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VFKSTLSRFIPAVSAALLTAGLVPGTAGTANAEPPIEGAAPPCPDVEVVFARGTFEPPGVGFVGQAFVDA LRGRLGDKSVDVYAVNYPASLDFQRAADGIVDASRKVEQTAATCPSTKTVIGGFSQGAAVAAYLTADSVP ANFVLPDGITGPMPDDVAKHVTAVTLFGKPSNGFINTVQSTAPPINIGHLYTDKTVDLCIETDPVCSPTG SDGASHNLYATNGMVQQAADYVAARVLPQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6354 | - | - | 100% (239) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_4465 | - | 7e-67 | 54.24% (236) | cutinase |
| M. smegmatis MC2 155 | MSMEG_2474 | - | 4e-64 | 55.45% (220) | cutinase Cut3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 3e-57 | 54.81% (208) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 1e-54 | 50.46% (216) | cutinase |
| M. tuberculosis H37Rv | Rv1758 | cut1 | 1e-44 | 53.53% (170) | cutinase Cut1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3272c | - | 1e-70 | 64.36% (188) | cutinase Cut1 |
| M. marinum M | MMAR_5251 | cut5 | 1e-53 | 55.22% (201) | cutinase, Cut5 |
| M. avium 104 | MAV_2961 | - | 8e-57 | 53.39% (221) | cutinase Cut3 |
| M. thermoresistible (build 8) | TH_0238 | - | 2e-56 | 52.77% (235) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 5e-53 | 54.23% (201) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | 2e-72 | 59.01% (222) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4439|M.gilvum_PYR-GCK MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAPGPAPPPIAAPAPE
MAV_2961|M.avium_104 -------------MLSPFWALLLG------PALV---GTAAP--------
Mb1788|M.bovis_AF2122/97 --------------MVTTWALLFA------PVPAASADPPDPT-------
Rv1758|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5251|M.marinum_M -------------MRNATWTRRLAVG--AATAVTALVGWGIRVP------
MUL_4327|M.ulcerans_Agy99 -------------MRNATWTRRLAVG--AATAVTALVGGGIRVP------
TH_0238|M.thermoresistible__bu ----------LSRIGSAVGAALTTASLITGTVITSTVVAGTAVP------
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5804|M.vanbaalenii_PYR-1 -------MNIFSRWLAVAASVVAVTG---GLPLAAAPAYAAP--------
MSMEG_6354|M.smegmatis_MC2_155 -----MFKSTLSRFIPAVSAALLTAG---LVPGTAGTANAEPPI------
Mflv_4439|M.gilvum_PYR-GCK PLAAPVAGCPDVEIVFARGTTEAPGLGAMGQAFVEDLRSRLGGKTVGVYA
MAV_2961|M.avium_104 ---AAADSCPDVEVVFARGTSEPPGVGRIGQSFVDTLRSRLGTKSVGVYP
Mb1788|M.bovis_AF2122/97 ---VSDGACPDVEVVFARGTGEPPGVGGIGEDFIDALRSKIGEKSMGVYG
Rv1758|M.tuberculosis_H37Rv ---------------------MP---GRFREDFIDALRSKIGEKSMGVYG
MMAR_5251|M.marinum_M --FAAAEPCPDVEVLFARGTGEPPGIGGIGGSFVAALRSDIGAKSLAVYA
MUL_4327|M.ulcerans_Agy99 --FVAAEPCPDVEVLFARGTGEPPGIGGIGGSFVAALRSDIGAKSSAVYA
TH_0238|M.thermoresistible__bu --AAAAQPCPDVQVVFARGTGEPPGVGPTGQAFIDALRPRVGDRSLDVYA
MAB_3272c|M.abscessus_ATCC_199 --------------MFARGTFEPPGVGGTGESFVNALRARTKGKSVEVYP
Mvan_5804|M.vanbaalenii_PYR-1 --------CPDVEVVFARGTFEPPGIGATGQAFVDSLRSRAGGRTVDVYA
MSMEG_6354|M.smegmatis_MC2_155 --EGAAPPCPDVEVVFARGTFEPPGVGFVGQAFVDALRGRLGDKSVDVYA
. * *: ** :: **
Mflv_4439|M.gilvum_PYR-GCK VDYPASPDFPTA------VEGIADASTHVQQIAMNCPDTKLVLGGYSQGA
MAV_2961|M.avium_104 VNYPATTDFPTA------ADGISDAGAHVQQMAANCPRTKMVLGGYSQGA
Mb1788|M.bovis_AF2122/97 VDYPATTDFPTA------MAGIYDAGTHVEQTAANCPQSKLVLGGFSQGA
Rv1758|M.tuberculosis_H37Rv VDYPATTDFPTA------MAGIYDAGTHVEQTAANCPQSKLVLGGFSQGA
MMAR_5251|M.marinum_M VDYPASSDFSSSDFPRTVIEGIRDASSHIESMAAKCPATREVLGGYSQGA
MUL_4327|M.ulcerans_Agy99 IDYPASSDFSSSDFPRTVIDGIRDASSHIESMAAKCPATREVLGGYSQGA
TH_0238|M.thermoresistible__bu VNYPAIDVWNTG------IDGIRDAGAHVVRMAEQCPDTRLVLGGFSQGA
MAB_3272c|M.abscessus_ATCC_199 VEYPASLAFATA------ADGVIDASNRVKDVAARCPNTKIVMGGFSQGA
Mvan_5804|M.vanbaalenii_PYR-1 VNYPASFDFATA------ADGVIDASNRVVTMAANCPDTQLVLGGFSQGA
MSMEG_6354|M.smegmatis_MC2_155 VNYPASLDFQRA------ADGIVDASRKVEQTAATCPSTKTVIGGFSQGA
::*** : . *: **. :: * ** :: *:**:****
Mflv_4439|M.gilvum_PYR-GCK AVMGFVTTELIPDGVSLS-EVPAPMPPDIADHVAAVALLGAPSDRFMDMI
MAV_2961|M.avium_104 AVMGFVTESAVPDGVQLV-QSLQPMPAAVANHVAAVALFGKPSAQFMSII
Mb1788|M.bovis_AF2122/97 AVMGFVTAAAIPDGAPL--DAPRPMPPEVADHVAAVTLFGMPSVAFMHSI
Rv1758|M.tuberculosis_H37Rv AVMGFVTAAAIPDGAPL--DAPRPMPPEVADHVAAVTLFGMPSVAFMHSI
MMAR_5251|M.marinum_M AVAGYVTSASVPPGVPAA-AVPKPMAPDIADHVAAVTLFGTPSEQFLQHY
MUL_4327|M.ulcerans_Agy99 AVAGYVTSASVPPGVPAA-AVPKPMAPDIADYVAAVTLFGTPSEQFLQHY
TH_0238|M.thermoresistible__bu AVMGFVTSAEVPAGVDPA-TVPKPLDPDIAEHVAAVVLFGMPNARAMNFL
MAB_3272c|M.abscessus_ATCC_199 AVVAYTTADAVPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQRI
Mvan_5804|M.vanbaalenii_PYR-1 AVAAYITEDTIPEGYTPPPGMTGPMPPSVADNVAAVALFGKPSSGFLQMI
MSMEG_6354|M.smegmatis_MC2_155 AVAAYLTADSVPANFVLPDGITGPMPDDVAKHVTAVTLFGKPSNGFINTV
** .: * :* . *: :*. *:**.*:* *. :
Mflv_4439|M.gilvum_PYR-GCK K--QPPVTIGALYQPKTLELCVPGDFVCSP-GNDLGAHARYISDG-LVVQ
MAV_2961|M.avium_104 N--EPPVTIGPLYAAKTIELCVPGDPICSG-AVNPAAHRQYVEAG-MVDQ
Mb1788|M.bovis_AF2122/97 G--APPIVIGPLYAEKTIQLCAPGDPVCSS-GGNWAAHNGYADDG-MVEQ
Rv1758|M.tuberculosis_H37Rv G--APPIVIGPLYAEKTIQLCAPGDPVCSS-GGNWAAHNGYADDG-MVEQ
MMAR_5251|M.marinum_M G--APPITIGPLYQPRTVELCASGDPVCSG-GNDAAAHALYAVNG-MTGQ
MUL_4327|M.ulcerans_Agy99 G--APPITIGPLYQPRTIELCASGDPVCSG-GNDAAAHALYAVNG-MTGQ
TH_0238|M.thermoresistible__bu G--TPPVVIGPLYEDKTVKLCAVDDPVCSN-GMNFAAHNTYATNAAMVDQ
MAB_3272c|M.abscessus_ATCC_199 DNTAPPINIGHLYVAKTMDMCVPEDPICSPDGSDNAAHGSYGDNG-MTSQ
Mvan_5804|M.vanbaalenii_PYR-1 YTGAPPINVGSRYAAKTLDLCIPEDPVCSPTGRDNAAHGGYALTG-MTDR
MSMEG_6354|M.smegmatis_MC2_155 QSTAPPINIGHLYTDKTVDLCIETDPVCSPTGSDGASHNLYATNG-MVQQ
**: :* * :*:.:* * :** . : .:* * . :. :
Mflv_4439|M.gilvum_PYR-GCK AADFAVGKLAETPAESGGAPA-------
MAV_2961|M.avium_104 AVDFTTDRV-------------------
Mb1788|M.bovis_AF2122/97 AAVFAAGRLG------------------
Rv1758|M.tuberculosis_H37Rv AAVFAAGRLG------------------
MMAR_5251|M.marinum_M GADFAAHHL-------------------
MUL_4327|M.ulcerans_Agy99 GADFAAHHL-------------------
TH_0238|M.thermoresistible__bu GAAFAADRLGVASDKPLPTPSSGQNFGN
MAB_3272c|M.abscessus_ATCC_199 AADFAARQIN-----SPTDTVSAAG---
Mvan_5804|M.vanbaalenii_PYR-1 AAEFAVRNMPRHGSEQPVDLAAGPR---
MSMEG_6354|M.smegmatis_MC2_155 AADYVAARVL------PQ----------
.. :.. .: