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MSPKLTGTVALVTGASSGIGAATARHLAEHGATVALVARRKDRLVTLVADIERDGGAATAVEADVSDRAQ ADAAVAETVQRFGRLDIVVNNAGLMLLGPVAGADAQDWDRMIAVNVSGLLNTTHAALPHLLAAAEDGPRE VADIVNVSSVAGRNASEGYGVYSLTKFGVNGFTESLRQEVTRRHVRVGVIEPGGVNTELGSHNSSAIQAR IIEPFNASVEALAPEDVAESIGYMVTRPRHAAIGELWIMPTEQLV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5569 | - | - | 100% (255) | clavaldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6859 | - | 2e-59 | 52.17% (253) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_5568 | - | 4e-59 | 49.40% (249) | clavaldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0494c | - | 2e-32 | 39.84% (246) | putative short-chain type oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2757 | - | 5e-31 | 36.18% (246) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0484c | - | 2e-32 | 39.84% (246) | short-chain type oxidoreductase |
| M. leprae Br4923 | MLBr_01094 | - | 2e-26 | 33.19% (232) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0827 | - | 2e-31 | 35.29% (238) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_0810 | - | 2e-31 | 38.62% (246) | short-chain type oxidoreductase |
| M. avium 104 | MAV_2980 | - | 6e-67 | 55.02% (249) | clavaldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_1828 | - | 6e-28 | 32.61% (230) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4554 | - | 1e-31 | 38.62% (246) | short-chain type oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3063 | - | 5e-38 | 39.44% (251) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5569|M.smegmatis_MC2_155 -MSPKLTGTVALVTGASSGIGAATARHLAEHGATVALVAR-RKDRLVTLV
MAV_2980|M.avium_104 -MT-TLAHTAALVTGASSGIGAATATALAAEGAAVALLAR-RADRLAELQ
Mb0494c|M.bovis_AF2122/97 MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVAR-RADRITALA
Rv0484c|M.tuberculosis_H37Rv MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVAR-RADRITALA
MMAR_0810|M.marinum_M MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVAR-RADRITALT
MUL_4554|M.ulcerans_Agy99 MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVAR-RADRITALT
Mvan_3063|M.vanbaalenii_PYR-1 MVNDPIDGMVVAITGASSGIGEATARLLGTRGARLVLGAR-RADRLHTLG
MLBr_01094|M.leprae_Br4923 --MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDV-DGEGLAQTE
TH_1828|M.thermoresistible__bu --MQGFAGKVAVITGAGSGIGQALALELGRSGAKVAISDV-NTEGLTETE
Mflv_2757|M.gilvum_PYR-GCK --MGQLSGKVAMVTGASAGLGAETAKLFAERGA-TVFGIARDADRMAEVF
MAB_0827|M.abscessus_ATCC_1997 -MTSPLKSRRAFVTGGSRGIGAGIVRRLAEDGARVVFTYSSSVQQAADVV
. :**.. *:* . :. * . :
MSMEG_5569|M.smegmatis_MC2_155 ADIERDGGAATAVEADVSDRAQADAAVAETVQRFGRLDIVVNNAG-LMLL
MAV_2980|M.avium_104 AEIECSGGTALVVPADVTDAERVAAAVQRTVAEFGRLDILVNNAG-LMQS
Mb0494c|M.bovis_AF2122/97 NQIGGT-----AIVADVTDDAAVEALAR----ALSRVDVLVNNAGGAKGL
Rv0484c|M.tuberculosis_H37Rv NQIGGT-----AIVADVTDDAAVEALAR----ALSRVDVLVNNAGGAKGL
MMAR_0810|M.marinum_M DQIGGT-----PIVADVTDGAAVAALAD----GLSRVDVLVNNAGGAKGL
MUL_4554|M.ulcerans_Agy99 DQIGGT-----PIVADVTDGAAVAALAD----GLSRVDVLVNNAGGAKEL
Mvan_3063|M.vanbaalenii_PYR-1 GELRAAGAEVATVTTDVTAAGDLERLVGTAVADFGRLDVLVSNAG-ISAI
MLBr_01094|M.leprae_Br4923 GQLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAG-IAFT
TH_1828|M.thermoresistible__bu DRLKAIGAPVKADRLDVTERAAFEAYADAVVEHFGVVNQIYNNAG-IAYT
Mflv_2757|M.gilvum_PYR-GCK ADVP--GGSFRSVDVTSADECRR--AVAECVAEFGRLDVLANIAG-FHKM
MAB_0827|M.abscessus_ATCC_1997 DDINEDGGWARAVKADVADPDQLGAAIGQAAEELGGLDILVNNAG-ILSI
: : :. :: : . **
MSMEG_5569|M.smegmatis_MC2_155 GPVAGADAQDWDRMIAVNVSGLLNTTHAALPHLLAAAEDGPREVADIVNV
MAV_2980|M.avium_104 GPATEASLRDWDRMVAVNVQGVLYATRAALPHLVDAAADSPRGVADLVTI
Mb0494c|M.bovis_AF2122/97 QFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD------GLIVTV
Rv0484c|M.tuberculosis_H37Rv QFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD------GLIVTV
MMAR_0810|M.marinum_M EPVADADLEHWRWMWETNVLGTLRVTRALLPKLIASGD------GLIVTV
MUL_4554|M.ulcerans_Agy99 EPVADADLEHWRWMWETNVLGTLRVTRALLPKLIASGD------GLIVTV
Mvan_3063|M.vanbaalenii_PYR-1 GPLADADVTGWDAMIDVNLRGVLHGIAAAMPVFRQQGH------GHFVTT
MLBr_01094|M.leprae_Br4923 GDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGD------GHVINI
TH_1828|M.thermoresistible__bu GDIEVSHFKDIERVMDVDFWGVVNGTKVFLPHLIASGD------GHVINI
Mflv_2757|M.gilvum_PYR-GCK RHTASMTDDDWATDLSVNLNGPFFLCRAALPHLLETGG-------NIVNV
MAB_0827|M.abscessus_ATCC_1997 GDVDTATLADFDEIVAVNVRAVFAGIKAASPHLTE-GG-------RIVTI
.: . . . * : . .:.
MSMEG_5569|M.smegmatis_MC2_155 SSVAG-RNASEGYGVYSLTKFGVNGFTESLRQEV--TRRHVRVGVIEPGG
MAV_2980|M.avium_104 SSTAG-WVARPNTAVYSLTKFGVNAFSEGIRQEV--LGKRVRVGVVGPGT
Mb0494c|M.bovis_AF2122/97 TSIAA-LEVYDGGAGYTAAKHAQGALHRTLRGEL--LGKPVRLTEIAPGA
Rv0484c|M.tuberculosis_H37Rv TSIAA-IEVYDGGAGYTAAKHAQGALHRTLRGEL--LGKPVRLTEIAPGA
MMAR_0810|M.marinum_M TSIAA-LEIYDGGAGYTAAKHAQGALHRTLRGEL--LGLPVRLTEIAPGA
MUL_4554|M.ulcerans_Agy99 TSIAA-LEIYDGGAGYTAAKHAQGALHRTLRGEL--LGLPVRLTEIAPGA
Mvan_3063|M.vanbaalenii_PYR-1 VSTAG-LKIVPTMGVYAATKNAVRTMMEALRQES--TDGVIRTTSISPGY
MLBr_01094|M.leprae_Br4923 SSVFG-LFSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGG
TH_1828|M.thermoresistible__bu SSVFG-LFSVPGQAAYNAAKFAVRGFTEALRQEMILAGHPVKVTTVHPGG
Mflv_2757|M.gilvum_PYR-GCK ASIAG-VEGEVYSAGYCAAKHGLVGLTRALAIEFT--KEKLRVNAICPGG
MAB_0827|M.abscessus_ATCC_1997 GSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFG--PRGITINNVQPGP
* . . * :* . : . : * : : **
MSMEG_5569|M.smegmatis_MC2_155 VNTELGSHNSSAIQAR---IIEPFNASVEALAPEDVAESIGYMVTRP---
MAV_2980|M.avium_104 VDTEIFGHLSEPSRE----AFERQTAGMVMLRPQDIADAVLFMVTRD---
Mb0494c|M.bovis_AF2122/97 VETEFSLVRFDGD----QQRADAVYAGMTPLVAADVAEVIGFVATRP---
Rv0484c|M.tuberculosis_H37Rv VETEFSLVRFDGD----QQRADAVYAGMTPLVAADVAEVIGFVATRP---
MMAR_0810|M.marinum_M VETEFSLVRFDGD----EQRADAVYSGMTPLVAADIAEVIGFVASRP---
MUL_4554|M.ulcerans_Agy99 VETEFSLVRFDGD----EQRADAVYSGMTPLVAADIAEVIGFVASRP---
Mvan_3063|M.vanbaalenii_PYR-1 VNTELDRSITDVA----LRNAVRADMDAFGLAPEAVARAIVFAIEQP---
MLBr_01094|M.leprae_Br4923 IKTAIARNATAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKAR
TH_1828|M.thermoresistible__bu IKTGIARNMTAAEGLDAQELARAFDTKLARTSPEKAAQIILDGVRKNKAR
Mflv_2757|M.gilvum_PYR-GCK MPTAQTTEFEAPENADWDLIMRIASPRG-FMATEDVAKTIAFLASDD---
MAB_0827|M.abscessus_ATCC_1997 IGTDMN-----PEDGQLADILRPNIAVGRYGQPRDIASLVSYLVSDE---
: * . * :
MSMEG_5569|M.smegmatis_MC2_155 ----RHAAIGELWIMPTEQLV-----------------
MAV_2980|M.avium_104 ----RRVAVNHMLVRAAEQTW-----------------
Mb0494c|M.bovis_AF2122/97 ----SHVNLDQIVIRPRDQASASRRATHPVR-------
Rv0484c|M.tuberculosis_H37Rv ----SHVNLDQIVIRPRDQASASRRATHPVR-------
MMAR_0810|M.marinum_M ----PHVNLDQIIIRPRDQASATRRANHQV--------
MUL_4554|M.ulcerans_Agy99 ----PHVNLDQIIIRPRDQASATRRANHQV--------
Mvan_3063|M.vanbaalenii_PYR-1 ----PEVEIGDLTIRPAVQG------------------
MLBr_01094|M.leprae_Br4923 VLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR
TH_1828|M.thermoresistible__bu VLVGTDAKILDAIVRLTG-SGYQRLFPKFVARTMPR--
Mflv_2757|M.gilvum_PYR-GCK -----AAAVHGAVYRVDNGKGAG---------------
MAB_0827|M.abscessus_ATCC_1997 -----AWYITGTAINIDGGFTA----------------
: