For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TGKRLADTVALVTGASSGIGWATARALAAEGATVAVFGRRLARLEELVDVIERDGGRAHAHEVDVTDGAT VARSVQAIADEFGRIDILVNNAGFLANAPAVEADLADWHRTIDVNIGGVLNVTHAALPLVVRAGERERGV ADIVTVSSVGGRRVPGPSSNVYAASKHAVGAFTEALRQELATRRVRVGVVEPGVVRTEMTTGGSKGAPDA TTGAPLDPADIASAIVYMVTRPAHAAVNEILIRPTEQVI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6859 | - | - | 100% (250) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_5569 | - | 2e-59 | 52.17% (253) | clavaldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5568 | - | 1e-48 | 45.97% (248) | clavaldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0494c | - | 6e-35 | 41.22% (245) | putative short-chain type oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3370 | - | 9e-34 | 41.06% (207) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0484c | - | 8e-35 | 41.22% (245) | short-chain type oxidoreductase |
| M. leprae Br4923 | MLBr_01094 | - | 4e-25 | 36.40% (239) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4060 | - | 5e-33 | 38.58% (254) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0810 | - | 3e-36 | 40.94% (254) | short-chain type oxidoreductase |
| M. avium 104 | MAV_2980 | - | 1e-57 | 53.41% (249) | clavaldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_2623 | - | 1e-28 | 34.76% (233) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4554 | - | 2e-36 | 40.94% (254) | short-chain type oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3063 | - | 9e-35 | 36.89% (244) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6859|M.smegmatis_MC2_155 ---MTGKRLADTVALVTGASSGIGWATARALAAEGATVAVFGRRLARLEE
MAV_2980|M.avium_104 ---MT--TLAHTAALVTGASSGIGAATATALAAEGAAVALLARRADRLAE
Mb0494c|M.bovis_AF2122/97 ---MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITA
Rv0484c|M.tuberculosis_H37Rv ---MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITA
MMAR_0810|M.marinum_M ---MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITA
MUL_4554|M.ulcerans_Agy99 ---MTTTDAGNRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITA
MAB_4060|M.abscessus_ATCC_1997 ---MTNPTFDGRVAVVTGASSGIGAATAKSLAALGFHVVVAARREDRVKS
Mvan_3063|M.vanbaalenii_PYR-1 ---MVNDPIDGMVVAITGASSGIGEATARLLGTRGARLVLGARRADRLHT
Mflv_3370|M.gilvum_PYR-GCK MASTDTAQLSGKVAFVTGGASGIGAALVAKLATAGTEVWIADRQIAPAEE
MLBr_01094|M.leprae_Br4923 -----MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQ
TH_2623|M.thermoresistible__bu MGVLDKFRLDDKVVIVTGASSGLGVAFARACAEAGADVVLAARRVERLQQ
.. :**..**:* * . . * :
MSMEG_6859|M.smegmatis_MC2_155 LVDVIERDGGRAHAHEVDVTDGATVARSVQAIADEFGRIDILVNNAG-FL
MAV_2980|M.avium_104 LQAEIECSGGTALVVPADVTDAERVAAAVQRTVAEFGRLDILVNNAG-LM
Mb0494c|M.bovis_AF2122/97 LANQI---GGTAIV--ADVTDDAAVEALAR----ALSRVDVLVNNAGGAK
Rv0484c|M.tuberculosis_H37Rv LANQI---GGTAIV--ADVTDDAAVEALAR----ALSRVDVLVNNAGGAK
MMAR_0810|M.marinum_M LTDQI---GGTPIV--ADVTDGAAVAALAD----GLSRVDVLVNNAGGAK
MUL_4554|M.ulcerans_Agy99 LTDQI---GGTPIV--ADVTDGAAVAALAD----GLSRVDVLVNNAGGAK
MAB_4060|M.abscessus_ATCC_1997 LAGEI---GGTAFV--LDVTDADSVAALTQ----SLDRVDVLVNNAGGAW
Mvan_3063|M.vanbaalenii_PYR-1 LGGELRAAGAEVATVTTDVTAAGDLERLVGTAVADFGRLDVLVSNAG-IS
Mflv_3370|M.gilvum_PYR-GCK LAAQLRATGAVAHAVELDVRDPAAFAHAVHTAVDTSGRLDYLFNNAG-IG
MLBr_01094|M.leprae_Br4923 TEGQLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAG-IA
TH_2623|M.thermoresistible__bu TAEQVRATGRRALTVATDVVDPQQCQEMVDAAMTEFGRVDVLVNNAG-VG
: * . ** . .::: : .***
MSMEG_6859|M.smegmatis_MC2_155 ANAPAVEADLADWHRTIDVNIGGVLNVTHAALP-LVVRAGERERGVADIV
MAV_2980|M.avium_104 QSGPATEASLRDWDRMVAVNVQGVLYATRAALPHLVDAAADSPRGVADLV
Mb0494c|M.bovis_AF2122/97 GLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD------GLIV
Rv0484c|M.tuberculosis_H37Rv GLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGD------GLIV
MMAR_0810|M.marinum_M GLEPVADADLEHWRWMWETNVLGTLRVTRALLPKLIASGD------GLIV
MUL_4554|M.ulcerans_Agy99 ELEPVADADLEHWRWMWETNVLGTLRVTRALLPKLIASGD------GLIV
MAB_4060|M.abscessus_ATCC_1997 GLEPVLEADLEHWRWMWETNVVGTLQVTRALLPKLIDSGD------GLIV
Mvan_3063|M.vanbaalenii_PYR-1 AIGPLADADVTGWDAMIDVNLRGVLHGIAAAMPVFRQQGH------GHFV
Mflv_3370|M.gilvum_PYR-GCK IGGEVDTLTLDDWTDIIDVNLKGVIHGVHAAYPQMIRQGS------GHIV
MLBr_01094|M.leprae_Br4923 FTGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGD------GHVI
TH_2623|M.thermoresistible__bu TAVPATRETPEEFRTVIDINLNGSYWAAQACGRVMRPGSS--------IV
: * * : . .:
MSMEG_6859|M.smegmatis_MC2_155 TVSSVGGRRVPGPSSNVYAASKHAVGAFTEALRQEL--ATRRVRVGVVEP
MAV_2980|M.avium_104 TISSTAG-WVARPNTAVYSLTKFGVNAFSEGIRQEV--LGKRVRVGVVGP
Mb0494c|M.bovis_AF2122/97 TVTSIAALEVYD-GGAGYTAAKHAQGALHRTLRGEL--LGKPVRLTEIAP
Rv0484c|M.tuberculosis_H37Rv TVTSIAAIEVYD-GGAGYTAAKHAQGALHRTLRGEL--LGKPVRLTEIAP
MMAR_0810|M.marinum_M TVTSIAALEIYD-GGAGYTAAKHAQGALHRTLRGEL--LGLPVRLTEIAP
MUL_4554|M.ulcerans_Agy99 TVTSIAALEIYD-GGAGYTAAKHAQGALHRTLRGEL--LGLPVRLTEIAP
MAB_4060|M.abscessus_ATCC_1997 TVTSIAALDVYD-GGSGYTSAKHAQAALHRTLRGEL--LGKPVRLTEVAP
Mvan_3063|M.vanbaalenii_PYR-1 TTVSTAGLKIVP-TMGVYAATKNAVRTMMEALRQES--TDGVIRTTSISP
Mflv_3370|M.gilvum_PYR-GCK NTASMAGLITTS-AQGGYSATKHAVVALSKTMRVEA--ATHGVRVSVLCP
MLBr_01094|M.leprae_Br4923 NISSVFGLFSVP-GQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYP
TH_2623|M.thermoresistible__bu NISSILGITTASLPQAAYSASKAGVIGLTRDLAQQWT-PRKGIRVNAIAP
. * . * :* . : . : : :. : *
MSMEG_6859|M.smegmatis_MC2_155 GVVRTEMT---TGGSKGAPDATTG--APLDPADIASAIVYMVTRPAHAAV
MAV_2980|M.avium_104 GTVDTEIFGHLSEPSREAFERQTAGMVMLRPQDIADAVLFMVTRDRRVAV
Mb0494c|M.bovis_AF2122/97 GAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNL
Rv0484c|M.tuberculosis_H37Rv GAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNL
MMAR_0810|M.marinum_M GAVETEFSLVRFDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNL
MUL_4554|M.ulcerans_Agy99 GAVETEFSLVRFDGDEQRADAVYSGMTPLVAADIAEVIGFVASRPPHVNL
MAB_4060|M.abscessus_ATCC_1997 GAVETEFSVVRFDGDQDRADAVYRGITPLVAEDVAEIIAFVASRPPHVNL
Mvan_3063|M.vanbaalenii_PYR-1 GYVNTELDRSITDVALRNAVRADMDAFGLAPEAVARAIVFAIEQPPEVEI
Mflv_3370|M.gilvum_PYR-GCK GVVRTPILTGGAFGRNKSVSREDQLKLGEALRPMDAGVFAQKALRGVLRN
MLBr_01094|M.leprae_Br4923 GGIKTAIARNATAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKK
TH_2623|M.thermoresistible__bu GFFKSEMTDQYKPGYLDSQMPRVLMGRTGDPEELAATLVWLVSDAGGYVT
* . : :
MSMEG_6859|M.smegmatis_MC2_155 NEILIRP------------------TEQVI---------------
MAV_2980|M.avium_104 NHMLVRA------------------AEQTW---------------
Mb0494c|M.bovis_AF2122/97 DQIVIRP------------------RDQASASRRATHPVR-----
Rv0484c|M.tuberculosis_H37Rv DQIVIRP------------------RDQASASRRATHPVR-----
MMAR_0810|M.marinum_M DQIIIRP------------------RDQASATRRANHQV------
MUL_4554|M.ulcerans_Agy99 DQIIIRP------------------RDQASATRRANHQV------
MAB_4060|M.abscessus_ATCC_1997 DQIVVKP------------------RDQASSTRRATRQ-------
Mvan_3063|M.vanbaalenii_PYR-1 GDLTIRP------------------AVQG----------------
Mflv_3370|M.gilvum_PYR-GCK EAIIVVPRWWKALWYLERLSPALSMRTAAVALKRTREVQSAVPLQ
MLBr_01094|M.leprae_Br4923 ARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR-----
TH_2623|M.thermoresistible__bu GQTIVVDG-----------------GITIT---------------
: