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PSLRALECLVAVADSGSITQAARRLHSSQPAVSHQLAVLEREAQTVLLRREPRGVTLTPAGRAAVADARR AIDAAASAVRSARAVGEAAGGALRLACAQSLTVPLLAPVIRRWHRRHPDVAISLREAATIETFLDLVDAG EVDVALVPLPVPDRFATTFVADEEIVLAAASGHPLTRGSTVRMPDLQGAQIVHFAPENGLGGWLDRSLTA AGVHTETVMRTAASAAAPQLAAAGLGVAICPVSAVGAGFPGAVRSFSPRWVRKLVAVTPAKPDPLTARFI GDLQTRGVYVPSDVRSQLTNPSRTKAARTDATSRSSKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6882 | - | - | 100% (319) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6677 | - | 3e-27 | 32.40% (287) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 3e-27 | 32.39% (247) | LysR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 9e-13 | 27.67% (253) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 1e-28 | 34.15% (287) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 9e-13 | 27.67% (253) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-17 | 30.52% (249) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 8e-21 | 30.08% (246) | LysR family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 2e-18 | 29.96% (247) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_4979 | - | 4e-25 | 30.88% (285) | transcriptional regulator, LysR family protein, putative |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-14 | 27.97% (261) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 7e-18 | 29.55% (247) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 2e-24 | 34.68% (248) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3565|M.gilvum_PYR-GCK -----------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVS
Mvan_3362|M.vanbaalenii_PYR-1 -----------------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVS
MAB_2238|M.abscessus_ATCC_1997 -----------------MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVS
MMAR_2756|M.marinum_M --MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLS
MUL_2998|M.ulcerans_Agy99 -------MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLS
MLBr_02041|M.leprae_Br4923 ----------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLS
Mb2303c|M.bovis_AF2122/97 ----------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVS
Rv2282c|M.tuberculosis_H37Rv ----------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVS
MSMEG_6882|M.smegmatis_MC2_155 ----------------MPSLRALECLVAVADSGSITQAARRLHSSQPAVS
MAV_4979|M.avium_104 MLLAVSAVGGPESRCVMATLLQLKAFLAVVDQGGFTAASRSLGMSQPAVS
TH_3504|M.thermoresistible__bu ------------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALS
: : ::*:.: : *: * :*
Mflv_3565|M.gilvum_PYR-GCK AQIRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVD
Mvan_3362|M.vanbaalenii_PYR-1 AQIRRLERQVGQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVD
MAB_2238|M.abscessus_ATCC_1997 AQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAAVDGVREAAD
MMAR_2756|M.marinum_M QALAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAA
MUL_2998|M.ulcerans_Agy99 QALAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAA
MLBr_02041|M.leprae_Br4923 QALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAA
Mb2303c|M.bovis_AF2122/97 RRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLG
Rv2282c|M.tuberculosis_H37Rv RRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLG
MSMEG_6882|M.smegmatis_MC2_155 HQLAVLEREAQTVLLRREPRGVTLTPAGRAAVADARRAIDAAASAVRSAR
MAV_4979|M.avium_104 RAVAGLERELGSPLLIRHRDRILLNAPGKRALAHARSAVRHLDQMRAEVS
TH_3504|M.thermoresistible__bu SAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVR
: :* * * :. * . :
Mflv_3565|M.gilvum_PYR-GCK DVAGLLRGSVAIGTV-TLHPMNVAHLIAEFHADHP-----DVEITLGTAT
Mvan_3362|M.vanbaalenii_PYR-1 DVANLVRGAVAIGTV-TLHPVDVARLMADFHAEHP-----GVEITLGTDT
MAB_2238|M.abscessus_ATCC_1997 EIGGLIRGHIAFGTV-TSHGADLSSLLSAFHRDHP-----AISITLTEAG
MMAR_2756|M.marinum_M GEADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLP-----TLTVRVIEDQ
MUL_2998|M.ulcerans_Agy99 GEADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLP-----TLTVRVIEDQ
MLBr_02041|M.leprae_Br4923 GESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLP-----TLTLRVVEDQ
Mb2303c|M.bovis_AF2122/97 SLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATN
Rv2282c|M.tuberculosis_H37Rv SLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATN
MSMEG_6882|M.smegmatis_MC2_155 AVGEAAGGALRLACAQSLTVPLLAPVIRRWHRRHP-----DVAISLREAA
MAV_4979|M.avium_104 -AAAKLRGTLRIASLPYTTELLIAPQLQKFSERHP-----SVEIRVLEGG
TH_3504|M.thermoresistible__bu QTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYP-----STSFTLRQLY
. : . :
Mflv_3565|M.gilvum_PYR-GCK -SDVLIAELGDGRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPL
Mvan_3362|M.vanbaalenii_PYR-1 -SDVLLAKLEDGRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRL
MAB_2238|M.abscessus_ATCC_1997 -CEELVAGLREGRLDGAIVALGAQR-LAGLGLQVIDDQPLVAAVAADDLL
MMAR_2756|M.marinum_M -TERLLTALREGSLDTALIALPADY--GGLTEIPIYEEDFVLALPPGHPM
MUL_2998|M.ulcerans_Agy99 -TERLLTALREGSLDTALIALPADY--GGLTEIPIYEEDFVLALPPGHPM
MLBr_02041|M.leprae_Br4923 -TEHLLTALREGALDAAMIALPVET--AGIAEIPIYDEDFVLALPPGHPL
Mb2303c|M.bovis_AF2122/97 -SEHAIAAVRDGIADLGFIENPCPP--TGLGSVVVARDELVVVVPPGHKW
Rv2282c|M.tuberculosis_H37Rv -SEHAIAAVRDGIADLGFIENPCPP--TGLGSVVVARDELVVVVPPGHKW
MSMEG_6882|M.smegmatis_MC2_155 TIETFLDLVDAGEVDVALVPLPVPD---RFATTFVADEEIVLAAASGHPL
MAV_4979|M.avium_104 -EPEIRDWLDLGAADAGVISLPATG----LSAAFLAAQDMVAVLPSEHRL
TH_3504|M.thermoresistible__bu -PDALTDAVFDGTVQLGLRRGVVPT--PELATAVIGYHRVRVAFVDSHPL
: * : .. : : . . . .
Mflv_3565|M.gilvum_PYR-GCK AHR-RSLSLEQLS--RHPLISLPAGTGLRTRLDTACAA---AGLRPRIA-
Mvan_3362|M.vanbaalenii_PYR-1 ARR-KSLSLKQLC--EYPVISLPAGTGLRSRLDDACAA---AGLRPRIA-
MAB_2238|M.abscessus_ATCC_1997 ATR-RTITLQRLC--EHTLICLPTGSGVRSILESECRS---LGLSPNVA-
MMAR_2756|M.marinum_M ADR-HGVPVAALS--ELPLLLLDEGHCLRDQALDVCQN---AGVRAELAD
MUL_2998|M.ulcerans_Agy99 ADR-HGVPVAALS--ELPLLLLDEGHCLRDQALDVCQN---AGVRAEHAD
MLBr_02041|M.leprae_Br4923 SGK-RRVPTTALA--QLPLLLLDEGHCLRDQTLDICRK---SGVQAELAN
Mb2303c|M.bovis_AF2122/97 ARRSRVVSARELA--QTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPV
Rv2282c|M.tuberculosis_H37Rv ARRSRVVSARELA--QTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPV
MSMEG_6882|M.smegmatis_MC2_155 TRG-STVRMPDLQ--GAQIVHFAPENGLGGWLDRSLTA---AGVHTETVM
MAV_4979|M.avium_104 AAF-SEVHYADLA--KEPFIR--STGGCAHVFMAVADQ---VGVEFDVA-
TH_3504|M.thermoresistible__bu AAR-ESVDITELAREQVALWAPPGTSYYSDFLMGACRR---AGFEPDYVV
: : * . ..
Mflv_3565|M.gilvum_PYR-GCK FEATSPAELAELARHGLGVAILPQSMARGGS-----GLHALRLA----PE
Mvan_3362|M.vanbaalenii_PYR-1 FEATSPLELADLARHGLGVAILPRSMARGSA-----GLHPLRLS----PE
MAB_2238|M.abscessus_ATCC_1997 FEASSPRALVSLVEQGLGIAVVPAPYVRNRA-----GVLALDIR----PA
MMAR_2756|M.marinum_M TRAASLATAVQCVNGGLGVTLIPQSAVSVEA-----ARSRVGLAHFAAPT
MUL_2998|M.ulcerans_Agy99 TRADSLATAVQCVNGGLGVTLIPQSAVSVEA-----ARSRVGLTHFAAPT
MLBr_02041|M.leprae_Br4923 TRAASLATAVQCVTGGLGVTLLPQSAAPVES-----VRSKLGLAQFAAPC
Mb2303c|M.bovis_AF2122/97 LELSSAAAVRAAVLAGAGPAAMSRLAIADDL-----AFGRLLAVDIPALN
Rv2282c|M.tuberculosis_H37Rv LELSSAAAVRAAVLAGAGPAAMSRLAIADDL-----AFGRLLAVDIPALN
MSMEG_6882|M.smegmatis_MC2_155 RTAAS-AAAPQLAAAGLGVAICPVSAVGAGFPGAVRSFSPRWVRKLVAVT
MAV_4979|M.avium_104 FEAHGLMAVLEIVTAGLGVSIVPVAAVARPR-------AGIAVKR---LV
TH_3504|M.thermoresistible__bu SRVQGAATVAAPLTTG-GIAFVTAAAGPTMN-------GRVQVVDLT-PP
. * * : .
Mflv_3565|M.gilvum_PYR-GCK LRGRLVWAWRADG-ANPAARVLGERARAMAVSPGSGAPAVVPGA------
Mvan_3362|M.vanbaalenii_PYR-1 LRGRLVWAWRTDI-SGPAARLLNARARAMIAATG--TPAVIPGA------
MAB_2238|M.abscessus_ATCC_1997 LRGRLALAWRLDGPVGPAARAFLERARAVL--------------------
MMAR_2756|M.marinum_M PGRRIGLVYRASSGRDEAYRQLAAIMGESISNEQQVRLVN----------
MUL_2998|M.ulcerans_Agy99 PGRRIGLVYRASSGRDEAYRQLAAIMGESISNEQQVRLVN----------
MLBr_02041|M.leprae_Br4923 PGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA----------
Mb2303c|M.bovis_AF2122/97 LRRQLRAIWVGGR--TPPAGAIRDLLSHITSRST----------------
Rv2282c|M.tuberculosis_H37Rv LRRQLRAIWVGGR--TPPAGAIRDLLSHITSRST----------------
MSMEG_6882|M.smegmatis_MC2_155 PAKPDPLTARFIGDLQTRGVYVPSDVRSQLTNPSRTKAARTDATSRSSKK
MAV_4979|M.avium_104 PKTTRNLAVAVSASAGSAARAFLEQIAALDGSERAGA-------------
TH_3504|M.thermoresistible__bu LLVPVQALWQRHTLSAIRDRILEGLG------------------------
.