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VSRNVLTVIGVGGMGQAIARRLGSGKTVVLADNNADTLASVAESLAAEGHDVRSRGVDVCAAESVHDLAQ YAATLGAVTQLAHTAGLSPTQASAQAILAVDLVAVALVLQEFGAVIAPGGAGVIIASMAGHLLPPPSAEQ EHDLAHRPPGQLLELDFVGSIVEPAFAYPFAKQANSIRVRAASRQWGQREARVNSISPDIISTPMGQQEL ASPVGDGMRAMIAMSGTGRIGTPDDIAAAAAFLLGPEATFITGADLLVDGGVVAAIRANG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4870 | - | - | 100% (270) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_2885 | - | 3e-13 | 26.64% (274) | short-chain type dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_0478 | - | 6e-13 | 26.48% (253) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 4e-14 | 27.72% (267) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1024 | - | 2e-26 | 30.94% (265) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 4e-14 | 27.72% (267) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-08 | 25.37% (268) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0691 | - | 2e-81 | 59.47% (264) | short chain dehydrogenase |
| M. marinum M | MMAR_0243 | - | 1e-141 | 95.54% (269) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_5240 | - | 4e-28 | 31.56% (263) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6662 | - | 3e-28 | 31.95% (266) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_0784 | - | 1e-26 | 32.05% (259) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5812 | - | 6e-26 | 30.83% (266) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4870|M.ulcerans_Agy99 -------------------MSRNVLTVIGVGGMGQAIARRL-GSGKTVVL
MMAR_0243|M.marinum_M -------------------MSRDVLTVIGVGGMGQAIARRL-GSGKTVLL
MAB_0691|M.abscessus_ATCC_1997 -------------------MPDEVVVVIGVGGMGRVIARRQ-GIGKALLL
MAV_5240|M.avium_104 ----------------------MSVITGGAGGMGVATAKVV-GRDHTLVL
Mvan_5812|M.vanbaalenii_PYR-1 -------------------MTAVSLITGGAGGMGLATAKVV-GQDRAVVL
MSMEG_6662|M.smegmatis_MC2_155 -------------------MRTVSVITGGAGGMGVATAKIV-GKEHAVVL
TH_0784|M.thermoresistible__bu --------------------------------MGQATARVV-GREHAVVL
Mflv_1024|M.gilvum_PYR-GCK -------------------MSAVSLITGGAGGMGLATAKVV-GRDHSVVL
Mb2882c|M.bovis_AF2122/97 MMDLSQRLAG-----------RVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv MMDLSQRLAG-----------RVAVITGGGSGIGLAAGRRMRAEGATIVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
:* . .: . : :
MUL_4870|M.ulcerans_Agy99 ADNNADTLASVAESLAAEGHDVRSRGVDVCAAESVHDLAQYAAT-LGAVT
MMAR_0243|M.marinum_M ADNNADTLASVSETLAAEGHDVKSRGVDVCAAESVHDLAQYAAT-LGAVT
MAB_0691|M.abscessus_ATCC_1997 ADHNEQALQAVVDELKADGHNVIGQRVDVSSRASVSGLAQAAAG-LGRVA
MAV_5240|M.avium_104 CDVRQDRLTAATAALAELGMTPTAVNCDVTDRRAVAQLFDTAAG-LGTVV
Mvan_5812|M.vanbaalenii_PYR-1 CDVRQDRLDGAAAALKDLGVAVTAVNCDVTDRRAVDALFETVSR-LGTLV
MSMEG_6662|M.smegmatis_MC2_155 CDVRQDRLDTAATALAEVGITPTVVKCDVTDRHAVNRLFATTAG-LGTLA
TH_0784|M.thermoresistible__bu CDVRQDRLDTAAAVLRDDGITATPVHCDVTDPQAVDRLFKETAG-IGELA
Mflv_1024|M.gilvum_PYR-GCK CDVRQERLDAAAAELAGLGISATTVHCDVTDRDAVGRLFDGAAV-AGTLA
Mb2882c|M.bovis_AF2122/97 GDVDVEAGGAAADELSGL-----FVPTDVCDEDAVNGLFDGAAETYGRID
Rv2857c|M.tuberculosis_H37Rv GDVDVEAGGAAADELSGL-----FVPTDVCDEDAVNGLFDGAAETYGRID
MLBr_01807|M.leprae_Br4923 ----THRASVVPDWFFG-------VECDVTDNDAIGAAFKAVEEHQGPVE
. . : ** :: . * :
MUL_4870|M.ulcerans_Agy99 QLAHTAGLSPTQASAQAILAVDLVAVALVLQEFGAVIAPGGAGVIIASMA
MMAR_0243|M.marinum_M QLAHTAGLSPAQASAQAILAVDLLGVALVLQEFGAVIAPGGAGVIIASMA
MAB_0691|M.abscessus_ATCC_1997 QVAHTAGLSPAQSPTAAILAVDLVGVALVVEEFGKIVASGGAGVVIASMA
MAV_5240|M.avium_104 SVIHTAGVSPSMGPADYVMRTNAIGTLNVNEAFYAVAGDGSVIVNVASMA
Mvan_5812|M.vanbaalenii_PYR-1 SVIHTAGVSPSMGDAEYVMRTNALGTLNVDEAFYGAATDGAAIVNVASMA
MSMEG_6662|M.smegmatis_MC2_155 SVIHTAGVSPSMGDAEYVIRTNAIGTATINEAFYAAAPRGSAIVNVASMA
TH_0784|M.thermoresistible__bu SVIHTAGVSPSMGSAEYVMRTNAVGTVHVNEAFLRTAGAGAAIVNVASMA
Mflv_1024|M.gilvum_PYR-GCK SVIHTAGVSPSMGDAEYVMRTNALGTVNVGEQFFARAGEGAALVNVASMA
Mb2882c|M.bovis_AF2122/97 IAFNNAGISPPE---------DNLIENTELAAWQRVQDVNLKSVYLCCRA
Rv2857c|M.tuberculosis_H37Rv IAFNNAGISPPE---------DNLIENTELAAWQRVQDVNLKSVYLCCRA
MLBr_01807|M.leprae_Br4923 VLVANAGITS-----------DMLIMRMSEEQFQKVIDVNLTGVFRVAKL
.**::. : : : . * .
MUL_4870|M.ulcerans_Agy99 GHLLPPPSAEQ------EHDLAHRPPGQLLELDFVGSIVEPAFAYPFAKQ
MMAR_0243|M.marinum_M GHLLPPPSAEQ------ERELAHRPPGQLLELDFVGSIVEPAFAYPFAKQ
MAB_0691|M.abscessus_ATCC_1997 GHMPYELTAEQ------EQELGTTHAEDLLSLPYVRDIEHPAVAYQVSKR
MAV_5240|M.avium_104 AHMLPAEIVPTAQFPLALSDADAFMDAMLAACEIAPEQARSGLAYAVSKS
Mvan_5812|M.vanbaalenii_PYR-1 AYLLPAELIPTSAFPLALQDTEAFMTEMLAACAIAPEEARSGISYAISKS
MSMEG_6662|M.smegmatis_MC2_155 AHLLPEEMIPTGLFPQAMQAPEVFLKDMLAACEIVPEEARSGIAYALSKS
TH_0784|M.thermoresistible__bu AHMLPAEMVRTNLFARALTDLDGFLSEMLATCDAFPEEGRSGIAYALSKS
Mflv_1024|M.gilvum_PYR-GCK AHILPAELIPTAVFPAALQDPDTFMAEMLTACEIAPEEARSGIAYALSKS
Mb2882c|M.bovis_AF2122/97 ALRH-------------MVLAGKGSIVNTASFVAVMGSATSQISYTASKG
Rv2857c|M.tuberculosis_H37Rv ALRH-------------MVLAGKGSIVNTASFVAVMGSATSQISYTASKG
MLBr_01807|M.leprae_Br4923 ASRN-------------MIKQRFGRYIFMGSVVGLSG-VPGQANYAASKS
. * :*
MUL_4870|M.ulcerans_Agy99 ANSIRVRAASRQWGQREARVNSISPDIISTPMGQQELASPVGDGMRAMIA
MMAR_0243|M.marinum_M ANSIRVRAASRQWGQREARVNSISPGIISTPMGQQELASPVGDGMRAMIA
MAB_0691|M.abscessus_ATCC_1997 ANHIRVRFAARQWGTRGARINSISPGVVSTPMGHQELASETGAITKAMVD
MAV_5240|M.avium_104 FVKWYSQSQAERFNARGLRIVSVSPGSIDTEMGRLEENAGAG----AMVA
Mvan_5812|M.vanbaalenii_PYR-1 FVRWYSSSQAERFNGRGLRIVSVSPGSVDTEMGRLEEQAGAG----AMVA
MSMEG_6662|M.smegmatis_MC2_155 FVRWYSSSQAERFTGRGLRIVSVSPGSVDTEMGRLEEKAGAG----ALVA
TH_0784|M.thermoresistible__bu FVKWYSAAQAERFNARGLRIVSVSPGSIDTEMGRLEEQAGAG----AMVA
Mflv_1024|M.gilvum_PYR-GCK FVRWYSVAQAERFNGKGLRILSVSPGSIDTEMGRLEEQAGAG----AMVA
Mb2882c|M.bovis_AF2122/97 GVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPER-AARRMV
Rv2857c|M.tuberculosis_H37Rv GVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPER-AARRMV
MLBr_01807|M.leprae_Br4923 GLIGMARSLARELGSRSITANVVAPGFIDTEMTRAMDSKYQEA-ALQ---
. . : :.*. :.* : :
MUL_4870|M.ulcerans_Agy99 MSGTGRIGTPDDIAAAAAFLLGPEATFITGADLLVDGGVVAAIRANG---
MMAR_0243|M.marinum_M MSGTGRIGTPDDIAAAAAFLLGPEATFITGADLLVDGGVVAAIRASR---
MAB_0691|M.abscessus_ATCC_1997 GSASRRIGTSDDIAAAAAFLLGPESSYVTGTDLLVDGGVIAAVRSGQLFN
MAV_5240|M.avium_104 DAAVPRWGKPEEMAELLAFCASDKAGYLTGTDILNDGGVIASMTERARVT
Mvan_5812|M.vanbaalenii_PYR-1 DAAVPRWGKPEEMAELLAFCAGDKAGYLTGTDILNDGGVVASMTERARLA
MSMEG_6662|M.smegmatis_MC2_155 DAAVPRWGTPEEMAELFAFCASDRAGYLTGTDILNDGGVVASMRERARVA
TH_0784|M.thermoresistible__bu DAAVPRWGTPEEMAELLAFCASAKASYLTGTDILNDGGVIASMTERARAA
Mflv_1024|M.gilvum_PYR-GCK DAAVPRWGTAEEMADLLAFCASRKAGYLTGTDILNDGGVIASMTERTRLA
Mb2882c|M.bovis_AF2122/97 HVPLGRFAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL---
Rv2857c|M.tuberculosis_H37Rv HVPLGRFAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL---
MLBr_01807|M.leprae_Br4923 AIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-------
* . :::* :* . : :::.: : ***: .
MUL_4870|M.ulcerans_Agy99 ------
MMAR_0243|M.marinum_M ------
MAB_0691|M.abscessus_ATCC_1997 ------
MAV_5240|M.avium_104 AAG---
Mvan_5812|M.vanbaalenii_PYR-1 AASSS-
MSMEG_6662|M.smegmatis_MC2_155 AEQQQQ
TH_0784|M.thermoresistible__bu AETQ--
Mflv_1024|M.gilvum_PYR-GCK SQ----
Mb2882c|M.bovis_AF2122/97 ------
Rv2857c|M.tuberculosis_H37Rv ------
MLBr_01807|M.leprae_Br4923 ------