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MAASARRVGAETSKTRDTLLDHVEQMMLGEGYASVSYRALASAAGVTPSLVQYYFPTLDDIFLAAIRRYS ERNLAQLQKALAARIDDPLRALWEYSRSEATGALMTEFMALGNHRKSIRAEIAEVTERGRKIQLDALVAK FGKDARPGGHFSLPALLLLISGLPKFLSLEEGIGVKTAHKEVTAAFEKYLDEIEPTPRRKRSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6628 | - | - | 100% (203) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4779 | - | 5e-31 | 37.95% (195) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6032 | - | 1e-28 | 36.41% (195) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 8e-06 | 40.00% (65) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_1270 | - | 6e-83 | 77.00% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 8e-06 | 40.00% (65) | hypothetical protein Rv1685c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1578c | - | 6e-07 | 35.56% (90) | putative transcriptional regulator TetR |
| M. marinum M | MMAR_4693 | - | 2e-33 | 40.20% (199) | transcriptional regulator |
| M. avium 104 | MAV_1394 | - | 2e-49 | 62.99% (154) | hypothetical protein MAV_1394 |
| M. thermoresistible (build 8) | TH_1623 | - | 3e-83 | 78.28% (198) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 6e-08 | 28.57% (154) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4140 | - | 3e-31 | 38.69% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6628|M.smegmatis_MC2_155 ---------MAASARRVG--AETSKTRDTLLDHVEQMMLGEGYASVSYRA
Mflv_1270|M.gilvum_PYR-GCK ---------MATSSRRVG--AETSKTRDTLLDCVETMMLEEGYASVTYRA
TH_1623|M.thermoresistible__bu VRSRSNEETMASSTRRVG--AETSKTRDTLLNCVEQMMLAEGYASVTYRA
MAV_1394|M.avium_104 --------------------------------------------------
MMAR_4693|M.marinum_M ----------MTSARRIG--APDAKNRGVLLDTAEELMIEEGYAAVTSRR
Mvan_4140|M.vanbaalenii_PYR-1 ----------MTSPRRIG--APDAKNRVVLLDAAEQLLIEEGYAAVTSRR
Mb1711c|M.bovis_AF2122/97 ------MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRA
Rv1685c|M.tuberculosis_H37Rv ------MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRA
MAB_1578c|M.abscessus_ATCC_199 ---------------------MTRDTRTLLLDAAEQVLLDDGLAGASLRR
MUL_4876|M.ulcerans_Agy99 -MTVPTFSTRSQLGRPVG--ARGEQTRQRIITAAMRCVAEAGPAQASIRE
MSMEG_6628|M.smegmatis_MC2_155 LASAAGVTPSLVQYYFPTLDDIFLAAIRRYSERNLAQLQKALAARIDDPL
Mflv_1270|M.gilvum_PYR-GCK LAAKAGVTPSLVQYYFPTLDDVFIAAIRRYSERNLAHLNKVMEKRAEDPL
TH_1623|M.thermoresistible__bu LAAKAGVTPSLVQYYFPTLDDIFIAAIRRYSERNIAQLNKVLAERADDPL
MAV_1394|M.avium_104 -----------MQYYFPSLDDIFVAAIRRYSERNMEWLTEELQRRADDPL
MMAR_4693|M.marinum_M VASEAGLKPQLVHYYFRTMEELFLELFRRRAEEGLRAQAQALQS--PKPL
Mvan_4140|M.vanbaalenii_PYR-1 VADRAGLKPQLVHYYFRTMEDLFLAVFHRRAEEGLAVLSTALAS--PQPL
Mb1711c|M.bovis_AF2122/97 VAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDP-MVIIGPIREAPVEELG
Rv1685c|M.tuberculosis_H37Rv VAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDP-MVIIGPIREAPVEELG
MAB_1578c|M.abscessus_ATCC_199 ITAVAGVNVAAVNYTFGSKEALLDALLTRVMEPVLAERAKRLDEVAGTPG
MUL_4876|M.ulcerans_Agy99 IAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAAS-SDDIV
: : * . . :: : :
MSMEG_6628|M.smegmatis_MC2_155 RALWEYSRSEATGALMTEFMALGNHRKSIRAEIAEVT----------ERG
Mflv_1270|M.gilvum_PYR-GCK RALWEYSWDEATGTLMTEFMALGNHRKSIRTEIAAVT----------ESV
TH_1623|M.thermoresistible__bu RALWEYSWDEATGALMTEFMALGNHRKNIRSEIASAT----------RKV
MAV_1394|M.avium_104 HALWESSWHESTSALMTEFMALGNHRKSIRSEIAAVT----------DSM
MMAR_4693|M.marinum_M WALWRLGSDPAFARISMEFMALANHRKALRAEIAHYA----------ERF
Mvan_4140|M.vanbaalenii_PYR-1 WALWRFSTAPEATRLTMEFMGLANHRKALRAEIVYYA----------ERF
Mb1711c|M.bovis_AF2122/97 YKLPSLLLPIWDSELGAGLIAT--LRSLISGSDVGLA----------RSF
Rv1685c|M.tuberculosis_H37Rv YKLPSLLLPIWDSELGAGLIAT--LRSLISGSDVGLA----------RSF
MAB_1578c|M.abscessus_ATCC_199 HTVDDLVRALLESMLRVDQRHVALYAEVSVKPRLGGD----------QRF
MUL_4876|M.ulcerans_Agy99 DRLDAVLDE--SKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPGSKAL
: :
MSMEG_6628|M.smegmatis_MC2_155 RKIQLDALVAKFGKDARPGG--HFSLPALLLLISGLPKFLSLEEGIGVKT
Mflv_1270|M.gilvum_PYR-GCK RTLQLDALTAKFGADARPWG--DLSLPALQLLISSLPKFLNLEKGVGVET
TH_1623|M.thermoresistible__bu RKIQLDALSAKFGKDARLGAEFDLSLPALQLLLSGLPKLLNLEAGVGVKT
MAV_1394|M.avium_104 RRVQVEALVAKFGNDARLLA--DLSFDAVVLLINGVPKLLGLEESVGVDT
MMAR_4693|M.marinum_M RDEQRRVITAALQRYGVDSQ--DVPPVVWTVLMASLSRFLVLEKALGMSG
Mvan_4140|M.vanbaalenii_PYR-1 RQEQNRAIADALQRYGTDFT--DVPPVVWTVFATSVSQALVMERALGMDT
Mb1711c|M.bovis_AF2122/97 LEEVVTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLP
Rv1685c|M.tuberculosis_H37Rv LEEVVTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLP
MAB_1578c|M.abscessus_ATCC_199 DETRRSSVQTGIDRVTAALAP-LLPGQPPEVLGYRVERLLKMATIHVLDG
MUL_4876|M.ulcerans_Agy99 RDVITEIVDDARGRGVLSAG--IAPGAAVDAICALTRGLTEQAANLGPQS
:
MSMEG_6628|M.smegmatis_MC2_155 AHKEVTAAFEKYLDEIEP-------------TPRRK-----RSR----
Mflv_1270|M.gilvum_PYR-GCK AHAELIEAFEGYLNSIEP-------------TPKRKPVPRKRSR----
TH_1623|M.thermoresistible__bu AHHEMAAAFERYMDALQPTAGTAETKTGAKSTPQRKS-AAHRPKSPGH
MAV_1394|M.avium_104 AHAELIAACERFLDAVEP-----------RAKPRRRSKKAPTRRR---
MMAR_4693|M.marinum_M GHAETIELVESYLRRLEG-------------EP---------------
Mvan_4140|M.vanbaalenii_PYR-1 GHAETFAFCEEWIRRLEG-------------DPLPPLDQRA-------
Mb1711c|M.bovis_AF2122/97 AEQIVQTIAPNLQRYLTG------------ELPDDLAP----------
Rv1685c|M.tuberculosis_H37Rv AEQIVQTIAPNLQRYLTG------------ELPDDLAP----------
MAB_1578c|M.abscessus_ATCC_199 MQLAQKYGLDPGADGQDLIDDLVAFFSAGLAAPTPLTLRPASVP----
MUL_4876|M.ulcerans_Agy99 YDVTLDSAKQLLRGSLFAG-----------AKPTATRRT---------
. *