .   .      

TH_0476|M.thermoresistible__bu      SAVTQVLGASVSPR-RAVAVGCALLIVG-------------MVFLAAALV
MSMEG_5167|M.smegmatis_MC2_155      SAVTQVLANRVQPG-RAVAVGCAILIAG-------------MLILTAALL
MAB_1299c|M.abscessus_ATCC_199      SCVAQILTRRVAAA-KALLIGCTILLTG-------------MLLVVLALH
Mflv_1450|M.gilvum_PYR-GCK          AALAQLAATRVPAR-YAAIIGDAGMAAA-------------LLLTIPVLL
Mvan_5329|M.vanbaalenii_PYR-1       AALAQLAATRVPAR-YSAILGDAGMAAA-------------LLLTIPVLL
Mb3755|M.bovis_AF2122/97            AVVAAVLGRVADRHGYRFIVGIGALIWA-------------ASLLWYLKV
Rv3728|M.tuberculosis_H37Rv         AVVAAVLGRVADRHGYRFIVGIGALIWA-------------ASLLWYLKV
MMAR_0729|M.marinum_M               AVVAAVLGRIADQRGHRLVVMAGAIIWA-------------GSLVWYLQR
MUL_3590|M.ulcerans_Agy99           AVVAAVLGRIADQRGHRLVVMAGAIIWA-------------GSLVWYLQR
MLBr_00556|M.leprae_Br4923          PIGAVLGGWGATKAGDRTMTFVGLLITAGGYWLISHWPVDLLNYRRSIFG
MAV_0138|M.avium_104                SGAVQVLARALRWGPQAGTAGAVLAALG-------------YAVAAAAPS
                                    .  . :                     .                      

TH_0476|M.thermoresistible__bu      WSSLPALIATAVVAGAGQGLSFSRGLAAVSARTPS---------DQRGEV
MSMEG_5167|M.smegmatis_MC2_155      FSSLPALIAAAVVSGVGQGMSFSRGLAAIAEKTPP---------DRRAEV
MAB_1299c|M.abscessus_ATCC_199      TSSLPWYLASAVVVGIGQGISFSRGLAAIADRTPE---------DNRAEV
Mflv_1450|M.gilvum_PYR-GCK          THQWQLVFVAAALLGATFGLGFGGSLRHLSNVVPP---------ARRGET
Mvan_5329|M.vanbaalenii_PYR-1       THQWQLVFVAAALLGATFGLGFGGSLRHLSDVVPA---------GRRGET
Mb3755|M.bovis_AF2122/97            VGSQPDFLGEWLPGQILQGIGVGATFPLLGSAALARLAKGGSYATASAVT
Rv3728|M.tuberculosis_H37Rv         VGSQPDFLGEWLPGQILQGIGVGATFPLLGSAALARLAKGGSYATASAVT
MMAR_0729|M.marinum_M               VGTEPNFLREWLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASAVV
MUL_3590|M.ulcerans_Agy99           VGTEPNFLREWLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASAVV
MLBr_00556|M.leprae_Br4923          LFSVPTMYADLLVAGLGLGLVIGPLSSATLRVVPTAQHG-----IASAAV
MAV_0138|M.avium_104                TLTPALGVPLFVVLGCASGLCLREGLIDLEAAAPQR---------LRGGL
                                                      *: .          .              .  

TH_0476|M.thermoresistible__bu      SSTYFVVAYVALLVPVIGEGWAAHHWGLRTAGISFAVGVAVLAIGCLIAI
MSMEG_5167|M.smegmatis_MC2_155      SSTYFVVAYVAISLPVVGEGLSAQHWGLRPAGIAFALAVCVLAVICLVAI
MAB_1299c|M.abscessus_ATCC_199      TSSYFVVAYIGIALPVIGEGLAAQAWGLRTAGVTFALAVAALAALCLIAV
Mflv_1450|M.gilvum_PYR-GCK          MSAFYLLAYSAMAVPTLVAGWAATRWELASVFPWFAGIVSAACLGAAVAG
Mvan_5329|M.vanbaalenii_PYR-1       MSAFYLLAYSAMAVPTLIAGWAATRWDLAAVFPWFAGVVAAACMGAAIAG
Mb3755|M.bovis_AF2122/97            GTIRQVGAVIGVAVLVILVGTPAPGAAEEALRHRWALAAICFVAVGIGAL
Rv3728|M.tuberculosis_H37Rv         GTIRQVGAVIGVAVLVILVGTPAPGAAEEALRHGWALAAICFVAVGIGAL
MMAR_0729|M.marinum_M               STTRQLGAVIGVALLVILIGKPAPGTGVDALRHGWVLAAVCFAAVAVLAG
MUL_3590|M.ulcerans_Agy99           STTRQLGAVIGVALLVILIGKPAPGTGVEALRHGWVLAAVCFAAVAVLAG
MLBr_00556|M.leprae_Br4923          VVARMTGMLIGVAALTAWG-LYRFNQILAGLSTAVPPDATLIERAAAVAD
MAV_0138|M.avium_104                TGLFYVVTYIGFGLPLILASVRPG------VATAILSGMAVLAVTAAVGR
                                              ..                                    . 

TH_0476|M.thermoresistible__bu      LIQESRDPQAI---------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      LVEESRQRRAESAELSAST-------------------------------
MAB_1299c|M.abscessus_ATCC_199      IWQERPSRTEALAPVSTG--------------------------------
Mflv_1450|M.gilvum_PYR-GCK          LRSIRVARAA----------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       VRSVRLAQ------------------------------------------
Mb3755|M.bovis_AF2122/97            SLGRIRPVPAAVEPPPGPPVAPLGAR-RPPRPAPVASPAAAVAPTPK--T
Rv3728|M.tuberculosis_H37Rv         SLGRIRPVPAAVEPPPGPPVAPLGAR-RPPRPAPVASPAAAVAPTPK--T
MMAR_0729|M.marinum_M               FLGRTQQG-ADVAGAPESGVARAPARPQPVTPRPAAAPARLPQTTADGDL
MUL_3590|M.ulcerans_Agy99           FLGRTQQG-ADVAGAPESGVARAPARPQPVTPRPAAAPARPPQTTADGDL
MLBr_00556|M.leprae_Br4923          QAKRAYTMMYSDIFMITAIVCVIGALLGLLISSRKEHASEPKVPE-----
MAV_0138|M.avium_104                AARLRRDDHRQN--------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            SREVNLLEALRFA-----RPDTQQIELQAGSYLFHAGDVSDALYVVRSGR
Rv3728|M.tuberculosis_H37Rv         SREVNLLEALRFA-----RPDTQQIELQAGSYLFHAGDVSDALYVVRSGR
MMAR_0729|M.marinum_M               LRQLPLFAGLPAATMAELRHHTDEIELQAGSYLFHEADPSDALYVVRSGR
MUL_3590|M.ulcerans_Agy99           LRQLPLFAGLPAATMAELRHHTDEIELQAGSYLFHEVDPSDALYVVRSGR
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            LQVLAGDGAKDEVVAELGRGQVVGELGVLLDAPRSASVRAVRDSSLMRVT
Rv3728|M.tuberculosis_H37Rv         LQVLAGDGAKDEVVAELGRGQVVGELGVLLDAPRSASVRAVRDSSLMRVT
MMAR_0729|M.marinum_M               LRVVQ----RDLVLRELGRGEVVGELGLLIDAPRSASVQAMRDSVLIRLS
MUL_3590|M.ulcerans_Agy99           LRVVQ----RDLVLRELGRGEVVGELGLLIDAPRSASVQAMRDFVLIRLS
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            KAEFAKIADAGVLGALAGVLAKRQHQTR--VASQRTTPEVVVAVVGVDAN
Rv3728|M.tuberculosis_H37Rv         KAEFAKIADAGVLGALAGVLAKRQHQTR--VASQRTTPEVVVAVVGVDAN
MMAR_0729|M.marinum_M               KAQFNRIADRGVLAALVGTLATRLHTAPPPTVGRPASPEAVIAVIGLGAA
MUL_3590|M.ulcerans_Agy99           KAQFNRIADRGVLAALVGTLATRLHTAPPPTVDRPASPEAVIAVIGLGAA
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            APVAMVATELCRALSTRLRAVAPGRVDCDGLERAEQTADRVVLHAAVGDA
Rv3728|M.tuberculosis_H37Rv         APVAMVATELCRALSTRLRAVAPGRVDCDGLERAEQTADRVVLHAAVGDA
MMAR_0729|M.marinum_M               VPVRPVALALLNALSARVTAVDPGRVDRAGLERAEASADKVVLHASANDT
MUL_3590|M.ulcerans_Agy99           VPVRPVALALLNALSARVTAVDPGRVDRAGLERAEASADKVVLDASANDT
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            RWREFCLRVADRVVLVASNPAVPVAPLPTRATGADLVLAGRPAGREHRRA
Rv3728|M.tuberculosis_H37Rv         RWREFCLRVADRVVLVASNPAVPVAPLPTRATGADLVLAGRPAGREHRRA
MMAR_0729|M.marinum_M               GWRDFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDRSR
MUL_3590|M.ulcerans_Agy99           GWRDFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDRSR
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            WEQLITPRSMHVVRREFVADDLRVLATRIAGRSVGLVLSGGAARACAHLG
Rv3728|M.tuberculosis_H37Rv         WEQLITPRSMHVVRREFVADDLRVLATRIAGRSVGLVLSGGAARACAHLG
MMAR_0729|M.marinum_M               WEELISPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAHLG
MUL_3590|M.ulcerans_Agy99           WEELIPPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAHLG
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            VLEELEAAGVTVDRFAGTSMGAIIAALAASGLDAAGVDAQIYEHFVRKS-
Rv3728|M.tuberculosis_H37Rv         VLEELEAAGVTVDRFAGTSMGAIIAALAASGLDAAGVDAQIYEHFVRKS-
MMAR_0729|M.marinum_M               VLDELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRHNP
MUL_3590|M.ulcerans_Agy99           VLDELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRHNP
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            HGDYTLPSKGLIRGKRTQSTLRTIFGDHLVEELPKHFRCVSVDLLARRPV
Rv3728|M.tuberculosis_H37Rv         HGDYTLPSKGLIRGKRTQSTLRTIFGDHLVEELPKHFRCVSVDLLARRPV
MMAR_0729|M.marinum_M               LGDYTLPSKGLVRGRRTMALLREAYSGRMVEELPKEFRCVSVDLLARQAV
MUL_3590|M.ulcerans_Agy99           LGDYTLPSKGLVRGRRTMGLLREAYSGRMVEELPKEFRCVSVDLLARQAV
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            VHRQGPLADVVGCSMRLPFLYAPLPYGGTLHVDGGVLDNVPVTTLVGKDG
Rv3728|M.tuberculosis_H37Rv         VHRQGPLADVVGCSMRLPFLYAPLPYGGTLHVDGGVLDNVPVTTLVGKDG
MMAR_0729|M.marinum_M               VHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRAEG
MUL_3590|M.ulcerans_Agy99           VHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRAEG
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            PLIAVNVASGGNPSPASGGHRRGKPRVPGLTDTLLRTMTISSAMASEKVL
Rv3728|M.tuberculosis_H37Rv         PLIAVNVASGGNPSPASGGHRRGKPRVPGLTDTLLRTMTISSAMASEKVL
MMAR_0729|M.marinum_M               PMIAVSVGFGGNPSGGQP-RRSGPIQVPGIGDTLMRTMMMGSRTVADAAQ
MUL_3590|M.ulcerans_Agy99           PMIAVSVGFGGNPSGGQP-RRSGPIQVPGIGDTLMRTMMMGSRTVADAAQ
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            AQADLVIKPNPIGVGLMEYHQIDRAREAGRIAAREALPQIMELVHG----
Rv3728|M.tuberculosis_H37Rv         AQADLVIKPNPIGVGLMEYHQIDRAREAGRIAAREALPQIMELVHG----
MMAR_0729|M.marinum_M               AEALVVIRPDTRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGPAG
MUL_3590|M.ulcerans_Agy99           AEALVVIRPDTRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGPAG
MLBr_00556|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

TH_0476|M.thermoresistible__bu      ----------------------
MSMEG_5167|M.smegmatis_MC2_155      ----------------------
MAB_1299c|M.abscessus_ATCC_199      ----------------------
Mflv_1450|M.gilvum_PYR-GCK          ----------------------
Mvan_5329|M.vanbaalenii_PYR-1       ----------------------
Mb3755|M.bovis_AF2122/97            ----------------------
Rv3728|M.tuberculosis_H37Rv         ----------------------
MMAR_0729|M.marinum_M               QTTGRAIDRSARALRTDARRPA
MUL_3590|M.ulcerans_Agy99           QTTGRAIDRSARALRTDARRPA
MLBr_00556|M.leprae_Br4923          ----------------------
MAV_0138|M.avium_104                ----------------------