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VSDRVTAAVERTLDDRQREATEEVERILAAAVRVMERAAPEPPRVSDIVAEAGSSNKAFYRYFAGKDDLI LAVMERGVAIVVSYLGHQMAKESRPDTKIARWIEGTLAQVADPHLISMSRAAAGQLSNWLATQREMLRPL RFLLTAPVTALGSSDVDRDVEAVYGCTVATMRRYVGSAERPGRDDIEHLVRFCLLGLGVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4386 | - | - | 100% (200) | hypothetical protein MUL_4386 |
| M. ulcerans Agy99 | MUL_3464 | - | 2e-09 | 30.43% (184) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_1879 | - | 6e-06 | 38.36% (73) | AsnC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3185c | - | 1e-05 | 24.81% (133) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2097 | - | 7e-09 | 35.63% (87) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3160c | - | 1e-05 | 24.81% (133) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1024 | - | 2e-05 | 30.86% (81) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5312 | - | 1e-106 | 97.50% (200) | hypothetical protein MMAR_5312 |
| M. avium 104 | MAV_0309 | - | 8e-90 | 82.67% (202) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2305 | - | 1e-05 | 30.34% (89) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3734 | - | 2e-11 | 24.38% (201) | PUTATIVE putative transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_4608 | - | 7e-08 | 32.58% (89) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4386|M.ulcerans_Agy99 -MSDRVTAAVERTLDDRQREATEEVERILAAAVRVMERAAPEPPRVSDIV
MMAR_5312|M.marinum_M -MSDRVTAAVERALDDRQREATEEVERILAAAVRVMERAAPEPPRVSDIV
MAV_0309|M.avium_104 MISDRVTAAVERALDDRQREATEEVERILAAAVRVMERVAPEPPRVSDIV
Mflv_2097|M.gilvum_PYR-GCK ----------------------------MEAAYRCLADPHAGPVSMAAIL
Mvan_4608|M.vanbaalenii_PYR-1 --------------MQPGPDHDGDRRRIIEAAYRCLAQPHAGPIPMTSIL
TH_3734|M.thermoresistible__bu ------------VAETRTVDRSSERQHIIDAAYRCLDRNSGSSASITEIL
Mb3185c|M.bovis_AF2122/97 -------------MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIA
Rv3160c|M.tuberculosis_H37Rv -------------MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIA
MAB_1024|M.abscessus_ATCC_1997 ----------------MSADPDPTGERILEAALQTMLSFGIRRATVDEIA
MSMEG_2305|M.smegmatis_MC2_155 -------MPDADKTTRKRADARRNEQALLEAAAAAFVAAG-VEVPVRDIA
: ** : *
MUL_4386|M.ulcerans_Agy99 AEAGSSNKAFYRYFAGKDDLILAVMERGVAIVVSYLGHQMAKES-RPDTK
MMAR_5312|M.marinum_M AEAGSSNKAFYRYFAGKDDLILAVMERGVAIVVSYLEHQMAKES-SPDTK
MAV_0309|M.avium_104 AEAGSSNKAFYRYFAGKDELILAVMERGVAIVVSYLEHQMAKEA-TPRGK
Mflv_2097|M.gilvum_PYR-GCK GTAGVSSRAFYRHFESKDDLFLALLEQECSAVVGQVDRVADAAQGSPADQ
Mvan_4608|M.vanbaalenii_PYR-1 RSAGLSSRAFYRHFLSKDDLFLALLRQECEAVIAQVDRIADAAVGSPADQ
TH_3734|M.thermoresistible__bu DEAGLGTRAFYRNFSTKHDLLLEMFRRDREAVQAQLREAVARAP-TPVEA
Mb3185c|M.bovis_AF2122/97 AAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFGHITAMPV-PAVVK
Rv3160c|M.tuberculosis_H37Rv AAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFGHITAMPV-PAVVK
MAB_1024|M.abscessus_ATCC_1997 RRAGVSHMTVYRRWSNKTDLVLAVLMREAQAIFTSVDAEIAALD-SPEEK
MSMEG_2305|M.smegmatis_MC2_155 ARAGVGMGTIYRHFPTRADLIIAVYRHQVDACADAGPQLLEQTT--PYAA
.* :.*: : : ::. : .
MUL_4386|M.ulcerans_Agy99 IARWIEGTLAQVADPHLISMSRAAAGQLSN---WLATQREMLRPLRFLLT
MMAR_5312|M.marinum_M IARWIEGTLAQVADPHLISMSRAAAGQLSN---WLATDREMLRPLRDLLT
MAV_0309|M.avium_104 IARWIEGTLAQVADPHLISMTRAAAGQMSAGTSWRAADQEMMRPLRELLV
Mflv_2097|M.gilvum_PYR-GCK LAAWIEAMFDIVVDPRQRLQLTVIDSEEVRTAKGYRQTRDRLHAARERGL
Mvan_4608|M.vanbaalenii_PYR-1 LADWIAAMFDIIVDPQQRLQLTVIDSDEVRAAKGYREMRERLHAERERSL
TH_3734|M.thermoresistible__bu LRSWMTHMFELVSNPRKRRRVATLYSEEMRRTPGYVRELELVTAADQASI
Mb3185c|M.bovis_AF2122/97 LHRWLTESLDHLHASPYVLVSILITPDLHQES--FVAERELVAEMER-AL
Rv3160c|M.tuberculosis_H37Rv LHRWLTESLDHLHASPYVLVSILITPDLHQES--FVAERELVAEMER-AL
MAB_1024|M.abscessus_ATCC_1997 LVAGFTGIYWHVHTHPLMRRAVETDPESVLPVMTSGAG-PALDMATTYLA
MSMEG_2305|M.smegmatis_MC2_155 LAKWVDQFVDFLVTKHG--LAAALHSDNARYQTLHTYFLDRLLPVCAQLL
: . : : :
MUL_4386|M.ulcerans_Agy99 APVTALGSSD-------VDRDVEAVY-GCTVATMRRYVGSAERPGRDDIE
MMAR_5312|M.marinum_M APVTALGSSD-------VDRDVEAVY-GCTVATMRRYVGSAERPGRDDIE
MAV_0309|M.avium_104 EPVAALGSSD-------VDRDVEAVF-SCTAATLRRYVGSAQQPAPDDIA
Mflv_2097|M.gilvum_PYR-GCK AEILRRGLRDGSFPLTEPEADAVAIN-AVVSRVLNTQTTDEPEARKKALV
Mvan_4608|M.vanbaalenii_PYR-1 AEILRRGRRDGSFPLAEPEIDAVAVN-ALVSRLLVRQTTDDPQARKQAEV
TH_3734|M.thermoresistible__bu AAILHRGKAEGIFTACTPEADARSIHAAFEAALLDRFHQKSTTDAADEVE
Mb3185c|M.bovis_AF2122/97 VGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEFAMT
Rv3160c|M.tuberculosis_H37Rv VGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEFAMT
MAB_1024|M.abscessus_ATCC_1997 GHVSQSAGDLVDDPYGIAEVFVRLTHSLILAPSPRRELATREDAQQYARR
MSMEG_2305|M.smegmatis_MC2_155 DAAVAS------------NEICSGVDPYVFMRAIGNLCIGAEDDPRYDAR
MUL_4386|M.ulcerans_Agy99 HLVR--FCLLGLGVS---------------
MMAR_5312|M.marinum_M HLVR--FCLLGLGVS---------------
MAV_0309|M.avium_104 HVVR--FCLRGLGVR---------------
Mflv_2097|M.gilvum_PYR-GCK AVLD--FALRAVGAAAR-------------
Mvan_4608|M.vanbaalenii_PYR-1 AVLD--FALRAVGAVPGGQDTRR-------
TH_3734|M.thermoresistible__bu HLLA--FFLRGLGVAT--------------
Mb3185c|M.bovis_AF2122/97 ALLSDPDRLAEIRAAADALEIQTAPPDRGL
Rv3160c|M.tuberculosis_H37Rv ALLSDPDRLAEIRAAADALEIQTAPPDRGL
MAB_1024|M.abscessus_ATCC_1997 YILPIAQALVPAASPAVR------------
MSMEG_2305|M.smegmatis_MC2_155 AMVA--VLINGLRRPSE-------------
:: :