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M. thermoresistible (build 8) TH_3831 (-)

annotation: putative transcriptional regulator, TetR family
coordinates: 1234380 - 1234958
length: 193

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3831--100% (193)putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_1278-4e-2241.73% (139) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY
M. thermoresistible (build 8)TH_2839-8e-1331.85% (157) PUTATIVE transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0149-7e-3038.34% (193) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0744-2e-3339.38% (193) TetR family transcriptional regulator
M. tuberculosis H37RvRv0144-7e-3038.34% (193) TetR family transcriptional regulator
M. leprae Br4923MLBr_00815-9e-0935.00% (80) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_1149-5e-1028.78% (139) TetR family transcriptional regulator
M. marinum MMMAR_0355-2e-2938.34% (193) TetR family transcriptional regulator
M. avium 104MAV_5151-6e-2733.85% (195) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_0092-1e-3238.14% (194) transcriptional regulatory protein
M. ulcerans Agy99MUL_4765-1e-2938.34% (193) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2776-5e-2936.56% (186) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0149|M.bovis_AF2122/97            MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv         MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MMAR_0355|M.marinum_M               --------------------------------------------------
MUL_4765|M.ulcerans_Agy99           --------------------------------------------------
MAV_5151|M.avium_104                --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155      --------------------------------------------------
TH_3831|M.thermoresistible__bu      --------------------------------------------------
Mvan_2776|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1149|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00815|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0149|M.bovis_AF2122/97            ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKAD--ETRKRILHAAR
Rv0144|M.tuberculosis_H37Rv         ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKAD--ETRKRILHAAR
MMAR_0355|M.marinum_M               -------------------MQLTASRGPGRPPAAKAD--DTRRRIVGAAR
MUL_4765|M.ulcerans_Agy99           ------------------MMQLTASRGPGRPPAAKAD--DTRRRIVGAAR
MAV_5151|M.avium_104                -------------------MLPRGNRRPGRPPAAKAD--ETRQRIIQAAR
Mflv_0744|M.gilvum_PYR-GCK          -------------MWHNFNVPYTASRGPGRPPAAKAA--ETRERILRAAR
MSMEG_0092|M.smegmatis_MC2_155      -------------------MAHIASRGPGRPPAAKAA--ETRERILSAAR
TH_3831|M.thermoresistible__bu      ----------------------------MRPARTASS--DTRARILEAAR
Mvan_2776|M.vanbaalenii_PYR-1       ---------------------MPAVRRPGRPVGANSD--QTRRTILCAAR
MAB_1149|M.abscessus_ATCC_1997      ------------------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVAR
MLBr_00815|M.leprae_Br4923          -MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVAS
                                                                 .         . *  :: .* 

Mb0149|M.bovis_AF2122/97            QVFSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVI
Rv0144|M.tuberculosis_H37Rv         QVFSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVI
MMAR_0355|M.marinum_M               EVFSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVV
MUL_4765|M.ulcerans_Agy99           EVFSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVV
MAV_5151|M.avium_104                LVFSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVI
Mflv_0744|M.gilvum_PYR-GCK          EVFSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIV
MSMEG_0092|M.smegmatis_MC2_155      EVFSELGYDAATFQAIAIRADLTRPAINHYFGSKRVLYREVVEQTNATVI
TH_3831|M.thermoresistible__bu      RIIVERGYPAATCQGIARAAGVSRPTLHYYFASREEIYDCLVEQS-RNLL
Mvan_2776|M.vanbaalenii_PYR-1       DVIAEHGYRAATFQQIALRAGVSRPTLHYYFATREQLYEVLLADVRAEVA
MAB_1149|M.abscessus_ATCC_1997      SLFAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLL
MLBr_00815|M.leprae_Br4923          DVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
                                     :: : ** .:  : **  *.:::*.:  :*. :  ::  ::      : 

Mb0149|M.bovis_AF2122/97            VAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPE
Rv0144|M.tuberculosis_H37Rv         VAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPE
MMAR_0355|M.marinum_M               AAGVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPE
MUL_4765|M.ulcerans_Agy99           AAGVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPE
MAV_5151|M.avium_104                GVGIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPE
Mflv_0744|M.gilvum_PYR-GCK          SEAIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPE
MSMEG_0092|M.smegmatis_MC2_155      AAGVARAREATSLLGRLSAFFAAAMDAESADRSSAAFLVTSVLESQRHPD
TH_3831|M.thermoresistible__bu      AECAERAMRYDTLVERLTEFGLRLREVDSRDRSTIAFLISARLEGMRNRE
Mvan_2776|M.vanbaalenii_PYR-1       RCAAEATLAG-SLLRQLEVFIAEMHRLGGAEPALMGLVVTARVD-HRGVL
MAB_1149|M.abscessus_ATCC_1997      DG-ITSSLTSYRSRVRLEQVALALLSYIEERTDGFRILIRDSPPGVSSGT
MLBr_00815|M.leprae_Br4923          SSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFE-NDNITEPRV
                                                   :*                   ::            

Mb0149|M.bovis_AF2122/97            LSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVG
Rv0144|M.tuberculosis_H37Rv         LSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVG
MMAR_0355|M.marinum_M               LRRSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVG
MUL_4765|M.ulcerans_Agy99           LRRSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVG
MAV_5151|M.avium_104                WNTAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVG
Mflv_0744|M.gilvum_PYR-GCK          LINDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMG
MSMEG_0092|M.smegmatis_MC2_155      LVSEEQDALLNSRKFVAWAVNDAIERGELTTDTDIPAIVEMLVAVMWGMG
TH_3831|M.thermoresistible__bu      LG---EDPAMALREFFTELLADAVAAGELPSDIDIESAVEVMYTVLWGLG
Mvan_2776|M.vanbaalenii_PYR-1       RHEAATAVVATVHAFFDAVVVDAVRRGELAFDTDAHAVADLLGALFWGLV
MAB_1149|M.abscessus_ATCC_1997      YSSLLNDAVSQVSSILAGDFQRRGLDAEMAPLYAQALVGQVSMTAQWWLD
MLBr_00815|M.leprae_Br4923          AAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLD
                                                  ..           .                    : 

Mb0149|M.bovis_AF2122/97            FYIG--FVGSYQRMATITDSFQQLLAGTLWRPPT------
Rv0144|M.tuberculosis_H37Rv         FYIG--FVGSYQRMATITDSFQQLLAGTLWRPPT------
MMAR_0355|M.marinum_M               FYAG--FVGSYRDMENILDTLCKMMAGTLWKPRS------
MUL_4765|M.ulcerans_Agy99           FYAG--FVGSYRDMENILDTLCKMMAGTLWKPRS------
MAV_5151|M.avium_104                LYAG--YVETYQEMLAVTGMLRQLLEGALWRPGS------
Mflv_0744|M.gilvum_PYR-GCK          FYAG--FVGDRSDLSAVVHKLELLLAGKLWNVAD------
MSMEG_0092|M.smegmatis_MC2_155      FYAG--YVGRSEELAAIVDKFEMLMANKLWQLRD------
TH_3831|M.thermoresistible__bu      FYTG--FVERSTDMLVLAEQLENLFASA------------
Mvan_2776|M.vanbaalenii_PYR-1       FHAG--FISGADGAPEIARQLLRMVGFGLLDTPEPASVDA
MAB_1149|M.abscessus_ATCC_1997      AREPKKEVVAAHIVNLCWHGLKHLEADPQLHEE-------
MLBr_00815|M.leprae_Br4923          TNRP---ISKSDAVEGTVQFAWGGLSHVPLTRL-------
                                           :