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MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSA TGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDL GLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPTYAGRFYTLDGATCDPPPVQRPHPPL WIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVR IREEFASIPEPGLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | - | 100% (347) | hypothetical protein Mb0815c |
| M. bovis AF2122 / 97 | Mb1886c | - | 4e-30 | 30.23% (301) | oxidoreductase |
| M. bovis AF2122 / 97 | Mb3106c | - | 4e-22 | 31.20% (250) | hypothetical protein Mb3106c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0268 | - | 4e-41 | 30.15% (325) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 0.0 | 100.00% (347) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00269 | - | 5e-17 | 22.99% (348) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4277 | - | 6e-47 | 33.64% (324) | luciferase-like monooxygenase superfamily protein |
| M. marinum M | MMAR_2559 | - | 1e-129 | 64.76% (332) | oxidoreductase |
| M. avium 104 | MAV_0169 | - | 6e-38 | 35.27% (275) | hypothetical protein MAV_0169 |
| M. smegmatis MC2 155 | MSMEG_3301 | - | 1e-39 | 36.40% (272) | hypothetical protein MSMEG_3301 |
| M. thermoresistible (build 8) | TH_2824 | - | 1e-43 | 30.89% (327) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_3202 | - | 1e-128 | 64.46% (332) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0629 | - | 4e-44 | 31.38% (325) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0815c|M.bovis_AF2122/97 MNAKDD-------PHFGLMLAATVNGLAVGSYREMVVVSQTAEEYG-FDS
Rv0791c|M.tuberculosis_H37Rv MNAKDD-------PHFGLMLAATVNGLAVGSYREMVVVSQTAEEYG-FDS
MMAR_2559|M.marinum_M MHENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVSTLAESYG-FDS
MUL_3202|M.ulcerans_Agy99 MHENTSNPPQHGGPQFGLILALMTQGLAISDYPDMVRVSTLAESYG-FDS
MAV_0169|M.avium_104 ------------------MRFAFKTSPQNTTWAQMLAVWQAADDIDVYES
MSMEG_3301|M.smegmatis_MC2_155 ------------------MRFAFKTSPQNTTWQDMLAVWQTADDIEVFES
Mflv_0268|M.gilvum_PYR-GCK --------MSSV------DFRVFVEPQQGASYADQLAVARTAEQAG-YSA
Mvan_0629|M.vanbaalenii_PYR-1 --------MSTVAATNTPDFRIFVEPQQGASYADQLAVARTAESAG-YSA
TH_2824|M.thermoresistible__bu -----------------MDFRVFVEPQQGGTYADQLAVARAAEDLG-YSA
MAB_4277|M.abscessus_ATCC_1997 -----------------MDFRVFVEPQQGATYSDQLRVAQAAEELG-FSA
MLBr_00269|M.leprae_Br4923 ---------------MAELRLGYKASAEQFAPRELVELGVAAEAHG-MDS
: : : *: .:
Mb0815c|M.bovis_AF2122/97 VWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLEC
Rv0791c|M.tuberculosis_H37Rv VWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLEC
MMAR_2559|M.marinum_M VWLCDHFLTLSPDDYVTQAGISGEHERRNGRDR-------PA-TMPLLEA
MUL_3202|M.ulcerans_Agy99 VWLCDHFLTLSPDDYVTQAGISGEHERRDGRDR-------PG-TMPLLEA
MAV_0169|M.avium_104 GWTFDHFYPIFSDS-----------------------------SGPCLEG
MSMEG_3301|M.smegmatis_MC2_155 GWTFDHFYPIVGDS-----------------------------SGPCLEG
Mflv_0268|M.gilvum_PYR-GCK FFRSDHYLAMAG-DGLPG----------------------------PTDS
Mvan_0629|M.vanbaalenii_PYR-1 FFRSDHYVAMAG-DGLPG----------------------------PTDS
TH_2824|M.thermoresistible__bu FFRSDHYLAMSG-DGLPG----------------------------PTDS
MAB_4277|M.abscessus_ATCC_1997 FFRSDHYLAMGGADGLPG----------------------------PTDA
MLBr_00269|M.leprae_Br4923 ATVSDHFQPWRHQGG------------------------------HASFS
**: .
Mb0815c|M.bovis_AF2122/97 WTALAALSRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVISQGRLDLG
Rv0791c|M.tuberculosis_H37Rv WTALAALSRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVISQGRLDLG
MMAR_2559|M.marinum_M WTALSALARDTTYIRLGTSVLCNSYRH-PAVLAKMAATLDIISEGRLDLG
MUL_3202|M.ulcerans_Agy99 WTALSALARDTTYIRLGTSVLCNSYRH-PAVLAKMAATLDIISEGRLDLG
MAV_0169|M.avium_104 WTTLTALAQATKRLRLGTLVTGIHYRH-PAVLANMAAAVDIISGGRLELG
MSMEG_3301|M.smegmatis_MC2_155 WTTLTALAQATSRLRLGTLVTGVHYRH-PAVLANMAAALDIISNGRLELG
Mflv_0268|M.gilvum_PYR-GCK WVTLAGLARETSSIRLGTMVTSATFRH-PGPLAISVAQVDEMSGGRVELG
Mvan_0629|M.vanbaalenii_PYR-1 WVTLAGIARETSTIRLGTMVTSATFRY-PGPLAISVAQVDEMSGGRVEFG
TH_2824|M.thermoresistible__bu WVTLAGIARETTSIRLGTLVTSATFRY-PGPLAISVAQVDEMSGGRVEFG
MAB_4277|M.abscessus_ATCC_1997 WVTLGAIARETTAIRLGTLVTSATFRH-PGPLAVTVAQVDEMSSGRVDFG
MLBr_00269|M.leprae_Br4923 LSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLG
: .:.. *. : *** * :*: *. :. * :. : .*: :*
Mb0815c|M.bovis_AF2122/97 LGAGWFRRESQ-AYGIPFPPVGDRVSALAESLQVIKAVWTEPNP---TYA
Rv0791c|M.tuberculosis_H37Rv LGAGWFRRESQ-AYGIPFPPVGDRVSALAESLQVIKAVWTEPNP---TYA
MMAR_2559|M.marinum_M LGAGWFEREFT-AYGIPFLPVGDRVTGLGEALEVITAIWTQPDP---VYS
MUL_3202|M.ulcerans_Agy99 LGAGWFEREFT-AYGIPFLPVGDRVTGLGEALEVITAIWTQPDP---VYS
MAV_0169|M.avium_104 IGAGWNEEESG-AYGIELGSIRERFDRFEEACAVLTSLLSQETT---DFD
MSMEG_3301|M.smegmatis_MC2_155 IGAGWNEEESG-AYGIELGSIKERLDRFEEATQVLIGLLSQDST---DFD
Mflv_0268|M.gilvum_PYR-GCK LGAGWFEAEHK-AYAIPFPPLGERFDRLTEQLEILTGLWTTPTGETFDYS
Mvan_0629|M.vanbaalenii_PYR-1 IGAGWFEAEHK-AYAIPFPPLGERFDRLTEQLEILTGLWTAAPGETFDYS
TH_2824|M.thermoresistible__bu LGSGWFEPEHQ-AYAIPFPPLGERFDRLTEQLEIITGLWTTPSGEKYDFT
MAB_4277|M.abscessus_ATCC_1997 LGAGWFSEEHE-AYAIPFPSLGERFDRLEEQLEILTGLWTTPTGDTYSYA
MLBr_00269|M.leprae_Br4923 VGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGDRV---DFD
:*:* * .* . :*. : * :: : :
Mb0815c|M.bovis_AF2122/97 GRFYTLDGATCDPPPVQRPHPPLWIGG--------------------EGD
Rv0791c|M.tuberculosis_H37Rv GRFYTLDGATCDPPPVQRPHPPLWIGG--------------------EGD
MMAR_2559|M.marinum_M GRFYTLDGAICDPPPVQTPHPPLWVGG--------------------EGD
MUL_3202|M.ulcerans_Agy99 GRFYTLDGAICDPPPVQTPHPPLWVGG--------------------EGD
MAV_0169|M.avium_104 GKFYQLKGARNEPKGPQRPHPPICIGG--------------------SGE
MSMEG_3301|M.smegmatis_MC2_155 GAFYTLKNARNEPKGPQRPHPPIVMGG--------------------SGE
Mflv_0268|M.gilvum_PYR-GCK GTHYSIADSPALPKPAQSPRPPIVIGG--------------------RGA
Mvan_0629|M.vanbaalenii_PYR-1 GRHYSIVDSPALPKPAQRPHPPIIIGG--------------------GGA
TH_2824|M.thermoresistible__bu GKHYTVVDSPGLPKPVQDPYPPIIIGG--------------------QGP
MAB_4277|M.abscessus_ATCC_1997 GKHYTVTDSPALPKPVQEPHPPIVIGG--------------------LGV
MLBr_00269|M.leprae_Br4923 GDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKGEE
* .* : .: : **
Mb0815c|M.bovis_AF2122/97 -RVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVT
Rv0791c|M.tuberculosis_H37Rv -RVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVT
MMAR_2559|M.marinum_M -RVHRIAARSAQGINVRWWSPQKVKQRKDFLAQACATAQRDPTTLRFSVT
MUL_3202|M.ulcerans_Agy99 -RVHRIAARSAQGINVRWWLPQKVKQRKDFLAQTCATAQRDPTTLRFSVT
MAV_0169|M.avium_104 KRTLRITARYAQHWNFVGGPPDVFAHKRDVLASHCADIGRDPKEILLSAH
MSMEG_3301|M.smegmatis_MC2_155 KRTLRITAKYADHWNFVLGTPEEFAHKRDVLWSHCADIGRDPKEITLSAH
Mflv_0268|M.gilvum_PYR-GCK KRTPALTARFADEFNIPFVPLDELTTQYARVAAAVEDAGRAKDSLTYSAA
Mvan_0629|M.vanbaalenii_PYR-1 KRTPALAARFADEFNIPFVPLDTLTEQYGRVAAAVEQAGRAKDSLIYSAA
TH_2824|M.thermoresistible__bu KRTPALAARFANEFNIPFVRLDALKAQFERVAAAVAEAGREPDSMIYSAA
MAB_4277|M.abscessus_ATCC_1997 KRTPALAARFATEFNLPFQPVDVITDQYARVAHAVEAAGRPADSMTYSAA
MLBr_00269|M.leprae_Br4923 LYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAP
. : . . : . : : .
Mb0815c|M.bovis_AF2122/97 LLLAPTQS-------GEEEVRIREEFASIPEPGLIVGTPDRCVERIREYQ
Rv0791c|M.tuberculosis_H37Rv LLLAPTQS-------GEEEVRIREEFASIPEPGLIVGTPDRCVERIREYQ
MMAR_2559|M.marinum_M ALLAPTDS-------AEQEAQIRTEFSAVPYDGLIVGPADRCIERINEYY
MUL_3202|M.ulcerans_Agy99 ALLAPTDS-------AEQEAQIRTEFSAVPYDGLIVGPADRCIERINEYY
MAV_0169|M.avium_104 LRLEPDLD-------YGKVIDDAAALAAEGLDLGIVYLPPPHDPAVLEP-
MSMEG_3301|M.smegmatis_MC2_155 VWHNAEHD-------HQKLLTEVAAFGEVGLDLAIIYLPPPLTPAILEP-
Mflv_0268|M.gilvum_PYR-GCK FVVCVGRDD---AEIARRAAAIGREVDEMRSNSPTVGTPAEVVDKLGPFL
Mvan_0629|M.vanbaalenii_PYR-1 FVLCVGRDE---TEIARRAAAIGREVDELRSNSPVVGTPGEVVDKLRPFL
TH_2824|M.thermoresistible__bu FVLCAGRDD---AEIARRAAAINREVDELRSNSPVVGTPAEIVDRLGPFI
MAB_4277|M.abscessus_ATCC_1997 FALCIGDTD---ADIARRAANIGREVEEITENSPLAGTPDAVAEKLSIYV
MLBr_00269|M.leprae_Br4923 LSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVARVGQYV
. . . :
Mb0815c|M.bovis_AF2122/97 DRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
Rv0791c|M.tuberculosis_H37Rv DRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
MMAR_2559|M.marinum_M ESGVDTFLFTIPDVARSDLIHTVGQEVLPAFD------
MUL_3202|M.ulcerans_Agy99 ESGVDTFLFTIPDVARSDLIHTVGQEVLPAFD------
MAV_0169|M.avium_104 ---------LAEAIRDSGLLRS----------------
MSMEG_3301|M.smegmatis_MC2_155 ---------LAAAITASGLLTTTKE-------------
Mflv_0268|M.gilvum_PYR-GCK EAGVERVYLQVLDMSDLEHVEFFAEQVIPQIH------
Mvan_0629|M.vanbaalenii_PYR-1 EAGVQRIYLQLLDMSDLDHVQFFAEQVIPRIG------
TH_2824|M.thermoresistible__bu EAGVQRVYLQLLDMSDLDHLELIATQVVPQLR------
MAB_4277|M.abscessus_ATCC_1997 DAGVQRVYVQLLDIRDLDHLEFFASTVIPQFS------
MLBr_00269|M.leprae_Br4923 TWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG---
: