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SASKRAGKANVVTKMARATVFPALAVAATGFGMLAGPAATASAADNACADVEVVFARGTFEAPGIGATGQ AFVDALKDRLPGKSVDVYAVNYPASLDFAQAAAGIADTSNRIQTVAAQCPTTDIVLGGYSQGAAVAGYTT TSSLPAGYTLPAGINGPMPAATASHVAAVVLFGTPKDWVVNLADRNAPPITIGQSYVPKTLQLCATGDPV CFPGGLDRAAHSSYKSNGMAVQAADFAARQVTGGSATVVQAAGAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4465 | - | - | 100% (256) | cutinase |
| M. smegmatis MC2 155 | MSMEG_2474 | - | 3e-81 | 64.98% (237) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_6354 | - | 7e-67 | 54.24% (236) | serine esterase, cutinase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 6e-52 | 50.23% (217) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 1e-56 | 53.15% (222) | cutinase |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 3e-43 | 45.16% (217) | cutinase precursor CFP21 |
| M. leprae Br4923 | MLBr_00099 | - | 7e-05 | 25.00% (204) | hypothetical protein MLBr_00099 |
| M. abscessus ATCC 19977 | MAB_3272c | - | 5e-65 | 59.50% (200) | cutinase Cut1 |
| M. marinum M | MMAR_5251 | cut5 | 2e-52 | 51.91% (235) | cutinase, Cut5 |
| M. avium 104 | MAV_2961 | - | 3e-55 | 52.34% (214) | cutinase Cut3 |
| M. thermoresistible (build 8) | TH_0238 | - | 1e-47 | 45.92% (233) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 4e-51 | 50.64% (235) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | 4e-67 | 56.22% (233) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5804|M.vanbaalenii_PYR-1 -------------------------------MNIFSRWLAVAASVVAVTG
MSMEG_4465|M.smegmatis_MC2_155 -------------------MSASKRAGKANVVTKMARATVFPALAVAATG
Mb1788|M.bovis_AF2122/97 ---------------------------MVTTWALLFA-------------
MAV_2961|M.avium_104 --------------------------MLSPFWALLLG-------------
Mflv_4439|M.gilvum_PYR-GCK -------------MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAP
MMAR_5251|M.marinum_M -------------------------MRNATWTRRLAVG--------AATA
MUL_4327|M.ulcerans_Agy99 -------------------------MRNATWTRRLAVG--------AATA
TH_0238|M.thermoresistible__bu ----------------------LSRIGSAVGAALTTASL------ITGTV
Rv1984c|M.tuberculosis_H37Rv ----------------------MTPRSLVRIVGVVVATT-----------
MLBr_00099|M.leprae_Br4923 MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLPPGV
MAB_3272c|M.abscessus_ATCC_199 ---------------------------MFARGTFEPPGVG----------
Mvan_5804|M.vanbaalenii_PYR-1 G----LPLAAAP----AYAAPCPDVEVVFARGTFEPPGIG----------
MSMEG_4465|M.smegmatis_MC2_155 FGMLAGPAATAS----AADNACADVEVVFARGTFEAPGIG----------
Mb1788|M.bovis_AF2122/97 ---PVPAASADPPDPTVSDGACPDVEVVFARGTGEPPGVG----------
MAV_2961|M.avium_104 ---PALVGTAAP----AAADSCPDVEVVFARGTSEPPGVG----------
Mflv_4439|M.gilvum_PYR-GCK GPAPPPIAAPAPEPLAAPVAGCPDVEIVFARGTTEAPGLG----------
MMAR_5251|M.marinum_M VTALVGWGIRVP---FAAAEPCPDVEVLFARGTGEPPGIG----------
MUL_4327|M.ulcerans_Agy99 VTALVGGGIRVP---FVAAEPCPDVEVLFARGTGEPPGIG----------
TH_0238|M.thermoresistible__bu ITSTVVAGTAVP---AAAAQPCPDVQVVFARGTGEPPGVG----------
Rv1984c|M.tuberculosis_H37Rv ---LALVSAPAG-GRAAHADPCSDIAVVFARGTHQASGLG----------
MLBr_00099|M.leprae_Br4923 LPIPSTAPHPRKPRPAFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQFPD
:.. ** :.. .
MAB_3272c|M.abscessus_ATCC_199 GTGESFVNALRARTKGKSVEVYPVEYPASLAFATA-----------ADGV
Mvan_5804|M.vanbaalenii_PYR-1 ATGQAFVDSLRSRAGGRTVDVYAVNYPASFDFATA-----------ADGV
MSMEG_4465|M.smegmatis_MC2_155 ATGQAFVDALKDRLPGKSVDVYAVNYPASLDFAQA-----------AAGI
Mb1788|M.bovis_AF2122/97 GIGEDFIDALRSKIGEKSMGVYGVDYPATTDFPTA-----------MAGI
MAV_2961|M.avium_104 RIGQSFVDTLRSRLGTKSVGVYPVNYPATTDFPTA-----------ADGI
Mflv_4439|M.gilvum_PYR-GCK AMGQAFVEDLRSRLGGKTVGVYAVDYPASPDFPTA-----------VEGI
MMAR_5251|M.marinum_M GIGGSFVAALRSDIGAKSLAVYAVDYPASSDFSSSD-----FPRTVIEGI
MUL_4327|M.ulcerans_Agy99 GIGGSFVAALRSDIGAKSSAVYAIDYPASSDFSSSD-----FPRTVIDGI
TH_0238|M.thermoresistible__bu PTGQAFIDALRPRVGDRSLDVYAVNYPAIDVWNTG-----------IDGI
Rv1984c|M.tuberculosis_H37Rv DVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYRAS----------ASNGS
MLBr_00099|M.leprae_Br4923 ALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQMTYNDSRAEGT
: .* : *.* . *
MAB_3272c|M.abscessus_ATCC_199 IDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYTTADA------------
Mvan_5804|M.vanbaalenii_PYR-1 IDASNRVVTMAANCPDTQLVLGGFSQGAAVAAYITEDT------------
MSMEG_4465|M.smegmatis_MC2_155 ADTSNRIQTVAAQCPTTDIVLGGYSQGAAVAGYTTTSS------------
Mb1788|M.bovis_AF2122/97 YDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFVTAAA------------
MAV_2961|M.avium_104 SDAGAHVQQMAANCPRTKMVLGGYSQGAAVMGFVTESA------------
Mflv_4439|M.gilvum_PYR-GCK ADASTHVQQIAMNCPDTKLVLGGYSQGAAVMGFVTTEL------------
MMAR_5251|M.marinum_M RDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSAS------------
MUL_4327|M.ulcerans_Agy99 RDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSAS------------
TH_0238|M.thermoresistible__bu RDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAE------------
Rv1984c|M.tuberculosis_H37Rv DDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTS--------------
MLBr_00099|M.leprae_Br4923 RAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDDDLV
.: ** : *: *:****.: *
MAB_3272c|M.abscessus_ATCC_199 ----VPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQRIDNTAPP
Mvan_5804|M.vanbaalenii_PYR-1 ----IPEGYTPPPGMTGPMPPSVADNVAAVALFGKPSSGFLQMIYTGAPP
MSMEG_4465|M.smegmatis_MC2_155 ----LPAGYTLPAGINGPMPAATASHVAAVVLFGTPKDWVVNLADRNAPP
Mb1788|M.bovis_AF2122/97 ----IPDGAPLDAP--RPMPPEVADHVAAVTLFGMPSVAFMHSIG--APP
MAV_2961|M.avium_104 ----VPDGVQLVQSL-QPMPAAVANHVAAVALFGKPSAQFMSIIN--EPP
Mflv_4439|M.gilvum_PYR-GCK ----IPDGVSLSEVP-APMPPDIADHVAAVALLGAPSDRFMDMIK--QPP
MMAR_5251|M.marinum_M ----VPPGVP-AAAVPKPMAPDIADHVAAVTLFGTPSEQFLQHYG--APP
MUL_4327|M.ulcerans_Agy99 ----VPPGVP-AAAVPKPMAPDIADYVAAVTLFGTPSEQFLQHYG--APP
TH_0238|M.thermoresistible__bu ----VPAGVD-PATVPKPLDPDIAEHVAAVVLFGMPNARAMNFLG--TPP
Rv1984c|M.tuberculosis_H37Rv -----------------AMPPAVADHVAAVALFGEPSSGFSSMLWGGGSL
MLBr_00099|M.leprae_Br4923 LGVTLIADGRRQQGVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTGARP
: . . * *.* *
MAB_3272c|M.abscessus_ATCC_199 INIGHLYVAKTMDMCVPEDPICSPD------------------GSDNAAH
Mvan_5804|M.vanbaalenii_PYR-1 INVGSRYAAKTLDLCIPEDPVCSPT------------------GRDNAAH
MSMEG_4465|M.smegmatis_MC2_155 ITIGQSYVPKTLQLCATGDPVCFPG------------------GLDRAAH
Mb1788|M.bovis_AF2122/97 IVIGPLYAEKTIQLCAPGDPVCSS-------------------GGNWAAH
MAV_2961|M.avium_104 VTIGPLYAAKTIELCVPGDPICSG-------------------AVNPAAH
Mflv_4439|M.gilvum_PYR-GCK VTIGALYQPKTLELCVPGDFVCSP-------------------GNDLGAH
MMAR_5251|M.marinum_M ITIGPLYQPRTVELCASGDPVCSG-------------------GNDAAAH
MUL_4327|M.ulcerans_Agy99 ITIGPLYQPRTIELCASGDPVCSG-------------------GNDAAAH
TH_0238|M.thermoresistible__bu VVIGPLYEDKTVKLCAVDDPVCSN-------------------GMNFAAH
Rv1984c|M.tuberculosis_H37Rv PTIGPLYSSKTINLCAPDDPICTG-------------------GGNIMAH
MLBr_00099|M.leprae_Br4923 GGFGVLHS-RTNEICAPGDLICAAPAEAFSVANLPATLNTLASGAGQPIH
.* : :* .:* * :* . . *
MAB_3272c|M.abscessus_ATCC_199 GSYGDNG-MTSQAADFAARQIN-----SPTDTVSAAG---
Mvan_5804|M.vanbaalenii_PYR-1 GGYALTG-MTDRAAEFAVRNMPRHGSEQPVDLAAGPR---
MSMEG_4465|M.smegmatis_MC2_155 SSYKSNG-MAVQAADFAARQVTG--GSATVVQAAGAA---
Mb1788|M.bovis_AF2122/97 NGYADDG-MVEQAAVFAAGRLG------------------
MAV_2961|M.avium_104 RQYVEAG-MVDQAVDFTTDRV-------------------
Mflv_4439|M.gilvum_PYR-GCK ARYISDG-LVVQAADFAVGKLAE----TPAESGGAPA---
MMAR_5251|M.marinum_M ALYAVNG-MTGQGADFAAHHL-------------------
MUL_4327|M.ulcerans_Agy99 ALYAVNG-MTGQGADFAAHHL-------------------
TH_0238|M.thermoresistible__bu NTYATNAAMVDQGAAFAADRLGVASDKPLPTPSSGQNFGN
Rv1984c|M.tuberculosis_H37Rv VSYVQSG-MTSQAATFAANRLDHAG---------------
MLBr_00099|M.leprae_Br4923 AMYATAQFWDLDGAPATVWTLNWVHRLIEGAPHPKHG---
* .. :. :