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FARGTFEPPGVGGTGESFVNALRARTKGKSVEVYPVEYPASLAFATAADGVIDASNRVKDVAARCPNTKI VMGGFSQGAAVVAYTTADAVPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQRIDNTAPPINIGH LYVAKTMDMCVPEDPICSPDGSDNAAHGSYGDNGMTSQAADFAARQINSPTDTVSAAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3272c | - | - | 100% (199) | cutinase Cut1 |
| M. abscessus ATCC 19977 | MAB_3809c | - | 1e-31 | 38.07% (197) | cutinase Cut4 |
| M. abscessus ATCC 19977 | MAB_3766 | - | 3e-26 | 37.31% (193) | cutinase cut3 precursor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 3e-52 | 55.32% (188) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 6e-51 | 51.60% (188) | cutinase |
| M. tuberculosis H37Rv | Rv1758 | cut1 | 9e-44 | 52.33% (172) | cutinase Cut1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5251 | cut5 | 5e-49 | 51.55% (194) | cutinase, Cut5 |
| M. avium 104 | MAV_2961 | - | 4e-54 | 57.14% (189) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_6354 | - | 1e-70 | 64.36% (188) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_1243 | - | 2e-45 | 49.25% (199) | PROBABLE CUTINASE |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 2e-48 | 51.03% (194) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | 2e-73 | 67.02% (188) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5804|M.vanbaalenii_PYR-1 ------------MN--IFSRWLAVAASVVAVTG-----------GLPLAA
MSMEG_6354|M.smegmatis_MC2_155 ----------MFKS--TLSRFIPAVSAALLTAG-----------LVPGTA
Mb1788|M.bovis_AF2122/97 ---------------------MVTTWALLFAP---------------VPA
Rv1758|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4439|M.gilvum_PYR-GCK -----MGLSECLSG--VTAPGLALAAGLLLAPHAFAQPALTPAPGPAPPP
MAV_2961|M.avium_104 --------------------MLSPFWALLLGP----------------AL
MMAR_5251|M.marinum_M -----MRNATWTRR----LAVGAATAVTALVG------------------
MUL_4327|M.ulcerans_Agy99 -----MRNATWTRR----LAVGAATAVTALVG------------------
TH_1243|M.thermoresistible__bu MGWVDMRVTELPNRSRSMFRLIGVISAFVLAGSM---------ACGIGFV
MAB_3272c|M.abscessus_ATCC_199 ---------------------MFARGTFEPPGVGGTGESFVNALRARTKG
Mvan_5804|M.vanbaalenii_PYR-1 APAYAAP--------CPDVEVVFARGTFEPPGIGATGQAFVDSLRSRAGG
MSMEG_6354|M.smegmatis_MC2_155 GTANAEPPIEGAAPPCPDVEVVFARGTFEPPGVGFVGQAFVDALRGRLGD
Mb1788|M.bovis_AF2122/97 ASADPPDPTVSDGA-CPDVEVVFARGTGEPPGVGGIGEDFIDALRSKIGE
Rv1758|M.tuberculosis_H37Rv ----------------------------MP---GRFREDFIDALRSKIGE
Mflv_4439|M.gilvum_PYR-GCK IAAPAPEPLAAPVAGCPDVEIVFARGTTEAPGLGAMGQAFVEDLRSRLGG
MAV_2961|M.avium_104 VGTAAP----AAADSCPDVEVVFARGTSEPPGVGRIGQSFVDTLRSRLGT
MMAR_5251|M.marinum_M ---WGIRVPFAAAEPCPDVEVLFARGTGEPPGIGGIGGSFVAALRSDIGA
MUL_4327|M.ulcerans_Agy99 ---GGIRVPFVAAEPCPDVEVLFARGTGEPPGIGGIGGSFVAALRSDIGA
TH_1243|M.thermoresistible__bu SAVMGVGSPTAAAQPCPDVEVIFARGTDEPPGVGGVGQAFIDELRPRIGD
. * *: **
MAB_3272c|M.abscessus_ATCC_199 KSVEVYPVEYPASLAFAT-------AADGVIDASNRVKDVAARCPNTKIV
Mvan_5804|M.vanbaalenii_PYR-1 RTVDVYAVNYPASFDFAT-------AADGVIDASNRVVTMAANCPDTQLV
MSMEG_6354|M.smegmatis_MC2_155 KSVDVYAVNYPASLDFQR-------AADGIVDASRKVEQTAATCPSTKTV
Mb1788|M.bovis_AF2122/97 KSMGVYGVDYPATTDFPT-------AMAGIYDAGTHVEQTAANCPQSKLV
Rv1758|M.tuberculosis_H37Rv KSMGVYGVDYPATTDFPT-------AMAGIYDAGTHVEQTAANCPQSKLV
Mflv_4439|M.gilvum_PYR-GCK KTVGVYAVDYPASPDFPT-------AVEGIADASTHVQQIAMNCPDTKLV
MAV_2961|M.avium_104 KSVGVYPVNYPATTDFPT-------AADGISDAGAHVQQMAANCPRTKMV
MMAR_5251|M.marinum_M KSLAVYAVDYPASSDFSS-SDFPRTVIEGIRDASSHIESMAAKCPATREV
MUL_4327|M.ulcerans_Agy99 KSSAVYAIDYPASSDFSS-SDFPRTVIDGIRDASSHIESMAAKCPATREV
TH_1243|M.thermoresistible__bu RSLSVYAVNYPASSNFGAGIEFARTVVDGIRDAADRVQTTAANCPDTRIV
:: ** ::***: * . *: **. :: * ** :: *
MAB_3272c|M.abscessus_ATCC_199 MGGFSQGAAVVAYTTADAVPPGFELPE--GITGPMPAEVADHVAAVALFG
Mvan_5804|M.vanbaalenii_PYR-1 LGGFSQGAAVAAYITEDTIPEGYTPPP--GMTGPMPPSVADNVAAVALFG
MSMEG_6354|M.smegmatis_MC2_155 IGGFSQGAAVAAYLTADSVPANFVLPD--GITGPMPDDVAKHVTAVTLFG
Mb1788|M.bovis_AF2122/97 LGGFSQGAAVMGFVTAAAIPDGAPL----DAPRPMPPEVADHVAAVTLFG
Rv1758|M.tuberculosis_H37Rv LGGFSQGAAVMGFVTAAAIPDGAPL----DAPRPMPPEVADHVAAVTLFG
Mflv_4439|M.gilvum_PYR-GCK LGGYSQGAAVMGFVTTELIPDGVSLS---EVPAPMPPDIADHVAAVALLG
MAV_2961|M.avium_104 LGGYSQGAAVMGFVTESAVPDGVQLV---QSLQPMPAAVANHVAAVALFG
MMAR_5251|M.marinum_M LGGYSQGAAVAGYVTSASVPPGVPAAA---VPKPMAPDIADHVAAVTLFG
MUL_4327|M.ulcerans_Agy99 LGGYSQGAAVAGYVTSASVPPGVPAAA---VPKPMAPDIADYVAAVTLFG
TH_1243|M.thermoresistible__bu LGGYSQGAALAGYVTAAAVPEEVPVEFRSYVPEPMPREVADHVAAVVLFA
:**:*****: .: * :* **. :*. *:**.*:.
MAB_3272c|M.abscessus_ATCC_199 KPSSGFLQRIDNTAPPINIGHLYVAKTMDMCVPEDPICSPDGSDNA---A
Mvan_5804|M.vanbaalenii_PYR-1 KPSSGFLQMIYTGAPPINVGSRYAAKTLDLCIPEDPVCSPTGRDNA---A
MSMEG_6354|M.smegmatis_MC2_155 KPSNGFINTVQSTAPPINIGHLYTDKTVDLCIETDPVCSPTGSDGA---S
Mb1788|M.bovis_AF2122/97 MPSVAFMHSIG--APPIVIGPLYAEKTIQLCAPGDPVCSS-GGNWA---A
Rv1758|M.tuberculosis_H37Rv MPSVAFMHSIG--APPIVIGPLYAEKTIQLCAPGDPVCSS-GGNWA---A
Mflv_4439|M.gilvum_PYR-GCK APSDRFMDMIK--QPPVTIGALYQPKTLELCVPGDFVCSP-GNDLG---A
MAV_2961|M.avium_104 KPSAQFMSIIN--EPPVTIGPLYAAKTIELCVPGDPICSG-AVNPA---A
MMAR_5251|M.marinum_M TPSEQFLQHYG--APPITIGPLYQPRTVELCASGDPVCSG-GNDAA---A
MUL_4327|M.ulcerans_Agy99 TPSEQFLQHYG--APPITIGPLYQPRTIELCASGDPVCSG-GNDAA---A
TH_1243|M.thermoresistible__bu QPSSALLQRYG--APPIAIGSVYQDKTLELCTEGDTICNG-VADVMPTFA
** :: **: :* * :*:::* * :*. : :
MAB_3272c|M.abscessus_ATCC_199 HGSYGDNGMTSQAADFAARQIN-----SPTDTVSAAG
Mvan_5804|M.vanbaalenii_PYR-1 HGGYALTGMTDRAAEFAVRNMPRHGSEQPVDLAAGPR
MSMEG_6354|M.smegmatis_MC2_155 HNLYATNGMVQQAADYVAARVL------PQ-------
Mb1788|M.bovis_AF2122/97 HNGYADDGMVEQAAVFAAGRLG---------------
Rv1758|M.tuberculosis_H37Rv HNGYADDGMVEQAAVFAAGRLG---------------
Mflv_4439|M.gilvum_PYR-GCK HARYISDGLVVQAADFAVGKLAE----TPAESGGAPA
MAV_2961|M.avium_104 HRQYVEAGMVDQAVDFTTDRV----------------
MMAR_5251|M.marinum_M HALYAVNGMTGQGADFAAHHL----------------
MUL_4327|M.ulcerans_Agy99 HALYAVNGMTGQGADFAAHHL----------------
TH_1243|M.thermoresistible__bu HVTYTWNGMPAEGAAFAADRL----------------
* * *: ... :.. .: