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MSKTLLGKVALATGGSRGLGAATAEALADRGADVAISYVASDAKAQAVVERLKAKGVRGLAVKSDQADVT AAKPLVDAVIDHFGRLDILVNNAAIAVQGKTVDDPTLDAEEFDRQWHVNVLGTVAVTRAAAQKLSDGGRI VFIGTGFGTRVAFPGVADYAGTKAAILGYAKGVGRDLGPRNITVNVVQPGIMPTDMASEAAANLPDAVMD LHAIRRIATVEEVAASVCFLAGPDAGYITGTVLEVSGGYQI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5596 | - | - | 100% (251) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4351 | - | 4e-40 | 38.71% (248) | oxidoreductase YjgI |
| M. smegmatis MC2 155 | MSMEG_4117 | - | 4e-32 | 33.20% (256) | 2-deoxy-D-gluconate 3-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 5e-30 | 32.65% (245) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_2415 | - | 4e-31 | 33.72% (261) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 5e-30 | 32.65% (245) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-30 | 34.17% (240) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0827 | - | 2e-37 | 38.96% (249) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_2289 | fabG1 | 1e-28 | 31.84% (245) | 3-oxoacyl- |
| M. avium 104 | MAV_0886 | - | 8e-29 | 32.56% (258) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3898 | - | 1e-30 | 38.31% (248) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_1491 | fabG1 | 7e-29 | 31.84% (245) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_5843 | - | 5e-47 | 43.32% (247) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0827|M.abscessus_ATCC_1997 ----------------MTSPLKSRRAFVTGGSRGIGAGIVRRLAEDGARV
Mvan_5843|M.vanbaalenii_PYR-1 ---------------MSTAPLAGKRALVTGGSRGIGAEIVRRLAADGAAV
MSMEG_5596|M.smegmatis_MC2_155 ----------------MSKTLLGKVALATGGSRGLGAATAEALADRGADV
Mflv_2415|M.gilvum_PYR-GCK -----------------MTELAGKVAVVTGGASGIGRGIAARFAAEGAAV
MAV_0886|M.avium_104 ----------------MVNELAGKVAIVTGGASGIGRGIVERFVAEGARV
TH_3898|M.thermoresistible__bu -------------VILDRFRLDDRVAVVTGAGRGLGAAMAVAFAEAGADV
Mb1519|M.bovis_AF2122/97 MTATATEG--------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
Rv1483|M.tuberculosis_H37Rv MTATATEG--------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MMAR_2289|M.marinum_M MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLAADGHRV
MUL_1491|M.ulcerans_Agy99 MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLATDGHRV
MLBr_01807|M.leprae_Br4923 MTDAAAKVS--AAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRV
: .: ..**. *:* . :. * *
MAB_0827|M.abscessus_ATCC_1997 VFTYSSSVQQAADVVDDINEDGGWARAVKADVADPDQLGAAIGQAAEELG
Mvan_5843|M.vanbaalenii_PYR-1 AFTYAASAAHAEKVVAEVAASGGEAVAIRADSADPTQVADAVEQTVAELG
MSMEG_5596|M.smegmatis_MC2_155 AISYVASDAKAQAVVERLKAKGVRGLAVKSDQADVTAAKPLVDAVIDHFG
Mflv_2415|M.gilvum_PYR-GCK VIADVR-DDLGEALVRELNESGAKTVYRHTDVGDQAQVADLVSSTVETFG
MAV_0886|M.avium_104 VIADIE-TERGERLAAEL---GGEAVFRRTDVSDIEQVGALVAAAVEKFG
TH_3898|M.thermoresistible__bu LISART-QAQLEEVAAQIAATGRRAHVVAADLAHPEATAELAGAAVEAFG
Mb1519|M.bovis_AF2122/97 AVTHRGSGAPKG------------LFGVECDVTDSDAVDRAFTAVEEHQG
Rv1483|M.tuberculosis_H37Rv AVTHRGSGAPKG------------LFGVECDVTDSDAVDRAFTAVEEHQG
MMAR_2289|M.marinum_M AVTHRGSGAPEG------------LFGVECDVTDNDAVDRAFKEVEEHQG
MUL_1491|M.ulcerans_Agy99 AVTHRGSGAPEG------------LFGVECDVTDNDAVDRAFKEVEEHQG
MLBr_01807|M.leprae_Br4923 AVTHRASVVPDW------------FFGVECDVTDNDAIGAAFKAVEEHQG
.: * . . *
MAB_0827|M.abscessus_ATCC_1997 GLDILVNNAGILSIGD---VDT--ATLADFDEIVAVNVRAVFAGIKAASP
Mvan_5843|M.vanbaalenii_PYR-1 GLDILVNNSAVAHIAP---IDD--FPAEEFDRLVAINIGGVYWAVRSAIR
MSMEG_5596|M.smegmatis_MC2_155 RLDILVNNAAIAVQGKT--VDDPTLDAEEFDRQWHVNVLGTVAVTRAAAQ
Mflv_2415|M.gilvum_PYR-GCK ALNVMVNNAGISSPLRKGLFHED---LEEFDRVMRVNLLGVMAGTRDAAR
MAV_0886|M.avium_104 GLHVMVNNAGISSPLRR-LLDDD---LADFHRVMGVNVLGVMAGTRDAAR
TH_3898|M.thermoresistible__bu KLDIVVNNVGG--TMPGPLLNTS---AKEMRDAFTFNVGTAHALTTAAVP
Mb1519|M.bovis_AF2122/97 PVEVLVSNAGLSADAFLMRMTEE-----KFEKVINANLTGAFRVAQRASR
Rv1483|M.tuberculosis_H37Rv PVEVLVSNAGLSADAFLMRMTEE-----KFEKVINANLTGAFRVAQRASR
MMAR_2289|M.marinum_M PVEVLVSNAGLSADAFLIRMTEE-----RFEKVIDANLTGAFRVAQRASR
MUL_1491|M.ulcerans_Agy99 PVEVLVSNAGLSADAFLIRMTEE-----RFEKVIDANLTGAFRVAQRASR
MLBr_01807|M.leprae_Br4923 PVEVLVANAGITSDMLIMRMSEE-----QFQKVIDVNLTGVFRVAKLASR
:.::* * . . : *: . *
MAB_0827|M.abscessus_ATCC_1997 HLTEG---GRIVTIGSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGP
Mvan_5843|M.vanbaalenii_PYR-1 YLSEG---ARIINIGSINADRIPGPGLSVYGMTKGAVSSFTRGLARDLGP
MSMEG_5596|M.smegmatis_MC2_155 KLSDG---GRIVFIGTGFGTRVAFPGVADYAGTKAAILGYAKGVGRDLGP
Mflv_2415|M.gilvum_PYR-GCK HMADH-GGGSVINLGSIGG-IQAGGGVSTYRASKAAIIHFTKCAAIELAH
MAV_0886|M.avium_104 HMADN-GGGAIINLTSIGG-IQAGGGVMTYRASKAAVIQFTKAAAIELAR
TH_3898|M.thermoresistible__bu LMLKHSGGGSIINITSTMG-RLAGRGFAAYGTAKAALAHYTRLAALDLAP
Mb1519|M.bovis_AF2122/97 SMQRN-KFGRMIFIGSVSG-SWGIGNQANYAASKAGVIGMARSIARELSK
Rv1483|M.tuberculosis_H37Rv SMQRN-KFGRMIFIGSVSG-SWGIGNQANYAASKAGVIGMARSIARELSK
MMAR_2289|M.marinum_M SMQRK-KFGRLIFIGSVSG-SWGIGNQANYAASKAGVIGMARSIARELSK
MUL_1491|M.ulcerans_Agy99 SMQRK-KFGRLIFIGSVSG-SWGIGNQANYAASKAGVIGMARSIARELSK
MLBr_01807|M.leprae_Br4923 NMIKQ-RFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGS
: . : : : . . * :*..: :: . ::.
MAB_0827|M.abscessus_ATCC_1997 RGITINNVQPGPIGTDMNPEDGQ-------------LADILRPNIAVGRY
Mvan_5843|M.vanbaalenii_PYR-1 RGITVNNVQPGPIDTDANPDDGA-------------FAESLKQVVAQGRY
MSMEG_5596|M.smegmatis_MC2_155 RNITVNVVQPGIMPTDMASEAAAN------------LPDAVMDLHAIRRI
Mflv_2415|M.gilvum_PYR-GCK YEVRVNCLAPGNIPTPILASSATDEDRERLEKFEARIRQQMRDDRPLKRE
MAV_0886|M.avium_104 YDIRVNAIAPGNIPTPILGKSAGDMDPEQRERFEARIREGMREDRPLKRE
TH_3898|M.thermoresistible__bu -RIRVNAIAPGSILTSALDVVASNDE----------LRTPMEQATPLRRL
Mb1519|M.bovis_AF2122/97 ANVTANVVAPGYIDTDMTRALDER------------IQQGALQFIPAKRV
Rv1483|M.tuberculosis_H37Rv ANVTANVVAPGYIDTDMTRALDER------------IQQGALQFIPAKRV
MMAR_2289|M.marinum_M VNVTANVVAPGYIDTDMTRALDER------------IQEGALQFIPAKRV
MUL_1491|M.ulcerans_Agy99 VNVTANVVAPGYIDTDMTRALDER------------IQEGALQFIPAKRV
MLBr_01807|M.leprae_Br4923 RSITANVVAPGFIDTEMTRAMDSK------------YQEAALQAIPLGRI
: * : ** : * . *
MAB_0827|M.abscessus_ATCC_1997 GQPRDIASLVSYLVSDEAWYITGTAINIDGGFTA------------
Mvan_5843|M.vanbaalenii_PYR-1 GHTSDVASLVSFLAGPESGYITGAHLNVDGGFTV------------
MSMEG_5596|M.smegmatis_MC2_155 ATVEEVAASVCFLAGPDAGYITGTVLEVSGGYQI------------
Mflv_2415|M.gilvum_PYR-GCK GTADDVAEAALYLATDRSRYVTGTVLPIDGGTVAGKVIVRKPKDQQ
MAV_0886|M.avium_104 GTPDDVAEAALYFATERSRYVTGTVLPVDGGTSAGKAMRSKRQG--
TH_3898|M.thermoresistible__bu GEPADIAAAAVYLASPAGSYLTGKVLEVDGGLTRPNLDMPIPDL--
Mb1519|M.bovis_AF2122/97 GTPAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH----------
Rv1483|M.tuberculosis_H37Rv GTPAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH----------
MMAR_2289|M.marinum_M GTAAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH----------
MUL_1491|M.ulcerans_Agy99 GTAAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH----------
MLBr_01807|M.leprae_Br4923 GAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH----------
. ::* . ::. . *::* : :.**