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MNIFSRWLAVAASVVAVTGGLPLAAAPAYAAPCPDVEVVFARGTFEPPGIGATGQAFVDSLRSRAGGRTV DVYAVNYPASFDFATAADGVIDASNRVVTMAANCPDTQLVLGGFSQGAAVAAYITEDTIPEGYTPPPGMT GPMPPSVADNVAAVALFGKPSSGFLQMIYTGAPPINVGSRYAAKTLDLCIPEDPVCSPTGRDNAAHGGYA LTGMTDRAAEFAVRNMPRHGSEQPVDLAAGPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | - | 100% (242) | cutinase |
| M. vanbaalenii PYR-1 | Mvan_5793 | - | 5e-56 | 50.43% (232) | cutinase |
| M. vanbaalenii PYR-1 | Mvan_3105 | - | 2e-50 | 50.90% (222) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 8e-56 | 53.24% (216) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 2e-59 | 53.98% (226) | cutinase |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 4e-49 | 46.22% (225) | cutinase precursor CFP21 |
| M. leprae Br4923 | MLBr_00099 | - | 3e-08 | 27.52% (218) | hypothetical protein MLBr_00099 |
| M. abscessus ATCC 19977 | MAB_3272c | - | 2e-73 | 67.02% (188) | cutinase Cut1 |
| M. marinum M | MMAR_5251 | cut5 | 1e-55 | 50.87% (230) | cutinase, Cut5 |
| M. avium 104 | MAV_2961 | - | 1e-59 | 58.08% (198) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_6354 | - | 2e-72 | 59.01% (222) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_0238 | - | 6e-53 | 52.09% (215) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 2e-55 | 50.85% (234) | cutinase, Cut5 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5804|M.vanbaalenii_PYR-1 ---------------------MNIFSRWLAVAASVVAVTG-----GLPLA
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6354|M.smegmatis_MC2_155 -------------------MFKSTLSRFIPAVSAALLTAG-----LVPGT
Mflv_4439|M.gilvum_PYR-GCK --------------MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTP-
MAV_2961|M.avium_104 ---------------------------MLSPFWALLLG------PALV--
Mb1788|M.bovis_AF2122/97 ----------------------------MVTTWALLFAP----VPAAS--
MMAR_5251|M.marinum_M ---------------------------MRNATWTRRLAVG--AATAVTAL
MUL_4327|M.ulcerans_Agy99 ---------------------------MRNATWTRRLAVG--AATAVTAL
TH_0238|M.thermoresistible__bu ------------------------LSRIGSAVGAALTTASLITGTVITST
Rv1984c|M.tuberculosis_H37Rv -----------------------MTPRSLVRIVGVVVATT----LALVSA
MLBr_00099|M.leprae_Br4923 MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLPPGV
Mvan_5804|M.vanbaalenii_PYR-1 AAPAYAAP----------------CPDVEVVFARGTFE------PPGIGA
MAB_3272c|M.abscessus_ATCC_199 ------------------------------MFARGTFE------PPGVGG
MSMEG_6354|M.smegmatis_MC2_155 AGTANAEPPI--------EGAAPPCPDVEVVFARGTFE------PPGVGF
Mflv_4439|M.gilvum_PYR-GCK -APGPAPPPIAAPAPEPLAAPVAGCPDVEIVFARGTTE------APGLGA
MAV_2961|M.avium_104 ---GTAAP-----------AAADSCPDVEVVFARGTSE------PPGVGR
Mb1788|M.bovis_AF2122/97 --ADPPDP----------TVSDGACPDVEVVFARGTGE------PPGVGG
MMAR_5251|M.marinum_M VGWGIRVP----------FAAAEPCPDVEVLFARGTGE------PPGIGG
MUL_4327|M.ulcerans_Agy99 VGGGIRVP----------FVAAEPCPDVEVLFARGTGE------PPGIGG
TH_0238|M.thermoresistible__bu VVAGTAVP----------AAAAQPCPDVQVVFARGTGE------PPGVGP
Rv1984c|M.tuberculosis_H37Rv PAGGRAAH-------------ADPCSDIAVVFARGTHQ------ASGLGD
MLBr_00099|M.leprae_Br4923 LPIPSTAPHPRKPRP---AFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQ
:.. ** : . .
Mvan_5804|M.vanbaalenii_PYR-1 TGQAFVDSLRSRAGGRT----VDVYAVNYPASFDFATA-----------A
MAB_3272c|M.abscessus_ATCC_199 TGESFVNALRARTKGKS----VEVYPVEYPASLAFATA-----------A
MSMEG_6354|M.smegmatis_MC2_155 VGQAFVDALRGRLGDKS----VDVYAVNYPASLDFQRA-----------A
Mflv_4439|M.gilvum_PYR-GCK MGQAFVEDLRSRLGGKT----VGVYAVDYPASPDFPTA-----------V
MAV_2961|M.avium_104 IGQSFVDTLRSRLGTKS----VGVYPVNYPATTDFPTA-----------A
Mb1788|M.bovis_AF2122/97 IGEDFIDALRSKIGEKS----MGVYGVDYPATTDFPTA-----------M
MMAR_5251|M.marinum_M IGGSFVAALRSDIGAKS----LAVYAVDYPASSDFSSSD-----FPRTVI
MUL_4327|M.ulcerans_Agy99 IGGSFVAALRSDIGAKS----SAVYAIDYPASSDFSSSD-----FPRTVI
TH_0238|M.thermoresistible__bu TGQAFIDALRPRVGDRS----LDVYAVNYPAIDVWNTG-----------I
Rv1984c|M.tuberculosis_H37Rv VGEAFVDSLTSQVGGRS----IGVYAVNYPASDDYRAS----------AS
MLBr_00099|M.leprae_Br4923 FPDALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQMTYNDSRA
:: : .* : *.* .
Mvan_5804|M.vanbaalenii_PYR-1 DGVIDASNRVVTMAANCPDTQLVLGGFSQGAAVAAYITEDT---------
MAB_3272c|M.abscessus_ATCC_199 DGVIDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYTTADA---------
MSMEG_6354|M.smegmatis_MC2_155 DGIVDASRKVEQTAATCPSTKTVIGGFSQGAAVAAYLTADS---------
Mflv_4439|M.gilvum_PYR-GCK EGIADASTHVQQIAMNCPDTKLVLGGYSQGAAVMGFVTTEL---------
MAV_2961|M.avium_104 DGISDAGAHVQQMAANCPRTKMVLGGYSQGAAVMGFVTESA---------
Mb1788|M.bovis_AF2122/97 AGIYDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFVTAAA---------
MMAR_5251|M.marinum_M EGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSAS---------
MUL_4327|M.ulcerans_Agy99 DGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSAS---------
TH_0238|M.thermoresistible__bu DGIRDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAE---------
Rv1984c|M.tuberculosis_H37Rv NGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTS-----------
MLBr_00099|M.leprae_Br4923 EGTRAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDD
* .: ** : *: *:****.: *
Mvan_5804|M.vanbaalenii_PYR-1 -------IPEGYTPPPGMTGPMPPSVADNVAAVALFGKPSSGFLQMIYTG
MAB_3272c|M.abscessus_ATCC_199 -------VPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQRIDNT
MSMEG_6354|M.smegmatis_MC2_155 -------VPANFVLPDGITGPMPDDVAKHVTAVTLFGKPSNGFINTVQST
Mflv_4439|M.gilvum_PYR-GCK -------IPDG-VSLSEVPAPMPPDIADHVAAVALLGAPSDRFMDMIK--
MAV_2961|M.avium_104 -------VPDG-VQLVQSLQPMPAAVANHVAAVALFGKPSAQFMSIIN--
Mb1788|M.bovis_AF2122/97 -------IPDG-APL-DAPRPMPPEVADHVAAVTLFGMPSVAFMHSIG--
MMAR_5251|M.marinum_M -------VPPG-VPAAAVPKPMAPDIADHVAAVTLFGTPSEQFLQHYG--
MUL_4327|M.ulcerans_Agy99 -------VPPG-VPAAAVPKPMAPDIADYVAAVTLFGTPSEQFLQHYG--
TH_0238|M.thermoresistible__bu -------VPAG-VDPATVPKPLDPDIAEHVAAVVLFGMPNARAMNFLG--
Rv1984c|M.tuberculosis_H37Rv --------------------AMPPAVADHVAAVALFGEPSSGFSSMLWGG
MLBr_00099|M.leprae_Br4923 DLVLGVTLIADGRRQQGVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTG
: . : *.* *
Mvan_5804|M.vanbaalenii_PYR-1 APPINVGSRYAAKTLDLCIPEDPVCSPT------------------GRDN
MAB_3272c|M.abscessus_ATCC_199 APPINIGHLYVAKTMDMCVPEDPICSPD------------------GSDN
MSMEG_6354|M.smegmatis_MC2_155 APPINIGHLYTDKTVDLCIETDPVCSPT------------------GSDG
Mflv_4439|M.gilvum_PYR-GCK QPPVTIGALYQPKTLELCVPGDFVCSP-------------------GNDL
MAV_2961|M.avium_104 EPPVTIGPLYAAKTIELCVPGDPICSG-------------------AVNP
Mb1788|M.bovis_AF2122/97 APPIVIGPLYAEKTIQLCAPGDPVCSS-------------------GGNW
MMAR_5251|M.marinum_M APPITIGPLYQPRTVELCASGDPVCSG-------------------GNDA
MUL_4327|M.ulcerans_Agy99 APPITIGPLYQPRTIELCASGDPVCSG-------------------GNDA
TH_0238|M.thermoresistible__bu TPPVVIGPLYEDKTVKLCAVDDPVCSN-------------------GMNF
Rv1984c|M.tuberculosis_H37Rv GSLPTIGPLYSSKTINLCAPDDPICTG-------------------GGNI
MLBr_00099|M.leprae_Br4923 ARPGGFGVLHS-RTNEICAPGDLICAAPAEAFSVANLPATLNTLASGAGQ
.* : :* .:* * :*: . .
Mvan_5804|M.vanbaalenii_PYR-1 AAHGGYALTG-MTDRAAEFAVRNMPRHGSEQPVDLAAGPR---
MAB_3272c|M.abscessus_ATCC_199 AAHGSYGDNG-MTSQAADFAARQIN-----SPTDTVSAAG---
MSMEG_6354|M.smegmatis_MC2_155 ASHNLYATNG-MVQQAADYVAARVL------PQ----------
Mflv_4439|M.gilvum_PYR-GCK GAHARYISDG-LVVQAADFAVGKLAETPAESGGAPA-------
MAV_2961|M.avium_104 AAHRQYVEAG-MVDQAVDFTTDRV-------------------
Mb1788|M.bovis_AF2122/97 AAHNGYADDG-MVEQAAVFAAGRLG------------------
MMAR_5251|M.marinum_M AAHALYAVNG-MTGQGADFAAHHL-------------------
MUL_4327|M.ulcerans_Agy99 AAHALYAVNG-MTGQGADFAAHHL-------------------
TH_0238|M.thermoresistible__bu AAHNTYATNAAMVDQGAAFAADRLGVASDKPLPTPSSGQNFGN
Rv1984c|M.tuberculosis_H37Rv MAHVSYVQSG-MTSQAATFAANRLDHAG---------------
MLBr_00099|M.leprae_Br4923 PIHAMYATAQFWDLDGAPATVWTLNWVHRLIEGAPHPKHG---
* * .. .. :