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TRDTRTLLLDAAEQVLLDDGLAGASLRRITAVAGVNVAAVNYTFGSKEALLDALLTRVMEPVLAERAKRL DEVAGTPGHTVDDLVRALLESMLRVDQRHVALYAEVSVKPRLGGDQRFDETRRSSVQTGIDRVTAALAPL LPGQPPEVLGYRVERLLKMATIHVLDGMQLAQKYGLDPGADGQDLIDDLVAFFSAGLAAPTPLTLRPASV P*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1578c | - | - | 100% (212) | putative transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_0835c | - | 1e-10 | 43.53% (85) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0145c | - | 2e-09 | 33.09% (139) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 3e-09 | 33.33% (186) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 1e-07 | 37.21% (86) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 4e-09 | 33.33% (186) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0204 | - | 1e-07 | 28.00% (175) | hypothetical protein MMAR_0204 |
| M. avium 104 | MAV_1611 | - | 1e-08 | 28.27% (191) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6537 | - | 4e-07 | 28.65% (178) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2855 | - | 2e-07 | 34.29% (105) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4899 | - | 9e-08 | 28.00% (175) | hypothetical protein MUL_4899 |
| M. vanbaalenii PYR-1 | Mvan_2880 | - | 2e-11 | 39.58% (96) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0335|M.bovis_AF2122/97 ----------------------------------MQQQRTNRDKLLDGAL
Rv0328|M.tuberculosis_H37Rv ----------------------------------MQQQRTNRDKLLDGAL
MMAR_0204|M.marinum_M --------------------------------MKTRDATATRSAILDAAQ
MUL_4899|M.ulcerans_Agy99 ------------------------------MPVKTRDATATRSAILDAAQ
MAB_1578c|M.abscessus_ATCC_199 ------------------------------------MTRDTRTLLLDAAE
Mvan_2880|M.vanbaalenii_PYR-1 ---------------------------------MSRIEADTREHLLTVAE
MSMEG_6537|M.smegmatis_MC2_155 ------------------------------MDTSTANAAATRVRLVDAAV
MAV_1611|M.avium_104 ---------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAA
Mflv_2327|M.gilvum_PYR-GCK ---------------------------MAERWTKERRTEHTRQILLDAAE
TH_2855|M.thermoresistible__bu LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPEEIVSAAA
:: *
Mb0335|M.bovis_AF2122/97 ACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDA--LGRCFST
Rv0328|M.tuberculosis_H37Rv ACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDA--LGRCFST
MMAR_0204|M.marinum_M SQFGENGFERTTIRSVAKAAGVDPALVMHYFGSKAGLFTAATRFDIKFPD
MUL_4899|M.ulcerans_Agy99 SQFGENGFERTTIRSVAKAAGVDPALVMHYFGSKAGLFTAATRFDIKFPD
MAB_1578c|M.abscessus_ATCC_199 QVLLDDGLAGASLRRITAVAGVNVAAVNYTFGSKEALLDAL--LTRVMEP
Mvan_2880|M.vanbaalenii_PYR-1 RLFLDAGYENVSVRAVCATAGVNPAAVHYHFGSKVGLVSAL--LEARLGP
MSMEG_6537|M.smegmatis_MC2_155 RLITRHGFAGTSLQMIADELGFTKAAIYYHFRTREQLLGAVVEPFLSELQ
MAV_1611|M.avium_104 KVFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLAL--LDREFEL
Mflv_2327|M.gilvum_PYR-GCK EVFARKGLTGAALEEIADAAGFTRGAIYSQFGAKEKLFLAV--VDRQRER
TH_2855|M.thermoresistible__bu EFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICLTVTKEPN
: * . : *. . : * :: :.
Mb0335|M.bovis_AF2122/97 WN----QRVQEAFD--HSRAAGPAGQILA--VLEATVDSFE-QIRPAVYA
Rv0328|M.tuberculosis_H37Rv WN----QRVQEAFD--HSRAAGPAGQILA--VLEATVDSFE-QIRPAVYA
MMAR_0204|M.marinum_M LSGIPMDRIADALLPNFLRVWGPRGAFLP--LLRAAASNRD-AADALVEV
MUL_4899|M.ulcerans_Agy99 LSGIPMDRIADALLPNFLRVWGPRGAFLP--LLRAAATNRD-AADALVEV
MAB_1578c|M.abscessus_ATCC_199 VLAERAKRLDEVAGTPGHTVDDLVRALLE--SMLRVDQRHV-ALYAEVSV
Mvan_2880|M.vanbaalenii_PYR-1 LW---EDALTEAAGEGPAGISDAVRIVVE--PLVELAGDPAGRLYLHLLS
MSMEG_6537|M.smegmatis_MC2_155 TVIDDAERLRGVHARADHMVRGYAGLAVRNRALVSVLAGDP-SVNEALKT
MAV_1611|M.avium_104 RGQQIAIALDRSAGDTTAAAREVSRSVLD-------------SVRDHSDY
Mflv_2327|M.gilvum_PYR-GCK FLDGFADVMDSFHRLSDVDIDELAQRWRQ-----------LSSGADRAAL
TH_2855|M.thermoresistible__bu ELN---LPLLDAAGTPAERLSALIRAHLEH------------LIRRRVEH
:
Mb0335|M.bovis_AF2122/97 CVESYAPALRSEALRERLAAGYADVRQHSVDLAGAALAGTDIAPPENLST
Rv0328|M.tuberculosis_H37Rv CVESYAPALRSEALRERLAAGYADVRQHSVDLAGAALAGTDIAPPENLST
MMAR_0204|M.marinum_M FVDRVGPALSAIVPDR----GPERAALVAAQMVGVATARYVIGLPPLLHM
MUL_4899|M.ulcerans_Agy99 FVDRVGPALSAIVPDR----GPERAALVAAQMVGVATARYVIGLPPLLHM
MAB_1578c|M.abscessus_ATCC_199 KPRLGGDQRFDETRRSSVQTGIDRVTAALAPLLPGQPPEVLGYRVERLLK
Mvan_2880|M.vanbaalenii_PYR-1 RLLLARVELSWTRRWFAVAPWVALLRRHLPELSERDAEARWMLAFELIFT
MSMEG_6537|M.smegmatis_MC2_155 RPEWAALIDRQMRLLTDVAPGPAGRVKAMMVFSGMSAAAGPASDDIPVEE
MAV_1611|M.avium_104 YVLLVEYWLRAQRDPQLRERLIERRRAAADQALHIVESTDTVPGDRRLTD
Mflv_2327|M.gilvum_PYR-GCK GYELTLYLLRNPDARASVAAQRRETIRALGEFISKNVARIGGTLTIEAET
TH_2855|M.thermoresistible__bu LVALHDINSLTPEHRAIIDDLRRYYQRRVRDVIVAGVRSGEFDVPD-PKL
Mb0335|M.bovis_AF2122/97 IVSVLMAVIDGLMIQWIADPSATPR-STEVIRALASIGAVVTSQLR----
Rv0328|M.tuberculosis_H37Rv IVSVLMAVIDGLMIQWIADPSATPR-STEVIRALASIGAVVTSQLR----
MMAR_0204|M.marinum_M DDEELIRWLRPVIVHYLTDPAP----------------------------
MUL_4899|M.ulcerans_Agy99 DDEELIRWLRPVIVHYLTDPAP----------------------------
MAB_1578c|M.abscessus_ATCC_199 MATIHVLDGMQLAQKYGLDPGADGQDLIDDLVAFFSAGLAAPTPLTLRPA
Mvan_2880|M.vanbaalenii_PYR-1 QFGDPLAGDRRLSARRVQT-----------LQAFVAAGLSAPVESR----
MSMEG_6537|M.smegmatis_MC2_155 LYAHLVDTSRRALGLRAPREKA----------------------------
MAV_1611|M.avium_104 IAQLVVTLNLGVAMEEVLRPGTINPDLLAQLITALLESIPV---------
Mflv_2327|M.gilvum_PYR-GCK LARIVLAANDGVTLDSHIDGEDLYRPYLQLVMSSVQTPH-----------
TH_2855|M.thermoresistible__bu AALLILDALNGVSGWFHPDRGHSLPDVIAAYTEMIVERVLRARIS-----
:
Mb0335|M.bovis_AF2122/97 ---
Rv0328|M.tuberculosis_H37Rv ---
MMAR_0204|M.marinum_M ---
MUL_4899|M.ulcerans_Agy99 ---
MAB_1578c|M.abscessus_ATCC_199 SVP
Mvan_2880|M.vanbaalenii_PYR-1 ---
MSMEG_6537|M.smegmatis_MC2_155 ---
MAV_1611|M.avium_104 ---
Mflv_2327|M.gilvum_PYR-GCK ---
TH_2855|M.thermoresistible__bu ---