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M. thermoresistible (build 8) TH_4326 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 406377 - 407153
length: 259

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4326 - - 100% (259) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_1383 - 2e-28 31.66% (259) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8) TH_3893 - 2e-24 37.43% (187) PUTATIVE putative short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1571 - 6e-46 40.46% (262) ketoacyl reductase
M. gilvum PYR-GCK Mflv_0244 - 1e-112 79.07% (258) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1544 - 6e-46 40.46% (262) ketoacyl reductase
M. leprae Br4923 MLBr_00429 - 4e-36 35.60% (250) putative oxidoreductase
M. abscessus ATCC 19977 MAB_4261c - 4e-98 69.14% (256) putative short chain dehydrogenase/reductase
M. marinum M MMAR_0648 - 1e-101 70.16% (258) ketoacyl reductase
M. avium 104 MAV_4791 - 1e-103 70.93% (258) dehydrogenase
M. smegmatis MC2 155 MSMEG_0737 - 1e-111 77.52% (258) dehydrogenase
M. ulcerans Agy99 MUL_0124 - 1e-100 69.77% (258) ketoacyl reductase
M. vanbaalenii PYR-1 Mvan_0661 - 1e-113 79.07% (258) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0244|M.gilvum_PYR-GCK          -----MTRP----VALITGPTSGLGEGFARRYAVDGYDLVLVARDESRLN
Mvan_0661|M.vanbaalenii_PYR-1       -----MSRP----VALITGPTSGLGEGFARRYAVDGFDLVLVARDVERLN
TH_4326|M.thermoresistible__bu      -----MPRP----VALITGPTSGLGEGFARRYAADGHDLVLVARDVQRLE
MSMEG_0737|M.smegmatis_MC2_155      -----MPRP----VALITGPTSGLGAGFARRYALEGYDLVFVARDQQRLE
MAB_4261c|M.abscessus_ATCC_199      MAATNSARP----VALITGPTSGLGGGFARKYASQGYDVVLVARDEQRLG
MMAR_0648|M.marinum_M               -----MPRP----VALITGPTSGIGAGYARRYAQDGYDLILVARDVDRLK
MUL_0124|M.ulcerans_Agy99           -----MPRP----VALITGPTSGIGAGYARRYAQDGYDLILVARDVDRLT
MAV_4791|M.avium_104                -----MPRP----VALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLT
Mb1571|M.bovis_AF2122/97            ---MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLD
Rv1544|M.tuberculosis_H37Rv         ---MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLD
MLBr_00429|M.leprae_Br4923          ---MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLV
                                          . *     .::**.:..:*   *   *  *. ::.:**  . * 

Mflv_0244|M.gilvum_PYR-GCK          TLAAELRDEAGTAVEVIRADLADDADRALVADRLRAG-VQVLVNNAGFGT
Mvan_0661|M.vanbaalenii_PYR-1       RLAAELHDEAGTNVEVIRADLADAADRAVVADRLRAG-VRVLVNNAGFGT
TH_4326|M.thermoresistible__bu      QLAAELRQSAGIDVEVLPADLAVAADRAKVADRLADG-VQVLVNNAGFGT
MSMEG_0737|M.smegmatis_MC2_155      QLADELHHEAGATVETIAADLAVADDRARVAERVRQG-VRVLVNNAGFAT
MAB_4261c|M.abscessus_ATCC_199      ALADELTCRFGVYAEALPADLADAADRARVADRLAAG-VSVLVNNAGFAT
MMAR_0648|M.marinum_M               QLAVELEDDAG-NVEILPADLADAAGRDKVAERLSRG-VRVLVNNAGFAT
MUL_0124|M.ulcerans_Agy99           QSAVELEDDAG-NVEILPADLADAAGRDKVAERLSRG-VRVLVNNAGFAT
MAV_4791|M.avium_104                ALAGELRDRAG-NIEILPADLGDAVDRQRVGERLAGG-VRVLVNNAGFAT
Mb1571|M.bovis_AF2122/97            ELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGT
Rv1544|M.tuberculosis_H37Rv         ELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGT
MLBr_00429|M.leprae_Br4923          DLAARLADKYRVAVEVRPADLTDPSERVKLADELTVRPISILCANAGTAT
                                      * .*        *    **     *  :.:.:    :  *  .** .*

Mflv_0244|M.gilvum_PYR-GCK          SGEFWTTDYAVLQSQLDVNVTAVMQLTHAALPSMLDAGRGTVLNVASVAG
Mvan_0661|M.vanbaalenii_PYR-1       SGEFWSADYALLQTQLDVNVTAVMQFTHAALPPMLAAGEGTVLNVASVAG
TH_4326|M.thermoresistible__bu      SGEFWTADPTLLQAQLDVNVTAVMHLTHAALPPMLDAHRGTIINVASVAG
MSMEG_0737|M.smegmatis_MC2_155      SGEFWTADFARLRAQLDVNVTAVMELTHAALPAMLDAHEGTIINVASVAG
MAB_4261c|M.abscessus_ATCC_199      AGEFWTAAPELLHSQLDVNVTAVMELTRAALPSMIEAGAGTVINVASVAG
MMAR_0648|M.marinum_M               SGEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGTVINIASVAG
MUL_0124|M.ulcerans_Agy99           SGEFWETEPAALQAQLDVNVTAVMQLTRAALPPMLAAGAGTVINIASVAG
MAV_4791|M.avium_104                SGDFWHTDPALLQSQLDVNVTAVMHLTRAALPAMLDAGAGTVINIASIAG
Mb1571|M.bovis_AF2122/97            SGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAG
Rv1544|M.tuberculosis_H37Rv         SGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAG
MLBr_00429|M.leprae_Br4923          FGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAG
                                     * .          :: :*. *: .:* *.** *:    * ::  .* **

Mflv_0244|M.gilvum_PYR-GCK          LLPG-RGSTYSASKAWVVSFTEGLANGLDGTGVGVHALCPGFVHTEFHER
Mvan_0661|M.vanbaalenii_PYR-1       LLPG-RGSTYSASKAWVVSFSEGLANGLGGTGVGVHALCPGFVHTEFHER
TH_4326|M.thermoresistible__bu      LLPG-RGSTYSASKAWVIAFSEGLANGLTGTGVGIHVVCPGFVRTEFHQR
MSMEG_0737|M.smegmatis_MC2_155      LVPG-RGSTYSASKAWVVSFTEGLANGLIGTGVGVHALCPGFVRTEFHAR
MAB_4261c|M.abscessus_ATCC_199      LVSG-RGSTYSASKAWVVSFTEGLANGLLGTGVGMHVLCPGFIHTEFHER
MMAR_0648|M.marinum_M               LLSG-RGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPGYVHTEFHAR
MUL_0124|M.ulcerans_Agy99           LLSG-RGSTYSASKAWVISFSEGLSTGLEGTGVGVHAVCPGYVHTEFHAR
MAV_4791|M.avium_104                LLPG-RGSTYSASKAWVISFSEGLSVGLQGTGVSVHAVCPGYVRTEFHAR
Mb1571|M.bovis_AF2122/97            FQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEI
Rv1544|M.tuberculosis_H37Rv         FQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEI
MLBr_00429|M.leprae_Br4923          NSPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDH
                                      .    :.*:*:**:. :*:*.:   * *:** :  :.** : **    

Mflv_0244|M.gilvum_PYR-GCK          AGID--MAGTAGFLWLEVDDVVRETMADVAKNRVVIIPGLQYKALTTGGR
Mvan_0661|M.vanbaalenii_PYR-1       AGID--MAGTASFLWLEVDDVVRETMASIAKHKVVIIPGLQYKALTTGGR
TH_4326|M.thermoresistible__bu      AGID--MSGTPSILYLDVDDVVRTTVARVRKGDVVIVPGLQYKVLTTVGR
MSMEG_0737|M.smegmatis_MC2_155      AGID--MAGTPSFMWLEVDDVVRDCLADVAKDKVVIVPGLQYKALTTGGR
MAB_4261c|M.abscessus_ATCC_199      AGIE--MGTIPEFMWLQVDDVVNACLHDIAAGKVLIVPGVQYKAITSVTR
MMAR_0648|M.marinum_M               AGID--MTKLPSFMWLDVDDVIQESLADIADGKVISIPGVQYKALVGAGR
MUL_0124|M.ulcerans_Agy99           AGID--MTKLPSFMWLDVDDVIQESLADIADGKVIGIPGVQYKALVGAGR
MAV_4791|M.avium_104                AGID--MSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAER
Mb1571|M.bovis_AF2122/97            ASA---ERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGR
Rv1544|M.tuberculosis_H37Rv         ASA---ERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGR
MLBr_00429|M.leprae_Br4923          DEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKAMSVASR
                                                :  :. ...    :  :       :**:  * :    *

Mflv_0244|M.gilvum_PYR-GCK          LVPRNVVRALTKVVGKGRGRT---
Mvan_0661|M.vanbaalenii_PYR-1       MVPRNLVRALTKVVGKGRGRT---
TH_4326|M.thermoresistible__bu      LVPRKLVRALTKVVGKGRGRT---
MSMEG_0737|M.smegmatis_MC2_155      MAPRNLVRAVTKVVGKGRART---
MAB_4261c|M.abscessus_ATCC_199      LIPRGLVRKYNSVVGRGRGRT---
MMAR_0648|M.marinum_M               MIPRGLLRAVMKRVGGGRGRT---
MUL_0124|M.ulcerans_Agy99           MIPRGLLRAVMKRVGGGRGRT---
MAV_4791|M.avium_104                LIPRTLMRAITKRVGGGRGRT---
Mb1571|M.bovis_AF2122/97            FAPRSLLLPAIR-IGNRLRGGPSR
Rv1544|M.tuberculosis_H37Rv         FAPRSLLLPAIR-IGNRLRGGPSR
MLBr_00429|M.leprae_Br4923          YAPRAIVASIVGNFYKKLGGG---
                                      ** ::      .

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4326	-	-	100% (259)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_1383	-	2e-28	31.66% (259)	PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)	TH_3893	-	2e-24	37.43% (187)	PUTATIVE putative short-chain dehydrogenase/reductase SDR