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MNNDHATTRPSIVRTAFVGVTLAALGLVMGVVGLQAAGTASAAPSSPCADVEVVFARGTFEAPGVGDTGQ AFVNALGAQLPGKNIAVYAVNYPASLDFNDAALGVADAAREVQAVAAGCPDTQIVLGGYSQGAAVAGYTT SGAVPAGYALPAGITGPMPPAIAPHVAAVVLFGTPSPFFLGLVDHSAPPLVIGPAYAAKTLQLCNTGDPV CYPGGLDRAAHSAYKSNGMADQAAQFVVDHLGATSTATPAQVVSATTHP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2474 | - | - | 100% (259) | cutinase Cut3 |
| M. smegmatis MC2 155 | MSMEG_4465 | - | 3e-81 | 64.98% (237) | cutinase |
| M. smegmatis MC2 155 | MSMEG_6354 | - | 5e-64 | 55.45% (220) | serine esterase, cutinase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 1e-53 | 52.15% (209) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 1e-54 | 54.19% (203) | cutinase |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 5e-46 | 45.19% (239) | cutinase precursor CFP21 |
| M. leprae Br4923 | MLBr_00099 | - | 3e-08 | 28.43% (204) | hypothetical protein MLBr_00099 |
| M. abscessus ATCC 19977 | MAB_3272c | - | 1e-60 | 57.43% (202) | cutinase Cut1 |
| M. marinum M | MMAR_5251 | cut5 | 9e-54 | 50.67% (225) | cutinase, Cut5 |
| M. avium 104 | MAV_0369 | - | 2e-59 | 52.97% (236) | serine esterase cutinase |
| M. thermoresistible (build 8) | TH_0238 | - | 3e-53 | 50.00% (232) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 9e-53 | 49.15% (234) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | 1e-65 | 53.02% (232) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5804|M.vanbaalenii_PYR-1 ----------------MN----------IFSRWLAVAASVVAVTGGLP--
MSMEG_2474|M.smegmatis_MC2_155 ----------------MNNDHATTRPSIVRTAFVGVTLAALGLVMGVVGL
Mb1788|M.bovis_AF2122/97 ---------------------------MVTTWALLFAP--------VPAA
Mflv_4439|M.gilvum_PYR-GCK -------------MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAP
MMAR_5251|M.marinum_M ----------------------------MRNATWTRRLAVGAATAVTALV
MUL_4327|M.ulcerans_Agy99 ----------------------------MRNATWTRRLAVGAATAVTALV
MAV_0369|M.avium_104 -------------------------------MSFQVRAALTVLTAAAALC
TH_0238|M.thermoresistible__bu --------------------------LSRIGSAVGAALTTASLITGTVIT
Rv1984c|M.tuberculosis_H37Rv ----------------------------MTPRSLVRIVGVVVATTLALVS
MLBr_00099|M.leprae_Br4923 MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLPPGV
MAB_3272c|M.abscessus_ATCC_199 ---------------------------MFARGTFEPPGVG----------
Mvan_5804|M.vanbaalenii_PYR-1 LAAAP--------AYAAP---CPDVEVVFARGTFEPPGIG----------
MSMEG_2474|M.smegmatis_MC2_155 QAAGT--------ASAAPSSPCADVEVVFARGTFEAPGVG----------
Mb1788|M.bovis_AF2122/97 SADPP-------DPTVSDGA-CPDVEVVFARGTGEPPGVG----------
Mflv_4439|M.gilvum_PYR-GCK GPAPPPIAAPAPEPLAAPVAGCPDVEIVFARGTTEAPGLG----------
MMAR_5251|M.marinum_M GWGIR--------VPFAAAEPCPDVEVLFARGTGEPPGIG----------
MUL_4327|M.ulcerans_Agy99 GGGIR--------VPFVAAEPCPDVEVLFARGTGEPPGIG----------
MAV_0369|M.avium_104 VAPMPG-------APAAGADPCPDVEVVFARGSGEPPGIG----------
TH_0238|M.thermoresistible__bu STVVAG-----TAVPAAAAQPCPDVQVVFARGTGEPPGVG----------
Rv1984c|M.tuberculosis_H37Rv APAGG---------RAAHADPCSDIAVVFARGTHQASGLG----------
MLBr_00099|M.leprae_Br4923 LPIPSTAPHPRKPRPAFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQFPD
:.. *: :.. .
MAB_3272c|M.abscessus_ATCC_199 GTGESFVNALRARTKGKSVEVYPVEYPASLAFA-----------TAADGV
Mvan_5804|M.vanbaalenii_PYR-1 ATGQAFVDSLRSRAGGRTVDVYAVNYPASFDFA-----------TAADGV
MSMEG_2474|M.smegmatis_MC2_155 DTGQAFVNALGAQLPGKNIAVYAVNYPASLDFN-----------DAALGV
Mb1788|M.bovis_AF2122/97 GIGEDFIDALRSKIGEKSMGVYGVDYPATTDFP-----------TAMAGI
Mflv_4439|M.gilvum_PYR-GCK AMGQAFVEDLRSRLGGKTVGVYAVDYPASPDFP-----------TAVEGI
MMAR_5251|M.marinum_M GIGGSFVAALRSDIGAKSLAVYAVDYPASSDFSSS-----DFPRTVIEGI
MUL_4327|M.ulcerans_Agy99 GIGGSFVAALRSDIGAKSSAVYAIDYPASSDFSSS-----DFPRTVIDGI
MAV_0369|M.avium_104 GIGQPFVDALRSQIGSRSLAVYAVKYPASTDFSNP-----DFPATVIDGI
TH_0238|M.thermoresistible__bu PTGQAFIDALRPRVGDRSLDVYAVNYPAIDVWN-----------TGIDGI
Rv1984c|M.tuberculosis_H37Rv DVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYR----------ASASNGS
MLBr_00099|M.leprae_Br4923 ALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQMTYNDSRAEGT
: .* : *.* *
MAB_3272c|M.abscessus_ATCC_199 IDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYTTADAVPPGFELPE---
Mvan_5804|M.vanbaalenii_PYR-1 IDASNRVVTMAANCPDTQLVLGGFSQGAAVAAYITEDTIPEGYTPPP---
MSMEG_2474|M.smegmatis_MC2_155 ADAAREVQAVAAGCPDTQIVLGGYSQGAAVAGYTTSGAVPAGYALPA---
Mb1788|M.bovis_AF2122/97 YDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFVTAAAIPDGAPL-----
Mflv_4439|M.gilvum_PYR-GCK ADASTHVQQIAMNCPDTKLVLGGYSQGAAVMGFVTTELIPDGVSLS----
MMAR_5251|M.marinum_M RDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSASVPPGVPAA----
MUL_4327|M.ulcerans_Agy99 RDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSASVPPGVPAA----
MAV_0369|M.avium_104 RDASSHLESMVASCPNTREVLGGYSQGAAVAGYTTSAVVPPGVPAS----
TH_0238|M.thermoresistible__bu RDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAEVPAGVDPA----
Rv1984c|M.tuberculosis_H37Rv DDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTS--------------
MLBr_00099|M.leprae_Br4923 RAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDDDLV
.: ** : *: *:****.: *
MAB_3272c|M.abscessus_ATCC_199 -------------GITGPMPAEVADHVAAVALFGKPSSGFLQRIDNTAPP
Mvan_5804|M.vanbaalenii_PYR-1 -------------GMTGPMPPSVADNVAAVALFGKPSSGFLQMIYTGAPP
MSMEG_2474|M.smegmatis_MC2_155 -------------GITGPMPPAIAPHVAAVVLFGTPSPFFLGLVDHSAPP
Mb1788|M.bovis_AF2122/97 -------------DAPRPMPPEVADHVAAVTLFGMPSVAFMHSIG--APP
Mflv_4439|M.gilvum_PYR-GCK -------------EVPAPMPPDIADHVAAVALLGAPSDRFMDMIK--QPP
MMAR_5251|M.marinum_M -------------AVPKPMAPDIADHVAAVTLFGTPSEQFLQHYG--APP
MUL_4327|M.ulcerans_Agy99 -------------AVPKPMAPDIADYVAAVTLFGTPSEQFLQHYG--APP
MAV_0369|M.avium_104 -------------AVPPPMPPEVAKHVAAVTLFGTPSGQFLQKYH--APP
TH_0238|M.thermoresistible__bu -------------TVPKPLDPDIAEHVAAVVLFGMPNARAMNFLG--TPP
Rv1984c|M.tuberculosis_H37Rv -----------------AMPPAVADHVAAVALFGEPSSGFSSMLWGGGSL
MLBr_00099|M.leprae_Br4923 LGVTLIADGRRQQGVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTGARP
: . . * *.* *
MAB_3272c|M.abscessus_ATCC_199 INIGHLYVAKTMDMCVPEDPICS------------------PDGSDNAAH
Mvan_5804|M.vanbaalenii_PYR-1 INVGSRYAAKTLDLCIPEDPVCS------------------PTGRDNAAH
MSMEG_2474|M.smegmatis_MC2_155 LVIGPAYAAKTLQLCNTGDPVCY------------------PGGLDRAAH
Mb1788|M.bovis_AF2122/97 IVIGPLYAEKTIQLCAPGDPVCS------------------S-GGNWAAH
Mflv_4439|M.gilvum_PYR-GCK VTIGALYQPKTLELCVPGDFVCS------------------P-GNDLGAH
MMAR_5251|M.marinum_M ITIGPLYQPRTVELCASGDPVCS-------------------GGNDAAAH
MUL_4327|M.ulcerans_Agy99 ITIGPLYQPRTIELCASGDPVCS-------------------GGNDAAAH
MAV_0369|M.avium_104 LAIGPLYQPKTLQLCAVGDPICGT-----------------GGGNDLAAH
TH_0238|M.thermoresistible__bu VVIGPLYEDKTVKLCAVDDPVCS-------------------NGMNFAAH
Rv1984c|M.tuberculosis_H37Rv PTIGPLYSSKTINLCAPDDPICT-------------------GGGNIMAH
MLBr_00099|M.leprae_Br4923 GGFG-VLHSRTNEICAPGDLICAAPAEAFSVANLPATLNTLASGAGQPIH
.* :* .:* * :* * . *
MAB_3272c|M.abscessus_ATCC_199 GSYGDNG-MTSQAADFAARQIN-----SPTDTVSAAG---
Mvan_5804|M.vanbaalenii_PYR-1 GGYALTG-MTDRAAEFAVRNMPRHGSEQPVDLAAGPR---
MSMEG_2474|M.smegmatis_MC2_155 SAYKSNG-MADQAAQFVVDHLGATSTATPAQVVSATTHP-
Mb1788|M.bovis_AF2122/97 NGYADDG-MVEQAAVFAAGRLG------------------
Mflv_4439|M.gilvum_PYR-GCK ARYISDG-LVVQAADFAVGKLAE----TPAESGGAPA---
MMAR_5251|M.marinum_M ALYAVNG-MTGQGADFAAHHL-------------------
MUL_4327|M.ulcerans_Agy99 ALYAVNG-MTGQGADFAAHHL-------------------
MAV_0369|M.avium_104 TSYPVNG-MTNQAAQYVFSHL-------------------
TH_0238|M.thermoresistible__bu NTYATNAAMVDQGAAFAADRLGVASDKPLPTPSSGQNFGN
Rv1984c|M.tuberculosis_H37Rv VSYVQSG-MTSQAATFAANRLDHAG---------------
MLBr_00099|M.leprae_Br4923 AMYATAQFWDLDGAPATVWTLNWVHRLIEGAPHPKHG---
* .* . :