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VPDRVLDGNVVLISGASSGIGNAAARKLAGAGAKVALAARRADKLEGLAERLRSQGHEALVIAADLTDAG NAQSTVDRTVDEFGRLDTLVNAAGVMLNGASEESPLEEWDRMVDINLRGLMYVTKAALPHLLVAARNSPR SVADVVNISSVAGRVAAPTVAIYNATKFAVTGATEAWRQEFTKRNVRFSVIEPGRTKTELFDQKGNSDAD FKAAFGAVEQLHAEDIAEAIAYIVAQPRRVAVNEIVIRPTDQP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5568 | - | - | 100% (253) | clavaldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5569 | - | 4e-59 | 49.40% (249) | clavaldehyde dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6859 | - | 2e-48 | 45.97% (248) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0788c | - | 4e-29 | 34.15% (246) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1263 | - | 3e-28 | 36.68% (199) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0765c | - | 4e-29 | 34.15% (246) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01094 | - | 2e-24 | 34.36% (195) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1215c | - | 1e-29 | 33.74% (246) | short chain dehydrogenase |
| M. marinum M | MMAR_3561 | - | 5e-28 | 35.95% (242) | oxidoreductase |
| M. avium 104 | MAV_2980 | - | 2e-58 | 48.35% (242) | clavaldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_2623 | - | 3e-31 | 41.29% (201) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2794 | - | 2e-27 | 38.14% (215) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3063 | - | 1e-38 | 38.80% (250) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0788c|M.bovis_AF2122/97 -MPRFEPHPARRTTVVAGASSGIGAATATELAGRGFPVALGARRMDKLAE
Rv0765c|M.tuberculosis_H37Rv -MPRFEPHPARRTTVVAGASSGIGAATATELAGRGFPVALGARRMDKLAE
MAB_1215c|M.abscessus_ATCC_199 -MPRFEPHPARRPSIIAGASSGIGAATAIELAGRGFPVALGARRVDKLTE
MSMEG_5568|M.smegmatis_MC2_155 ---MPDRVLDGNVVLISGASSGIGNAAARKLAGAGAKVALAARRADKLEG
MAV_2980|M.avium_104 ---MTT--LAHTAALVTGASSGIGAATATALAAEGAAVALLARRADRLAE
Mvan_3063|M.vanbaalenii_PYR-1 ---MVNDPIDGMVVAITGASSGIGEATARLLGTRGARLVLGARRADRLHT
MMAR_3561|M.marinum_M ------MTSTPPVALITGVSSGIGAAIAVRLASAGFRVVGTSRAPQRLAP
MUL_2794|M.ulcerans_Agy99 ------MTSTPPVALITGVSSGIGAAIAVRLASAGFRVVGTSRAPQRLAP
Mflv_1263|M.gilvum_PYR-GCK --MSDRFSMEGRVAVITGGGTGIGRASALVLAEHGADVVLAGRRAEPLKE
TH_2623|M.thermoresistible__bu MGVLDKFRLDDKVVIVTGASSGLGVAFARACAEAGADVVLAARRVERLQQ
MLBr_01094|M.leprae_Br4923 -----MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQ
::* .:*:* * * . * :. : *
Mb0788c|M.bovis_AF2122/97 LVDKIRADGGEAVAFPLDVTDPESVKSFVAQTVEALGEVELLVSSAGDML
Rv0765c|M.tuberculosis_H37Rv LVDKIRADGGEAVAFPLDVTDPESVKSFVAQTVEALGEVELLVSSAGDML
MAB_1215c|M.abscessus_ATCC_199 LVEKIRSDGGEAVAFPLDVTDADSVKSFVAESIDALGEIDLLVSGAGDMY
MSMEG_5568|M.smegmatis_MC2_155 LAERLRSQGHEALVIAADLTDAGNAQSTVDRTVDEFGRLDTLVNAAGVML
MAV_2980|M.avium_104 LQAEIECSGGTALVVPADVTDAERVAAAVQRTVAEFGRLDILVNNAGLMQ
Mvan_3063|M.vanbaalenii_PYR-1 LGGELRAAGAEVATVTTDVTAAGDLERLVGTAVADFGRLDVLVSNAGISA
MMAR_3561|M.marinum_M IPG--------VETLALDVTDDTAVRSVVSEVIDRTGRIDVLVNNAGLGI
MUL_2794|M.ulcerans_Agy99 IPG--------VETLALDVTDDTAVRSVVSEVIDRTGHIDVLVNNAGLGI
Mflv_1263|M.gilvum_PYR-GCK TAAEVEALGRRALAVPTDVTDADACQALVDTTLAEFGRLDVLLNNAGGGE
TH_2623|M.thermoresistible__bu TAEQVRATGRRALTVATDVVDPQQCQEMVDAAMTEFGRVDVLVNNAGVGT
MLBr_01094|M.leprae_Br4923 TEGQLKAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAF
. . *:. . *.:: : . **
Mb0788c|M.bovis_AF2122/97 PGQLHEVSTEAFAEQVQIHLVGANRLATAVLPAMVARRRG------DLIF
Rv0765c|M.tuberculosis_H37Rv PGQLHEVSTEAFAEQVQIHLVGANRLATAVLPAMVARRRG------DLIF
MAB_1215c|M.abscessus_ATCC_199 PGRVHEMSAATFAAQIQVHLLGANQLATEVVPDMVSRRRG------DVVF
MSMEG_5568|M.smegmatis_MC2_155 NGASEESPLEEWDRMVDINLRGLMYVTKAALPHLLVAARNSPRSVADVVN
MAV_2980|M.avium_104 SGPATEASLRDWDRMVAVNVQGVLYATRAALPHLVDAAADSPRGVADLVT
Mvan_3063|M.vanbaalenii_PYR-1 IGPLADADVTGWDAMIDVNLRGVLHGIAAAMPVFRQQGHG------HFVT
MMAR_3561|M.marinum_M AGAAEESSIDQARSLFDTNFFGLIRLTNEVLPHMRRRGSG------RIIN
MUL_2794|M.ulcerans_Agy99 AGAAEESSIDQARSLFDTNFFGLIRLTNEVLPHMRRRGSG------RIIN
Mflv_1263|M.gilvum_PYR-GCK TKSLMKWTDDEWHHVLDLNLSSAWYLSRAAAKPMIAQGSG------AIVN
TH_2623|M.thermoresistible__bu AVPATRETPEEFRTVIDINLNGSYWAAQACGRVMRP-GS-------SIVN
MLBr_01094|M.leprae_Br4923 TGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDG------HVIN
. . . : .:
Mb0788c|M.bovis_AF2122/97 VGSDVGLR--QRPHMGAYGAAKAGLAAMVTNLQMELE--GTGVRASIVHP
Rv0765c|M.tuberculosis_H37Rv VGSDVGLR--QRPHMGAYGAAKAGLAAMVTNLQMELE--GTGVRASIVHP
MAB_1215c|M.abscessus_ATCC_199 IGSDVALH--QRPHMGAYGAAKAALLAMVNTMRMELE--GTGVRASIVHP
MSMEG_5568|M.smegmatis_MC2_155 ISSVAGRV--AAPTVAIYNATKFAVTGATEAWRQEFT--KRNVRFSVIEP
MAV_2980|M.avium_104 ISSTAGWV--ARPNTAVYSLTKFGVNAFSEGIRQEVL--GKRVRVGVVGP
Mvan_3063|M.vanbaalenii_PYR-1 TVSTAGLK--IVPTMGVYAATKNAVRTMMEALRQEST--DGVIRTTSISP
MMAR_3561|M.marinum_M ISSVLGFL--PAPYAALYAASKHAVEGYTESLDHELR--EYGVRALLVEP
MUL_2794|M.ulcerans_Agy99 ISSVLGFL--PAPYAALYAASKHAVEGYTESLDHELR--EYGVRALLVEP
Mflv_1263|M.gilvum_PYR-GCK ISSGAGL--LAMPQAPIYGAAKAGLQNLTGSMAAAWT--RKGVRVNCIAC
TH_2623|M.thermoresistible__bu ISSILGITTASLPQA-AYSASKAGVIGLTRDLAQQWTP-RKGIRVNAIAP
MLBr_01094|M.leprae_Br4923 ISSVFGLF--SVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYP
* . * * :* .: :. :
Mb0788c|M.bovis_AF2122/97 GPTLTGMGWQLSAEQVGPMLADW----AKWGQARHNYFLRPSDLARAIAF
Rv0765c|M.tuberculosis_H37Rv GPTLTGMGWQLSAEQVGPMLADW----AKWGQARHNYFLRPSDLARAIAF
MAB_1215c|M.abscessus_ATCC_199 GPTLTSMGWQLSAEQVGPMLEDW----KSWGQARHSYFLRPSDIARAVTF
MSMEG_5568|M.smegmatis_MC2_155 GRTKTELFDQKGN-SDADFKA----------AFGAVEQLHAEDIAEAIAY
MAV_2980|M.avium_104 GTVDTEIFGHLSEPSREAFER----------QTAGMVMLRPQDIADAVLF
Mvan_3063|M.vanbaalenii_PYR-1 GYVNTELDRSITDVALRNAVR----------ADMDAFGLAPEAVARAIVF
MMAR_3561|M.marinum_M SYTRTDFESNMWEADTPQAAYADNRAAVRAVVADKIRNAELPAVVADATY
MUL_2794|M.ulcerans_Agy99 SYTRTDFESNMWEADTPQAAYADNRAAVRAVVANKIRNAELPAVVADATY
Mflv_1263|M.gilvum_PYR-GCK GAVRTPGLEADAKRQGFDIDMIG-------QTNGSGRIAEPDEIGYGVLF
TH_2623|M.thermoresistible__bu GFFKS-EMTDQYKPGYLDSQMPR-------VLMG--RTGDPEELAATLVW
MLBr_01094|M.leprae_Br4923 GGIKTAIARNATAAEGLDVSKIAS------RFDTWVAHTSPQHAARIILK
. :
Mb0788c|M.bovis_AF2122/97 VAETPRGCVVVNMEIQPEAPLRDAPAHRQKLVLGEEGMPG----------
Rv0765c|M.tuberculosis_H37Rv VAETPRGCVVVNMEIQPEAPLRDAPAHRQKLVLGEEGMPG----------
MAB_1215c|M.abscessus_ATCC_199 VAETPRGAHIPEMEVQPEAPLKDAPADKQKLELGEEGMPS----------
MSMEG_5568|M.smegmatis_MC2_155 IVAQPRRVAVNEIVIRPTDQP-----------------------------
MAV_2980|M.avium_104 MVTRDRRVAVNHMLVRAAEQTW----------------------------
Mvan_3063|M.vanbaalenii_PYR-1 AIEQPPEVEIGDLTIRPAVQG-----------------------------
MMAR_3561|M.marinum_M AAATDKRIKLRYPAGRHARQLALLKRIAPAAVLDNGIRKQTGLNSPRPTP
MUL_2794|M.ulcerans_Agy99 AAAIDKRIKLRYPAGRHARQLALLKRIAPAAVLDNGIRKQTGLNSPRPTP
Mflv_1263|M.gilvum_PYR-GCK FASDASSYCSGQTLYMHGGPGPAGV-------------------------
TH_2623|M.thermoresistible__bu LVSDAGGYVTGQTIVVDGGITIT---------------------------
MLBr_01094|M.leprae_Br4923 AVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR----
Mb0788c|M.bovis_AF2122/97 -----
Rv0765c|M.tuberculosis_H37Rv -----
MAB_1215c|M.abscessus_ATCC_199 -----
MSMEG_5568|M.smegmatis_MC2_155 -----
MAV_2980|M.avium_104 -----
Mvan_3063|M.vanbaalenii_PYR-1 -----
MMAR_3561|M.marinum_M VLAER
MUL_2794|M.ulcerans_Agy99 VLAER
Mflv_1263|M.gilvum_PYR-GCK -----
TH_2623|M.thermoresistible__bu -----
MLBr_01094|M.leprae_Br4923 -----