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SRDVLTVIGVGGMGQAIARRLGSGKTVLLADNNADTLASVSETLAAEGHDVKSRGVDVCAAESVHDLAQY AATLGAVTQLAHTAGLSPAQASAQAILAVDLLGVALVLQEFGAVIAPGGAGVIIASMAGHLLPPPSAEQE RELAHRPPGQLLELDFVGSIVEPAFAYPFAKQANSIRVRAASRQWGQREARVNSISPGIISTPMGQQELA SPVGDGMRAMIAMSGTGRIGTPDDIAAAAAFLLGPEATFITGADLLVDGGVVAAIRASR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0243 | - | - | 100% (270) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_2869 | - | 3e-15 | 27.01% (274) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_4927 | - | 2e-14 | 26.48% (253) | dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0792 | - | 8e-15 | 26.88% (253) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1024 | - | 5e-27 | 30.94% (265) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0769 | - | 2e-14 | 26.48% (253) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-09 | 26.12% (268) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0691 | - | 7e-84 | 60.30% (267) | short chain dehydrogenase |
| M. avium 104 | MAV_5240 | - | 2e-29 | 31.94% (263) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6662 | - | 3e-29 | 32.33% (266) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_0784 | - | 4e-27 | 31.82% (264) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_4870 | - | 1e-141 | 95.54% (269) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5812 | - | 6e-27 | 30.94% (265) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0243|M.marinum_M MSRDVLTVIGVGGMGQAIARRLGSGKTVLLADNNADTLASVSETLAAEGH
MUL_4870|M.ulcerans_Agy99 MSRNVLTVIGVGGMGQAIARRLGSGKTVVLADNNADTLASVAESLAAEGH
MAB_0691|M.abscessus_ATCC_1997 MPDEVVVVIGVGGMGRVIARRQGIGKALLLADHNEQALQAVVDELKADGH
MAV_5240|M.avium_104 ---MSVITGGAGGMGVATAKVVGRDHTLVLCDVRQDRLTAATAALAELGM
Mvan_5812|M.vanbaalenii_PYR-1 MTAVSLITGGAGGMGLATAKVVGQDRAVVLCDVRQDRLDGAAAALKDLGV
MSMEG_6662|M.smegmatis_MC2_155 MRTVSVITGGAGGMGVATAKIVGKEHAVVLCDVRQDRLDTAATALAEVGI
TH_0784|M.thermoresistible__bu -------------MGQATARVVGREHAVVLCDVRQDRLDTAAAVLRDDGI
Mflv_1024|M.gilvum_PYR-GCK MSAVSLITGGAGGMGLATAKVVGRDHSVVLCDVRQERLDAAAAELAGLGI
Mb0792|M.bovis_AF2122/97 MFDSKVAIVTGAAQGIGQAYA----QALAREGAS-----VVVADINADG-
Rv0769|M.tuberculosis_H37Rv MFDSKVAIVTGAAQGIGQAYA----QALAREGAS-----VVVADINADG-
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVS----RSILVTGGNRGIGLAVARRLVADGH
* ::: . . : *
MMAR_0243|M.marinum_M DVKSRGVDVCAAESVHDLAQYAATLGAVTQLAHTAGLSPAQASAQAILAV
MUL_4870|M.ulcerans_Agy99 DVRSRGVDVCAAESVHDLAQYAATLGAVTQLAHTAGLSPTQASAQAILAV
MAB_0691|M.abscessus_ATCC_1997 NVIGQRVDVSSRASVSGLAQAAAGLGRVAQVAHTAGLSPAQSPTAAILAV
MAV_5240|M.avium_104 TPTAVNCDVTDRRAVAQLFDTAAGLGTVVSVIHTAGVSPSMGPADYVMRT
Mvan_5812|M.vanbaalenii_PYR-1 AVTAVNCDVTDRRAVDALFETVSRLGTLVSVIHTAGVSPSMGDAEYVMRT
MSMEG_6662|M.smegmatis_MC2_155 TPTVVKCDVTDRHAVNRLFATTAGLGTLASVIHTAGVSPSMGDAEYVIRT
TH_0784|M.thermoresistible__bu TATPVHCDVTDPQAVDRLFKETAGIGELASVIHTAGVSPSMGSAEYVMRT
Mflv_1024|M.gilvum_PYR-GCK SATTVHCDVTDRDAVGRLFDGAAVAGTLASVIHTAGVSPSMGDAEYVMRT
Mb0792|M.bovis_AF2122/97 AAAVAKQIVADGGTVIHVPVDVSDEDSAKAMVDRA--VGAFGGIDYLVNN
Rv0769|M.tuberculosis_H37Rv AAAVAKQIVADGGTAIHVPVDVSDEDSAKAMVDRA--VGAFGGIDYLVNN
MLBr_01807|M.leprae_Br4923 RVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAV--EEHQGPVEVLVAN
: .: . . . . ::
MMAR_0243|M.marinum_M DLLGVALVLQEFGAVIAPGGAGVIIASMAGHLLPPPSAEQ------EREL
MUL_4870|M.ulcerans_Agy99 DLVAVALVLQEFGAVIAPGGAGVIIASMAGHLLPPPSAEQ------EHDL
MAB_0691|M.abscessus_ATCC_1997 DLVGVALVVEEFGKIVASGGAGVVIASMAGHMPYELTAEQ------EQEL
MAV_5240|M.avium_104 NAIGTLNVNEAFYAVAGDGSVIVNVASMAAHMLPAEIVPTAQFPLALSDA
Mvan_5812|M.vanbaalenii_PYR-1 NALGTLNVDEAFYGAATDGAAIVNVASMAAYLLPAELIPTSAFPLALQDT
MSMEG_6662|M.smegmatis_MC2_155 NAIGTATINEAFYAAAPRGSAIVNVASMAAHLLPEEMIPTGLFPQAMQAP
TH_0784|M.thermoresistible__bu NAVGTVHVNEAFLRTAGAGAAIVNVASMAAHMLPAEMVRTNLFARALTDL
Mflv_1024|M.gilvum_PYR-GCK NALGTVNVGEQFFARAGEGAALVNVASMAAHILPAELIPTAVFPAALQDP
Mb0792|M.bovis_AF2122/97 AAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYK-------HMA
Rv0769|M.tuberculosis_H37Rv AAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYK-------HMA
MLBr_01807|M.leprae_Br4923 AGITSDM---LIMRMSEEQFQKVIDVNLTGVFRVAKLASR-------NMI
: : . .. . :
MMAR_0243|M.marinum_M AHRPPGQLLELDFVGSIVEPA-FAYPFAKQANSIRVRAASRQWGQREARV
MUL_4870|M.ulcerans_Agy99 AHRPPGQLLELDFVGSIVEPA-FAYPFAKQANSIRVRAASRQWGQREARV
MAB_0691|M.abscessus_ATCC_1997 GTTHAEDLLSLPYVRDIEHPA-VAYQVSKRANHIRVRFAARQWGTRGARI
MAV_5240|M.avium_104 DAFMDAMLAACEIAPEQARSG-LAYAVSKSFVKWYSQSQAERFNARGLRI
Mvan_5812|M.vanbaalenii_PYR-1 EAFMTEMLAACAIAPEEARSG-ISYAISKSFVRWYSSSQAERFNGRGLRI
MSMEG_6662|M.smegmatis_MC2_155 EVFLKDMLAACEIVPEEARSG-IAYALSKSFVRWYSSSQAERFTGRGLRI
TH_0784|M.thermoresistible__bu DGFLSEMLATCDAFPEEGRSG-IAYALSKSFVKWYSAAQAERFNARGLRI
Mflv_1024|M.gilvum_PYR-GCK DTFMAEMLTACEIAPEEARSG-IAYALSKSFVRWYSVAQAERFNGKGLRI
Mb0792|M.bovis_AF2122/97 KRGGGAIVNQSSTAAWLYSN---FYGLAKVGVNGLTQQLARELGGMKIRI
Rv0769|M.tuberculosis_H37Rv KRGGGAIVNQSSTAAWLYSN---FYGLAKVGVNGLTQQLARELGGMKIRI
MLBr_01807|M.leprae_Br4923 KQRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITA
: * :* :..
MMAR_0243|M.marinum_M NSISPGIISTPMGQQELASPVGDGMRAMIAMSGTGRIGTPDDIAAAAAFL
MUL_4870|M.ulcerans_Agy99 NSISPDIISTPMGQQELASPVGDGMRAMIAMSGTGRIGTPDDIAAAAAFL
MAB_0691|M.abscessus_ATCC_1997 NSISPGVVSTPMGHQELASETGAITKAMVDGSASRRIGTSDDIAAAAAFL
MAV_5240|M.avium_104 VSVSPGSIDTEMGRLEENAGAG----AMVADAAVPRWGKPEEMAELLAFC
Mvan_5812|M.vanbaalenii_PYR-1 VSVSPGSVDTEMGRLEEQAGAG----AMVADAAVPRWGKPEEMAELLAFC
MSMEG_6662|M.smegmatis_MC2_155 VSVSPGSVDTEMGRLEEKAGAG----ALVADAAVPRWGTPEEMAELFAFC
TH_0784|M.thermoresistible__bu VSVSPGSIDTEMGRLEEQAGAG----AMVADAAVPRWGTPEEMAELLAFC
Mflv_1024|M.gilvum_PYR-GCK LSVSPGSIDTEMGRLEEQAGAG----AMVADAAVPRWGTAEEMADLLAFC
Mb0792|M.bovis_AF2122/97 NAIAPGPIDTEATRTVTPAELVK---NMVQTIPLSRMGTPEDLVGMCLFL
Rv0769|M.tuberculosis_H37Rv NAIAPGPIDTEATRTVTPAELVK---NMVQTIPLSRMGTPEDLVGMCLFL
MLBr_01807|M.leprae_Br4923 NVVAPGFIDTEMTRAMD-SKYQE---AALQAIPLGRIGAVEEIAGAVSFL
::*. :.* : : : * * :::. *
MMAR_0243|M.marinum_M LGPEATFITGADLLVDGGVVAAIRASR---------
MUL_4870|M.ulcerans_Agy99 LGPEATFITGADLLVDGGVVAAIRANG---------
MAB_0691|M.abscessus_ATCC_1997 LGPESSYVTGTDLLVDGGVIAAVRSGQLFN------
MAV_5240|M.avium_104 ASDKAGYLTGTDILNDGGVIASMTERARVTAAG---
Mvan_5812|M.vanbaalenii_PYR-1 AGDKAGYLTGTDILNDGGVVASMTERARLAAASSS-
MSMEG_6662|M.smegmatis_MC2_155 ASDRAGYLTGTDILNDGGVVASMRERARVAAEQQQQ
TH_0784|M.thermoresistible__bu ASAKASYLTGTDILNDGGVIASMTERARAAAETQ--
Mflv_1024|M.gilvum_PYR-GCK ASRKAGYLTGTDILNDGGVIASMTERTRLASQ----
Mb0792|M.bovis_AF2122/97 LSDSASWITGQIFNVDGGQIIRS-------------
Rv0769|M.tuberculosis_H37Rv LSDSASWITGQIFNVDGGQIIRS-------------
MLBr_01807|M.leprae_Br4923 ASEDAGYISGAVIPVDGGLGMGH-------------
. : :::* : ***