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MATDDATGRVAGKRVLITGAARGMGRSHAVRLAEQGADCILVDICCTPTGLDYPLATEEDLNETVRLVEK HGRRAVPKIVDVRDEAAMKAAVDAAVDELGGLDGAVANAGVLTVGTWDTTTAEQWRLVLDVNLIGAWNTC AAALPHLIGGGGGSLVNISSSAGIKGTPLHLPYTASKHGIVGMTLALANELAAQNIRVNTVHPTGVATGM APPGMHALIAEQRPDLVPIFLNALPAPLIEASDVSNAVLYLISDESRYVTGLELKVDAGVTIR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3551 | - | - | 100% (273) | carveol dehydrogenase |
| M. avium 104 | MAV_1921 | - | 1e-63 | 49.45% (271) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_2623 | - | 7e-63 | 49.24% (262) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 8e-57 | 48.86% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1905 | - | 1e-105 | 71.54% (267) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 9e-57 | 48.86% (264) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 3e-22 | 35.96% (203) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3081 | - | 2e-59 | 47.43% (272) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 5e-64 | 51.77% (282) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_5813 | - | 1e-111 | 72.28% (267) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_0236 | - | 9e-62 | 45.96% (272) | PROBABLE DEHYDROGENASE |
| M. ulcerans Agy99 | MUL_3392 | fabG | 5e-55 | 45.79% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_3395 | - | 1e-111 | 75.00% (268) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5813|M.smegmatis_MC2_155 -----MSGRVAGKRVLVTGAARGMGRSHAVRLAEEGADLILLDICESIPE
Mvan_3395|M.vanbaalenii_PYR-1 ----MSAGRVAGKRVLITGAARGMGRSHAVRLAGEGADLILVDICESLPE
Mflv_1905|M.gilvum_PYR-GCK -----MSGRVEGKRVLITGAARGMGRSHAVRLAQEGADLILVDICESLPE
MAV_3551|M.avium_104 MATDDATGRVAGKRVLITGAARGMGRSHAVRLAEQGADCILVDICCTPTG
Mb2771|M.bovis_AF2122/97 ----MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS
Rv2750|M.tuberculosis_H37Rv ----MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS
MUL_3392|M.ulcerans_Agy99 -MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS
MAB_3081|M.abscessus_ATCC_1997 ------MGKLDGKVAFITGAARGQGRAHAIKLASEGASIIAVDICAQIPS
TH_0236|M.thermoresistible__bu ------MGNLEGKVAFITGAARGQGRAHAVRLASEGADIIALDICADIDS
MMAR_4754|M.marinum_M -MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVE
MLBr_01740|M.leprae_Br4923 --MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR------
. *: ::**** * **: *::** **. *
MSMEG_5813|M.smegmatis_MC2_155 -IEYPLATEDELAETVRLVEEHGRHALAH-VVDVRDGEALSAAVTDAVAQ
Mvan_3395|M.vanbaalenii_PYR-1 -IEYPLASPDDLAETARLVEDIGRRAVTH-VVDVRDGAALATAVDDGVAR
Mflv_1905|M.gilvum_PYR-GCK -VEYPLAAVEELADTAELVAQHGRRAVTH-VVDVRDEQALSAAVDDGVAR
MAV_3551|M.avium_104 -LDYPLATEEDLNETVRLVEKHGRRAVPK-IVDVRDEAAMKAAVDAAVDE
Mb2771|M.bovis_AF2122/97 -VPYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGLDE
Rv2750|M.tuberculosis_H37Rv -VPYPLSTADDLAATVELVEDAGGGIVAR-QGDVRDRASLSVALQAGLDE
MUL_3392|M.ulcerans_Agy99 -VPYPLGTAEELATTVKLVEDTGARIVAS-QADVRDREALAAALQAGIDE
MAB_3081|M.abscessus_ATCC_1997 -VEYPMATTEDLDLTVKEVDALGRAISAH-ETDVRDREALQAAFDAGVHD
TH_0236|M.thermoresistible__bu -MDYPNASPADLEETAKLVEGTGRSIVAR-QADVRDADAVDEVVREGVER
MMAR_4754|M.marinum_M NTTIPASTPEDLAETADLVKGHNRRIFTA-EADVRDYDALKAAVDAGVDE
MLBr_01740|M.leprae_Br4923 -------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHAR
* *. . . *: * :
MSMEG_5813|M.smegmatis_MC2_155 LGGLDASVANAGVLTAG-TWDTTTSEQWRTVVDVNLIGTWNTCAAALPHL
Mvan_3395|M.vanbaalenii_PYR-1 LGGLDAAVANAGVLTAG-TWDTTTAEQWRTVVDVNLIGTWNTCAAALPHL
Mflv_1905|M.gilvum_PYR-GCK LGGLDAAVANAGVLTGG-TWDTTTAQQWRTVIDVNLIGTWNTCRAAIPHL
MAV_3551|M.avium_104 LGGLDGAVANAGVLTVG-TWDTTTAEQWRLVLDVNLIGAWNTCAAALPHL
Mb2771|M.bovis_AF2122/97 FGRLDIVVANAGIAMMQ--AGDDG---WRDVIDVNLTGVFHTVQVAIPTL
Rv2750|M.tuberculosis_H37Rv FGRLDIVVANAGIAMMQ--AGDDG---WRDVIDVNLTGVFHTVQVAIPTL
MUL_3392|M.ulcerans_Agy99 LGQVDIVVANAGIAPMQ--SGDDG---WRDVIDVNLSGAYYTVEVAIPTM
MAB_3081|M.abscessus_ATCC_1997 LGPVDIVVANAGIATLTPECGDDG---WRDVLDVNLTGVYHTIEVARPSM
TH_0236|M.thermoresistible__bu FGRLDIVVANAGIVRLSSDEPSQRRQIFRDIIDVNLVGVWNTVEAAIPHV
MMAR_4754|M.marinum_M LGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHL
MLBr_01740|M.leprae_Br4923 HPSMDIVMNIAGVSVWG-TVDRLTHDQWSNVVAINLMGPIHIIETFVPAI
:* : **: : :: :** * . * :
MSMEG_5813|M.smegmatis_MC2_155 VERGG--SVINISSAAGVKGSPLHTP----YTASKHGVVGLSRALANELA
Mvan_3395|M.vanbaalenii_PYR-1 VDRGG--SLVNISSAAGIKGTPLHTP----YTASKHGVVGMSKALANEVA
Mflv_1905|M.gilvum_PYR-GCK LERGG--SLINVSSAAGIKGSPLHTP----YTASKAGVVGMSKALANELA
MAV_3551|M.avium_104 IGGGGG-SLVNISSSAGIKGTPLHLP----YTASKHGIVGMTLALANELA
Mb2771|M.bovis_AF2122/97 IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
Rv2750|M.tuberculosis_H37Rv IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
MUL_3392|M.ulcerans_Agy99 IEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLA
MAB_3081|M.abscessus_ATCC_1997 VQRGAGGSIVLTSSVAGLTGMVMDNPGGLAYTAAKHGLVGLMRSYANMLA
TH_0236|M.thermoresistible__bu INGGQGGSIVITSSSAGLKGTGTDRAGGQAYAAAKRGLVGLMQVWANQLG
MMAR_4754|M.marinum_M IAGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVELG
MLBr_01740|M.leprae_Br4923 LAAGRGGHLVNVSSAAGLVALPWHAA----YSASKYGLRGLSEVLRFDLA
: * :: ** .*: . * *:* .: *: :.
MSMEG_5813|M.smegmatis_MC2_155 AVGVRVNTVHPTGVETGMRP-DSLHTLLVE--KRPDLAPIFA------NA
Mvan_3395|M.vanbaalenii_PYR-1 AQSVRVNTVHPTGVETGMRP-ESLRDLIAQ--QRPDLGPLFL------NA
Mflv_1905|M.gilvum_PYR-GCK AMNIRVNTVHPTGVPTGMRP-ASLHQLLHD--TRSDLSPIFQ------NA
MAV_3551|M.avium_104 AQNIRVNTVHPTGVATGMAP-PGMHALIAE--QRPDLVPIFL------NA
Mb2771|M.bovis_AF2122/97 PQNIRVNSVHPCGVDTPMINNEFFQQWLT--TADMDAPHNLG------NA
Rv2750|M.tuberculosis_H37Rv PQNIRVNSVHPCGVDTPMINNEFFQQWLT--TADMDAPHNLG------NA
MUL_3392|M.ulcerans_Agy99 PHSIRVNSLHPSGVDPPMINNEFIRHWLADLVAETGSGPGAG------NA
MAB_3081|M.abscessus_ATCC_1997 PHNIRVNTIHPSGVATPMLINPVTEKLFAD--GSPEGMSDTG------NA
TH_0236|M.thermoresistible__bu PHSIRVNTIHPTGVATGMVMNETMAKLFE---QGDEALSAMQ------NV
MMAR_4754|M.marinum_M QHMIRVNSVHPTHVRTPMLHNEGTFKMFRP-DLENPGPDDMAPICQLFHT
MLBr_01740|M.leprae_Br4923 RYRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAER
: *. : * * . : .
MSMEG_5813|M.smegmatis_MC2_155 MPIVMAEAIDISNAVLYLVSDE---------SRYVTGLEFKVDAGVTLR-
Mvan_3395|M.vanbaalenii_PYR-1 MPIQMAEAVDVSNAVLFLVSDE---------SRYVTGLEFKVDAGVTLR-
Mflv_1905|M.gilvum_PYR-GCK LPIVMAEAVDISNAVLFLISDE---------ARHVTGLEFKVDAGVTIR-
MAV_3551|M.avium_104 LPAPLIEASDVSNAVLYLISDE---------SRYVTGLELKVDAGVTIR-
Mb2771|M.bovis_AF2122/97 LPVELVQPTDIANAVAWLASEE---------ARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv LPVELVQPTDIANAVAWLASEE---------ARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 LPVQILQADDIAGALAWLVSDE---------ARYITGVALPVDAGCVNKR
MAB_3081|M.abscessus_ATCC_1997 LPVVLMEPEDMANTVAWLVSED---------ARYITGVALPVDAGFTNRR
TH_0236|M.thermoresistible__bu LPIQILQPEDIAEAVAWLVSDA---------GRFITGTAWPLDAGFSVR-
MMAR_4754|M.marinum_M LPIPWVEAEDISNAVLFLASDE---------SRYITGVTLPVDAGGCLK-
MLBr_01740|M.leprae_Br4923 AAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRA
. : : : . * :
MSMEG_5813|M.smegmatis_MC2_155 --------------------------------
Mvan_3395|M.vanbaalenii_PYR-1 --------------------------------
Mflv_1905|M.gilvum_PYR-GCK --------------------------------
MAV_3551|M.avium_104 --------------------------------
Mb2771|M.bovis_AF2122/97 --------------------------------
Rv2750|M.tuberculosis_H37Rv --------------------------------
MUL_3392|M.ulcerans_Agy99 --------------------------------
MAB_3081|M.abscessus_ATCC_1997 --------------------------------
TH_0236|M.thermoresistible__bu --------------------------------
MMAR_4754|M.marinum_M --------------------------------
MLBr_01740|M.leprae_Br4923 LRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN