For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MAERNRTDDAAVSKIAVEVVDRLSAQLAEATASIQGTLEREIVELRGDAQLLDLLHASVEGNVAAVLNAI HYDIPIERVESPTAALEYARRLAQRGVPVNALVRAYRLGHKEMLERIIDGVQEAGADPALSLDVFNRISE VTFNYIDWISQQVVAAYEAERDRWLENRSRVRNVRIAEILDGGDIDTDAMTRSIRYPLRKVHLALVLWFP DDATDGNEFERLERFLDELAEHLGTGNALFVAADRVTGWGWIPLRVNDAGLAERVRRFVAGHTDAPHVAL GQALPGVEGFRRAHRQARNAHRVGVAVGASAPAVVAVSDEGLSAAALMGADLPEAGAWVRETLGPLSTDS DNDAVLRETLRVFLREGGSYKAAAERLHLHYNSVKYRVARAVERRGRPIDDERLDVEMALLVCQWFGAVV LGPER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1582 | - | - | 100% (425) | hypothetical protein MMAR_1582 |
| M. marinum M | MMAR_1603 | - | e-116 | 50.72% (414) | hypothetical protein MMAR_1603 |
| M. marinum M | MMAR_1323 | - | e-112 | 50.36% (415) | hypothetical protein MMAR_1323 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1464 | - | 2e-51 | 33.76% (391) | hypothetical protein Mb1464 |
| M. gilvum PYR-GCK | Mflv_4621 | - | 1e-92 | 44.58% (397) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1429 | - | 2e-51 | 33.76% (391) | hypothetical protein Rv1429 |
| M. leprae Br4923 | MLBr_01052 | - | 2e-20 | 27.08% (336) | hypothetical protein MLBr_01052 |
| M. abscessus ATCC 19977 | MAB_2657c | - | 2e-18 | 28.45% (239) | hypothetical protein MAB_2657c |
| M. avium 104 | MAV_2195 | - | 1e-06 | 28.19% (188) | hypothetical protein MAV_2195 |
| M. smegmatis MC2 155 | MSMEG_4324 | - | 7e-08 | 33.10% (145) | hypothetical protein MSMEG_4324 |
| M. thermoresistible (build 8) | TH_2938 | - | 1e-120 | 56.17% (381) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3452 | - | 0.0 | 96.94% (425) | hypothetical protein MUL_3452 |
| M. vanbaalenii PYR-1 | Mvan_3753 | - | 3e-07 | 36.51% (126) | hypothetical protein Mvan_3753 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1582|M.marinum_M --------------MAERNRTDDAAVSKIAVEVVDRLSAQLAEATASIQG
MUL_3452|M.ulcerans_Agy99 --------------MAERNRTDDAVVGKIVVEVVYRLSAQLAEATASIQG
TH_2938|M.thermoresistible__bu ----------------------------------------VGYGPGSRQG
Mflv_4621|M.gilvum_PYR-GCK --------------MLDSSEVQDTPG-HAVHHLFRDLGDLVRELPESIHG
Mb1464|M.bovis_AF2122/97 ---------------------MAEAGGGPISVIARHMQLIRDDFISELFD
Rv1429|M.tuberculosis_H37Rv ---------------------MAEAGGGPISVIARHMQLIRDDFISELFD
MLBr_01052|M.leprae_Br4923 ----------------MARQHPSPRVRELIREGARIALNPTQEWIDQLDR
MAB_2657c|M.abscessus_ATCC_199 MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLARSGEVAGDLTA
MSMEG_4324|M.smegmatis_MC2_155 -------------MPDNRFVP-----PKSTVEVLEAVPDSLLRRLKQYSG
Mvan_3753|M.vanbaalenii_PYR-1 -------------MTDNRFIP-----PRSTVEVLENVPESTLRRLKQYSG
MAV_2195|M.avium_104 -------------MNDNPFAGPFAKHPRSPLETLDTVPESVLRRLKQYSG
.
MMAR_1582|M.marinum_M TLEREI--VELRGDAQLLDLLHASVEGNVAAVLNAIHYDIPIERVESP-T
MUL_3452|M.ulcerans_Agy99 TLEREI--VELRGDVQLLDLLHASVEGNVAAVLNAIHYDIPIERVESP-T
TH_2938|M.thermoresistible__bu -----------SGCRQLLELLRDSVEGNIDTIFSAIQHDIPIEEVAPP-T
Mflv_4621|M.gilvum_PYR-GCK LLIEQV--AELAADQQLKELLSDTVAANVDTWFSVVRHSIPFDRMESP-T
Mb1464|M.bovis_AF2122/97 KMKAEI--RGLDYDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP-A
Rv1429|M.tuberculosis_H37Rv KMKAEI--RGLDYDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP-A
MLBr_01052|M.leprae_Br4923 ATFAAN--PAIANDPVLAKVVRRASRAHLVHWATANLRDPGAPVPAHLGP
MAB_2657c|M.abscessus_ATCC_199 ASLEDPRYRTIADDPVIAEVDARLTVSNLKHWLTSNISEPGHRVRPATGS
MSMEG_4324|M.smegmatis_MC2_155 RLATEAVHAMEQRLPFFAELDASQRASVQLVVQTAVVNFVEWMRNPESNV
Mvan_3753|M.vanbaalenii_PYR-1 RLATQAVHAMEERLPFFAELDASQRASVQLVVQTAVVNFAEWMRDPRSNV
MAV_2195|M.avium_104 RLATEAVSVMQDRLPFFADLEASQRASVSLVVQTAVVNFAEWMQDPKSNV
: .:
MMAR_1582|M.marinum_M AALEYARRLAQRGVPVNALVRAYRLGHKEMLERIIDGVQEAGADPALSLD
MUL_3452|M.ulcerans_Agy99 AALEYARRLAQRGVPVNALVRAYRLGHKEMLERIIDGVQEAGADPALSLD
TH_2938|M.thermoresistible__bu AALEYARRLARHGVEPHALLRAYRLGQQKLLDIVLHEIRSLDWEREVSLE
Mflv_4621|M.gilvum_PYR-GCK AALEHARRMAQREVPVNALLRAYRLGHQYGLNLIIAGLRSADLPPEEKLA
Mb1464|M.bovis_AF2122/97 AALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVS--LLEPADRVS
Rv1429|M.tuberculosis_H37Rv AALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVS--LLEPADRVS
MLBr_01052|M.leprae_Br4923 EPLTMARDLVRRGRDVLALD-IYRVGQYTAWRRWMEIAFTLTSDPQELRE
MAB_2657c|M.abscessus_ATCC_199 AMRTYARDVVLRGLTTDDIQ-SWRAVQRVGWKWWLAACFQVTDDKEQLCE
MSMEG_4324|M.smegmatis_MC2_155 GYTAQAFEVVPQDLRRRVALRQSVEMVRTSMEFFEEAVPLLARSEEQ---
Mvan_3753|M.vanbaalenii_PYR-1 SYTAQAFEVVPQDLRRRIALRQSVEMVRVTMEFFEEVVPLLARSEDQ---
MAV_2195|M.avium_104 RHTAQAFELVPQDLARRIALRHSVEMVRVTMEFFEEVVPLLARSEEQ---
* . :
MMAR_1582|M.marinum_M VFNRISEVTFNYIDWISQQVVAAYEAERDRWLENRSRVRNVRIAEILDGG
MUL_3452|M.ulcerans_Agy99 VFNRISEVTFNYIDWISQQVVAAYEAERDRWLENRSRVRNVRIAEILDGG
TH_2938|M.thermoresistible__bu FVVGVTNATFGYIDGISQRVVEVYQQERERWLENRNSLRAMRVRELLDGG
Mflv_4621|M.gilvum_PYR-GCK LIEHITRVSFRYIDWMSEQVLETYQTERAEWDERRRSLRAQAIRDILNGR
Mb1464|M.bovis_AF2122/97 TIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWVSELLADT
Rv1429|M.tuberculosis_H37Rv TIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWVSELLADT
MLBr_01052|M.leprae_Br4923 ILNVSAQSINEYVAATLEAIATHMQLERDELTRSTHAERLEVVDLILEGA
MAB_2657c|M.abscessus_ATCC_199 LIEVTSNSLTTFVDDSIAELAEHVRRVREELAGGSQLQRYATVELLLQGA
MSMEG_4324|M.smegmatis_MC2_155 -LTALTAGILRYSRDLAFAAASAYADQAEARGAWDIRMEANIVDAVVRGD
Mvan_3753|M.vanbaalenii_PYR-1 -LAAMTAGILRYSRDLAFAAATAYADQAEARGAWDTRMEANLVDAVVRGG
MAV_2195|M.avium_104 -LTALTVGVLKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGD
. . : :: .
MMAR_1582|M.marinum_M DIDTDAMTRSIRYPLRKVHLALVLWFPDDA-TDGNEFERLER---FLDEL
MUL_3452|M.ulcerans_Agy99 DIDTDAMTKSIRYPLRKVHLALVLWFPDDA-TDGNEFERLER---FLDEL
TH_2938|M.thermoresistible__bu EVDVDTASATVGYPLRRTHLAVCVWTPDGS-AGDNELDRLQR---YVRGL
Mflv_4621|M.gilvum_PYR-GCK DVDLTEASSAMRYFLGATHVALMVWLDRDAGADTDEFIAMER---FMQHA
Mb1464|M.bovis_AF2122/97 PVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVRCLLAGEL
Rv1429|M.tuberculosis_H37Rv PVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVRCLLAGEL
MLBr_01052|M.leprae_Br4923 PVTQERAEARLGYRLGLTHTAAVIWSDDLDGDHGYLDQAAEA--------
MAB_2657c|M.abscessus_ATCC_199 DIAPARAEAQLGYALTGSHIGAVVWVDSEK-EIAALERASEQ--------
MSMEG_4324|M.smegmatis_MC2_155 TGPELQSQAAALNWDATAPATVIVGLPRADR--------IEMAR------
Mvan_3753|M.vanbaalenii_PYR-1 TRPELQSQAAALNWDATAPATVIVGMPRPDR--------AEFAG------
MAV_2195|M.avium_104 TGPELLSRAAALNWDTTAPATVVVGTPAPGRDGSTGPGDSERAS------
: :
MMAR_1582|M.marinum_M AEHLGT-GNALFVAADRVTGWGWIPLRVNDA-GLAERVRRFVAGHTDAPH
MUL_3452|M.ulcerans_Agy99 AEHLGT-GNALFVAADRITGWGWIPLRANDA-GLTGRVRRFVAGHTDAPH
TH_2938|M.thermoresistible__bu AEALGAPGDSLFIALDRLTGCGWIPLPGDAATGAVAGVRRYAAEHPDGPH
Mflv_4621|M.gilvum_PYR-GCK VSATGA-KQSVYFSIDRLVGCAWMTVHRPSD--YLSQLRDFVRAQPDGPR
Mb1464|M.bovis_AF2122/97 GPELGPVANSLMVPTDEREARLWFSPAPTRA-FAPSRIRAAFESAGIRAR
Rv1429|M.tuberculosis_H37Rv GPELGPVANSLMVPTDEREARLWFSPAPTRA-FAPSRIRAAFESAGIRAR
MLBr_01052|M.leprae_Br4923 FSHVVESTQQLIVVASAATRWVWLADALALD---VPEVQKALLNLS-KAR
MAB_2657c|M.abscessus_ATCC_199 VMRACGADRRLTVVAGTVALWLWIPAKTTPT---VAVLMDSLGRRS-GVR
MSMEG_4324|M.smegmatis_MC2_155 -DDVHAVVRRNDRAALSDVHGTWLVTIVSGPLSATDRFLADLMSVFADGP
Mvan_3753|M.vanbaalenii_PYR-1 -DDVHEVADRNGRTALSDVHGTWLVAIISGGLSPTDRFLSELMTVFADGP
MAV_2195|M.avium_104 -QHVRDIAAQHGRAALTDVHGTWLVAIVSGQLSPTDKFLGDLLEAFSDGP
*: .
MMAR_1582|M.marinum_M VALGQALPGVEGFRRAHRQARNAHRVGVAV-GASAPAVVAVSDEGLSAAA
MUL_3452|M.ulcerans_Agy99 VALGQALPGVEGFRRAHRQARNAHRVGVAV-GASAPAVMAVSDEGLSAAA
TH_2938|M.thermoresistible__bu LALGDPLPGLDGFRRSYRQALRTRAVAVAA-GASAPRVTAAADPGLSAAA
Mflv_4621|M.gilvum_PYR-GCK LSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARDPGVALAS
Mb1464|M.bovis_AF2122/97 LACGRVGDGLRGFRASLKQAERVKALALAG--GARPGGRVMFYDDVAPVA
Rv1429|M.tuberculosis_H37Rv LACGRVGDGLRGFRASLKQAERVKALALAG--GARPGGRVMFYDDVAPVA
MLBr_01052|M.leprae_Br4923 VAIGTSSAGIEGFRRSHLEALTAQRTLARL----KSHQQVAFFADVQLVS
MAB_2657c|M.abscessus_ATCC_199 VALGRAATGMAGFRRTHMDAAAAQRLLARL----GSPLSVVRYEDVHLMD
MSMEG_4324|M.smegmatis_MC2_155 VVIGPTTPTLTAAHRSATEAISGMNAVAGW----PSAPRPVSARELLPER
Mvan_3753|M.vanbaalenii_PYR-1 VVIGPTAPTLGAAHRSATEAIAGMNAVAGW----AGAPRPVSARELLPER
MAV_2195|M.avium_104 VVVGPTAPMLTAAYHSASEAISGMNAVGGW----RGAPRPVLARELLPER
: * : . : :* :
MMAR_1582|M.marinum_M LMGADLPEAGAWVRETLGPLSTDSDNDAVLRETLRVFLREGGSYKAAAER
MUL_3452|M.ulcerans_Agy99 LMGADLPDAGAWVRETLGPLSTDSDNDAVLRETLRVFLREGGSYKAAAER
TH_2938|M.thermoresistible__bu LLTGDLAEARTWVQEVLGPLSADTKNDARLRETLGVFLRHGSSYTAAADE
Mflv_4621|M.gilvum_PYR-GCK MLMTDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVFLRAGSSFKAAANE
Mb1464|M.bovis_AF2122/97 LLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRSYVATADA
Rv1429|M.tuberculosis_H37Rv LLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRSYVATADA
MLBr_01052|M.leprae_Br4923 LITQNPEDAKEFITSTLGDFESAS---PALQQTLLTFINEQCNASRAAKR
MAB_2657c|M.abscessus_ATCC_199 LLSADPASADQFVTDVLGEFQSAS---PVLHQTVLTYVEEALNRTSTAER
MSMEG_4324|M.smegmatis_MC2_155 ALLGDADAVTALETEVMRPLADAG---PALTETLDAFLDSGGAIEACARK
Mvan_3753|M.vanbaalenii_PYR-1 ALLGDATAGAALEAEVMRPLSDAG---PALMETLDAYLDSGGAIEACARK
MAV_2195|M.avium_104 ALMGDASAIVALHTDVMGPLADAG---PTLIETLDAFLDSGGAIEACARK
: : ..: : * :*: :: *
MMAR_1582|M.marinum_M LHLHYNSVKYRVARAVERRGRPIDD--ERLDVEMALLVCQWFGAVVLGPE
MUL_3452|M.ulcerans_Agy99 LHLHYNSVKYRVARAVERRGRPIDD--ERLDVEMALLVCQWFGAVVPGPE
TH_2938|M.thermoresistible__bu LNLHFNTVKYRVQRAVERRGRPIVP--DRLDVELALLICQWFGAAVLRPQ
Mflv_4621|M.gilvum_PYR-GCK LQIHANTVKYRVNRALERRGRPIAA--ERLDVEVALLMCYWLGEVALNPT
Mb1464|M.bovis_AF2122/97 MILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAK
Rv1429|M.tuberculosis_H37Rv MILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAK
MLBr_01052|M.leprae_Br4923 LFTHRNTLLRRIESAEKLLPRPLDH--TSVHIAVALEALQWRGDQTNTSG
MAB_2657c|M.abscessus_ATCC_199 LYTHRNTIDRRLARVDELLPKPFAR--NPIEVAAALTLLRVRAGR-----
MSMEG_4324|M.smegmatis_MC2_155 LFVHPNTVRYRLRRIADFTGRDPAVPRDAYVLRVASTVGRLSKHAYRAST
Mvan_3753|M.vanbaalenii_PYR-1 LFVHPNTVRYRLKRIADFTGRDPTVPRDAYVLRVASSVGRLARQAHLSAA
MAV_2195|M.avium_104 LFVHPNTVRYRLKRITDFTGRDPMQPRDAYVLRVAATVGQLNYPTHPPSA
: * *:: *: . : : *
MMAR_1582|M.marinum_M R---------------------
MUL_3452|M.ulcerans_Agy99 R---------------------
TH_2938|M.thermoresistible__bu R---------------------
Mflv_4621|M.gilvum_PYR-GCK QALGRS----------------
Mb1464|M.bovis_AF2122/97 Q---------------------
Rv1429|M.tuberculosis_H37Rv Q---------------------
MLBr_01052|M.leprae_Br4923 PRAGRNDGVPA-----------
MAB_2657c|M.abscessus_ATCC_199 ----------------------
MSMEG_4324|M.smegmatis_MC2_155 INSAVSVVPTIRPATSAGSRGT
Mvan_3753|M.vanbaalenii_PYR-1 PAAASAQAIGVASVTSPENLGT
MAV_2195|M.avium_104 AGAAMPAVPLPVNGAARGQSGG