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M. thermoresistible (build 8) TH_0784 (-)

annotation: short chain dehydrogenase
coordinates: 1640464 - 1641264
length: 267

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0784--100% (267)short chain dehydrogenase
M. thermoresistible (build 8)TH_3914-4e-1525.87% (259) PUTATIVE 3-alpha-hydroxysteroid dehydrogenase
M. thermoresistible (build 8)TH_3912-9e-1327.86% (262) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1963c-6e-1227.39% (241) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1024-1e-11076.14% (264) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1928c-6e-1227.39% (241) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG14e-1025.94% (212) 3-oxoacyl-
M. abscessus ATCC 19977MAB_0691-2e-2934.36% (259) short chain dehydrogenase
M. marinum MMMAR_0243-6e-2731.82% (264) short-chain type dehydrogenase/reductase
M. avium 104MAV_5240-1e-10974.90% (263) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_6662-1e-11174.81% (266) short chain dehydrogenase
M. ulcerans Agy99MUL_4870-1e-2632.05% (259) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5812-1e-10874.14% (263) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


MAV_5240|M.avium_104                ------------MSVITGGAGGMG----VATAKV-VGRDHTLVLCDVRQD
Mvan_5812|M.vanbaalenii_PYR-1       ---------MTAVSLITGGAGGMG----LATAKV-VGQDRAVVLCDVRQD
MSMEG_6662|M.smegmatis_MC2_155      ---------MRTVSVITGGAGGMG----VATAKI-VGKEHAVVLCDVRQD
TH_0784|M.thermoresistible__bu      ----------------------MG----QATARV-VGREHAVVLCDVRQD
Mflv_1024|M.gilvum_PYR-GCK          ---------MSAVSLITGGAGGMG----LATAKV-VGRDHSVVLCDVRQE
MMAR_0243|M.marinum_M               ---------MSRDVLTVIGVGGMG----QAIARR-LGSGKTVLLADNNAD
MUL_4870|M.ulcerans_Agy99           ---------MSRNVLTVIGVGGMG----QAIARR-LGSGKTVVLADNNAD
MAB_0691|M.abscessus_ATCC_1997      ---------MPDEVVVVIGVGGMG----RVIARR-QGIGKALLLADHNEQ
Mb1963c|M.bovis_AF2122/97           MSVLDLFDLHGKRALITGASTGIG----KRVALAYVEAGAQVAIAARHLD
Rv1928c|M.tuberculosis_H37Rv        MSVLDLFDLHGKRALITGASTGIG----KRVALAYVEAGAQVAIAARHLD
MLBr_01807|M.leprae_Br4923          ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
                                                           *       :         : :.  .  

MAV_5240|M.avium_104                RLTAATAALAELGMTPT----AVNCDVTDRRAVAQLFDTAAGLGTVVSVI
Mvan_5812|M.vanbaalenii_PYR-1       RLDGAAAALKDLGVAVT----AVNCDVTDRRAVDALFETVSRLGTLVSVI
MSMEG_6662|M.smegmatis_MC2_155      RLDTAATALAEVGITPT----VVKCDVTDRHAVNRLFATTAGLGTLASVI
TH_0784|M.thermoresistible__bu      RLDTAAAVLRDDGITAT----PVHCDVTDPQAVDRLFKETAGIGELASVI
Mflv_1024|M.gilvum_PYR-GCK          RLDAAAAELAGLGISAT----TVHCDVTDRDAVGRLFDGAAVAGTLASVI
MMAR_0243|M.marinum_M               TLASVSETLAAEGHDVK----SRGVDVCAAESVHDLAQYAATLGAVTQLA
MUL_4870|M.ulcerans_Agy99           TLASVAESLAAEGHDVR----SRGVDVCAAESVHDLAQYAATLGAVTQLA
MAB_0691|M.abscessus_ATCC_1997      ALQAVVDELKADGHNVI----GQRVDVSSRASVSGLAQAAAGLGRVAQVA
Mb1963c|M.bovis_AF2122/97           ALEKLADEIGTSGGKVV----PVCCDVSQHQQVTSMLDQVT--------A
Rv1928c|M.tuberculosis_H37Rv        ALEKLADEIGTSGGKVV----PVCCDVSQHQQVTSMLDQVT--------A
MLBr_01807|M.leprae_Br4923          VADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVE--------E
                                            :   .            **     :      .          

MAV_5240|M.avium_104                HTAGVSPSMGPADYVMRTNAIGTLNVNEAFYAVAGDGSVIVNVASMAAHM
Mvan_5812|M.vanbaalenii_PYR-1       HTAGVSPSMGDAEYVMRTNALGTLNVDEAFYGAATDGAAIVNVASMAAYL
MSMEG_6662|M.smegmatis_MC2_155      HTAGVSPSMGDAEYVIRTNAIGTATINEAFYAAAPRGSAIVNVASMAAHL
TH_0784|M.thermoresistible__bu      HTAGVSPSMGSAEYVMRTNAVGTVHVNEAFLRTAGAGAAIVNVASMAAHM
Mflv_1024|M.gilvum_PYR-GCK          HTAGVSPSMGDAEYVMRTNALGTVNVGEQFFARAGEGAALVNVASMAAHI
MMAR_0243|M.marinum_M               HTAGLSPAQASAQAILAVDLLGVALVLQEFGAVIAPGGAGVIIASMAGHL
MUL_4870|M.ulcerans_Agy99           HTAGLSPTQASAQAILAVDLVAVALVLQEFGAVIAPGGAGVIIASMAGHL
MAB_0691|M.abscessus_ATCC_1997      HTAGLSPAQSPTAAILAVDLVGVALVVEEFGKIVASGGAGVVIASMAGHM
Mb1963c|M.bovis_AF2122/97           ELGGIDIAVCNAGIITVTPMLDMP--LEEFQRLQNTNVTGVFLTAQAAAK
Rv1928c|M.tuberculosis_H37Rv        ELGGIDIAVCNAGIITVTPMLDMP--LEEFQRLQNTNVTGVFLTAQAAAK
MLBr_01807|M.leprae_Br4923          HQGPVEVLVANAG--ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASR
                                    . . :.     :        :      : *      . . *  .:  .  

MAV_5240|M.avium_104                LPAEIVPTAQFPLALSDADAFMDAMLAACEIAPEQARSGLAYAVSKSFVK
Mvan_5812|M.vanbaalenii_PYR-1       LPAELIPTSAFPLALQDTEAFMTEMLAACAIAPEEARSGISYAISKSFVR
MSMEG_6662|M.smegmatis_MC2_155      LPEEMIPTGLFPQAMQAPEVFLKDMLAACEIVPEEARSGIAYALSKSFVR
TH_0784|M.thermoresistible__bu      LPAEMVRTNLFARALTDLDGFLSEMLATCDAFPEEGRSGIAYALSKSFVK
Mflv_1024|M.gilvum_PYR-GCK          LPAELIPTAVFPAALQDPDTFMAEMLTACEIAPEEARSGIAYALSKSFVR
MMAR_0243|M.marinum_M               LPPPSAEQ------ERELAHRPPGQLLELDFVGSIVEPAFAYPFAKQANS
MUL_4870|M.ulcerans_Agy99           LPPPSAEQ------EHDLAHRPPGQLLELDFVGSIVEPAFAYPFAKQANS
MAB_0691|M.abscessus_ATCC_1997      PYELTAEQ------EQELGTTHAEDLLSLPYVRDIEHPAVAYQVSKRANH
Mb1963c|M.bovis_AF2122/97           AMVK-----------QGQGGVIINTASMSGHIINVPQQVSHYCASKAAVI
Rv1928c|M.tuberculosis_H37Rv        AMVK-----------QGQGGVIINTASMSGHIINVPQQVSHYCASKAAVI
MLBr_01807|M.leprae_Br4923          NMIKQRFG----------RYIFMGSVVGLSGVPGQAN----YAASKSGLI
                                                                        .    *  :*    

MAV_5240|M.avium_104                WYSQSQAERFNARGLRIVSVSPGSIDTEMGRLEENAGAG----AMVADAA
Mvan_5812|M.vanbaalenii_PYR-1       WYSSSQAERFNGRGLRIVSVSPGSVDTEMGRLEEQAGAG----AMVADAA
MSMEG_6662|M.smegmatis_MC2_155      WYSSSQAERFTGRGLRIVSVSPGSVDTEMGRLEEKAGAG----ALVADAA
TH_0784|M.thermoresistible__bu      WYSAAQAERFNARGLRIVSVSPGSIDTEMGRLEEQAGAG----AMVADAA
Mflv_1024|M.gilvum_PYR-GCK          WYSVAQAERFNGKGLRILSVSPGSIDTEMGRLEEQAGAG----AMVADAA
MMAR_0243|M.marinum_M               IRVRAASRQWGQREARVNSISPGIISTPMGQQELASPVGDGMRAMIAMSG
MUL_4870|M.ulcerans_Agy99           IRVRAASRQWGQREARVNSISPDIISTPMGQQELASPVGDGMRAMIAMSG
MAB_0691|M.abscessus_ATCC_1997      IRVRFAARQWGTRGARINSISPGVVSTPMGHQELASETGAITKAMVDGSA
Mb1963c|M.bovis_AF2122/97           HLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQPL-----WEPKIP
Rv1928c|M.tuberculosis_H37Rv        HLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQPL-----WEPKIP
MLBr_01807|M.leprae_Br4923          GMARSLARELGSRSITANVVAPGFIDTEMTRAMDSKYQE----AALQAIP
                                          : .   :      ::*. : * : .                   

MAV_5240|M.avium_104                VPRWGKPEEMAELLAFCASDKAGYLTGTDILNDGGVIASMTERARVTAAG
Mvan_5812|M.vanbaalenii_PYR-1       VPRWGKPEEMAELLAFCAGDKAGYLTGTDILNDGGVVASMTERARLAAAS
MSMEG_6662|M.smegmatis_MC2_155      VPRWGTPEEMAELFAFCASDRAGYLTGTDILNDGGVVASMRERARVAAEQ
TH_0784|M.thermoresistible__bu      VPRWGTPEEMAELLAFCASAKASYLTGTDILNDGGVIASMTERARAAAET
Mflv_1024|M.gilvum_PYR-GCK          VPRWGTAEEMADLLAFCASRKAGYLTGTDILNDGGVIASMTERTRLASQ-
MMAR_0243|M.marinum_M               TGRIGTPDDIAAAAAFLLGPEATFITGADLLVDGGVVAAIRASR------
MUL_4870|M.ulcerans_Agy99           TGRIGTPDDIAAAAAFLLGPEATFITGADLLVDGGVVAAIRANG------
MAB_0691|M.abscessus_ATCC_1997      SRRIGTSDDIAAAAAFLLGPESSYVTGTDLLVDGGVIAAVRSGQLFN---
Mb1963c|M.bovis_AF2122/97           LGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP-----------
Rv1928c|M.tuberculosis_H37Rv        LGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP-----------
MLBr_01807|M.leprae_Br4923          LGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH----------
                                      * *  :::*    :  .  : :::*: :  ***               

MAV_5240|M.avium_104                ---
Mvan_5812|M.vanbaalenii_PYR-1       SS-
MSMEG_6662|M.smegmatis_MC2_155      QQQ
TH_0784|M.thermoresistible__bu      Q--
Mflv_1024|M.gilvum_PYR-GCK          ---
MMAR_0243|M.marinum_M               ---
MUL_4870|M.ulcerans_Agy99           ---
MAB_0691|M.abscessus_ATCC_1997      ---
Mb1963c|M.bovis_AF2122/97           ---
Rv1928c|M.tuberculosis_H37Rv        ---
MLBr_01807|M.leprae_Br4923          ---