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MSGRVAGKRVLVTGAARGMGRSHAVRLAEEGADLILLDICESIPEIEYPLATEDELAETVRLVEEHGRHA LAHVVDVRDGEALSAAVTDAVAQLGGLDASVANAGVLTAGTWDTTTSEQWRTVVDVNLIGTWNTCAAALP HLVERGGSVINISSAAGVKGSPLHTPYTASKHGVVGLSRALANELAAVGVRVNTVHPTGVETGMRPDSLH TLLVEKRPDLAPIFANAMPIVMAEAIDISNAVLYLVSDESRYVTGLEFKVDAGVTLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5813 | - | - | 100% (267) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 2e-63 | 50.00% (286) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6031 | - | 7e-63 | 50.00% (284) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 1e-58 | 47.35% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1905 | - | 1e-124 | 79.40% (267) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 1e-58 | 47.35% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 2e-25 | 37.50% (200) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3081 | - | 4e-60 | 45.96% (272) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 3e-62 | 49.30% (284) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3551 | - | 1e-111 | 72.28% (267) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3757 | - | 3e-62 | 48.88% (268) | PUTATIVE carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_3392 | fabG | 1e-56 | 44.49% (272) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_3395 | - | 1e-127 | 82.71% (266) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ----MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS
Rv2750|M.tuberculosis_H37Rv ----MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS
MUL_3392|M.ulcerans_Agy99 -MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS
MAB_3081|M.abscessus_ATCC_1997 ------MGKLDGKVAFITGAARGQGRAHAIKLASEGASIIAVDICAQIPS
TH_3757|M.thermoresistible__bu ------MGKLDGKVAFITGAARGQGRAHAVRLAEEGADVIAVDVCEQYAT
MMAR_4754|M.marinum_M -MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVE
MSMEG_5813|M.smegmatis_MC2_155 -----MSGRVAGKRVLVTGAARGMGRSHAVRLAEEGADLILLDICESIPE
Mvan_3395|M.vanbaalenii_PYR-1 ----MSAGRVAGKRVLITGAARGMGRSHAVRLAGEGADLILVDICESLPE
Mflv_1905|M.gilvum_PYR-GCK -----MSGRVEGKRVLITGAARGMGRSHAVRLAQEGADLILVDICESLPE
MAV_3551|M.avium_104 MATDDATGRVAGKRVLITGAARGMGRSHAVRLAEQGADCILVDICCTPTG
MLBr_01740|M.leprae_Br4923 --MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR------
. *: ::**** * **: *::** **. *
Mb2771|M.bovis_AF2122/97 -VPYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGLDE
Rv2750|M.tuberculosis_H37Rv -VPYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGLDE
MUL_3392|M.ulcerans_Agy99 -VPYPLGTAEELATTVKLVEDTGARIVAS-QADVRDREALAAALQAGIDE
MAB_3081|M.abscessus_ATCC_1997 -VEYPMATTEDLDLTVKEVDALGRAISAH-ETDVRDREALQAAFDAGVHD
TH_3757|M.thermoresistible__bu -VVYQMSRPEDLAETVRQVETLGRRIVAR-EVDVCDLAGLQKAFDDGAAQ
MMAR_4754|M.marinum_M NTTIPASTPEDLAETADLVKGHNRRIFTA-EADVRDYDALKAAVDAGVDE
MSMEG_5813|M.smegmatis_MC2_155 -IEYPLATEDELAETVRLVEEHGRHALAH-VVDVRDGEALSAAVTDAVAQ
Mvan_3395|M.vanbaalenii_PYR-1 -IEYPLASPDDLAETARLVEDIGRRAVTH-VVDVRDGAALATAVDDGVAR
Mflv_1905|M.gilvum_PYR-GCK -VEYPLAAVEELADTAELVAQHGRRAVTH-VVDVRDEQALSAAVDDGVAR
MAV_3551|M.avium_104 -LDYPLATEEDLNETVRLVEKHGRRAVPK-IVDVRDEAAMKAAVDAAVDE
MLBr_01740|M.leprae_Br4923 -------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHAR
: * *. . . *: * :
Mb2771|M.bovis_AF2122/97 FGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIPTL
Rv2750|M.tuberculosis_H37Rv FGRLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIPTL
MUL_3392|M.ulcerans_Agy99 LGQVDIVVANAGIAPMQ-----SGDDGWRDVIDVNLSGAYYTVEVAIPTM
MAB_3081|M.abscessus_ATCC_1997 LGPVDIVVANAGIATLTP---ECGDDGWRDVLDVNLTGVYHTIEVARPSM
TH_3757|M.thermoresistible__bu LGGVDIVVANAGIGPGGQ---TTDDEQWDDVVNVNLKGVWNTLRVAVPTM
MMAR_4754|M.marinum_M LGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHL
MSMEG_5813|M.smegmatis_MC2_155 LGGLDASVANAGVLTAGT-WDTTTSEQWRTVVDVNLIGTWNTCAAALPHL
Mvan_3395|M.vanbaalenii_PYR-1 LGGLDAAVANAGVLTAGT-WDTTTAEQWRTVVDVNLIGTWNTCAAALPHL
Mflv_1905|M.gilvum_PYR-GCK LGGLDAAVANAGVLTGGT-WDTTTAQQWRTVIDVNLIGTWNTCRAAIPHL
MAV_3551|M.avium_104 LGGLDGAVANAGVLTVGT-WDTTTAEQWRLVLDVNLIGAWNTCAAALPHL
MLBr_01740|M.leprae_Br4923 HPSMDIVMNIAGVSVWGT-VDRLTHDQWSNVVAINLMGPIHIIETFVPAI
:* : **: . * :: :** * . * :
Mb2771|M.bovis_AF2122/97 IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
Rv2750|M.tuberculosis_H37Rv IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
MUL_3392|M.ulcerans_Agy99 IEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLA
MAB_3081|M.abscessus_ATCC_1997 VQRGAGGSIVLTSSVAGLTGMVMDNPGGLAYTAAKHGLVGLMRSYANMLA
TH_3757|M.thermoresistible__bu LTQDRGGSIILTSSTGGLIGTPVVSGGMIAYTAAKHGVIGIMRAYANYLA
MMAR_4754|M.marinum_M IAGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVELG
MSMEG_5813|M.smegmatis_MC2_155 VERGG--SVINISSAAGVKGSPLHTP----YTASKHGVVGLSRALANELA
Mvan_3395|M.vanbaalenii_PYR-1 VDRGG--SLVNISSAAGIKGTPLHTP----YTASKHGVVGMSKALANEVA
Mflv_1905|M.gilvum_PYR-GCK LERGG--SLINVSSAAGIKGSPLHTP----YTASKAGVVGMSKALANELA
MAV_3551|M.avium_104 IGGGGG-SLVNISSSAGIKGTPLHLP----YTASKHGIVGMTLALANELA
MLBr_01740|M.leprae_Br4923 LAAGRGGHLVNVSSAAGLVALPWHAA----YSASKYGLRGLSEVLRFDLA
: . :: ** .*: . * *:* .: *: :.
Mb2771|M.bovis_AF2122/97 PQNIRVNSVHPCGVDTPMINNE-FFQQWLT------TADMDAPHNLGNAL
Rv2750|M.tuberculosis_H37Rv PQNIRVNSVHPCGVDTPMINNE-FFQQWLT------TADMDAPHNLGNAL
MUL_3392|M.ulcerans_Agy99 PHSIRVNSLHPSGVDPPMINNE-FIRHWLADL----VAETGSGPGAGNAL
MAB_3081|M.abscessus_ATCC_1997 PHNIRVNTIHPSGVATPMLINP-VTEKLFAD------GSPEGMSDTGNAL
TH_3757|M.thermoresistible__bu PHHIRVNSVAPTTVATPMANNG-DLSMLKKY-------EPAIARSLENAI
MMAR_4754|M.marinum_M QHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTL
MSMEG_5813|M.smegmatis_MC2_155 AVGVRVNTVHPTGVETGMRPDS--LHTLLVE------KRPDLAPIFANAM
Mvan_3395|M.vanbaalenii_PYR-1 AQSVRVNTVHPTGVETGMRPES--LRDLIAQ------QRPDLGPLFLNAM
Mflv_1905|M.gilvum_PYR-GCK AMNIRVNTVHPTGVPTGMRPAS--LHQLLHD------TRSDLSPIFQNAL
MAV_3551|M.avium_104 AQNIRVNTVHPTGVATGMAPPG--MHALIAE------QRPDLVPIFLNAL
MLBr_01740|M.leprae_Br4923 RYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAER
: *. : * * . :
Mb2771|M.bovis_AF2122/97 PVELVQPTDIANAVAWLASEEARYVTGVT---------------------
Rv2750|M.tuberculosis_H37Rv PVELVQPTDIANAVAWLASEEARYVTGVT---------------------
MUL_3392|M.ulcerans_Agy99 PVQILQADDIAGALAWLVSDEARYITGVA---------------------
MAB_3081|M.abscessus_ATCC_1997 PVVLMEPEDMANTVAWLVSEDARYITGVA---------------------
TH_3757|M.thermoresistible__bu PVDYVEARDIANAVAWLASDDARYVTGTV---------------------
MMAR_4754|M.marinum_M PIPWVEAEDISNAVLFLASDESRYITGVT---------------------
MSMEG_5813|M.smegmatis_MC2_155 PIVMAEAIDISNAVLYLVSDESRYVTGLE---------------------
Mvan_3395|M.vanbaalenii_PYR-1 PIQMAEAVDVSNAVLFLVSDESRYVTGLE---------------------
Mflv_1905|M.gilvum_PYR-GCK PIVMAEAVDISNAVLFLISDEARHVTGLE---------------------
MAV_3551|M.avium_104 PAPLIEASDVSNAVLYLISDESRYVTGLE---------------------
MLBr_01740|M.leprae_Br4923 AAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRA
. . . *.: * : *
Mb2771|M.bovis_AF2122/97 -----------LPVDAGFVNKR----------
Rv2750|M.tuberculosis_H37Rv -----------LPVDAGFVNKR----------
MUL_3392|M.ulcerans_Agy99 -----------LPVDAGCVNKR----------
MAB_3081|M.abscessus_ATCC_1997 -----------LPVDAGFTNRR----------
TH_3757|M.thermoresistible__bu -----------VPVDAGLLNKR----------
MMAR_4754|M.marinum_M -----------LPVDAGGCLK-----------
MSMEG_5813|M.smegmatis_MC2_155 -----------FKVDAGVTLR-----------
Mvan_3395|M.vanbaalenii_PYR-1 -----------FKVDAGVTLR-----------
Mflv_1905|M.gilvum_PYR-GCK -----------FKVDAGVTIR-----------
MAV_3551|M.avium_104 -----------LKVDAGVTIR-----------
MLBr_01740|M.leprae_Br4923 LRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
:..* :