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VRILLSGASISGSVLAFWLSRYGFDVTVVERAPQLRKAGGHAVDLFRPSMEISAKMGVLSKIEALATGTE ILTWYREGARRPVRVNLAKIFGATSDQHVEIMRDDLSEIYYEASRHDTEYLFGDSITAISPDGRVSFEQA APRCFDIVVGADGLHSNVRRLVFGEDAGHTQFLGGYLAVVSVPKGLAHDGEMVGHVGPGRMAAFYTAAPL DDAHLLFLFRTQEELRYHYRDVLRQKELLREAIAGIHPQVDLWLEELDRTPAFYFDSITQLQLDTWSRGR VTLVGDAGYCPGPAVGGSTSLSVLGACILAGEPAQAGGDYARAFAAYEREMADPVSRSHTFASGVAVSLI PRSKAGVWALTHGAQLVSMLPGGLTKAVAKLNTKGVRLYDSMRFKEYAPPRPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0294 | - | - | 100% (403) | membrane-associated oxidoreductase |
| M. ulcerans Agy99 | MUL_4482 | - | 1e-57 | 39.58% (336) | hypothetical protein MUL_4482 |
| M. ulcerans Agy99 | MUL_1770 | - | 1e-50 | 37.57% (338) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 4e-47 | 35.12% (336) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 2e-08 | 26.32% (342) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1260 | - | 6e-63 | 40.86% (350) | hypothetical protein Rv1260 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2678 | - | 1e-115 | 52.12% (401) | hypothetical protein MAB_2678 |
| M. marinum M | MMAR_4675 | - | 0.0 | 95.53% (403) | membrane-associated oxidoreductase |
| M. avium 104 | MAV_0984 | - | 1e-160 | 70.35% (398) | hypothetical protein MAV_0984 |
| M. smegmatis MC2 155 | MSMEG_5719 | - | 1e-137 | 61.96% (397) | oxidoreductase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 5e-15 | 28.57% (371) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0294|M.ulcerans_Agy99 -MR-ILLSGASISGSVLAFWLSRYGFDVTVVERAPQLRKAGGHAVDLFRP
MMAR_4675|M.marinum_M -MR-ILISGASISGPVLAYWLSRYGFDVTVVERAPQLRKAGGHAVDLFRP
MAV_0984|M.avium_104 -MR-ILISGASIAGPVLAYWLTRYGFEVTVVERAPTLRKTGGHAVDLFRP
MSMEG_5719|M.smegmatis_MC2_155 -MK-VLISGASIAGPVLAYWLSRHGFEVTVVERSPVLRKTGGHAVDLFRP
MAB_2678|M.abscessus_ATCC_1997 -MR-VLISGASIAGPVLAFWLAHYGFEVTVIERSPAPRKSGGHAVDLFKP
Rv1260|M.tuberculosis_H37Rv -MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLR-PGGQAIDVRGP
Mb0590c|M.bovis_AF2122/97 -MK-VAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFWGV
Mflv_2621|M.gilvum_PYR-GCK MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG--AGSGISLWPN
Mvan_3960|M.vanbaalenii_PYR-1 MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLT--SGAGISIWPN
: **.::* . * * : *. :::*: . .* :..
MUL_0294|M.ulcerans_Agy99 SMEISAKMGVLSKIEALATGTEILTWY-REGARRPVRVNLAKIFGATSDQ
MMAR_4675|M.marinum_M SMEISAKMGVLSKIEALATGTETLTWY-REGAQRPVRVNLAKIFSATSDH
MAV_0984|M.avium_104 AMEISAKMGVLPRIEDLATGTTRLTLY-REGRPQPSRIDLTKIYAASSDR
MSMEG_5719|M.smegmatis_MC2_155 AMEISERMGVLPEIEAHATGTTSMVVH-RPGTSRPARLDYLKVVGVISDR
MAB_2678|M.abscessus_ATCC_1997 AMDIIEMMGILDHVEAQSAGTEVLSIH-REG-KRLIDLPEVLIFSAVSER
Rv1260|M.tuberculosis_H37Rv ALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTESTPTGGPVNSP
Mb0590c|M.bovis_AF2122/97 GYQVAKRMGITDQIAAAGYHMEHVRSVGPTG-KVKADLGVDVFRRMVGDD
Mflv_2621|M.gilvum_PYR-GCK ALAALDQIGLGDSVRDAGGRVTAGAIRWRDG-TWVRRPSVRRIVDALGEP
Mvan_3960|M.vanbaalenii_PYR-1 ALAALDQIGLGDNVRQAGGRVTAGAIRWRDG-TWLRRPSAQRIVHALGEP
. :*: * ..
MUL_0294|M.ulcerans_Agy99 HVEIMRDDLSEIYYEASRHDTEYLFGDSITAISPDGR---VSFEQAAPRC
MMAR_4675|M.marinum_M HVEIMRDDLSEIYYEASRNDAEYLFGDSITAISPDGR---VSFEHAAPRC
MAV_0984|M.avium_104 HVEIMRDDLSEVYYDAARDDVEYLFGDSITAIEPDGT---VTFEHCAPRT
MSMEG_5719|M.smegmatis_MC2_155 HIEIMRDDLSEIYFRAGRDDVEYLFGDTITSISPDGD---VTFEHHPPRR
MAB_2678|M.abscessus_ATCC_1997 HVEIMRDDLSEILYGASAPSAEYIFGDSITALTDDGAGVRVAFDRASDRR
Rv1260|M.tuberculosis_H37Rv DIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVTFERAAARE
Mb0590c|M.bovis_AF2122/97 FTSLPRGDLAAAIYTTIEDQVETIFDDSIATIDEHRDGVRLTFERTAPRD
Mflv_2621|M.gilvum_PYR-GCK LVVVRRSRLTDILREALP-AGTVRTGLAATRVSVGASSVRITLSDGEVRE
Mvan_3960|M.vanbaalenii_PYR-1 LVVVRRSALTEILLDALP-PDTVQTGLSATALSIAAATARVTLSDGRTRE
: *. * : . : : : :::. *
MUL_0294|M.ulcerans_Agy99 FDIVVGADGLHSNVRRLVFGEDAGHTQFLGGYLAVVSVPKGLAHDGEMVG
MMAR_4675|M.marinum_M FDIVVGADGLHSNVRRLVFGEDAGHTQFLGGYLAVVSVPKGLAHDGEMVG
MAV_0984|M.avium_104 FDVVVGADGLHSNVRRLTFGDEAGLTRFLGGYLSVVSAPKTLVGPGEMVG
MSMEG_5719|M.smegmatis_MC2_155 FDVVVGADGLHSGVRRLVFGDNVSEN-FLAGYLSVVSVPKSLARDGEMTS
MAB_2678|M.abscessus_ATCC_1997 FDLVIGADGLHSHVRGLVFGPESGYSHWLGQYLAVASIPNYLDLSDRALM
Rv1260|M.tuberculosis_H37Rv FDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDYWQTW
Mb0590c|M.bovis_AF2122/97 FDLVIGADGLHSNVRRLVFGPERDFEHYLGCKVAACVVDGYRPRD--ERS
Mflv_2621|M.gilvum_PYR-GCK SDAVVGADGVNSVLARTLNGPLRTRYVGYTAWRGIAAHP--------LDP
Mvan_3960|M.vanbaalenii_PYR-1 ADAVVGADGVNSMVARALNGPLPSRYVGYTAWRGVAAYR--------LDP
* *:****::* : * .
MUL_0294|M.ulcerans_Agy99 HVGPGRMAAFYTAAPLDDAHLLFLFRTQEELRYHYRDVLRQKELLREAIA
MMAR_4675|M.marinum_M HVGPGRMAAVYTAAPLDDARLLFLFRTQEELQYHYRDVLRQKELLREAIA
MAV_0984|M.avium_104 HVGVGRFAGIYTADHLDDARAVFLFRSAAELAYDHRDTARQKELLREAFA
MSMEG_5719|M.smegmatis_MC2_155 FLKPGHMAAVYTADHLEDARAVFIFRPSRPLDYDHRDVERQKAQLRAAFE
MAB_2678|M.abscessus_ATCC_1997 YPQVDKIAGMYSAAQLSDARAFFLFRTPEPLDYHHRDVGRQKALLGEVYA
Rv1260|M.tuberculosis_H37Rv HYGDSTMAGVYSARNNTEARAALAFMDT-ELRIDYRDTEAQFAELQRRMA
Mb0590c|M.bovis_AF2122/97 YVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPG---VAPKDELRDQFG
Mflv_2621|M.gilvum_PYR-GCK ELGGETLGPGTQVGHVPLGPDHTYWFATERTAEGGSAPGGEHAYLTAKVA
Mvan_3960|M.vanbaalenii_PYR-1 ALAGETMSAGTEVGHVPLGPDHTYWFATERTREGSRSAGGEHAYLTAKLA
. : *
MUL_0294|M.ulcerans_Agy99 GIHPQVDLWLEELDRTPAFYFDSITQLQLDTWSRGRVTLVGDAGYCPGPA
MMAR_4675|M.marinum_M GMHPQVDLWLEELDRTPAFYFDSITQLQLDTWSRGRVTLVGDAGYCPGPA
MAV_0984|M.avium_104 GMHDEVDGWLAETERTPTFYFDSITQLRTDRWSRRRVTLVGDAGYCPGPA
MSMEG_5719|M.smegmatis_MC2_155 HIAPEVDRWLDEVPRTPAFYFDAITQLEMTTWSRGRVTLVGDAGYCPGPA
MAB_2678|M.abscessus_ATCC_1997 DVGWELPRMLAEVDATDTFYMDSITQLRMDTWSKGRITLVGDAGYCPGPA
Rv1260|M.tuberculosis_H37Rv EDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVALVGDAGYCCSPL
Mb0590c|M.bovis_AF2122/97 DVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISLL
Mflv_2621|M.gilvum_PYR-GCK DWADPIPRLVATTDPGDLLRNDLYDRARAARWSDGRAVLIGDAAHPMRPH
Mvan_3960|M.vanbaalenii_PYR-1 GWADPIPALLASTDPADVLRNDLYDRAQPRDWSRGPAVIVGDAAHPMRPH
: : * : ** ::***.
MUL_0294|M.ulcerans_Agy99 VGGSTSLSVLGACILAGEPAQAGGDYARAFAAYEREMADPVSRSHTFASG
MMAR_4675|M.marinum_M VGGSTSLSVLGAYILAGELAQAGGDYARAFAAYEREMADPVSRSRAFASG
MAV_0984|M.avium_104 VGGSTSLAVLGAYVLAGELARADGDHLRAFAAYELQMRESVRRSRSFARA
MSMEG_5719|M.smegmatis_MC2_155 VGGSTSLAVYGAYVLAAEMVRAGEDYPAAFDAYERTMLAPVVGSRKLARF
MAB_2678|M.abscessus_ATCC_1997 VGGSTSLAVVGAYVLAGEIAAAAGDHARAYPAYEAALREYVEVSRKLALT
Rv1260|M.tuberculosis_H37Rv SGQGTSVALLGAYILAGELKAAGDDYQLGFANYHAEFHGFVERNQWLVSD
Mb0590c|M.bovis_AF2122/97 GGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAAK
Mflv_2621|M.gilvum_PYR-GCK LGQGGCQGIEDAAILA-RFLELADDVPTAFERFEAFRKPRVGMLVREAQT
Mvan_3960|M.vanbaalenii_PYR-1 LGQGGCQGLEDAAILA-RFVGLSPDLPAAFDRFGAFRRRRVRPLVRESAA
* . .: * :** . * .: : :
MUL_0294|M.ulcerans_Agy99 VAVSLIPRSKAGVWALTHGAQLVSMLPGGLTKAVAKLNTKG-VRLYDSMR
MMAR_4675|M.marinum_M VAVSLIPRSKAGVWALTHGAQLVSMLPGGLTKAVAKLNTKG-VRLYDSMR
MAV_0984|M.avium_104 AARGVIPGSRAGVWALTRGAQLVSAMPTSLARALAKLNTKG-VRMHDSMP
MSMEG_5719|M.smegmatis_MC2_155 NAKTVVPASGLGIRALVGVGQLISVLPVGLTRSLARLNDKG-VRLYDTMP
MAB_2678|M.abscessus_ATCC_1997 ASGTLVPKSRLGLCTLVHGARILGHLPSSLTRSLSRLVAARRINIHDTFA
Rv1260|M.tuberculosis_H37Rv N----IPGG-------------------------APIPQEEFERIVHSIT
Mb0590c|M.bovis_AF2122/97 FIWFFRHPN-----------------------PIRPVVSQRCDAHDELRP
Mflv_2621|M.gilvum_PYR-GCK LGRIVNVRPAVLSG--------LAGRATALIPERMVTAHLAWIAAGSAFV
Mvan_3960|M.vanbaalenii_PYR-1 IGRIVNLRPAFLSG--------VASRASALIPEWAVASHLASIAAGSAFI
MUL_0294|M.ulcerans_Agy99 FKEYAPPRPG
MMAR_4675|M.marinum_M FKEYAPPRPG
MAV_0984|M.avium_104 VPDYAGSDV-
MSMEG_5719|M.smegmatis_MC2_155 LPQWPARLNG
MAB_2678|M.abscessus_ATCC_1997 LRDYQGLISR
Rv1260|M.tuberculosis_H37Rv IKDY------
Mb0590c|M.bovis_AF2122/97 AGDAVRRQRA
Mflv_2621|M.gilvum_PYR-GCK LPTAADLAR-
Mvan_3960|M.vanbaalenii_PYR-1 LPTAGDVGG-